Basic Information

Insect: Platyscapa corneri
Gene Symbol: ZEB2_1
Assembly: GCA_018907185.1
Location: JACCHW010000021.1:1427543-1439922[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 29 0.036 12 8.3 0.1 1 23 83 106 83 106 0.93

2 29 6e-05 0.02 17.0 3.9 1 23 112 134 112 134 0.98

3 29 1.5e-05 0.005 18.9 6.0 1 23 155 177 155 177 0.97

4 29 0.00037 0.12 14.5 4.8 2 23 183 204 182 204 0.97

5 29 0.0024 0.8 12.0 0.1 1 23 209 231 209 231 0.98

6 29 5.7e-06 0.0019 20.2 1.4 1 23 239 261 239 261 0.98

7 29 0.00031 0.1 14.8 0.3 3 23 303 323 301 323 0.96

8 29 1.7e-06 0.00058 21.9 1.8 1 23 329 351 329 351 0.96

9 29 4.5e-08 1.5e-05 26.9 0.2 1 23 357 379 357 379 0.98

10 29 3.5e-07 0.00012 24.1 0.9 1 23 385 407 385 407 0.98

11 29 0.00086 0.29 13.4 0.8 1 21 413 433 413 434 0.96

12 29 0.042 14 8.1 0.4 3 23 481 502 480 502 0.92

13 29 0.0022 0.74 12.1 2.5 1 23 506 528 506 528 0.99

14 29 0.0048 1.6 11.0 2.4 1 23 534 557 534 557 0.94

15 29 0.00011 0.036 16.2 4.0 1 23 564 587 564 587 0.96

16 29 5 1.7e+03 1.6 0.8 2 15 593 606 592 613 0.76

17 29 0.00015 0.051 15.8 2.0 1 23 624 646 624 646 0.98

18 29 4.4e-05 0.015 17.4 0.2 1 23 650 672 650 672 0.98

19 29 0.0028 0.96 11.8 1.1 5 23 680 698 677 698 0.93

20 29 2.4e-06 0.00082 21.4 1.7 1 23 704 726 704 726 0.99

21 29 6.4 2.1e+03 1.2 0.1 1 7 993 999 993 1010 0.87

22 29 1.3e-06 0.00045 22.2 2.9 1 23 1022 1044 1022 1044 0.98

23 29 0.021 6.9 9.1 2.2 1 23 1053 1076 1053 1076 0.95

24 29 8.6e-06 0.0029 19.7 1.8 1 23 1082 1104 1082 1104 0.98

25 29 0.0008 0.27 13.5 2.0 1 23 1109 1131 1109 1131 0.97

26 29 0.00023 0.077 15.2 0.2 1 23 1137 1159 1137 1159 0.98

27 29 2.6e-07 8.9e-05 24.4 0.8 1 23 1163 1185 1163 1185 0.99

28 29 0.00015 0.049 15.8 0.0 1 23 1191 1213 1191 1213 0.95

29 29 0.0013 0.42 12.9 0.6 1 23 1219 1242 1219 1242 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	29	0.036	12	8.3	0.1	1	23	83	106	83	106	0.93
2	29	6e-05	0.02	17.0	3.9	1	23	112	134	112	134	0.98
3	29	1.5e-05	0.005	18.9	6.0	1	23	155	177	155	177	0.97
4	29	0.00037	0.12	14.5	4.8	2	23	183	204	182	204	0.97
5	29	0.0024	0.8	12.0	0.1	1	23	209	231	209	231	0.98
6	29	5.7e-06	0.0019	20.2	1.4	1	23	239	261	239	261	0.98
7	29	0.00031	0.1	14.8	0.3	3	23	303	323	301	323	0.96
8	29	1.7e-06	0.00058	21.9	1.8	1	23	329	351	329	351	0.96
9	29	4.5e-08	1.5e-05	26.9	0.2	1	23	357	379	357	379	0.98
10	29	3.5e-07	0.00012	24.1	0.9	1	23	385	407	385	407	0.98
11	29	0.00086	0.29	13.4	0.8	1	21	413	433	413	434	0.96
12	29	0.042	14	8.1	0.4	3	23	481	502	480	502	0.92
13	29	0.0022	0.74	12.1	2.5	1	23	506	528	506	528	0.99
14	29	0.0048	1.6	11.0	2.4	1	23	534	557	534	557	0.94
15	29	0.00011	0.036	16.2	4.0	1	23	564	587	564	587	0.96
16	29	5	1.7e+03	1.6	0.8	2	15	593	606	592	613	0.76
17	29	0.00015	0.051	15.8	2.0	1	23	624	646	624	646	0.98
18	29	4.4e-05	0.015	17.4	0.2	1	23	650	672	650	672	0.98
19	29	0.0028	0.96	11.8	1.1	5	23	680	698	677	698	0.93
20	29	2.4e-06	0.00082	21.4	1.7	1	23	704	726	704	726	0.99
21	29	6.4	2.1e+03	1.2	0.1	1	7	993	999	993	1010	0.87
22	29	1.3e-06	0.00045	22.2	2.9	1	23	1022	1044	1022	1044	0.98
23	29	0.021	6.9	9.1	2.2	1	23	1053	1076	1053	1076	0.95
24	29	8.6e-06	0.0029	19.7	1.8	1	23	1082	1104	1082	1104	0.98
25	29	0.0008	0.27	13.5	2.0	1	23	1109	1131	1109	1131	0.97
26	29	0.00023	0.077	15.2	0.2	1	23	1137	1159	1137	1159	0.98
27	29	2.6e-07	8.9e-05	24.4	0.8	1	23	1163	1185	1163	1185	0.99
28	29	0.00015	0.049	15.8	0.0	1	23	1191	1213	1191	1213	0.95
29	29	0.0013	0.42	12.9	0.6	1	23	1219	1242	1219	1242	0.97

Sequence Information

Coding Sequence: ATGATCATTCTAAATGAATCATCATTTGCCTATTCCGAGCGCTATTATCCACTGACGATATTGGGCCAAGAAATAGACGAGAAAACGACTGCCATATCAGAAGACAGGCTTGCCCTCTCGCCAACTCCTGCATCGATAATCACGAAGAAGAAGCAACAGATGAAGAAACTTGAAACCGAGCCGATTATCGTCAAGATTGAGGATAACCACGAACAAACGGTATTGGACGACGACCTCCCATTAGCTTATTATTGCAAACCCTGCGGAGTATTTTTTGCCTCCCAAGAGCTCCTGGACACGCACTTGTTAGCGATGCACAAAGTCAAAAAGAGATACGACTGTGCGCATTGCGGCAAAAGTTGTCGCACGGCGCTGAGTCTTCGTCAGCACATAAAGCGCCACAAGAACTTTACGAAAAAAGCCGATAAAGAAAGGCAGGAGCAACAAGACGAGGATGCGGAGTTTACGTGCAAAACCTGCAACAGGGTGTTCCGTCACAAGAGCAATTACCAGAAGCATCTGGTAAGGCACACCGTGGGCGACCTCACCTGCAAACATTGTCCGAAAAAATTCCGACTCTTCCGAGATCTCACGCGCCACGAGAAGACGCACTTTTTACCGAGTTACATGTGCAAGGAGTGTGACTACGAAACTACTGTGCTAGCGGCGCTGAGCATACACATGACGAGGCACACCGACAAGGCGGACTTGCCGTTCAAGTGTAACGAGTGCGAGAAGCGGTTCAGGAAGGCGACGGAACTTCAAGAGCATTACAACATACACTCGGGTGACAAGCCTTTCGTTTGTCAGGCGTGCACAAGCGCATTTTTCCTAAGAAGACAGCTCTCAGCGCATTGCAGACGCCTGCATCCCGAGCTGAAGGCGCAGAAGGTGACGAGTACCGCCTGTGACATATGCGGCAGGGTCTTGGCGACCAAGCGCTCGCTCTTCAGGCACAAGGAGAGTCATAACCCTATTAAGCTTTACCTGTGCGACTATTGCGGTAAAAGCTTGAGCAGTGCCGAGCATCTTAAAAAGCACCGGCGAATACATACCGGCGAAAAGCCTTACGTGTGCGACATATGTGGAAAAGGATTCACGGACTCTGAGAATCTTCGGATGCACAGGAGAGTCCACACCGGGGAGAAACCGTACAAGTGTGATCAGTGCCCGAAAGCCTTCAGTCAGAGGTCGACTCTAACCATTCACAGGAGAGGCCATACCGGAGAGAGACCTTACGTCTGTCAAATTTGCCAGAGAGGATTCTCGTGTCAAGGCAACTTGACAGCTCATCAGAAAAGCTCCAGCTGCCTTCAAAAAACGGCTACAGAAACCTGTGCCGAGGATCTCCCTAACCTTGGGAATAACTCTTACCGCGTGCGCCGCAAGCCAAGCTGGCTCAAAGATAGCGTGACCGACTTCGATAGCTTGCGGGATCTATGTCCGTTCTGCGACAAGCGCTTTAAAGATGATCGTCGGGTAGCTATGCACGTACGCAATGTTCACAAAAAGCCCTACAAGTGCGACTTGTGCCGACGCCAATACTTCAGCCAAGAGGTTCTCGAAAAGCACCGCAAAACCCACAATACCGATTCGCACTTCGAGTGCACGGTCTGCCACCTCAAGTACAAGCGGGAGGAGACGCTTCAGTATCATTACGTGCGAGTGCACAGCAATATCGAGCCCAATTTTCGCTGCGAACACTGCGGTAAGTGTTACAAGCTTAAGCAAGACCTAATGCTGCACATCAATCAGGTGCACATGTGCAGCTATCAGGTCTGTCGCTTTTGCGGCAAGACCGTGAAGAACGTCAAGGCGCACGAGTGGCACCACCAGAAGAAGCTTGATAAATCTAACAACGAGCAAGTCTTTCCGTGCAGCCTCTGCTTCAAAAAGTTCCGTAGTGAGACGAAACTCGAGAATCATCTTATGCGTCACGTGCAGAGATACAGGTGCCAGGAGTGCGACGAAACCTTCCCGGGCCCAGGGCAGCTCATGAATCACAAATCTAAGCATAGGCCTGGCATCAACTGCATCATCTGTCAGAAATTTTTTACCTCCAGAAGCAATTACTATCAGCACGTACTCATGCACGCCAAAGTCAGACCCTACAAGTGCGACGTCTGTCAGGAGGACTTTACCCAGCGATCAACGTTAGTCAGACATAGAAAGACGCATCCCGGTCCTATTACAAATCCATTAGCACAAGTGCCCATCGCTGATCTTGCCAGAAAGGTAAAAAATGAGTTTGAAACACAGCAACAATCACAGCCTCAACAACAGCCATTACTAATTTTGCCCCAATCTCAACAACAACATCAACAATCGTTTTTGTTGTTACAACAATCTCAACAACCATTGTTAATTTTGCAGCAACAGGTACAGAAACAAGAAAAACCACAACAGCCTCTTTTAATGTTGCAGCAACCACATGAACATAAAAAATTAATATTGCAATCACATCAGCAACAGAAATTAACATTGCAGTCGTCGGAACATCTCCAAGATCAACGACAGAATCATAATCAGCAACAAATTATTAATTTAGATACTCAAGACCCCCTCGGAATTTCTATGCCTATTTTGTCAGGAACAGAACCGCATAGAGAGCATTGCAACCTTAAACTGAGAGCTCTGAAATCACTACGGACACCTAAATCGATGAAAACACAAAAGTCTCAAAAAATATCGAAACTCAAATTTCCGATTGCTGAACAGGTTCAAATGAAGAAGAAAACATTAGAACTGGAAGATTCTTCATTACATCAACAGTACAACTCAACTCAGCTAAAATCTTTAGCAATTCAAAACTTTACTTTCATGCAAGAACTCCCTTCTACTTCGCAAGAAAGCATTGCAGGCCCGCATTCTTCTCTTAATTCTGATGATAACGACGAAGATCTTGAAAGCGATGATTTAAAGGAAGATGCGGATGAAGATATGAAAGAAATCTACACGCGAATAGATTGCGGTGGCTATAAGTGCAATATCTGCGAATTAACGAGGCTTGATCGACGAAGTATGCTTTTTCATATATCTGGTCAACACAGTCATTTGCGACCCTTCAAATGTGGTTCGTGCGATAAAACGTTCAAACGCAAATACTCCCTAAAAGTACACCAACTGTCACACAATCTGAAAAATGCTGTTGAGACTTATGCTTGCGAGAAGTGCAGCTACAGCACACCTAACAAAGTGTCCCTGCGATATCACCACTATCGGGTACACACGAACGAATATCGCTTTACGTGTGAACATTGTGGAAAGCGTTTCAAGGTTAAGCGGGAGTTGGTGGATCATCTCGTAACGCACAGTGGCATCCAGCACATGTGCGACATATGTGGAAAATTGTACAGAGGTGAGCATTTACTGAGAGCCCATCGCCGCCTACACTTAGATCTATACAAATTTCAATGTGTAATTTGTAAAAAAAAATTAGCTACGGAAGACGGTTTGGCTAATCACATGAAATTGCACAATAGAACGTATAAATGTGACGAGTGTGGCATGAAGTTTCCTAGCAAGTACAATCTTATTAAGCACAGAAATGTACATACGAGAGAGCAAGCTTTTCCTTGTCCAGAGTGTGGAAAAGTTTTTGCTGATCAACCGACCCAAAAGGTTCATTCGCTTATTCATGCTGGTTTAAAACCGTACAGATGTAACGTTTGCGGTCTAGGATTTACTCAAAGAACGCCAATGATGCTACATTGGAAGAAAAAACACCCCGGAGAAACCGATCCTCCTCCACCAGTAATTTTGAAGAACATATTAAAAAGTATTGAAGAGCAAAATGGAAAAAAGAGTCCAACGGAAAAATGA
Protein Sequence: MIILNESSFAYSERYYPLTILGQEIDEKTTAISEDRLALSPTPASIITKKKQQMKKLETEPIIVKIEDNHEQTVLDDDLPLAYYCKPCGVFFASQELLDTHLLAMHKVKKRYDCAHCGKSCRTALSLRQHIKRHKNFTKKADKERQEQQDEDAEFTCKTCNRVFRHKSNYQKHLVRHTVGDLTCKHCPKKFRLFRDLTRHEKTHFLPSYMCKECDYETTVLAALSIHMTRHTDKADLPFKCNECEKRFRKATELQEHYNIHSGDKPFVCQACTSAFFLRRQLSAHCRRLHPELKAQKVTSTACDICGRVLATKRSLFRHKESHNPIKLYLCDYCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICQRGFSCQGNLTAHQKSSSCLQKTATETCAEDLPNLGNNSYRVRRKPSWLKDSVTDFDSLRDLCPFCDKRFKDDRRVAMHVRNVHKKPYKCDLCRRQYFSQEVLEKHRKTHNTDSHFECTVCHLKYKREETLQYHYVRVHSNIEPNFRCEHCGKCYKLKQDLMLHINQVHMCSYQVCRFCGKTVKNVKAHEWHHQKKLDKSNNEQVFPCSLCFKKFRSETKLENHLMRHVQRYRCQECDETFPGPGQLMNHKSKHRPGINCIICQKFFTSRSNYYQHVLMHAKVRPYKCDVCQEDFTQRSTLVRHRKTHPGPITNPLAQVPIADLARKVKNEFETQQQSQPQQQPLLILPQSQQQHQQSFLLLQQSQQPLLILQQQVQKQEKPQQPLLMLQQPHEHKKLILQSHQQQKLTLQSSEHLQDQRQNHNQQQIINLDTQDPLGISMPILSGTEPHREHCNLKLRALKSLRTPKSMKTQKSQKISKLKFPIAEQVQMKKKTLELEDSSLHQQYNSTQLKSLAIQNFTFMQELPSTSQESIAGPHSSLNSDDNDEDLESDDLKEDADEDMKEIYTRIDCGGYKCNICELTRLDRRSMLFHISGQHSHLRPFKCGSCDKTFKRKYSLKVHQLSHNLKNAVETYACEKCSYSTPNKVSLRYHHYRVHTNEYRFTCEHCGKRFKVKRELVDHLVTHSGIQHMCDICGKLYRGEHLLRAHRRLHLDLYKFQCVICKKKLATEDGLANHMKLHNRTYKCDECGMKFPSKYNLIKHRNVHTREQAFPCPECGKVFADQPTQKVHSLIHAGLKPYRCNVCGLGFTQRTPMMLHWKKKHPGETDPPPPVILKNILKSIEEQNGKKSPTEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -