Basic Information

Insect: Plutella xylostella
Gene Symbol: topi
Assembly: GCA_905116875.1
Location: CAJHNJ020000490.1:9700681-9711039[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2 1.5e+02 3.8 4.0 1 23 136 158 136 158 0.96

2 18 0.036 2.8 9.3 0.5 1 20 223 242 223 244 0.93

3 18 0.15 12 7.3 0.1 2 21 292 311 291 311 0.95

4 18 0.032 2.5 9.4 1.4 2 23 372 394 371 394 0.94

5 18 0.54 41 5.6 0.1 3 21 433 451 431 452 0.91

6 18 1.2 95 4.4 0.5 2 23 458 480 457 480 0.92

7 18 3.4 2.6e+02 3.0 0.8 1 23 488 511 488 511 0.93

8 18 0.12 8.9 7.7 0.2 2 23 889 910 888 910 0.95

9 18 0.15 11 7.3 0.4 2 23 916 937 915 937 0.96

10 18 0.42 32 5.9 0.2 1 23 960 981 960 981 0.96

11 18 0.0048 0.37 12.0 0.5 5 23 1049 1067 1046 1067 0.92

12 18 0.0064 0.48 11.6 1.8 3 23 1085 1105 1083 1105 0.96

13 18 7.9e-06 0.0006 20.8 1.8 1 23 1111 1133 1111 1133 0.98

14 18 0.0015 0.12 13.6 2.5 3 23 1140 1160 1138 1160 0.96

15 18 2.3e-05 0.0017 19.3 2.4 2 23 1167 1189 1166 1189 0.96

16 18 2.2 1.7e+02 3.7 0.1 1 19 1196 1214 1196 1219 0.79

17 18 0.0025 0.19 12.9 1.2 1 23 1226 1249 1226 1249 0.95

18 18 0.0071 0.54 11.5 0.2 2 23 1285 1307 1284 1307 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2	1.5e+02	3.8	4.0	1	23	136	158	136	158	0.96
2	18	0.036	2.8	9.3	0.5	1	20	223	242	223	244	0.93
3	18	0.15	12	7.3	0.1	2	21	292	311	291	311	0.95
4	18	0.032	2.5	9.4	1.4	2	23	372	394	371	394	0.94
5	18	0.54	41	5.6	0.1	3	21	433	451	431	452	0.91
6	18	1.2	95	4.4	0.5	2	23	458	480	457	480	0.92
7	18	3.4	2.6e+02	3.0	0.8	1	23	488	511	488	511	0.93
8	18	0.12	8.9	7.7	0.2	2	23	889	910	888	910	0.95
9	18	0.15	11	7.3	0.4	2	23	916	937	915	937	0.96
10	18	0.42	32	5.9	0.2	1	23	960	981	960	981	0.96
11	18	0.0048	0.37	12.0	0.5	5	23	1049	1067	1046	1067	0.92
12	18	0.0064	0.48	11.6	1.8	3	23	1085	1105	1083	1105	0.96
13	18	7.9e-06	0.0006	20.8	1.8	1	23	1111	1133	1111	1133	0.98
14	18	0.0015	0.12	13.6	2.5	3	23	1140	1160	1138	1160	0.96
15	18	2.3e-05	0.0017	19.3	2.4	2	23	1167	1189	1166	1189	0.96
16	18	2.2	1.7e+02	3.7	0.1	1	19	1196	1214	1196	1219	0.79
17	18	0.0025	0.19	12.9	1.2	1	23	1226	1249	1226	1249	0.95
18	18	0.0071	0.54	11.5	0.2	2	23	1285	1307	1284	1307	0.94

Sequence Information

Coding Sequence: ATGTCTTCAAGTGATAAAAAGAGATCAAGAAAATCTAAGTTGGTGCCCCGAACTTTTGTGGAAGTGGAGAATGACGGAATCGAGGTTGTGCAGGCCCAGAAGACGGCAGCAGCAGTGGCCTTTGAAGTGGATGTGAAGGTGGAGTCCGGAGATGATGATGACGATGACTGGTGCAAAAAGCTTGAGGAGGAGGCGACGGCGGGCCGCGCGGGCGACGATGCCCCTCCCCCGGAAACACCTGTCAGTGCCGAGGACACACATCCTCTCGACCACTTCAGGGAGAACCACCCCAACGTCTCCACCTCGCTGGTGCAGTTCTGGTGCATCAAGCTAGAGAGACTCATCGCTGACTGCCACGTCGCCATCCACACCTTCCAAGTCTGCAAGAAGAGAAACGAAGTCCTCTACTACTGTGACACATGCTCAAGATACTTCGACGTGCAGCTTAGTTTCAAACAACACTTCTTTAAGCACAAAAAGGTTTCCACCTACCGAGTGATACCGCAGGTCACCACGCGCCAGCTCGTGCTCACGGCCGTCGAGGAGAACAAAGATGAAGATGAAGACGACATCAAACGAAGAATGTATCTCGATTTCATAACGACCGCCGTGGGCGCTGTTGGTAAAAATGAATGTTGGACGTATCAACCACTCAAGATCCATTATTACAAATGCTATGTTTGTTCCAAAAGCTTCGAGCATCTGCGGCCGTTCATCGAGCATTTGCTGGCTTATTATGGACATGAAAATACAGTTTTCGCAGTTGAAAGAATCCTCCAAAGCAACCTGTTCTATGTGAAGGCGAAACTACCGCACCAAAAAGAAACACAAGAGAACTTCCCTCTCTACTCCGCCAACTTTGCACGGCTAATGAAGTGCCTTATGTGCAGAGAAGGATTCGAAAGCCAAGCCGCATTGGATAAGCATCAGAATCCTATTAAAGTGGACCCGCTGCAGGTCGGGCCAGTGGTGAACGGGGACTGCGTTTACGAAGCCCTAGCGATCCGGAGGACAACCGAAGCTAGATTTACATGCGGTTGTGGACAGTTACTGATGGAGAGCCTTATAGAGGAGCACAGAGCGGTGTGTAATCTGGGGGCGTCGTTGCCGCTAGTGTGCTGCGTGTGCAAGTACACAACGAAGAAGCCGGGGGAGCTGCGGCTGCACCAGATGGAGCGGCATACTGTACGCTCGGACGAGTTCCTGCTGCAGCGGCTGACGCAGTGTGGCTGCCTGGCGCGCTACTGCGGCAAGCGCGCCAGCCACCACTGCCCGCTGCGCAAAGACTGCGTGGCCTGCAAGGACTGCGAGCTCACGTTCCAGAACGAGCTGTTTCTGAGAGTGCACAGAATGGCGACCCAGTTCGGGCAACGCTGCGAGCTATGCGGCGTGTTCCTGCCGCGCTCGTGCATGCTCGCGGAACACCGGGCGCTGCGGCACGACGGCGGCGCGCTGCCCGCGTACAGCTGCCCGCGCTGCCGCCACACATACCTCGACCGGGAGGTGCTGTACGAGCACATAAACCAGGCACACAAGAGTATGAAGCCGAGGTATTATAAGAGTCTTGTCCCTTGGAAGAGAGTCGTGATTAAAGATTTAAATAGCCCCGTGGAGATACTGAGCGATAGTGAATACCCGGCTCCGTGGAGTTTCATCCCAAGCCTGTTCCCCGAAGCCATGACGTCGCTCGTAGCTGACGATGATGACGCTGACAGCACCACACGTGTACGAGGCATCACTGAACTAGTCAGGAAGTTAAACAAAATTAAAAAGGAAAACTCTGTTCCCACCGATAATGTTCCTCAAGACAGAAATGATGTCTGGAAATCTATGCTTAAACTGAAAGCTAAAAATACAGAAGTGCCGAAAGTTACGATCCACATACCAGGCATATCTGAATTAGTGAAGAAGTTGAAGAAACGAAAACATGAATTAATATCTGAAACCACGGATGGTCAAGACAGAGCTAAAACTAATACACCTGACAAAGACATTGATGACAGTGTTAATGAAGAAAGTAGTATTGTAATTGCTAAACCAGAAACAGATCACGATTATTTTAAAGTCCAGATCAAGGAGGAAAATATTGAAACAGATAGTACAAATGTTGATGCATTTAAAAATAGAGATGAAAAAGTACCTATGGAAATAATCGAAAATATCGTTTCAAAAGATAATGAGGCGGAGAACAGAAAAGCAAGTGAAGTTGAGCCTGATAAAATCGCCGTGAAACAGGAAAGCGATGATAGTGCTGTGCCTTTTGAATTAGCTAGGGTAAAAACAGAACTAATTGAAATGGAAATAGACGAACAAACCCCTTCAGAAGAATTTTTAGTTAATTTAAAATCCGAAGTAGAACAAGACACAGGATTATCCAACGTATTCCAGCCATCTGAGAAATTTAGATACACCAAGACTGCCAAACCCCAAGAACCAGAAACCATAAGAATCAAAGCCGAACCCGTAGACCTAGAAGAAGAGAGGATTATCTTACAAGAGCTCGAGTACGACGACACCGCCGAGTCTATAGACGACTTCATACAGAACAACTCCGAGATCACAACGATGGAGATCAAGCCGGAGATCTACTACGAGAGCGACGACAGCCCCACGAAGACGCAGACGAAGCGATACCCGCGCGTGCCGGTCGAGCCGCTGGTGCTGACCTGCTCCAAGTGCGGGGCCACCTTCATGGAGCTCAAGCTGTATCTCAACCACACGGCCGTGCACGGGAACCCCAAGCTGTCCTGCCCGGACTGCCACCAGCCCATGGACACCATGAGCAAATTGCGCATGCATGTCCTAGTCCATGTCAGGAGGAACTACGTCCCCGTCTACACAATACACCACGAGGACGACTCGGACTCCAAACTGACGTTCAGCTGCAACAAGTGTGGCGGCGTCGTGGATAAGGAATACTTCTGGTCGCACTGGGAGACTCATCTGGTCTTTGGAGAGGTTAAAAAGCCAGTTAAAGCCGCTACAGCGGAGCCAGAAGAAAATGAAGAAGAGGAGGAGGATGATGGCTTGAAAGCGTACCCGGGGGACAATCAACCGGGGGTCGACCTTCTACCGGATGTGATGACTCTACTCATTAATTTGCTCCAGTCGATTACGGGAACTATGAATGAAAAGTTCTGCATAGTCTGTGAGAAGTTTTTCATGAGAAATTATGATCTCAAAAGGCATATTATAGAGCACATGTTGAAGGATGCGAGGGCGAATTGGCCGAAAAACGGAAAGGCTCTCGCGTGTCAAATATGTAATGCTAAATATAAGAAGTCTCACCTGTACAAGTTGCACATGCGGGGCCACGGCAAGCTGCCGATATACAAGTGTGAAATGTGCACGAAAAGTTTTGGCGATTCGAGCAATTTCGCCAAACATAAGAAGATACACGGGCTGCAGACGATGCACTGTGACATGTGCAGTCGCAAGTACAGGAGCAAGGAAATGCTCATCAAACACATCGAGCGGCACGCGCGCCAAGCCCCGCAGAAGTGTAAACTCTGCGATAGATCGTTCTCGTTCGCCAACGAACTCAAGAAACACATGAAGTTGAAACACGTGACGGGCTCCAAGAGCTACGCGTGCGGGATCTGCGGCGAACGATACCCGAGCATCAAGGAGAAGTGGGACCACGAGTTCGCGGTGCACGGCGAGACCAAGCGCCAGTTCAACTGCGAGTATTGCCCAGAAAAGTTCCGACTACAAAGACTATACAAACAACATCTCAACCAAGCACACAAAAAGGCGTTGGTGATACCGGCAAAAACGAACAACAGGTCGCTGTTGCGTCGCAATGCAGTCATACAAAATGTTGCTATGCCTCCTGGGCCGCTATTTTATATCAAGTGTCCGTTTTGTGAGGAGATTTTCAAGCAGAAAGCGGAGTATTATATTCATGTGACGCGTGTTCACGAGGCGCAGCCCACGGAGGTAAAACAGACGGGTGGCGTGGAGGCGCAAGTGGACTCGGATGATGATAGATTGAGTATTGATATGGATAAAGTGAAACAGGAGGCGTCGAGTGAATCTGAAAATGAAGAGTTACGTAGGGCTGTCAGGCTAATAATGTGA
Protein Sequence: MSSSDKKRSRKSKLVPRTFVEVENDGIEVVQAQKTAAAVAFEVDVKVESGDDDDDDWCKKLEEEATAGRAGDDAPPPETPVSAEDTHPLDHFRENHPNVSTSLVQFWCIKLERLIADCHVAIHTFQVCKKRNEVLYYCDTCSRYFDVQLSFKQHFFKHKKVSTYRVIPQVTTRQLVLTAVEENKDEDEDDIKRRMYLDFITTAVGAVGKNECWTYQPLKIHYYKCYVCSKSFEHLRPFIEHLLAYYGHENTVFAVERILQSNLFYVKAKLPHQKETQENFPLYSANFARLMKCLMCREGFESQAALDKHQNPIKVDPLQVGPVVNGDCVYEALAIRRTTEARFTCGCGQLLMESLIEEHRAVCNLGASLPLVCCVCKYTTKKPGELRLHQMERHTVRSDEFLLQRLTQCGCLARYCGKRASHHCPLRKDCVACKDCELTFQNELFLRVHRMATQFGQRCELCGVFLPRSCMLAEHRALRHDGGALPAYSCPRCRHTYLDREVLYEHINQAHKSMKPRYYKSLVPWKRVVIKDLNSPVEILSDSEYPAPWSFIPSLFPEAMTSLVADDDDADSTTRVRGITELVRKLNKIKKENSVPTDNVPQDRNDVWKSMLKLKAKNTEVPKVTIHIPGISELVKKLKKRKHELISETTDGQDRAKTNTPDKDIDDSVNEESSIVIAKPETDHDYFKVQIKEENIETDSTNVDAFKNRDEKVPMEIIENIVSKDNEAENRKASEVEPDKIAVKQESDDSAVPFELARVKTELIEMEIDEQTPSEEFLVNLKSEVEQDTGLSNVFQPSEKFRYTKTAKPQEPETIRIKAEPVDLEEERIILQELEYDDTAESIDDFIQNNSEITTMEIKPEIYYESDDSPTKTQTKRYPRVPVEPLVLTCSKCGATFMELKLYLNHTAVHGNPKLSCPDCHQPMDTMSKLRMHVLVHVRRNYVPVYTIHHEDDSDSKLTFSCNKCGGVVDKEYFWSHWETHLVFGEVKKPVKAATAEPEENEEEEEDDGLKAYPGDNQPGVDLLPDVMTLLINLLQSITGTMNEKFCIVCEKFFMRNYDLKRHIIEHMLKDARANWPKNGKALACQICNAKYKKSHLYKLHMRGHGKLPIYKCEMCTKSFGDSSNFAKHKKIHGLQTMHCDMCSRKYRSKEMLIKHIERHARQAPQKCKLCDRSFSFANELKKHMKLKHVTGSKSYACGICGERYPSIKEKWDHEFAVHGETKRQFNCEYCPEKFRLQRLYKQHLNQAHKKALVIPAKTNNRSLLRRNAVIQNVAMPPGPLFYIKCPFCEEIFKQKAEYYIHVTRVHEAQPTEVKQTGGVEAQVDSDDDRLSIDMDKVKQEASSESENEELRRAVRLIM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -