Prub009623.2
Basic Information
- Insect
- Plemyria rubiginata
- Gene Symbol
- zfh1
- Assembly
- GCA_963576535.1
- Location
- OY754915.1:204706-208192[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.019 1.2 10.2 0.2 1 23 50 72 50 72 0.95 2 8 4.5e-06 0.00029 21.6 3.0 1 23 83 105 83 105 0.98 3 8 1.9e-06 0.00013 22.7 6.2 1 23 114 136 114 136 0.99 4 8 0.00014 0.0089 16.9 1.0 1 21 142 162 142 163 0.95 5 8 0.014 0.93 10.6 0.2 2 21 429 448 428 449 0.92 6 8 1e-05 0.00067 20.5 1.1 1 23 744 766 744 766 0.94 7 8 0.00018 0.012 16.5 7.9 1 23 772 794 772 794 0.98 8 8 0.072 4.7 8.3 7.1 1 21 800 820 800 821 0.96
Sequence Information
- Coding Sequence
- ATGCCCAAGACGAaatgctacgccgtagacgcTCTGCTACGATATAAAACAGTCCGGCCGctggccggcggcggcggcggcggcgaggcCAAGCCGCCCGAGGAGGAGGAGGAGCGCAGCGGCTCCCCGCTCGGCCCCGGCGGGCCCTACTCCTGCGGCCAGTGCCGCGGGGCCTACCCCACGCGCGACCAGCTCGAGCGGCACGAGACCCTGCACTCGCCGAGCACACAGGTGGATACACTCAAATATACATGCAAGATCTGCCACAAGAGCTTCGCGAACGTGTATCGCCTGCAGAGACACATGATCAGCCACGACGAGAGTGCGCAGCTGCGTAAGTTCAAGTGCAACGATTGCGACAAAGCCTTCAAGTTCAAGCATCACCTCAAAGAACACCTTCGAATACACAGCGGAGAGAAACCTTTCGAGTGTGCCAACTGCGGGAAGAAATTCTCCCATTCCGGTTCCTATTCGAGTCACATGACCTCTAAGAAGTGTCTTGTGATGAACCTTAAAATGGGAAGAATAAAGCCTAATAACCCCGCCCTGAACCCTGACAGGAGTCCCTCCCGCAAGCGCGCCAACGCCTTGGTGGCGTCGCAAATGAATAACAACATTTCACCAAATGGAAACTCCTTCTTCCCCATTCTTCCTAAGTACAATGAAGCCGCAGCCTTCTTTGCTTCTATGTCTTCACAGGAAAACAGTTTCCACCGTCCGCCTCTGGGACAACCTGGCATGAATCCATTCTATATGCCTCCCGGAATGCCGATGAGTCCGGCGACTGGTATCACTCCCTACACCCTGCCAACATCACTCAGCCAATTATTCGAGCAATTAGCATCATCGCAATACCCTCAGAGGAAAATTGAAAATCATGCTAGTCCAAACCAAACTAGCCTACATCTTGCTGACCCCGAAGATATGATCGAAGAGGTCACGGAGGAGGACGACAAAAGGTCAGAAGGTAGCGCCGAGCTCGTTATGGATATAGAAGACGACGATACTATTAAAAAGGAGCACGATGCTCGGGAAACAGAAATGAAATCGCCACCTCACAATAACGAACCCGTTCCGTTGAATAATAATGGCAACGAAGTCGATAACAAACACTCCGGTTTCAATACAATACTCAAATCTGTGAGCGCCTCTGTAACGAAACATTTCTTTGGAGCCAACATGGAAACGCATTCTGCAATTTCTGGTAACGGTTATCCAAGCAGAGCGTCACCGCCAACTCCTCAAATAGTCATTAAGGAAGAGCCAGAAATTGAAGATCCACAGAGGTGTATGAAATGTAATGCTAATTTCGCGAACAAAAGTGATCTGTTGGACCATGAGAAAGTAGTTTGTAACAGTTTGTTCAGAAAGCACGAAAGTTTGGCAGCTCAGGTAGCCGAAACGGTAGCTCTTAACAGATTAGAAATGGAGATGGAAATGCGCACTTCAGCTCAGAGTGGAGTAAGTGCAAGTGAAGACGAAGATCGAGAAGACCGCGACGAAAAGGAGTCAATTCACGACAGTGACAGAAAGATCAGAGTTCGCACGGCACTAAGCGAAGAGCAACAGGTGGTGCTCAAAGAGCACTATTCGTCAAACTCGAGACCAAACCGGGAAGAATTCAAGAGAATAGCCCAACAGATTGGACTAGATAACAGAGTAGTACAAGTGTGGTTCCAAAATAACAGGGCTAGAGTTCGAAGAATGATTCAGTCGACCGCTGTGTCTGACCAGCCTCTAGACTTATCAACAAAGAAGTCGAACACATCGGTGACCTCCAGTCCATCGCCGTCTCCGTGCAGCATTTCAGTGACACATTCCGATTCGGAAGAAGCAGTAAACCTTAGCCAAAAATCATCTCGCAGCACGACACCGCTGCGACCAAACTACATGAACGCGTATCCACATTCCAATTGTTCCTCGTCGTCGTTCACTGACTTCCGGCTCTCACCGTCTCCAGGGGAAAACTTGAATGGCCTTAAACGGGTGCATCAAAAGCTAAACCCTACGATGCCGATGGATAAGCTGTTACACTACAACGACATAGTGAATGCACGCTCTCCAATCCTAAACATGCACCTATCGGCGGATATCAACCGGCACGGCTCGAGTCCATCGTACGAGCGCGCTTCCTGGGATGACATGCAACCCCCAAACGAATACGAAGACGATGCGACTGTACTTAAAAAGATTAAAATGAAAAGCGAGTTTAAGCAGGAAGAGGGCCAGTTTGTCTGCGACCAATGCGACAAGACCTTCGTCAAGCAGAGCTCGCTCGCCAGGCACAAATACGAACACTCAGGTCAGCGTCCTTACAAATGTGTGCAGTGTCCGAAAGCGTTCAAACACAAACACCACCTGACGGAGCACAAGCGGCTGCACACGGGCGAGAAGCCGTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCGCACTCGGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCCATCTGCAAGCCGTACCGGGACTAA
- Protein Sequence
- MPKTKCYAVDALLRYKTVRPLAGGGGGGEAKPPEEEEERSGSPLGPGGPYSCGQCRGAYPTRDQLERHETLHSPSTQVDTLKYTCKICHKSFANVYRLQRHMISHDESAQLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRANALVASQMNNNISPNGNSFFPILPKYNEAAAFFASMSSQENSFHRPPLGQPGMNPFYMPPGMPMSPATGITPYTLPTSLSQLFEQLASSQYPQRKIENHASPNQTSLHLADPEDMIEEVTEEDDKRSEGSAELVMDIEDDDTIKKEHDARETEMKSPPHNNEPVPLNNNGNEVDNKHSGFNTILKSVSASVTKHFFGANMETHSAISGNGYPSRASPPTPQIVIKEEPEIEDPQRCMKCNANFANKSDLLDHEKVVCNSLFRKHESLAAQVAETVALNRLEMEMEMRTSAQSGVSASEDEDREDRDEKESIHDSDRKIRVRTALSEEQQVVLKEHYSSNSRPNREEFKRIAQQIGLDNRVVQVWFQNNRARVRRMIQSTAVSDQPLDLSTKKSNTSVTSSPSPSPCSISVTHSDSEEAVNLSQKSSRSTTPLRPNYMNAYPHSNCSSSSFTDFRLSPSPGENLNGLKRVHQKLNPTMPMDKLLHYNDIVNARSPILNMHLSADINRHGSSPSYERASWDDMQPPNEYEDDATVLKKIKMKSEFKQEEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCVQCPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00698162;
- 90% Identity
- iTF_01219675;
- 80% Identity
- iTF_01219675;