Basic Information

Insect: Plebejus argus
Gene Symbol: ZEB1
Assembly: GCA_905404155.1
Location: FR989926.1:12886449-12897737[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.022 1.7 9.7 0.6 1 23 361 383 361 383 0.95

2 10 0.27 20 6.3 4.3 1 23 390 412 390 413 0.94

3 10 0.0052 0.39 11.7 0.3 1 23 417 439 417 439 0.96

4 10 0.002 0.15 13.0 3.0 1 23 444 467 444 467 0.97

5 10 0.0016 0.12 13.3 0.7 1 23 471 494 471 494 0.96

6 10 0.058 4.4 8.4 0.1 2 20 506 524 506 526 0.93

7 10 0.033 2.5 9.1 3.8 2 23 599 620 598 620 0.95

8 10 1.4e-06 0.0001 22.9 2.8 1 23 626 648 626 648 0.99

9 10 0.091 6.9 7.8 4.7 1 23 655 678 655 678 0.97

10 10 0.00025 0.019 15.8 0.2 1 23 684 707 684 707 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.022	1.7	9.7	0.6	1	23	361	383	361	383	0.95
2	10	0.27	20	6.3	4.3	1	23	390	412	390	413	0.94
3	10	0.0052	0.39	11.7	0.3	1	23	417	439	417	439	0.96
4	10	0.002	0.15	13.0	3.0	1	23	444	467	444	467	0.97
5	10	0.0016	0.12	13.3	0.7	1	23	471	494	471	494	0.96
6	10	0.058	4.4	8.4	0.1	2	20	506	524	506	526	0.93
7	10	0.033	2.5	9.1	3.8	2	23	599	620	598	620	0.95
8	10	1.4e-06	0.0001	22.9	2.8	1	23	626	648	626	648	0.99
9	10	0.091	6.9	7.8	4.7	1	23	655	678	655	678	0.97
10	10	0.00025	0.019	15.8	0.2	1	23	684	707	684	707	0.91

Sequence Information

Coding Sequence: ATGCCGATGCGTACGCTCCGATCCAGTGGACGCGCAGCTTTAACCGTAAAACTTAAAAGAATACCAAAAGAGTACCATTTGAAACAGTTATGGTTAGAAGCTATTGGTACACCAGAGTGGGAGCTACGGTGCAATAGTGCAGTATGCTCTACACACTTTAGAGAATTTGATTTGACAATCTCAGAAACAGGAGAGAAGTTGCTTAAAGATGGTGCAGTACCTAGCCTATGTCTTAACACACTAGAAGATCTACAGGCACAAGCTGACTTCAAAACCTGCAGGGTGTGCCTAGCCATGGACAGGAAAATGTTCAACATCAAGGACCACAACCTTCATCACCTGTACAAGATGATTGTCGGAGTCACGGTGGAGGCTAGAGACGGCCTGCCCCAGATGATGTGTTGGGAGTGCACCAGTAAACTATTGTCGTTAAAGAAATTCAAAGAGCAGGCACAAACATCACAACTACTGTTGTCAAATAAGCTAGCTTTAAATAATATCCTCACTGTTGGTGATATAAAATCCATAGACCGTGTACATTATAATCTGAAATCTAGCCTCACAATGAAGCACTATGAACCAAACGAGTTTGACTTTTACATAGAAGTGTTCGAACTGAACATGAAACCCATGGAGATGCTACTGGATATTAAACCTGAACGTGACCAGGAACCCACTTTGGAGCTCAGTGGAATGTCCCCCAAACGTGAGATCCCTAAATGCAGCAAAGCTGAGCCGGAATCCACTATTTTGGTTGAAATGTTAGATTTGAAACAGAACATAGATGTGAAGGATATAACCGACCATATCAGTGATGAACACGATAGTAATATGTCGCTACATCCACAACATAGCGATAGCGAGATAGAAACTAAACCAGTTAGGAAACAAGTGAAAAGAAAAGCTACAGCAGCAAAGAGAAAGAGACCTATAACAGAAGTAAATGTGAAAAGAAAGAGGAAAAATGCGAGAGGTCCGAGGATCGAGCTGCCCGGGTTCGAAGTGCGTAAGCTGACGCTGGAGGAGCAGCAGGCGGCGGTGGCGGCGCGCGCGAACTCCTCCGCGTACCTCGACGCGCCCTACAAGTGCAACGTCTGCTTCAAGGGGTTCCTGTCTGAGAGAACCCTCGCCAGGCACGCCGTGCGGCACACCGAGAAGTGCGGCAAGTACAGGTGCGCGGTGTGCAAGTACCGGTACCGGCTGGAGAGGCACGTGCGCACACACGTCGTTACGCATCACACCAACCAGTACACCTGCAAAGTCTGCGGTCTGGTCACGCAGAGCAGCTCTACAGCTAAGAATCACCAGGATTGGCATGATGGCAGCACCTACCAGTGCCCGCACTGCCCCACCACACTCACCAAGTACACATCGTACATGTCGCACCTGCGGCTCAAGCACTCGTCGCGGTTCTCGTGCGAGCTGTGCGGCTACACCTTCATCAGCGAGCGCGGTGTGCAGACACACAAGAACAAGAGCCACGTCCTGGACGCTCAGGAGGTGCTGGCCGGTCCGTACTGCGAGGAGTGCAAGCTGCGGTTCGCCAGCGACGAGGCCTATCAGCGCCATCTCACGCAGTCCTCCGTACACAGCAGCGACGACGACCCGAATCGCGTCCGGAATGAAATATATACATATAAGCTGCACCCGCGGAAGGAAGTCAAGCGGCGTACGGCCGGCAAACCGATACCTTGCGAGGAGTGTGGTGAGCAGCAGGACAACTACAGAGCGTACGGGAAACACTTCCGCGCGGCGCACCCCGGCCTCAACCGCACCAAGTTCAGAGGAAACTGCATGTGCGAGCAGTGCGGCAAGAGGTTTCAGTGCAAGGCTCTCTTGCTGGATCATATGCTGTCACACTCCGGCGAGAAGCGGTTTAAATGCCAGACGTGTGACAAGGCATTCACACACAAGAACACTCTAGCTGTGCACCAACGCGTACACGGCGCGAAGGTTCCTATCTACCACTGTCCCTACTGTGACCGACAGTTCCACTTCTATCCGAACCGCGACCGCCACGTGAAGACCGTGCACAAGGGCATGAAGCAGTTCCAGTGCGAGATCTGCGGCAAGGAGTTCACGTCGGCGGCCGGCCAGCGCGCGCACGTCGACCACGTGCACCACAAGAAGCCCCGCCCCAAACGCGTGCGCGCACGTGCTCCGACCGCCCCGCCCACCGCTTACCGCGACTAA
Protein Sequence: MPMRTLRSSGRAALTVKLKRIPKEYHLKQLWLEAIGTPEWELRCNSAVCSTHFREFDLTISETGEKLLKDGAVPSLCLNTLEDLQAQADFKTCRVCLAMDRKMFNIKDHNLHHLYKMIVGVTVEARDGLPQMMCWECTSKLLSLKKFKEQAQTSQLLLSNKLALNNILTVGDIKSIDRVHYNLKSSLTMKHYEPNEFDFYIEVFELNMKPMEMLLDIKPERDQEPTLELSGMSPKREIPKCSKAEPESTILVEMLDLKQNIDVKDITDHISDEHDSNMSLHPQHSDSEIETKPVRKQVKRKATAAKRKRPITEVNVKRKRKNARGPRIELPGFEVRKLTLEEQQAAVAARANSSAYLDAPYKCNVCFKGFLSERTLARHAVRHTEKCGKYRCAVCKYRYRLERHVRTHVVTHHTNQYTCKVCGLVTQSSSTAKNHQDWHDGSTYQCPHCPTTLTKYTSYMSHLRLKHSSRFSCELCGYTFISERGVQTHKNKSHVLDAQEVLAGPYCEECKLRFASDEAYQRHLTQSSVHSSDDDPNRVRNEIYTYKLHPRKEVKRRTAGKPIPCEECGEQQDNYRAYGKHFRAAHPGLNRTKFRGNCMCEQCGKRFQCKALLLDHMLSHSGEKRFKCQTCDKAFTHKNTLAVHQRVHGAKVPIYHCPYCDRQFHFYPNRDRHVKTVHKGMKQFQCEICGKEFTSAAGQRAHVDHVHHKKPRPKRVRARAPTAPPTAYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00164712;
90% Identity: iTF_00164712;
80% Identity: iTF_01217578;