Pcyl008709.1
Basic Information
- Insect
- Platypus cylindrus
- Gene Symbol
- ZFX
- Assembly
- GCA_949748235.1
- Location
- OX456490.1:2936902-2944531[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 34 2.3 1.1e+02 3.5 8.2 1 23 142 164 142 165 0.90 2 34 0.11 5.4 7.6 0.1 3 23 175 194 174 194 0.95 3 34 0.0015 0.072 13.5 1.5 2 23 200 221 199 221 0.96 4 34 0.35 17 6.1 3.3 1 22 233 254 233 257 0.89 5 34 6.8e-05 0.0033 17.7 0.5 3 23 290 310 289 310 0.98 6 34 0.027 1.3 9.6 4.5 2 22 323 343 322 345 0.88 7 34 8.3e-06 0.0004 20.6 0.6 2 23 379 400 378 400 0.97 8 34 0.021 1 9.9 2.0 1 23 405 427 405 428 0.94 9 34 0.15 7.2 7.2 3.0 2 23 437 457 437 457 0.96 10 34 0.39 19 5.9 0.1 1 17 463 479 463 480 0.90 11 34 0.056 2.7 8.6 0.2 2 23 655 676 654 676 0.92 12 34 0.0013 0.063 13.7 2.5 2 23 682 703 681 704 0.95 13 34 0.00035 0.017 15.5 5.4 1 23 709 731 709 731 0.96 14 34 1.9 92 3.7 0.2 2 23 741 759 740 759 0.84 15 34 4.1e-05 0.002 18.4 0.5 1 23 765 787 765 787 0.98 16 34 0.00023 0.011 16.1 0.3 1 23 793 816 793 816 0.96 17 34 0.58 28 5.4 1.0 3 23 904 924 903 924 0.94 18 34 0.015 0.71 10.4 0.7 2 23 930 951 929 951 0.96 19 34 0.0088 0.43 11.1 2.4 1 23 956 978 956 978 0.98 20 34 0.23 11 6.6 1.5 3 23 1047 1067 1046 1067 0.95 21 34 0.18 8.7 7.0 3.3 3 23 1074 1094 1072 1094 0.95 22 34 0.089 4.3 7.9 4.1 1 23 1099 1121 1099 1121 0.97 23 34 0.24 11 6.6 1.9 2 23 1175 1196 1175 1196 0.94 24 34 0.0037 0.18 12.3 1.7 2 23 1203 1224 1202 1224 0.96 25 34 0.0051 0.25 11.8 4.1 1 23 1229 1251 1229 1251 0.98 26 34 6.2 3e+02 2.1 1.0 3 23 1262 1279 1261 1279 0.81 27 34 1.7e-05 0.00082 19.6 0.5 2 23 1286 1307 1285 1307 0.97 28 34 0.00075 0.036 14.5 1.7 1 21 1313 1333 1313 1334 0.95 29 34 0.01 0.49 10.9 0.5 1 23 1429 1452 1429 1452 0.95 30 34 0.26 13 6.4 3.5 3 23 1486 1507 1484 1507 0.94 31 34 0.04 1.9 9.0 6.6 1 23 1512 1534 1512 1534 0.95 32 34 0.21 10 6.8 1.5 3 23 1545 1562 1543 1562 0.92 33 34 0.12 5.8 7.5 0.9 2 23 1569 1590 1568 1590 0.92 34 34 9.7e-05 0.0047 17.3 1.0 1 23 1596 1619 1596 1619 0.98
Sequence Information
- Coding Sequence
- ATGGATTTGAAAAAGATTTGTAGAACTTGCCTACGTATTCCTATAAAATCTgttgatttatttaaagacAATGAACTTTTGCAAAAAATTAACGCTATTGCTTCCATCAAACTTGAAAGCAACGAAGAACTGTCCCAAACAATATGTGAGGAATgtgtaaaaaatataaatcattCATTCAAGTTTCGAAAGTTAATACGAAATACCAATAATGATTTACAGTCGCGACTTGAAACATTAAAAGAAACGAATTATACATGTAAAGCCAGAAGTGATACAGACAATAAATCTATTGGTTTCGTGAATGTCAATGATATATCAGAACccgaaaatgataaaaatgaacagaatGGTTCTATTTCTATTGAGAATAATATAAACGGAGACATGAATAATGAAGATCAAAGCGAAAAAGAATGTATGCACAAATGTGGCCAATGCGATAAAATGTTCGAtacgaaaaagaaattatattgtCATGTATCCTATCATCATAGCCTACTTGGTACATCTAAAAGTGCATGTAATATATGCGGAAAAGAAATGATTGCTTATAATTTAAAAGCGCATATGAAATTACATTCCCAAAACCCATGTCGTTGCAAAGAATGtggaaatatattaaaaaattcagTATCATTAGCATCCCACATGAGAAaccatagaaaaaataaactgcaaataaaaaaagcaaGCCATAAATGTGAAGAGTGTGgtaatattttcaattcaaatgtAAAATTACAATGCCATTATCGTCAAACTGGCCATGGTGAAACAAAGATCGAGTGCAATATCTGTGGAACTAAAATACGTCGTTGTCATTTACCAAATCATGTCAAACTCCATTCGGAGCCGCCACGTAACTGTAAAGTAtgtggaaaattattaaaaaattccgATACATTAGCGTGGCATATGCGAACACATCTTAATAAGAAACGTTTAATAACAAAATGTATTTGCAAATGTGATAAGTGTAATAGAATCTTtgatacaaaacaaaaattacaaaGTCACGTATATTTTAATCATGGAGGTGGCAATTCTACTGTTTTATGTAGTATATGTGGTAAACAAATGTCGATAAGGATTATAAAAGCACATATAAAAACCCATACAGAAGGAGCATGCCGTTGTCAAGAGTGTGgaaaagtattaaaaaattcTGGATCGCTAGCAATCCATATGAGAATACATTCGAATAAAGAGTTCAATTGTGAAGTGTGtggtaaaatatttaatgtaaaagcTTATCACACAGAACATGTGCGAGTCCATCATACAGATCAAGAGGATCGTAAAGCAACTTGTCACATTTGCGGACAGAAAATTGTTCGTAAAGCTATGAAAAGGCATATGAGAAAACATACTGGCGAAAGACGACATGTGTGTTCGTATTGTAACAAAGGCTTAACTAGCTCGAATGCACTAAAGGTTATACATCTATACCGACCGATACAAATCGGTATGGATTTACAAAAAGTTTGTAGACTTTGCCTTCGTATTCCAAAACAaccaattaatttatttgaaaatcaaCTTTTAGAGAAAATAGAAGCTATATCGTCAATACAGGTCAATATCGTAAATGAATTCTCTGATCAAATTTGTATTGAATGTTTAAGACtgataaatatttcatataaattcAGATTAGTGATAATAAATTCAGATAATGATTTAAATACTCGATTGAAAACATTGAAACAGACCAACTATTTAACCAAACGAAGAACAGATGTTAGAACAAATAATCCGATTAACTcgacaaaaacaaacaataccGAATTACATTTCGATAGAATTAAGGAATCAGATCCAGATATTAAacaagaaattgaaaaagtgACTGAAGATAAATCTGTGGAGAGAAACCATGAATGTCATACatctaaaaaaaattgctCTAAATCTAAAGCATTAAAAGCCGATAAAAGTATTTATCATGCTAGACGTATCGTATGCAATATTTGTGGACAAGAATTTTACTATTACAgtataaaaaaacatattcaAGCGAAACACACTAGACAACCATCACGTTGTAATGAATGTGGAAAAATATGCATACATCCCGGAGcattaattatacataaacGAGAACATCATGCACCCAAAGAATTTGCCTGTCATTTCTGTGGAAAAACATTTTCGCAAATGTCTCGCTTAACAagacattttaaatatcaCAATAAAGagaTTGTAAACCGTCGTAaaacatgttcaatttgtGGAAAAATAGTTGCATCAATAGAAAGACATATGCTGACTCACAGTGGTGGAAGGCCATATGTTTGTACGTATTGTAATAAAGGACTGACCAGCGCTTAtgcattaaaaatacataccCGATCACATACAAATGAACGACCTTACGCATGTACATATTGTGATGCATCTTATCCACAACCTGTATCGTTAAGAACACATTTAAAGAATAAACATGGTATTATTCGTATTGGAAATATGCACGTGTCGTACAGGTTTAGAGTATTAATTCGAAATTCGTATAAACATTTAAACAACAGATTAAAAGAGGCCGAAGTTTTAGCAAAACgaaaaacaatagaaattgAATCAGCTTCGGAAAAAAACGAGACATCAAATTCAGGCATAAATGAGGCACCAGATGATGATGAACTAATCCAAAATCAGCAAATGCATAAATATCATGAATGGTTTTATAAAAAcgttgaaaatattttatgccATATTTGCGGAATACAAATTCAAGCTCGTAATTTAAAGTCgcatataaattttcaacatgaAAACACCCCAATAGTTTGTGATGAATGTGGTAAATTGTGCATGCATGCTGGAGCATTAAGAATACATAAAGAAACGCATGCACCTAAAAAGTTTTCATGTCCATTTTGTGAGAAAAGTTTTCCTCTTATGTGTCGCCTGACTGTACATTTAAAAACTCACAATAAAAGTTCGAATGTAACGgaagtaattaaaattgtgCCAGTTTCAGAAAGCATCGAGACATCCGATATAAGTACTATCGATATAACGTTAGTTACAGAATCTGCTGCTGTTGATGAACCAAATTCAAAGCTAAACGAagtaatcaaaaaaaaacaaactaccAAGTACGATGGAAATTATAATACCGTTGAACGTGTTGCATGCAATATTTGCGGAGTAAAAATTCAATGTCGGAATTTAAAGAGGCATATAAATTTACAACACATAAGAACTCCAGTGCATTGTGATGAATGCGGTAAATTATGCAAACATGTTGGAGCATTACGAATACATAAAGAAAGTCATCAACCGAAAAAGTTTTCATGTCATCTTTGTGAGAAAACATTTCCTCTTATGTGTCGTCTGACTGCACATTTAAAACTTCACAATAAAAGTTCGTATGTGATGAGAAGGATTAAATTTACTGCACCTGAATTACCAAATATCAAGGCATCAAATACAAAAAGAACTGAGACATCAAATTCAAAGTCAGATCAATCAATCGACAAacgaaaaattcaaaagtgtccgaattttgaaaataatgtaTGCCATATTTGTGGAATACAAGTTCAAGCTTGTAATTTAAAAGCGCATATAAAGTTTCGACATGCAAAAAGTGCCCCAGTGCCTTGTGATGAATGTGGTAAATTATGCACACATGCTCGAGCATTAAGAGTACATAAACAAAGTCATCAACCGAAAAATTTTTCATGTCACGTTTGTGGTAAAACATTTCCTCTTATGTGTCGCCTGACTACACATTTAAAAGTTCACGATAAAGAATACCATAGGCCAAAAAGGGATTGTTTGATTTGTGGAAAATCGGTTATATCAATAACAAAACATATGCGTAGTCATACTGGAGAAAAACCTTGGGTTTGTACTTACTGCAAAAAGGGGCTTTCAGACAAAACAGCACTGCAAAGGCACATGCGTTTACATACAAACGAACGACCTCACGTGTGTACACATTGTGGAAGTTCTTATCGACAACGTGTATCATTAAGAACACATataaaaagTATAACTGAACTCCCTGATCAAATTTGTGAAGAATGTTCAAAACTCCTAGACATCTCCTATAAATTCAGACTAGTAATTATAAATTCAGATAATGATTTAAATAGTAGATTGGTAACGTTAAAAGAAACGAATTATTTAACCAAAAGAAGAACAACAGAATGCACCACCATTTCTCCTAGTTCGATAAAAACCGAATCAAATACACATTCTAGAGTTTCTATACGACctaaaaaaactattaaaagtAATCAAACAAATAGATCTCATACGAAATCACGAACATATCAGTGTGACCTATGCAAAAAAGTTTACAATACAGGTAACGCCTACTGGAAACATAAAGAGTCTGCTCATAATACTAGATATGTTCTCTGCAATTTTTGTGGACGAAAACTTCTATATCGGAATGTAAAAAAGCACATTATAGCAAAACATAAAGGTGAACCAGTTCATTGTGATATATGTGGCAAATTATGTATACATACTGAAGCATTAAAAGTGCATAAGAAGGAGAATCATGCACCTAAAGAGTTTTCATGTCAATTTTGTGGAAAAACATTTTGTCGAATGTGTCGTCTGAAAGCACATTTGGGATATCATACTAAAGAAAACAAACGTCCAAGAGTTTGTTGTTCGATTTGTGGGAAAGTCGTTACATCACTGAGGAGACATATGCTTAGTCACACTGGTGAACGACCACATATTTGCATCTATTGCAATAAAGGCATGTCCAGTGCGTATGCACTAAAAGTACATACGCGATCACATACAAATGAACGACCATATACATGTACATATTGTGATGCTGCTTATACCCAAACTGTTTCACTAAGGACACATTTGAGAAGTAAACATGGCATTACGTAA
- Protein Sequence
- MDLKKICRTCLRIPIKSVDLFKDNELLQKINAIASIKLESNEELSQTICEECVKNINHSFKFRKLIRNTNNDLQSRLETLKETNYTCKARSDTDNKSIGFVNVNDISEPENDKNEQNGSISIENNINGDMNNEDQSEKECMHKCGQCDKMFDTKKKLYCHVSYHHSLLGTSKSACNICGKEMIAYNLKAHMKLHSQNPCRCKECGNILKNSVSLASHMRNHRKNKLQIKKASHKCEECGNIFNSNVKLQCHYRQTGHGETKIECNICGTKIRRCHLPNHVKLHSEPPRNCKVCGKLLKNSDTLAWHMRTHLNKKRLITKCICKCDKCNRIFDTKQKLQSHVYFNHGGGNSTVLCSICGKQMSIRIIKAHIKTHTEGACRCQECGKVLKNSGSLAIHMRIHSNKEFNCEVCGKIFNVKAYHTEHVRVHHTDQEDRKATCHICGQKIVRKAMKRHMRKHTGERRHVCSYCNKGLTSSNALKVIHLYRPIQIGMDLQKVCRLCLRIPKQPINLFENQLLEKIEAISSIQVNIVNEFSDQICIECLRLINISYKFRLVIINSDNDLNTRLKTLKQTNYLTKRRTDVRTNNPINSTKTNNTELHFDRIKESDPDIKQEIEKVTEDKSVERNHECHTSKKNCSKSKALKADKSIYHARRIVCNICGQEFYYYSIKKHIQAKHTRQPSRCNECGKICIHPGALIIHKREHHAPKEFACHFCGKTFSQMSRLTRHFKYHNKEIVNRRKTCSICGKIVASIERHMLTHSGGRPYVCTYCNKGLTSAYALKIHTRSHTNERPYACTYCDASYPQPVSLRTHLKNKHGIIRIGNMHVSYRFRVLIRNSYKHLNNRLKEAEVLAKRKTIEIESASEKNETSNSGINEAPDDDELIQNQQMHKYHEWFYKNVENILCHICGIQIQARNLKSHINFQHENTPIVCDECGKLCMHAGALRIHKETHAPKKFSCPFCEKSFPLMCRLTVHLKTHNKSSNVTEVIKIVPVSESIETSDISTIDITLVTESAAVDEPNSKLNEVIKKKQTTKYDGNYNTVERVACNICGVKIQCRNLKRHINLQHIRTPVHCDECGKLCKHVGALRIHKESHQPKKFSCHLCEKTFPLMCRLTAHLKLHNKSSYVMRRIKFTAPELPNIKASNTKRTETSNSKSDQSIDKRKIQKCPNFENNVCHICGIQVQACNLKAHIKFRHAKSAPVPCDECGKLCTHARALRVHKQSHQPKNFSCHVCGKTFPLMCRLTTHLKVHDKEYHRPKRDCLICGKSVISITKHMRSHTGEKPWVCTYCKKGLSDKTALQRHMRLHTNERPHVCTHCGSSYRQRVSLRTHIKSITELPDQICEECSKLLDISYKFRLVIINSDNDLNSRLVTLKETNYLTKRRTTECTTISPSSIKTESNTHSRVSIRPKKTIKSNQTNRSHTKSRTYQCDLCKKVYNTGNAYWKHKESAHNTRYVLCNFCGRKLLYRNVKKHIIAKHKGEPVHCDICGKLCIHTEALKVHKKENHAPKEFSCQFCGKTFCRMCRLKAHLGYHTKENKRPRVCCSICGKVVTSLRRHMLSHTGERPHICIYCNKGMSSAYALKVHTRSHTNERPYTCTYCDAAYTQTVSLRTHLRSKHGIT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -