Basic Information

Insect: Poecilus cupreus
Gene Symbol: TMEM50B
Assembly: GCA_963942605.1
Location: OZ012725.1:5915313-5924877[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00012 0.024 16.6 0.9 1 23 261 283 261 283 0.98

2 8 0.084 16 7.8 3.7 1 21 289 309 289 313 0.83

3 8 0.093 18 7.6 0.1 2 20 561 579 560 581 0.92

4 8 4.8e-06 0.00092 21.1 2.1 1 23 1252 1274 1252 1274 0.99

5 8 2.5e-06 0.00048 22.0 4.2 1 23 1280 1304 1280 1304 0.92

6 8 9.8e-06 0.0019 20.1 0.9 3 23 1829 1849 1828 1849 0.97

7 8 0.00042 0.08 15.0 2.2 1 23 1855 1879 1855 1879 0.92

8 8 0.00093 0.18 13.9 2.7 1 23 1897 1921 1897 1921 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00012	0.024	16.6	0.9	1	23	261	283	261	283	0.98
2	8	0.084	16	7.8	3.7	1	21	289	309	289	313	0.83
3	8	0.093	18	7.6	0.1	2	20	561	579	560	581	0.92
4	8	4.8e-06	0.00092	21.1	2.1	1	23	1252	1274	1252	1274	0.99
5	8	2.5e-06	0.00048	22.0	4.2	1	23	1280	1304	1280	1304	0.92
6	8	9.8e-06	0.0019	20.1	0.9	3	23	1829	1849	1828	1849	0.97
7	8	0.00042	0.08	15.0	2.2	1	23	1855	1879	1855	1879	0.92
8	8	0.00093	0.18	13.9	2.7	1	23	1897	1921	1897	1921	0.93

Sequence Information

Coding Sequence: ATGGAAATCTCTGGGAACAAATATTTGCACAAAAAGTTTAAGAAACAAACAAGCTGTAACCCTGTTTACAACGTAGAAGATAAGAATGATAACAGCGTGTTGGCCACCGCTAGCAACACTAACAACGGGGAGCGTACGAGCTCCAATGAAGAGGaacctgttaattttttattatttaaggaCAATAAACTCGTAGGAAGTGTGCCAAATTACAAGAGTACAAATTGTGACGGTAGTTTAGTCATCGAATCACAAGATAGCGAGAGAACTGTAGAGAGAAGCGCGAACACGAATGTTAAATTAGATAATCAGTCTTCCATATCAAACGTAGAAGTAAGTGTGAATATAGCGACGAATAGCAGTGTAACCAAGGAACCAGTAGATTGTTACAATAAGTATCGGACGTCCGACGATCAGAAAATCCGATCGCTGGAACCCCAAACCATCTCGACATCAAACGTAACTAGCTGCATATCAAAATTAATCACTACAACTACTACTAGTTTGTTAGGCAATGAGTTAAAAGAAAACAGCATAAGAAATTTTAGTTTTGATACTAAAGTTAGTATTTCTGAACCAATCCCGAACATTGAGAAGTCTTCCATTTTAGATACCGTATATTCTAAATCTAGTTTAATATCAGAACGGCCAAATGCAGCGGGTATCAAATTAGATGTAGACGAATCTACGCATAGAGTCGGTAGAACCGATGCCGATAGTAGCAACACCTCGGAAAACATCCTGGAGAAGAAAAACTGTACGGAATCCACTGGCGGAAAGTATGTTTGCACATATTGCAACTTGGCGTGTTCAAAACCAAGTGTGTTGCAAAAACACATTCGCGCCCACACAAATGAGCGGCCCTATCCATGTATAAGTTGCGGATTTAGTTTCAAAACAAGATCTAACTTGTACAAGCACTGCAGATCAAGAACGCACGCGAATCGAGTTATGGGCAACAAACACGTTCAAGCTGGTCAAATGGAAACTTTAGATGTTGATGGCTCTTCGGAAAAAAGTGAAGATCGACTGGACTGCACAGAAGAAACAGAAGATAATAAAAACATGTCTATTATGGATGATAAACCTCCGAAATCGATGGAAATCAATTTGGATAATGCTATCCAGTCAAATCCGGATGTTGTGATAACACCCGACCAAAGGAATGTTTGGGAACAAAAATCAAAACCATACAAACCACGATTTCACacagcaaaattatttttcgaagAAAATAAGTTGAAAGAGAATGATGCGAAACTGGATAACGTTTCTAATCTCCCACAAATTCATATAAAATCACCTAGGAAATCTCCCAACCCGGAAATCATGAAAAATAGAGTAGAATTACATGAACCACAAATTATCAGAACTAATCCTGATTTATTAAAACTTAGAATAAAtgaacttataaataaaaataattccatAGTTAACTGCGATGATGCTGTTGTGATTAGAAGaagaaatatggaaaatattatagaaaataataacgAATATTTTCCATCGCATCATGTGCAATGGCATCATCAACCAGCAGAATACAGAAATACTATAGATGAACCTTTAAATTTAACAGCTAAAAACAGAAAACGTTGCTTAAGTGATTCAgacaatacaaataaaagtttaattaaagaattactaCTTAAAAATTTGAGTAGCGATCCAAATCTTCAGTGTCCATATTGTAAAATGATTTTCCAAACTGTTACTGAGTtagaaatgcataaaataaaatattgcaatgCAAAACACAGCAACATAAGATACGCAAGAAGTAGTTCAGTAAATGTTGCTTCCATTttaactcaaaataaaaatgctttcgACAATATTCCCCATATGCAGCATACAACGTTTCCTTTAAAATCTCCTGGACCATGTTTAGGGAAAACAAGATTGATTGACAGCGAGAAACCCGGAGAAAAATACAGAACATTCTCTTTTGATGATAATGTTATTATGCATCATAGTCAATCTGATTCTCCtagttttaacaaatatatgcTCCAATCTCCTGTTGGTAGTTATCCCCTTTCTccccaaattaaaaaaaatcctatcaaattatttggaGGTGAAGTTAAAATCACCCAAACATCCGGAGAAACAAGAAGTTTCAAAATCGAATCAGAAAGCATCAATAAAATGGAAGAACCACATCATTTTATGGAATTCAGTGGAAATTTAAGTGAAAATTTGGTTATTAAATCAACTTTACAATCTGGTGGAACTGTATTACAAAATAAGGCAAACTATAGCCCAAAAATGGATAGTCTACCTTCGCCTAATATTATTAGAGTTTATGAAAACGCCGAAATGTCGCCATCAAATTTAAATCTACCAATATTGAACGACAAATCTAAATTTACATATGATAAGATCTCACAACCCAATATAAGGCAGAATGATAAACTTTTAATTGTAGCAAACAATGAAATGCTGATGAAGAGAAGATTTCCTGTGAGAGATAAAATGGAACAGAACTATACTGATAACTCAGTTCGAAATACAGACATCAAATCAGATTCTGAGAAAGATAAAGAAATATACAAATCGAATTTAATGGACTTTGGCCAAAAAGCAGTTAAACTTCTAGCACCAAATTTAAAACCTCCAAACTTAACGATACCTGGCTTGCCGATACCTTCAGCTCCAGGAGATAACTTAATGTCTTCTCCAATTGTTACAATTGCCCCTTTAGAAATAAACACTTCTTTAATGGATAATATAATAGATAGACAGCACCAAGAAAATCTTAATTTCGccaaaaaacaaatttctttgCAACAACGAATGGCAGAAGTATCTCAACCACAAACTGTTTTCAATCCGATGAATATTGTAGTGAATGGAAAAGTTATTCGTTACGTTCCTGGTATGCCAGGACCTGTAGTTGCTGATACACCGGCTGAAATGGCATTCAATCCTGCAAATACTAGGTTAACTCCTACAAGTAAATTACCAAAATCTCCTAGGCCTTTTGATGACCCTCGAGAAGTTAAAGAAAAAGTTGAAACTCCAACATCAATGCTTCCAGTTTTAAACGGCGTACAATTCGAAAGAAAAACACCAACTATAATTGTAGACCAACATGATAATAAGCCCCCAGAACCAAAACTTTTAATACAAAATCGAGAAAGAATTAATTTGGTCAGCAGAGTTTCTGAAAGTAAAGTTAGTCCAACTGCAACAGTTTCAAGTCCAGAAAAAACTTCCAAAGAAGAATCACGAAAATTCGTTCGTCCAACTAGCCTAGCACTAAAACCAAACTCTGTAGCTTTTAAAAATCATCACGGCTTAACACCAACGATGTTTAATCAAGCCTTAATCAGTCCTGATACTCCAAGAGTAGCTAAAAAGTATTGCCAGCaatatttaaatggaaattaCTTCAGTTATCTTGGACTCAAAAGTTCTACAAAATCTGTATATTGCACATTAAACAAGACGCAGCCCTTTTATGTGAAGCATTTTAAAAAGCTGAGCATGTATTCCGAATGGAGACAACAGGAAAGCAAAATTGACAGCTTGAGTGTTAGTGCATATGATTCTAGGCAAAGGCAACAGAAGTATACGATGAGTGGACATGCGCAAGCAAATTTGGTAGCACATTCAAGTTACAAGTTTGTAAAAACAGAAACACCAACTTCAAAAGaagaaaaggaaaataaaaattcatcagTTCTTGGTGGTTACGAATCTAATGAAGACTACACTTATATTAGAGGTAGAGGTCGGGGGCGTTATGTTTGCGACCAATGTGGAATTCGGTGTAAAAAACCATCAATGTTAAAGAAACACATTAGGACACATTCTGATGATCGTCCTTACACATGTGAACATTGCAATTTCAGttttaaaacaaaaggaAACCTAACAAAACATATGAAGAGCAAAGCACATTCGAAAAAATATGCGGCTACTAGCAGTACCTCGACGCAAAATAGTGTTACAAGTTCGGAATCTGAAGATAGCGATGCAGAAAGTAGTGATGAATCAACTAGACTACAAGAACATGAGGCAGCCCATTGTTTATTATCTTTGTCTCAAAAGAATACCCAGCCTGTATCAAGCATCACCCAAGAATCAAATTCTTCTTCAACTAGCCCATTTTCTTCTTCAAGTACTACAGTATCTTTCAGTTTAACAGAATTTCCTAATTTCTTAAAAGATGATAAGTTTCTTAAAAACCCAGATCAGATAAATCAAGttgcaaatacaaattttgcgAAAAACAAGATCTTGGATGAAAATCCGGTAAATTTTAACGCTACAAAACACTTAACCGAAGTGTTTGACGTTCCTACCACTTCAAGCCAAGATTCTAGTAATGTTTCGCAATATTTAGGAAAATCTTCAACAATAAGACCTTTGACTTATCCATACCAACAAACGCAATTTGATTTAGATAaagataaatctaaaaatagTGAAAACTTAGATCACATTCCAAAAATAATAACTTCAGCGCAACAGGAAATGCATCAAAGATTAATCAAACCtgtagaaaacaaatttattatttcgaaTAGTAGAGAATCTATTTCTCAAGAGCAGAAATAcccagaaataaaatttaaaagaatggaCGAAGTTAAACAGACCGTGAGTAGTTCGCAAATGAGTCTACCTATTATACGACAAGATTTTTCGCCGCAAAATGTTGAAGGAAATCTTCCAGCAAATATAGTTTTCCGAAAACGAAAATTGTCTACCTCCAGTAATGTTCAGTATAAGGTACAACGAAGCGATGTAGAACCAAGTTCGAAAGCTGTAGATCTCTCAATGCCAATAATCCAGGATTCTCCGATTTTGGATTTATCCCCTGCTGCCGTCAACGGTGAACCTATATCTTTTAACGGTGCTTTTATTTCGTCTAATAATAACgatagtttaaataacaaattaagtgcTTCTATTTcaaaaagaactttaattttaaatcacgAAAATCATATTAATCCACCTAGAACTGTTGATGTTATATCAGATCCTCAAATAATGTACAACGTTGTGAATAGTGAAAGAGTTAGCGAACCTTTGATTGTTTACAATCAAATACAAAAACCTCGTCATAACAGTTTTTCCGAATCAAATAGCAGTGAAACCTTTTCACAAAGCAGCGATACAAATGATAGGGTGATAGGAAAAATGGTTGACATACCTGAAAATTCAATGCCATctgataaaattgaaatgtacaAATCTAGCGTGCAGGTTGATATTGCACGAAGTCAGTCAAAAACTCCTGATTATGGGGAGCAGGATCAGTCGGCTATGCAGACTCTTGCAGAAATTGCcataaaacaagtaaaattagAGAAGAATATTCTAGCAAAAAATGTTGCTTCGGAATATTTAAAGTTAGCTCTGAATAATGAAGGGAGTAATCAAGATGGAAACATGAAGAAATTTGCTTCTAGTACAAAGGAACCTGTCAACGAGCTGATGGTCAAACctgaagaaagtaaaaattgttcgATTTGTTCGAAGAACTTCAGCAAGCCATCGCAGTTAAGgtTACACATGAATATCCATTACTTAGAACGTCCATTCCGTTGCGAATCATGTTCAGTTAGTTTTAGAACAAGAGGCCACTTACAAAAACACGAAAGAAGTGCTAGTCATCATAATAAGTTATCCTCGTCTCCGGCGTTATCTTCGCAGGAACCTCGGCCTTTCAAGTGTTCCGATTGTAACATTGCTTTTCGGATACACGGGCATTTAGCTAAACACTTAAGATCGAAAATGCACATAATGAAGCTTGAATGTTTAGCGAAAATACCTTTCGGCCTATACGCTGAATTAGAAAGAGCGAATAGTTTGTTAACGGAGATTAACACGACGGACGGCGATTTATGTTTAGAAAGTTTGAAGatTTTAGCGAGGAAGTTGTTCAGCAACGACCCTAGTAAGCTGGACCAGTTGGATGCAGCTACTGTTTACCCTAATTTAATGTCAGGTGCTTACCATGTCTGTGGAATATTTGGAACTCTTTCGTTAGTTATGGTTAATTCGGTATCAAATGCTCAGGTTAGGGGAGATGCTTACGAAGGAGGTTGTATGGGTCCCAGAGGAGCCAGAATTTGGTTGTTTTTAGGTTTTGTAATGGGTTTTGCATCAGTCATAGCTGCATGCTGGATATTGTTTGCTGATTTTGTTGCAGAagtaAACACCCATCAGTGGCCAGGAGTTGCATTATTCTTACAGAattcattcattttcatttcatcTCTTCTGTATAAATTTGGAAGATCAGAAGATATGTGGggataa
Protein Sequence: MEISGNKYLHKKFKKQTSCNPVYNVEDKNDNSVLATASNTNNGERTSSNEEEPVNFLLFKDNKLVGSVPNYKSTNCDGSLVIESQDSERTVERSANTNVKLDNQSSISNVEVSVNIATNSSVTKEPVDCYNKYRTSDDQKIRSLEPQTISTSNVTSCISKLITTTTTSLLGNELKENSIRNFSFDTKVSISEPIPNIEKSSILDTVYSKSSLISERPNAAGIKLDVDESTHRVGRTDADSSNTSENILEKKNCTESTGGKYVCTYCNLACSKPSVLQKHIRAHTNERPYPCISCGFSFKTRSNLYKHCRSRTHANRVMGNKHVQAGQMETLDVDGSSEKSEDRLDCTEETEDNKNMSIMDDKPPKSMEINLDNAIQSNPDVVITPDQRNVWEQKSKPYKPRFHTAKLFFEENKLKENDAKLDNVSNLPQIHIKSPRKSPNPEIMKNRVELHEPQIIRTNPDLLKLRINELINKNNSIVNCDDAVVIRRRNMENIIENNNEYFPSHHVQWHHQPAEYRNTIDEPLNLTAKNRKRCLSDSDNTNKSLIKELLLKNLSSDPNLQCPYCKMIFQTVTELEMHKIKYCNAKHSNIRYARSSSVNVASILTQNKNAFDNIPHMQHTTFPLKSPGPCLGKTRLIDSEKPGEKYRTFSFDDNVIMHHSQSDSPSFNKYMLQSPVGSYPLSPQIKKNPIKLFGGEVKITQTSGETRSFKIESESINKMEEPHHFMEFSGNLSENLVIKSTLQSGGTVLQNKANYSPKMDSLPSPNIIRVYENAEMSPSNLNLPILNDKSKFTYDKISQPNIRQNDKLLIVANNEMLMKRRFPVRDKMEQNYTDNSVRNTDIKSDSEKDKEIYKSNLMDFGQKAVKLLAPNLKPPNLTIPGLPIPSAPGDNLMSSPIVTIAPLEINTSLMDNIIDRQHQENLNFAKKQISLQQRMAEVSQPQTVFNPMNIVVNGKVIRYVPGMPGPVVADTPAEMAFNPANTRLTPTSKLPKSPRPFDDPREVKEKVETPTSMLPVLNGVQFERKTPTIIVDQHDNKPPEPKLLIQNRERINLVSRVSESKVSPTATVSSPEKTSKEESRKFVRPTSLALKPNSVAFKNHHGLTPTMFNQALISPDTPRVAKKYCQQYLNGNYFSYLGLKSSTKSVYCTLNKTQPFYVKHFKKLSMYSEWRQQESKIDSLSVSAYDSRQRQQKYTMSGHAQANLVAHSSYKFVKTETPTSKEEKENKNSSVLGGYESNEDYTYIRGRGRGRYVCDQCGIRCKKPSMLKKHIRTHSDDRPYTCEHCNFSFKTKGNLTKHMKSKAHSKKYAATSSTSTQNSVTSSESEDSDAESSDESTRLQEHEAAHCLLSLSQKNTQPVSSITQESNSSSTSPFSSSSTTVSFSLTEFPNFLKDDKFLKNPDQINQVANTNFAKNKILDENPVNFNATKHLTEVFDVPTTSSQDSSNVSQYLGKSSTIRPLTYPYQQTQFDLDKDKSKNSENLDHIPKIITSAQQEMHQRLIKPVENKFIISNSRESISQEQKYPEIKFKRMDEVKQTVSSSQMSLPIIRQDFSPQNVEGNLPANIVFRKRKLSTSSNVQYKVQRSDVEPSSKAVDLSMPIIQDSPILDLSPAAVNGEPISFNGAFISSNNNDSLNNKLSASISKRTLILNHENHINPPRTVDVISDPQIMYNVVNSERVSEPLIVYNQIQKPRHNSFSESNSSETFSQSSDTNDRVIGKMVDIPENSMPSDKIEMYKSSVQVDIARSQSKTPDYGEQDQSAMQTLAEIAIKQVKLEKNILAKNVASEYLKLALNNEGSNQDGNMKKFASSTKEPVNELMVKPEESKNCSICSKNFSKPSQLRLHMNIHYLERPFRCESCSVSFRTRGHLQKHERSASHHNKLSSSPALSSQEPRPFKCSDCNIAFRIHGHLAKHLRSKMHIMKLECLAKIPFGLYAELERANSLLTEINTTDGDLCLESLKILARKLFSNDPSKLDQLDAATVYPNLMSGAYHVCGIFGTLSLVMVNSVSNAQVRGDAYEGGCMGPRGARIWLFLGFVMGFASVIAACWILFADFVAEVNTHQWPGVALFLQNSFIFISSLLYKFGRSEDMWG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00029643;
90% Identity: iTF_01275690;
80% Identity: -