Pnob041085.1
Basic Information
- Insect
- Poecilobothrus nobilitatus
- Gene Symbol
- ZNF219_1
- Assembly
- GCA_947095535.1
- Location
- OX352773.1:45691457-45695187[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.13 22 7.6 0.7 3 23 330 352 328 352 0.91 2 13 1.2 2e+02 4.6 0.2 2 23 419 439 418 439 0.94 3 13 0.0073 1.2 11.6 0.2 2 19 549 566 548 569 0.93 4 13 2.4 3.9e+02 3.7 0.3 1 23 586 609 586 609 0.92 5 13 0.81 1.3e+02 5.2 1.5 1 23 614 638 614 638 0.91 6 13 0.0035 0.57 12.6 0.8 2 23 654 676 654 676 0.96 7 13 0.00075 0.12 14.7 0.1 1 21 681 701 681 702 0.97 8 13 0.15 24 7.5 1.0 3 23 834 853 832 853 0.96 9 13 6.3e-06 0.001 21.3 1.3 1 23 859 882 859 882 0.96 10 13 0.00011 0.018 17.3 1.5 1 23 902 924 902 924 0.99 11 13 0.27 44 6.7 0.5 1 23 961 985 961 985 0.85 12 13 0.36 59 6.3 2.2 1 23 992 1016 992 1016 0.92 13 13 0.00075 0.12 14.7 1.6 2 21 1023 1042 1022 1043 0.94
Sequence Information
- Coding Sequence
- ATGCTAGAAGAAGATATAGATGATACCCATTTATGTATCAAATGCAGTACAACAATTGTAGGTTTAGATAATTATGTTCAACATCGTAAAAATCACTGTTCAGTTAAAAGAAATTCATCCCGTATTGCTCATCAAGTTCAACACGATGACCACGATCATCATCATCATCACCATCACGGATCACATTATGAAGGTTTTGATTTTAGTGAAGCTCAGGCTTCCAACTTTTCAAAAGACCATAATGAAGAAAACGAAAAAGCAAATAAATCAATGTCAGAAAGTTATGATTTACCATACGATTTAGGTGCTGATATATTCTTTCAGTCTCTAGAATTGCAAAGTAGTTCTAAACGTGGTCATCTTAATCATGCTGCTCCAACAGCAACAACAATTTCATCAACAATTACAAGAAGTTCTACAAATTTAAATTCTTCATTAACGACAGGTAGTAAAGTTTCGAGTCCAAGTAGTAAGGCTAATAATAGAAAAACTGGAACAATACAAGTGTTAAATCATAGTGATGAATGGATTCATCCAACAACTTCAAATAATTCAGATAACTTAATGAAAGCTGTACACGATATAAGTGGAACAAAAAAATGTGATTCAATATTTAAATTGATACCATTTCAACAAGATTCTCCTGATCAAAGTGATGACGGACATGGTGAAGATGATGATGATTTAGAAGAAGAAGATGATGAAGAATCAGATGACGAAGAAGAAGATTATTTAACTGTGCCGGCAAGTCATACAGGTGGAAAATGGAAACCAGAAAATAGTTTAAGAAATAGTCCAGGATGGGATAATGATCATCATTGGTCAGAATATAAATCAAATAATAAAGAAATAGATGATATAGAAAATGATTTAATAAATCCACCTCCTGGACATACAAAAGGTAAATGGGTTCCTGGTACAAAAGTTGTGAAATTAAATTATAAAGAAGATATAGAAATTGAAAAAATTTTTACACATCAATATTGGTGCAATACATGCAATCGAAAATTAGCTTCGAAAATTCTATATGAAAGACATTTGAAATCAAATTTACATATAAAAAGAGCTAAACCTGAAGAAGAACTTGAAAAAGTAGCTGTTCAAACAATGTCCGAACGTTTGAAAAAACCTTCAATTTATTTAAATTCTTCAATATATACAACAGAACTTGAATCACCAGCTCTCGTGCAAGAAAATTCTAGTAAAATTAGTCCAGTAAAAATAAATAAACGTAAACGGAGAAAACATTTCATTAAATGTGAAATTTGTAATACTCGTCTTCCAAAATATTTACTTGGAAAGCATTTAATCTCTCATTATCATTATCGACGAATGAATATTGATCCAAAAATTTCATTTGATATGATTTTAGAAAATATTCAAAGAATTGTACATCAATCACCATTTCAATGTCAACCATGCCGTTTTTATTGTAATACTGAAGATGATTTTATATTTCATTGGAATTCTAATGCTCATTTAGATTTAACTGAAGGTCCCGGAAAATGTTGGTGTACATTTTGTAAATTTGAATGTGAAGATAATAATCAAATGCGTCGCCATTTATTAAGTTCAGATCACAAAGAAGTTATTTTAGCTATTAATCGTTCAGTACCAATTATAATAAGAAAGAAAATTATTATTGAATGTACAAAATGTAAACAAAACTTTCGTTATAATATAGAATTACGAAAACATGCTGAATTATGTTCAACAGAACCTTTAGGCACAGCTTCAAATGATTATCAATCGAAATTTATATGTGAAAAATGTGGTGATGTAATGAAATCAGAATTAGCATTACAAAAACATGAAAAAAATAAACATTCAAGTAAATTTTATTTTTGTTCAATTTGTAAAATAAGACTGAAAACTCCTAAAGAATCAATAAAACATCGAAGAATGTCGAAACATAAAATTATGGTGAAAAAAATGAAAAATAAAGAAAATATGAATAGAAAATGTAGATCGTGTTCTGAAATATTTTCCGACTTAAATGATCTTAAAAAACATATTATTAAATCACATTCAGATGAAATGTTTTCATGTTCATATTGTGGTGAAAAATTTGCAATATCACAAGAACTAGGTCGTCATATGAGAGATAAAATATGTCAAAATAAACATTGTAATTTACAATTAGAAAATAAATTAGATAATGAAAACCAGATATTACCAAGCCATTTGAAAATTGTTAAAACTTCTGAAAATTTTCATCAAAATGAAACTAATGAAGAAACACTACGGGAAATTTCTCAGAAAAAGGAAAATAACGACAATGAAACCTTAAATATAATAAAAAAAATTGATGAAGACTCTAATCATTCAAAAAATTTAGAAAATGAAGCATTACAAGTAGAACCAGCAGAAAAAGAAGAAGCAACAACTAATCGTGTATGTGAATTTTGTAATTTTAAAACACCATCAACAGCAGAATTTATTTTTCATGAGTTATTACATAATTTACCATCAGATTTAAATAATAAAGAAAAAATAAATTGTCCAATGTGCTCAAAAGCTTTAGTTAAACATTCTTTAAGATTACATTTACGTTTACATACAAATGAAAGAATTTTCGAATGTCCTCATTGTAAATTGGGTTTTGTACGAAAATATAATTTAAAGGAGCATATTAATAATATTCATTTAAAAGTTAAAATACAATCTAATTCAACAAATGATATCACCAAGTCAAGAAAAGAATATGAATGTGGAATTTGTTATAAAATTTTCAGTAAATTAACTACATATAATCGACATTTAAATACACACAAAGAACCAGATAAACGTCTTCAATGCACATTTCCAAATTGTATATTTATAGCTAGAAATCTATATAATTTAAATGTTCATAAAACAACGCATACAAATCAAAAAATTTACGCATGTGAATTTGAAGGATGTATATATAAAGGAACTAATTTACAAAATTTAAAAAAACACCAAAGAAATCATTTAAATTTGGAAAAAAAGTATTTATGTGATTTTATTGGATGCAGTTTTAAAACAAAACATGCACCACATTTAAAACGTCATTTAGTAATTCATTCTGGTGAAAAAACACAAAAATGTCCATATTGTAATTTTACATGCAATAATGAAACAAATTTAAGAAAACATATTTTAGAAACAAAAAAACATCGAGGATTATTTTTATTTGAATGTAAATTATGTGAACAAACTGGTGAAAAACAATTTAAAACAAATTTTAAAAAAGATTATCGTACTCATTTAGTATTAATTCATAAAACTGATAAAGATTTGAATGCATATTTTAAATATCAAACATACCAACAGAATTCCGTACTAAAAAAAGAAAATTAA
- Protein Sequence
- MLEEDIDDTHLCIKCSTTIVGLDNYVQHRKNHCSVKRNSSRIAHQVQHDDHDHHHHHHHGSHYEGFDFSEAQASNFSKDHNEENEKANKSMSESYDLPYDLGADIFFQSLELQSSSKRGHLNHAAPTATTISSTITRSSTNLNSSLTTGSKVSSPSSKANNRKTGTIQVLNHSDEWIHPTTSNNSDNLMKAVHDISGTKKCDSIFKLIPFQQDSPDQSDDGHGEDDDDLEEEDDEESDDEEEDYLTVPASHTGGKWKPENSLRNSPGWDNDHHWSEYKSNNKEIDDIENDLINPPPGHTKGKWVPGTKVVKLNYKEDIEIEKIFTHQYWCNTCNRKLASKILYERHLKSNLHIKRAKPEEELEKVAVQTMSERLKKPSIYLNSSIYTTELESPALVQENSSKISPVKINKRKRRKHFIKCEICNTRLPKYLLGKHLISHYHYRRMNIDPKISFDMILENIQRIVHQSPFQCQPCRFYCNTEDDFIFHWNSNAHLDLTEGPGKCWCTFCKFECEDNNQMRRHLLSSDHKEVILAINRSVPIIIRKKIIIECTKCKQNFRYNIELRKHAELCSTEPLGTASNDYQSKFICEKCGDVMKSELALQKHEKNKHSSKFYFCSICKIRLKTPKESIKHRRMSKHKIMVKKMKNKENMNRKCRSCSEIFSDLNDLKKHIIKSHSDEMFSCSYCGEKFAISQELGRHMRDKICQNKHCNLQLENKLDNENQILPSHLKIVKTSENFHQNETNEETLREISQKKENNDNETLNIIKKIDEDSNHSKNLENEALQVEPAEKEEATTNRVCEFCNFKTPSTAEFIFHELLHNLPSDLNNKEKINCPMCSKALVKHSLRLHLRLHTNERIFECPHCKLGFVRKYNLKEHINNIHLKVKIQSNSTNDITKSRKEYECGICYKIFSKLTTYNRHLNTHKEPDKRLQCTFPNCIFIARNLYNLNVHKTTHTNQKIYACEFEGCIYKGTNLQNLKKHQRNHLNLEKKYLCDFIGCSFKTKHAPHLKRHLVIHSGEKTQKCPYCNFTCNNETNLRKHILETKKHRGLFLFECKLCEQTGEKQFKTNFKKDYRTHLVLIHKTDKDLNAYFKYQTYQQNSVLKKEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -