Pcyl014976.1
Basic Information
- Insect
- Platypus cylindrus
- Gene Symbol
- -
- Assembly
- GCA_949748235.1
- Location
- OX456494.1:9048559-9050638[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00015 0.0071 16.7 3.4 1 23 32 54 32 54 0.95 2 19 0.02 0.97 10.0 5.2 1 23 59 82 59 82 0.94 3 19 0.042 2 9.0 0.3 2 23 89 111 88 111 0.93 4 19 8.9e-05 0.0043 17.4 0.2 1 23 117 139 117 139 0.96 5 19 9.7e-05 0.0047 17.3 0.2 1 23 144 166 144 166 0.95 6 19 0.0027 0.13 12.7 1.1 1 23 175 198 175 198 0.95 7 19 6.5e-07 3.1e-05 24.1 0.1 2 23 205 226 204 226 0.97 8 19 4.1e-05 0.002 18.4 3.0 1 23 232 254 232 254 0.98 9 19 0.073 3.5 8.2 0.6 1 14 260 273 260 274 0.91 10 19 0.00028 0.013 15.8 3.5 1 23 278 300 278 300 0.98 11 19 0.16 7.6 7.2 3.5 2 21 306 325 305 328 0.93 12 19 0.0019 0.093 13.2 3.2 1 23 334 357 334 357 0.95 13 19 6.3e-05 0.0031 17.8 2.6 1 23 363 386 363 386 0.95 14 19 8.4e-06 0.00041 20.6 2.6 2 23 392 413 391 413 0.97 15 19 0.00078 0.038 14.4 3.4 1 23 422 444 422 444 0.99 16 19 8.9e-07 4.3e-05 23.7 1.4 2 23 452 473 452 473 0.97 17 19 8.2e-06 0.0004 20.6 1.0 1 23 479 501 479 501 0.96 18 19 3.7e-06 0.00018 21.7 1.6 1 23 507 529 507 529 0.98 19 19 0.0094 0.45 11.0 2.0 1 20 535 554 535 556 0.94
Sequence Information
- Coding Sequence
- ATGAGAGCCAATGATTTATTAAAAGTTGAAGAATTAATAGTGAAGTGCGAACCGTATTGTGGCGAATATAATTCCGATCAAAAACCTGTCGCGTACAAATGTGAAATTTGTCAGAAATCATATCGGACAAAGCAAAAACTGTGGCAGCATAAAACTTTCCATAAGGAGAAAACTCATTCCTGTAATCAGTGTCCGAAAAAGTATCATTTCGCTTATATGCTTCGCAGACATGAAAAGCTATCGCATCAGGGCAAAGAACGGGTCGAATGTGAATTTTGTGGTCTGGCCTACTGGACGAAGCACGGATTGAAAAGTCACATTCAATTCGTCCATGAGAAAGTGTATAAATACATTTGCAACGAATGCGGCAAGGGATACGTTTCGAAGAAATTATTAATGGAACACGAGGATAAGCATAAAggaattaaatttgaatgtaAAATATGTGGAAAACCGTTTACAACACAAAAAGCTGCTGATGACCATGCAAACAAGCACAACCCCGAATATAAACCGCCCGAGTTTCAATGCGATTTATGCGGTAAAGTCTTTTCGGCAATACAATCGTATAAATTCCATTTGAGAACGTATCATACGACCAATTCGAAGTTAGTATGCGAACAGTGTGGAAAGGCAGTAACGTCAGCGTCATCATTACGGAATCATATACGCACTCATAATGGCGAGCGGCCGTTCGAATGTAAAACATGTCATAAAACGTTTAATAAAACTGGCAGTTTGGCTATACATGAGCGGACACATACAAAGGTAAAGCCACATGTATGTAAAGTATGTTTGAAGACGTTCACGCAACGTAGCACGCCATCTGATTTTACATGCACAAGCTGCTCAAAGAAATTCCAATCGAATCAAAAGTTGAAAAGGCACGCACGAATCCATCGAGCAAAAACTATACCGTGTCAATACTGCAGTAAATTCTTCCAGGAAAAACATATGTTGGACAAACATTTGAATTGTGTACATTTTAAGGAATTGAAATACAAGTGTACGGCGTGCGATAGGAAATTTCATCACTACGATGCATTGAGCCGACATATTGACAATGTGCATTACAATCAGTTTAAGTTCTCGTGTTCGTATTGTAAGAAGGGGTTTAATTTCCGTTACGAATTGATTAAACATCAGAATTTCATCCATAATGGATTACGGCTGACATGTGACAAATGCAATAAATCATTCAAAAACGAACAGTATTTTAGAGAACACATTAAAACGCACGACCCCGACTATATCAAAGCGCAGTATCGATGCGAGTACTGTTTGAAAATCTTCAATCATATCAAATCATTCAAAGTTCATTTGAAAATCCATACGGGCGAAATTGTGTTGAATGTGTGCGATATTTGCGGTAAGAATGTGACATCGAAAGCCAGTTTAAGACATCATATGCGCACGCATACCGGCGAAAAACCGTTTCAATGTGATGTTTGCGGCAAGAGTTTCACAACGCGAAATTTGATGCGAACTCATAAAGTCGTCCATTCAAAAGAGAAACCGTTCACGTGTGATGTTTGCTTGAAGAGTTTCACGCAAAAAGGAAGTCTGACAATTCATAGGCGTTACCATACGGGGGAGAAGCCATATGAATGCTCGTTATGTTTAAAAACTTATGTATCGCGTACGTTATTGAAGAATCATAAATGTTTAGGACCAAATTTGACATAG
- Protein Sequence
- MRANDLLKVEELIVKCEPYCGEYNSDQKPVAYKCEICQKSYRTKQKLWQHKTFHKEKTHSCNQCPKKYHFAYMLRRHEKLSHQGKERVECEFCGLAYWTKHGLKSHIQFVHEKVYKYICNECGKGYVSKKLLMEHEDKHKGIKFECKICGKPFTTQKAADDHANKHNPEYKPPEFQCDLCGKVFSAIQSYKFHLRTYHTTNSKLVCEQCGKAVTSASSLRNHIRTHNGERPFECKTCHKTFNKTGSLAIHERTHTKVKPHVCKVCLKTFTQRSTPSDFTCTSCSKKFQSNQKLKRHARIHRAKTIPCQYCSKFFQEKHMLDKHLNCVHFKELKYKCTACDRKFHHYDALSRHIDNVHYNQFKFSCSYCKKGFNFRYELIKHQNFIHNGLRLTCDKCNKSFKNEQYFREHIKTHDPDYIKAQYRCEYCLKIFNHIKSFKVHLKIHTGEIVLNVCDICGKNVTSKASLRHHMRTHTGEKPFQCDVCGKSFTTRNLMRTHKVVHSKEKPFTCDVCLKSFTQKGSLTIHRRYHTGEKPYECSLCLKTYVSRTLLKNHKCLGPNLT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -