Basic Information

Insect: Plectrocnemia conspersa
Gene Symbol: ZFHX3
Assembly: GCA_009617715.1
Location: VTFK01000003.1:3420042-3429480[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 4 3.5e+02 2.4 1.7 1 21 54 74 54 77 0.87

2 14 0.053 4.7 8.3 0.0 1 23 87 110 87 110 0.92

3 14 0.27 24 6.1 2.0 2 21 177 196 177 200 0.91

4 14 0.4 35 5.5 0.4 3 23 214 237 212 237 0.87

5 14 0.0089 0.78 10.7 1.7 1 23 255 277 255 277 0.97

6 14 0.0012 0.11 13.4 0.3 2 23 284 306 283 306 0.96

7 14 0.00051 0.045 14.6 3.9 1 23 414 438 414 438 0.92

8 14 0.0084 0.74 10.8 0.7 1 22 458 479 458 482 0.89

9 14 0.00084 0.074 14.0 0.2 1 23 532 556 532 556 0.93

10 14 0.34 29 5.8 2.6 2 19 734 751 733 756 0.91

11 14 2.2e-05 0.0019 19.0 2.9 1 23 1320 1342 1320 1342 0.99

12 14 0.00089 0.078 13.9 0.3 1 23 1428 1450 1428 1450 0.98

13 14 0.0071 0.62 11.0 0.4 2 23 1592 1614 1591 1614 0.96

14 14 0.23 20 6.3 2.6 3 22 1870 1889 1869 1892 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	4	3.5e+02	2.4	1.7	1	21	54	74	54	77	0.87
2	14	0.053	4.7	8.3	0.0	1	23	87	110	87	110	0.92
3	14	0.27	24	6.1	2.0	2	21	177	196	177	200	0.91
4	14	0.4	35	5.5	0.4	3	23	214	237	212	237	0.87
5	14	0.0089	0.78	10.7	1.7	1	23	255	277	255	277	0.97
6	14	0.0012	0.11	13.4	0.3	2	23	284	306	283	306	0.96
7	14	0.00051	0.045	14.6	3.9	1	23	414	438	414	438	0.92
8	14	0.0084	0.74	10.8	0.7	1	22	458	479	458	482	0.89
9	14	0.00084	0.074	14.0	0.2	1	23	532	556	532	556	0.93
10	14	0.34	29	5.8	2.6	2	19	734	751	733	756	0.91
11	14	2.2e-05	0.0019	19.0	2.9	1	23	1320	1342	1320	1342	0.99
12	14	0.00089	0.078	13.9	0.3	1	23	1428	1450	1428	1450	0.98
13	14	0.0071	0.62	11.0	0.4	2	23	1592	1614	1591	1614	0.96
14	14	0.23	20	6.3	2.6	3	22	1870	1889	1869	1892	0.89

Sequence Information

Coding Sequence: ATGCTGAAATTTTTGGAACAACAGCAGCATTTACATCAACAGATGCAACAGCAGATGCAGCAGCAACATCAGCAGCAGCAACAACACCTATCGCAGCAGCAGCAACAGCAGCAATCGCAACAGCAGCAGCAGTCGcaagaagaaaataatacagATCAACACTCTTGTCCTTTCTGTAATTTCACATGCGATTCTGAACTTCGTCTCCAAGCTCACGTCGTAGCTCAACATGGGGCGCCAACTCCTACTCCGCCAGCTTTCCTCTGTCCGCTCTGTCAAGACGGTTTCAGAGACAGGCCCGCATTAGAGCGACACGTGATGCAAATTCATTCGGTTAACTCTGAAGGATTGCAACGACTTCTTATGTTAGTGGACCAAAGCCATTGGCTGAACAGCACGAGACTCGTGAGCCCCGATTCAGTGGCGAGCAGTAAAGATTCTGCGCAGAAAAACGACTCCGCAAATCTCGAAGAGGAGAGAGAAATATCTTCACCGCACAGCGAAGAAAACACCGAATTCGAAATGGAGAGATGCACGACGTGCAtgaaaaattttagaaatatcgaCGAGTTGTGCATACACCAAAACGATACGGGTCATCTAGAACTGAAACAAACCCCTCAAGGCCCGGGTTATCTCTGTTGGAAGAAAGGCTGCAATCAATACTTCAACAACGCTCAGGCGCTGCAGATGCATTTCAAAGAGATCCACGCGAAAAACTCCATATCAAACATGTCAGTGTCGGAAAaacacgtatataaatatagatgtaaTCAATGCAGTTTAGCTTTTAAAACTATGGAAAAGTTGCAATTGCATTCGCAATATCATATGATCAGAGACGCGACGAAGTGCGTTTTATGCGGTCGCAGCTTCCGGTCTATTTTGGCGCTGCAAAAACACGTCGAAACTTCGCATTCGGAACTTACGGACGAAGAAGTCGCGGCTTTTAAACAGAGCCTGCTCAACAATCCTCTGTTGCTGGCTGGACTTCAAGGTCAAGTACTTGACAGTTCGACTACCGAATTACTGAAGAAAGAATCTCTCAAATTGACCGAAGAGGAAATGATGGAGCTGGAAGAGAGTAAAGATATGAACAATATGAGTAACGAAGACGGCAATCAAGTTGACGGCGAAGGCTCCGACGATTCTATCGTATATAAagatcaattatttttagaagattatttaaattcgCAAGCGATGGCCGAGGATTCGTACAATGATCCGAATAGAAAATACAAATGCCACCGCTGCAAAGTGGCCTTCACCAGACAATCTTATTTGACGTCACATAACAAGACGCTATTGCACAGAAAGGGCGAAAAGCTGACCTATCCCATGGAAAAGTATCTCGATCCGAACAGGCCGTTCAAATGCGACGTGTGCAAGGAGTCGTTCACGCAAAAGAACATACTCTTAGTGCATTATAATAGCGTGAGTCATCTGCATAAATTGAAGAGGGCCATGCAAGAGCAACAAAACAATAACAACGTGACGCCTAGTTCTCCGGGCGTCGGCGGTACTCTCAATTCGTCCAATTTGGCGCTGACGCCCAAGAGCACGTCCAGCGAGGAAGATGATAAAAAGCGGTACAAATGCAATATATGCAAAGTGGCGTATACACAAGGAAGCACGTTAGATATTCATATGCGATCTGTTTTGCATCAGACTAGAGCGAGTAAATTGCAAGATTTAGCCATATCGGGTCAGATCGATTTATCTAAACCGCTCATAGAACAGCCGGATAATAAACAGGATCCCGCGAAAATATTCCAAGACATGCTGTCGCCTAAAAACACATCCCCTTCGTCTTCTTCGAGCGGTGGGAATAGGGAGCAGCTCAGTGCGCATCGAGCGCTCTATTGTATCTTCGGCGCCGGGAGCGCCGCGCTAGCGGCCGCCGGTTTGGCCCACCTGGACCAGCATTCCGACGCAGACATGGTGGCCAAGACAAACCTCCCCAAGAGGAACAACTCTCAAATATACAAACACTTGCTCGAGTCGTTCGGCTTCGATTTAGTCATGCAATACAACGAGAACCACCAGCGACGACAGCTGAAAATTCAGCGCGAAAACGAAGAGAAAGAAAATCAGCGGATACCGACGCCTCCGGCGCCCCCCGTCGAGCCGGAACCGGAAGCGATCAAACTAGAAGAAGAACAGCCGGAAGTCGAACTACCAGAAGTCGCCAAATCCACGTGTCAACACTGCAATAAAGAATTTTCGAGTGTGTGGGTGCTGAAAACGCACTGCGAAGAAGTTCACAAGGATAAAGTGCCACTGGAGTTTTTAGAACAGTTCGCCGAACAATTCAAAAACGAATACGAAAAGAAGACTGTTGTCGTCACCGCGGCTACTTCGTCGACCGTTTCTTCGAGCCCGAGAGTGACGTCTCCGAATACCGATGCGCGACCGCCTTCAAATTCGGCGCCCCCAGCGTCGTCGGAAGCTGAAAACGCCGACGAGCGAGAGAACGGAAACGGAAATCACGACGAGAGGCCCTCGTCTCGCAACACGCCCGCCCTTCAGCTGGCTCAGCACATGAGCGAAGTTCAAGCCGCCCTCGGAGTTATGCAACTGCAGCAACAGTTGGGTCAATTGCATCCGGTCGTGGCGCAAATGTTATCAATGGGACTACCTCTCGGATTGAACGTCGGAGCTTTGGCGGCCATGAACCTGCAGCCGCCGTTAGTGCCAATGATGCTGCCGCCTCCGCCCTTCGACCAGCTTTCGATGGGGGGAAACTATTCACCCCAAGATGGACAAGCGGCCCTCCTGAAACAGCAGCACGCCATGATGCAACATCAACAAGTGgCAAATGCAGCGGCCGCCAACCAAAAGCGGGCTCGCACTCGAATCACCGACGAGCAGTTGAAGATTTTAAGAGCGCATTTCGATATCAACAATTCGCCGAGCGAAGATGCTATTCACGAGATGGCCAGCCAGTCTGGTCTCCCGCCCAAGGTCATCAAGCATTGGTTCAGAAACACGTTGTTCAAAGAAAGACAGAGAAACAAAGACTCGCCGTACAACTTCAACAACCCTCCGTCGACGACCCTCAATTTGGAAGAATACGAAAAGACCGGAGAGACCAAAGTGACCCCTTTGAATTCGTCGGCCAGTTCGGACGAGGGAAAACCGCCGCCTgaaaaaaaaggcaaaaaatcATCGCCGACTCCGACGCCGACGCCGACGCCCAACAACATGTTCAATCAACCGGAAAATTTAGTCAAAACCGAACCGAGCGACGAGCCGATCTCTGACGAACATACTAAATACAACTCGTACGATAATAAACATCAAGAAGATAAAATGTTCAACTTTCCGATCGGACTGCCGCCACAGAGCCCTGTGTCGAGTCAGGCCGGATCCGATCATCATGCGCAAAATATGTCATCGCGGCCGCAAACGCCTAATCATCTATCACTGAGCTCTATCATACAATCTCAAATAGAATCTATACCGGCGTCTGCAATTCCTCAAGTCCAACAAATGGCCGGTCAAAACCATCCGTCGATGTTGCCGCCGAAACTCACGCCGCAAAACTTCGCTTCCCCAAACAACTTGCCCCCGAATGTCTTACCTATGACCCCAAACAGAAGCTTAAGCCCTGGTCGAGGCTTAAATGAATTCGGACTTTCCGGGGGCAATTCAAATGGGTCTAACAGTTCCGGAGGATCGTCCGGAAAGCGCGCGAACCGCACCCGATTTACGGACTATCAAATTAAAGTACTGCAGGAGTTTTTCGAGAACAACGCGTATCCCAAAGACGACGACTTAGAATACCTGTCGAAATTGCTGGGATTGAGTCCACGCGTTATAGTAGTTTGGTTTCAAAATGCGAGGCAAAAAGCGAGGAAAGTATACGAGAATCAACCGGCTGTCGAACAGCCGCTTCCCGGTATTCCAGACGAGGCGGGAGCCAATCGCTTTCAGAGGACTCCCGGTCTGAATTATCAATGCAAGAAATGCCAATTAGTATTCCAGCGTTATTACGAATTGATTCGCCATCAAAAGACGCATTGCTTCAAGGAAGAAGACGCCAAGAGGTCCGCTCAGGCTCAAGCGGCGGCGGCTCAAGTGGCCGCGACCCTCAGCAGCGAAGATTCGAACTCGAGCACCACCACTCATCACAGCGTGCCAGCAAGCCCGGTAATGAATATTCCGCAACCGCCTATTACGCCAACGCCTTCAGCTTCCAATTATCAATTGTCGCCGGTAACGACGCCGACGCCCAACGAAAGAACGCCGAACGACAGAGAGCAGAAAGAAGGAACATTTCAATGTGATAAATGTAATCTAGTCTTTCCTCGTTTCGAGCTGTGGCGCGAGCATCAATTAGTCCATATAATGAATCCTAATTTGTTTCCAACTTATCCACCAGATTCACCTTTCGGCATTCTTCAACAACATGCTCAATTGCAACAGTTAAACGCGTCGCTGGGGAACAGCGACCAGATGGGAGTTCCTCACCCGTTGATGTCGATGTTGAACAATCAGGCGAACAAGAGGAAATTCGACGAGTTTGAAGTGGAAGTCGATTCGGGCGATCAACCCAAAGATAAAAGACTGCGCACCACCATATTGCCGGAGCAATTAGATTATTTGTACCAAAAGTACCAGGTCGAATCGAATCCATCCAGGAAGATGTTAGAAAACATCGCGAGAGAGGTCGGACTGAAGAAGAGAGTCGTTCAAGTCTGGTTCCAAAACACGAGAGCGAGAGAGAGAAAGGGCCAGTTCAGAGCGCACGCTCAGGTGATCAACAAGAGATGTCCCTTTTGCCCTGCGCTTTTCAAAGTGAAGAGCGCTTTAGAAAGCCATCTGACTACTAAGCACGCCGATCAATGTTCGCGGGGAGAAATAAACATCGACGCGCTGCCGGACGAAGAACTCAGCATGGAGTCGTCGCCCAGCTTCGGATCACAACAAGGAGATAAGCCAGGAAATTTTTCGCAAGGGGGGGCAAATATGATGCCCCCCTTATTTCCGCCCTTTCATCCAGATATGGAgaaatttattaagcaatataaCGAAGAATCGATGAAGAGATACATCACCGAGCTCCAGGCTCACGCCGCAGCCCAGCAGAACGGGGACGAACCTAAAGAGCAGTCGAGTCGACCGGAAGGGGAAATCCCTTTAGATCTCAGTAAACCGGTAGACTTGTCTAGGCCGATGAAGGTAAACATGGACCACGAGCGCAACGCGTGCGAGCCCGGACCGCCGACAGATCTGAGCGAAAGATCTCTGTGCGACGAAAGATCGGATAGCATGTCGGAGACGACGGAGTTTTACGACGACGAGAGCAATCCTACGTCGCCGAGTTCTACCCAAAGCAACCAGAGACAGAATTCATCAGGAGGCAACAGCAAGAGATTCAGAACTCAAATGTCATCACTGCAAGTAAAAATCATGAAGTCGCTGTTTGGAGATTACAAGACGCCGACGATGGCCGAATGCGAGATGCTGGGAAGGGAGATCGGCCTGCCGAAGCGCGTAGTGCAAGTGTGGTTTCAGAACGCTCGCGCCAAAGAGAAGAAGCACAAGCTGGCGATGCAGAAATCTGGAGGGTCCGAATCTGAACCCAGAGGTCCGGAAGACTGCAAGTACTGTCAGTTCAAATACAGTCACAAGTATTCGGTGCAAGACCACGTGTTCACCAAGGGTCACATTGCGGCAGTTCGCGCCGCTTTAGAGGGCAGTTCGGTTCCTAGAGAAGACAACGGCCCTCTGGCCCTCCTGATGGCCGCCAGACTGGAAGGTCGCGAAGACGAGCTCCTGAGGAGGCTGTGCGCCTCAGCTTCTCCCGCTGCTCCTTCAAGACCGCTGCTGCCATCCTACCCGCCCAACGGTGAGTGTCCGACTTAG
Protein Sequence: MLKFLEQQQHLHQQMQQQMQQQHQQQQQHLSQQQQQQQSQQQQQSQEENNTDQHSCPFCNFTCDSELRLQAHVVAQHGAPTPTPPAFLCPLCQDGFRDRPALERHVMQIHSVNSEGLQRLLMLVDQSHWLNSTRLVSPDSVASSKDSAQKNDSANLEEEREISSPHSEENTEFEMERCTTCMKNFRNIDELCIHQNDTGHLELKQTPQGPGYLCWKKGCNQYFNNAQALQMHFKEIHAKNSISNMSVSEKHVYKYRCNQCSLAFKTMEKLQLHSQYHMIRDATKCVLCGRSFRSILALQKHVETSHSELTDEEVAAFKQSLLNNPLLLAGLQGQVLDSSTTELLKKESLKLTEEEMMELEESKDMNNMSNEDGNQVDGEGSDDSIVYKDQLFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNVTPSSPGVGGTLNSSNLALTPKSTSSEEDDKKRYKCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAISGQIDLSKPLIEQPDNKQDPAKIFQDMLSPKNTSPSSSSSGGNREQLSAHRALYCIFGAGSAALAAAGLAHLDQHSDADMVAKTNLPKRNNSQIYKHLLESFGFDLVMQYNENHQRRQLKIQRENEEKENQRIPTPPAPPVEPEPEAIKLEEEQPEVELPEVAKSTCQHCNKEFSSVWVLKTHCEEVHKDKVPLEFLEQFAEQFKNEYEKKTVVVTAATSSTVSSSPRVTSPNTDARPPSNSAPPASSEAENADERENGNGNHDERPSSRNTPALQLAQHMSEVQAALGVMQLQQQLGQLHPVVAQMLSMGLPLGLNVGALAAMNLQPPLVPMMLPPPPFDQLSMGGNYSPQDGQAALLKQQHAMMQHQQVANAAAANQKRARTRITDEQLKILRAHFDINNSPSEDAIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGETKVTPLNSSASSDEGKPPPEKKGKKSSPTPTPTPTPNNMFNQPENLVKTEPSDEPISDEHTKYNSYDNKHQEDKMFNFPIGLPPQSPVSSQAGSDHHAQNMSSRPQTPNHLSLSSIIQSQIESIPASAIPQVQQMAGQNHPSMLPPKLTPQNFASPNNLPPNVLPMTPNRSLSPGRGLNEFGLSGGNSNGSNSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAVEQPLPGIPDEAGANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTTTHHSVPASPVMNIPQPPITPTPSASNYQLSPVTTPTPNERTPNDREQKEGTFQCDKCNLVFPRFELWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLGNSDQMGVPHPLMSMLNNQANKRKFDEFEVEVDSGDQPKDKRLRTTILPEQLDYLYQKYQVESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCSRGEINIDALPDEELSMESSPSFGSQQGDKPGNFSQGGANMMPPLFPPFHPDMEKFIKQYNEESMKRYITELQAHAAAQQNGDEPKEQSSRPEGEIPLDLSKPVDLSRPMKVNMDHERNACEPGPPTDLSERSLCDERSDSMSETTEFYDDESNPTSPSSTQSNQRQNSSGGNSKRFRTQMSSLQVKIMKSLFGDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKHKLAMQKSGGSESEPRGPEDCKYCQFKYSHKYSVQDHVFTKGHIAAVRAALEGSSVPREDNGPLALLMAARLEGREDELLRRLCASASPAAPSRPLLPSYPPNGECPT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00178985;
90% Identity: iTF_01218164;
80% Identity: iTF_01218164;