Pcon005212.1
Basic Information
- Insect
- Plectrocnemia conspersa
- Gene Symbol
- ZFX
- Assembly
- GCA_009617715.1
- Location
- VTFK01000059.1:882702-887905[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00033 0.029 15.2 0.9 1 23 343 365 343 365 0.98 2 11 0.13 11 7.1 2.4 1 23 372 394 372 394 0.98 3 11 0.11 9.6 7.3 0.9 1 23 398 421 398 421 0.93 4 11 3e-06 0.00026 21.7 1.5 1 23 428 450 428 450 0.98 5 11 2e-05 0.0017 19.1 0.3 3 23 458 478 456 478 0.97 6 11 3.9e-05 0.0034 18.2 0.7 1 23 484 506 484 506 0.97 7 11 7.5e-06 0.00066 20.4 1.7 1 22 512 533 512 537 0.94 8 11 0.0047 0.41 11.6 0.4 3 23 547 568 545 568 0.93 9 11 3.7e-05 0.0032 18.2 0.6 1 23 574 597 574 597 0.98 10 11 2.2e-05 0.0019 18.9 0.3 1 23 606 628 606 628 0.97 11 11 1.8e-06 0.00016 22.3 0.6 1 23 634 657 634 657 0.97
Sequence Information
- Coding Sequence
- atgtCGGAATCTTGGAGTCGCGTGTGCAGAGCTTGCCTCGAAAGTTCTAGACCATTAAGAGACCTCTTGCTCACCGCAAAATGCCAAGATTTTGCTATTCTGACTGGCATAGAGGTGTCAAAATTAGACGGTCTTCCGAGTTGGATATGCAACGAATGCTTCTACTATGTCTCAAAATTTCACAAATTCAGAGAGAAGACTAGGATGTCACAAAATATTCTTCTTAACTTCTTGAAGGAGTATCAATATGGAACTGaaaataaaGATCGCATGAGTCTTTTAAACGTACAGAGAGGGTCGATCAATAGCTTGTCCCTTTCAAAATCAAACACTTTAGTCCTAGACTTCATCAATCCAAAGCCAGATAAGAGCCACAAAAGTGTGTATTCGTTGCAGCGCAATAATGCGACGGAGAAGAATTACTGCCGCGATATGGTTCCGATCGCAAATCCTGAAAAACTGCTTACTttcgatcatatttttaataatgctccTCAAGAAGACGATGCGATTTCATTGTGCGAGGTTAAATTGGAAGATATGGATAATGATTTTAATCATTTCGCTTTCGATATGGGAAACGAGACGAGTAAAAATAGTGTTGATgttaaaaaagaaattaaaagttTGAAACGTCATGCGAAAGAAGTCGGAGAAAAAAAGAGAGCTTTGGACTCAAACGAACTGGATAGTAACGATGATCATTTTGACTTTGAAGACGACGGCGACTCCAGCGTCGAAATGCCCAAAGTGAAAAAGTCTCGAAAAAACAAAGAGTCTAAGCATAAAAAAGGAAAGGGGAAGAAAAGGTTCAGAGATGATAAAAAAGAAATCAATTCTgaaattgttatgaaaaaatctcaaaatgaaTTATTGATAAGTAATTCTAAATCTGAGACGACTCCGGAGTATAACAGTCGTATGGTGCTTGAAACGGAACAATATAAAGTAATCAAATTGACCAGAGAACAACTACTATTAGAAATGGTGGAAAATtctaaaagtgaaaaatatttgtattcccCATACAAATGTACTTTATGCGTTAAAGGTTTCAATTATGAAGACGTCTTACAAAATCATATGACTAAACACGAACCTaaaaatggACCATTCGAATGCGATCTCTGTCATCAGTGTTTGCCGTCCGCTGTGTCTATGCGAGGACATAAAAAATCTCACAGTACCAAATATCAGTGCAAGAAGTGTGGAGTGATCAAAGCTTCGCGTCAGCATTTGTTGGAACATTATATGTTGGTTCACGAAGGCTCGCCAAGAACTTATATTTGCAACGTCTGCGGAAAAACACTAACgaAAAGGACTATGTTTCAAAAGCACATGAGGATACATTACCCGTCTAATAAGATCGCCTGTGAAAAATGTGGGAAGCTCTTTAAAACCATCGAAACCCTCAGAGCTCATATGCTaAGACACGCGGATGTAAAACGCTACTCGTGCGATCAGTGTCCAAAAGCATTTCGCTACGCGTCTCTACTCTACACTCACAAAGTCACGCACATAACTACCAAAAACTTCTACTGTGTAGAGTGCGACATGAGATTCAAGACTCAGTCTAATCTGCGACTGCATTTGAGAAAGTCTTTGAAACACATCGATCCGGATAGCTTGAAATTCGGGTGTGATCAGTGCGATAAGAGATACGATGACGAGAAAGGTCTGCGTCATCACGTTGAATGGGTGCATCTCGGTCAGAAGAATTATAAATGCGGCAAATGTGAAATGCAGTTTGGTTCTCAAGATGGTTTGCGGAGTCATATGAAGAAGATTCACGACGGGATACGGCCGGCACGTACTCATATTTGTGAAATTTGCAATAAAGCATTTAGGgCTAAAGCTGTActcataaaacatattagagTACACACAGGAGAGCGACCCTACGAGTGCAAAGAATGCGGTAAGAAGTTCGCACAAAATTCCACCATGTCCACCCACATCAAGTTGGTTCATCTGAAAATGACGAGACACGTCAACAAGAAGAAGTGCAATGAAAACAACGTTCAAGAAGTCCATAACAAAATACCAGTGGTAGAAGACTTCGCCATACCTATGCAACAATGCATCGAGCCCCCGCCGACCGATCACACAGGTGTGCCTTATTACTTTCCACCGAGCTCGAGCAATCCGAACATCAGACACGTTCACATCCCCATAATGAAATTTGAAAGCGATTCGAGATAA
- Protein Sequence
- MSESWSRVCRACLESSRPLRDLLLTAKCQDFAILTGIEVSKLDGLPSWICNECFYYVSKFHKFREKTRMSQNILLNFLKEYQYGTENKDRMSLLNVQRGSINSLSLSKSNTLVLDFINPKPDKSHKSVYSLQRNNATEKNYCRDMVPIANPEKLLTFDHIFNNAPQEDDAISLCEVKLEDMDNDFNHFAFDMGNETSKNSVDVKKEIKSLKRHAKEVGEKKRALDSNELDSNDDHFDFEDDGDSSVEMPKVKKSRKNKESKHKKGKGKKRFRDDKKEINSEIVMKKSQNELLISNSKSETTPEYNSRMVLETEQYKVIKLTREQLLLEMVENSKSEKYLYSPYKCTLCVKGFNYEDVLQNHMTKHEPKNGPFECDLCHQCLPSAVSMRGHKKSHSTKYQCKKCGVIKASRQHLLEHYMLVHEGSPRTYICNVCGKTLTKRTMFQKHMRIHYPSNKIACEKCGKLFKTIETLRAHMLRHADVKRYSCDQCPKAFRYASLLYTHKVTHITTKNFYCVECDMRFKTQSNLRLHLRKSLKHIDPDSLKFGCDQCDKRYDDEKGLRHHVEWVHLGQKNYKCGKCEMQFGSQDGLRSHMKKIHDGIRPARTHICEICNKAFRAKAVLIKHIRVHTGERPYECKECGKKFAQNSTMSTHIKLVHLKMTRHVNKKKCNENNVQEVHNKIPVVEDFAIPMQQCIEPPPTDHTGVPYYFPPSSSNPNIRHVHIPIMKFESDSR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -