Basic Information

Gene Symbol
-
Assembly
GCA_027563975.2
Location
CM050492.1:673674-674750[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 6.4 3.7e+02 2.2 0.1 2 23 28 49 27 49 0.79
2 10 0.0098 0.57 11.0 0.2 2 23 74 96 73 96 0.92
3 10 0.00059 0.034 14.9 0.3 2 23 119 140 118 140 0.96
4 10 0.00018 0.01 16.5 2.8 2 23 145 167 144 167 0.95
5 10 0.041 2.4 9.1 0.1 3 20 176 193 175 195 0.92
6 10 4.2 2.4e+02 2.7 0.7 1 23 202 225 202 225 0.88
7 10 1.6e-05 0.00096 19.8 0.4 1 23 232 255 232 255 0.97
8 10 0.00099 0.057 14.2 0.2 5 23 263 281 261 281 0.95
9 10 4.1e-06 0.00024 21.6 0.4 1 20 287 306 287 309 0.94
10 10 2.7e-06 0.00016 22.2 1.9 1 23 315 338 315 338 0.97

Sequence Information

Coding Sequence
ATGGCGATGGCGCGCCGGAATGCCCAGATCATAGTGGAGTATACCACAGCTTACCCCTTCAGGCTGCCTGAGTGTTCGTTGGTGTGCGTGTACTGCGAAGAGAGCGTAGCGACCACACAGTTCCAAACGCACATGGGATCTCAGCACCCAGAAGCCAAAGTCAAAATAGCGTTCGCTCATTTGAACGACGGCTACATCAAAGCTGATTGCACAGATTTAAAATGCAGAACTTGTTCAAAAATGTTCGAAACGCTTGAAAATATCGCAGATCATCTTGTGTCAGCACACAAATTGCCTTTACATCTAAATTTCGATTTGGGAGTACAACCGTTTAAGTTCGGAACTGACCAGCTAATATGCGCAATGTGTCCAATGAAATTCGCGACGCTTCGATCGTTGAGTAGACACACGCAATCTCATTTTAGAAAGTGCACGTGTGAGCTTTGTGGCAAGTCTTATTTATCGTCATCCTCTTTACTACATCACATGAAAGTTATTCATACAAAAGATAGCGAGCAAAGGATATGCGAGAAATGTAAACGCGTTTTTGATTCGCTCGAAGCTAGGAGGAAACATGTTATAGAAACTCCTGAGTGCTGGCGATATTCGTGCAGACGCTGTTTCGAAAAATTTTTGTCGGCATCATTAAGAGACGCACACCAAAAAGAAGTTCACGGAATCGATAAGCGATCGTACTCGTGCCCGGAATGTAAAAAAGTTTTCCCTGACTTAACTAAATATAcagtacattataaaattgaccACACTGACAAATTTTTCCCGTGCGATTGCGGTCGCAAGTTTGTCTCCAAATATTTGTTGGAAAGCCACCGCGTTATGCACACAAAAGAAAGATCCTTTTCGTGTCCGGAATGTTCTAAGACGTTTCCGAGGAAACGCACCCTGATTAATCATATGTGGATTCACAGCGCGAACAAGAGATTTGAATGCGATCTGTGTAATAAGTCGTTCAATCAGAAAGTCAGTTGGAAAACGCATATGAAGTCTTACCATCCTGAGTCGATGGTTACAACAACAATATCATCAAGGTCAAACCTTTTAGCCTTCGATGTCTAA
Protein Sequence
MAMARRNAQIIVEYTTAYPFRLPECSLVCVYCEESVATTQFQTHMGSQHPEAKVKIAFAHLNDGYIKADCTDLKCRTCSKMFETLENIADHLVSAHKLPLHLNFDLGVQPFKFGTDQLICAMCPMKFATLRSLSRHTQSHFRKCTCELCGKSYLSSSSLLHHMKVIHTKDSEQRICEKCKRVFDSLEARRKHVIETPECWRYSCRRCFEKFLSASLRDAHQKEVHGIDKRSYSCPECKKVFPDLTKYTVHYKIDHTDKFFPCDCGRKFVSKYLLESHRVMHTKERSFSCPECSKTFPRKRTLINHMWIHSANKRFECDLCNKSFNQKVSWKTHMKSYHPESMVTTTISSRSNLLAFDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01220969;
90% Identity
-
80% Identity
-