Basic Information

Gene Symbol
MAZ
Assembly
GCA_963576535.1
Location
OY754922.1:8427770-8447004[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.32 21 6.3 0.6 3 23 433 454 431 454 0.90
2 10 1.4 92 4.3 2.0 1 23 458 480 458 480 0.96
3 10 2e-06 0.00013 22.7 1.6 1 23 485 508 485 508 0.98
4 10 0.02 1.3 10.1 0.6 3 23 514 535 513 535 0.93
5 10 0.0017 0.11 13.4 0.1 2 23 550 572 550 572 0.95
6 10 0.087 5.7 8.1 0.4 1 22 584 605 584 608 0.90
7 10 7.5e-05 0.0049 17.7 2.0 1 23 667 689 667 689 0.95
8 10 0.0025 0.16 12.9 1.2 1 23 695 717 695 717 0.99
9 10 2.6e-06 0.00017 22.3 1.4 1 23 731 753 731 753 0.97
10 10 3.7e-05 0.0024 18.7 0.5 1 23 759 782 759 782 0.97

Sequence Information

Coding Sequence
ATGCCACCGAAAAAGGCGAAAAAtagattcataacgtgcgaaatatGTGGAGATCGATCGAGCCGTAGTATTTTGGAAAAGAGGAAGTTTATGGCAAAATTTCCTTTGGATGAGACTCGATGCAAGGAGTGGGTTAAGGTTGTGGGAAAAGAGGATCTGATATATGTTCCCATTGAAAAACTTCATGAATTAAAATATGTATGTGGGTCCCACTTCGATGACAGATccttcacaagaaaaaaaagtcGCCTTAAGAGATCTGCCATaccaacaaaaaatttaaaagttccACTCACTGATGCAGCTTTACTAGAATTTCCGCTCCATATTCAAGATACTACAGATTTTCAAGGTATAAGTGACATTGAAACTTCAGTATCCCAGGTGGAAGAAGCAATCCCTGGGCGTAGTAACTCTGGTACCTTAATGGAACTATCAGTGGAATCCTTTGATGATGGCATTGCCCCAGAATCACCCGCTTATCCGGCATCTAACAAAGCTGCCTCACCAACACCTTTACACCCCGGCATCGTCACACCGGCTCCAAGTGATTCTGCGGCTCTAACAACACCTCCTGAGCCAGAGGAATCCTTTGAAGATGGCATTGACTCAGAATCATCCGCTTATCCAACACTTAACAAAGCAACTCCAACACCTTTGCAGTGCAACGTCACACCGGCTCCAAGTGATTCTGCAGCTCTAAATACACCTCCTGAGCCAGTGTGCAGAATATGTCTAAGCTCGGGTACTGTGATGGTAGCGGACATGGACTGCACTCTAGAGGTGTTCTATGATGAACTCATCTATCATGACACTTATGAGCATGAATTGCTGTCCTTCTGCCAGATATGTGAGTATCAGCTACGTCGGCTCTACAACTTCAGACAGAAATGCAAGCGAGCCCATATCCTGCTCAAAAACAAGGGCGCTGAACTCTTTGAACCGTGGGTTTTGTACGTTATGAAGCGTGGGGAGCTAGAAGGTATCGAGGATCTGGGAGTGAAGATCTGCGAGGAAGTAGTATTGAAGCTGTTAGACAAGTGTCCAATGGGGACTTTCATGCAATCTGGACTTTCTAAATCCTATTTTTCGGCAAACAGAGTTCCAAAAATGCGTCGCTTCCTCCAAAGTGTATTGCAGAGATACAATCCGTTGTACGAAGAGATGTTCGAGGTGACATATCTGAACACGCAGGAGAAGCAGCTGGAGGAGTTCCAGTCGAGACAGCACTCGCCGCAGTATACGGAGGCTGTCTTTAAATGCGGTATATGTTATCAGGAGAACAAGCCATTGGCGTGTTCGATATGCTCGATGCGGTTCTACGCTGAGAAGTCACTCAAGTCGCACTTCGTCAAGAGTCATAGGGACAAGTTCAGCTGTAAGCTGTGCCCTTTCGTCACTTACAACTACCTCACCATGAGAAATCATTTCCGAGATCACAAACGATTCGTGTACCAGTGCCCTGACTGCGATAAGAAATTTACCAAACGTACAAGCATGTTAAACCATGTCCGGACCATGCACCGCCTGGGCGGCATCTGCTCCGTGTGCGGGCGACGCCTGGCTTCACATGTCAAACTGAAGACGCACATTGCGCAACAACACAGCGATATCGCTCCCGAGGTGTTGGCGTCGACGCCAACAGAGCAGTGCGACAAATGTAAAGCTGCGTTCTACACGCAGGAAGCACTATTACGCCACGTCGCGGTCACGCACCGCCCTACCTACAATGAGGACCAGAATGTATCGTACCCGTGCTTCTATTGTAAGATAGACTTCGAGACGGTAGAAGCGCTGTACACGCACAAGAAAAGTGAGGAGCACCGGGACGCGATAAAACGCCTCGCGAGGAAGAAGACGTCTACCACTAGGAGGTCGCATAGAACGTGTCCACTTTGCAACGAGGAGGTGTTGAACGAGCATGTGCGCTCGCTGTACGAGCACTACCGCGCGGCGCACCCGGCCGCGCCGTACCACGCCGCGGCCGACGAGCGCGACTTCCTCTGCGAGCAGTGCGGCCAGACATTCACTTATAAACACATGTACGAGGAACATATGAACGTGCATACTGGCGCACAGCCTTACCAATGCAGCGAGTGTGGGGCTCGCTTCGCTCTTCGGTCGAAAGCACACATGCATCTACGCAGTCACAGACGGAAACTCCGTGGTGACTTGAAGAAGCGTACCAAGTTTGATTGCAACTTCTGCCCGAAAATCTTCAAAAACAAATTCTCCCTCGAGCGACACATTTTGACTCACACAGGCGAAAAACCTCACCAGTGTCCCATGTGCGACCAAAGATTCACACAAGCCAGCGCAATAAAACTTCACATCACCACGGTGCACTTGAAACTACCCGCACCATACGGCAGGCCCGGCGTTGAACGCGCCGAAGCCACTTCTTGGAAACCCCGTGCGGGTGTCTCGGTGCCTCCCATGAGCTTGGAACTTCTCCAGACATACGTCATTGGACCCTGGAAGAACGACCTTCCTAGGTTAAAGGCGATGCTGGACGCAAGTAAAGAAGACACGTTCGATGCAAATGAAGAGAAAATTGAAGATTCGTATGAGTACATGGACGCAAATAAAGAAGAAGACAAGTTTAGTGTAAACGAAGAGAAAAATGAAGATTCGTATGTGTTTATGGACGCTAAGACAGGAGAAATGGACTATATGGTTGGTGCCGAAGAAGAGGTGATAGAGGAGTCTTGTGATAGTGATTAG
Protein Sequence
MPPKKAKNRFITCEICGDRSSRSILEKRKFMAKFPLDETRCKEWVKVVGKEDLIYVPIEKLHELKYVCGSHFDDRSFTRKKSRLKRSAIPTKNLKVPLTDAALLEFPLHIQDTTDFQGISDIETSVSQVEEAIPGRSNSGTLMELSVESFDDGIAPESPAYPASNKAASPTPLHPGIVTPAPSDSAALTTPPEPEESFEDGIDSESSAYPTLNKATPTPLQCNVTPAPSDSAALNTPPEPVCRICLSSGTVMVADMDCTLEVFYDELIYHDTYEHELLSFCQICEYQLRRLYNFRQKCKRAHILLKNKGAELFEPWVLYVMKRGELEGIEDLGVKICEEVVLKLLDKCPMGTFMQSGLSKSYFSANRVPKMRRFLQSVLQRYNPLYEEMFEVTYLNTQEKQLEEFQSRQHSPQYTEAVFKCGICYQENKPLACSICSMRFYAEKSLKSHFVKSHRDKFSCKLCPFVTYNYLTMRNHFRDHKRFVYQCPDCDKKFTKRTSMLNHVRTMHRLGGICSVCGRRLASHVKLKTHIAQQHSDIAPEVLASTPTEQCDKCKAAFYTQEALLRHVAVTHRPTYNEDQNVSYPCFYCKIDFETVEALYTHKKSEEHRDAIKRLARKKTSTTRRSHRTCPLCNEEVLNEHVRSLYEHYRAAHPAAPYHAAADERDFLCEQCGQTFTYKHMYEEHMNVHTGAQPYQCSECGARFALRSKAHMHLRSHRRKLRGDLKKRTKFDCNFCPKIFKNKFSLERHILTHTGEKPHQCPMCDQRFTQASAIKLHITTVHLKLPAPYGRPGVERAEATSWKPRAGVSVPPMSLELLQTYVIGPWKNDLPRLKAMLDASKEDTFDANEEKIEDSYEYMDANKEEDKFSVNEEKNEDSYVFMDAKTGEMDYMVGAEEEVIEESCDSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01219852;
90% Identity
iTF_01219852;
80% Identity
iTF_01219852;