Pcyl014978.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Platypus cylindrus
Gene Symbol
-
Assembly
GCA_949748235.1
Location
OX456494.1:9055199-9066198[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 60 0.68 33 5.2 0.8 1 23 20 44 20 44 0.67
2 60 0.00032 0.016 15.6 0.9 1 23 49 72 49 72 0.98
3 60 0.0019 0.091 13.2 0.1 1 23 79 102 79 102 0.98
4 60 0.00088 0.043 14.2 0.2 3 23 110 131 108 131 0.93
5 60 0.055 2.7 8.6 0.0 3 23 138 160 136 160 0.90
6 60 0.017 0.84 10.2 0.4 2 23 167 188 166 188 0.92
7 60 0.013 0.61 10.6 0.6 1 23 198 220 198 220 0.98
8 60 2.1 1e+02 3.6 0.3 1 11 226 236 226 239 0.87
9 60 0.56 27 5.4 1.8 3 23 266 287 264 287 0.88
10 60 4e-06 0.0002 21.6 1.1 1 23 292 315 292 315 0.98
11 60 0.00019 0.0093 16.3 3.4 1 23 322 345 322 345 0.97
12 60 0.1 4.9 7.8 1.5 3 23 353 374 351 374 0.93
13 60 0.04 1.9 9.0 0.6 1 23 381 405 381 405 0.90
14 60 0.00015 0.0071 16.7 1.7 2 23 412 433 411 433 0.95
15 60 6.4e-05 0.0031 17.8 1.0 1 23 440 462 440 462 0.98
16 60 0.84 41 4.9 0.6 1 14 468 481 468 481 0.85
17 60 0.084 4.1 8.0 1.3 1 23 516 539 516 539 0.95
18 60 8.3e-05 0.004 17.5 2.1 1 23 544 567 544 567 0.97
19 60 0.63 31 5.3 1.9 1 11 574 584 574 606 0.50
20 60 0.0012 0.058 13.8 0.6 2 20 612 632 611 634 0.91
21 60 2.1e-05 0.001 19.3 2.3 1 23 668 691 668 691 0.97
22 60 0.0048 0.23 11.9 1.4 2 23 697 719 696 719 0.94
23 60 0.018 0.87 10.1 0.6 1 23 726 749 726 749 0.95
24 60 0.0016 0.079 13.4 0.6 3 23 757 778 755 778 0.95
25 60 0.76 37 5.0 0.3 2 23 785 808 784 808 0.73
26 60 0.00012 0.006 16.9 1.8 2 23 815 836 815 836 0.95
27 60 1.4 66 4.2 5.5 1 23 843 865 843 865 0.96
28 60 3.8e-05 0.0019 18.5 0.4 1 23 871 893 871 893 0.96
29 60 0.00047 0.023 15.1 0.9 3 22 901 920 899 920 0.95
30 60 0.0095 0.46 11.0 1.1 1 23 951 974 951 974 0.93
31 60 0.011 0.55 10.8 0.1 3 23 981 1002 979 1002 0.97
32 60 0.00029 0.014 15.8 0.9 1 23 1009 1032 1009 1032 0.97
33 60 0.00012 0.0059 16.9 0.9 3 23 1040 1061 1038 1061 0.96
34 60 0.077 3.7 8.1 0.4 2 23 1067 1091 1066 1091 0.89
35 60 0.00044 0.021 15.2 2.3 2 23 1098 1119 1097 1119 0.93
36 60 0.0068 0.33 11.4 0.2 1 23 1126 1148 1126 1148 0.98
37 60 0.00093 0.045 14.2 0.3 1 23 1154 1176 1154 1176 0.95
38 60 5e-06 0.00024 21.3 0.3 2 23 1233 1255 1232 1255 0.96
39 60 1.1e-05 0.00053 20.2 1.0 1 23 1262 1285 1262 1285 0.97
40 60 0.00013 0.0064 16.8 1.3 3 23 1293 1313 1291 1313 0.96
41 60 0.0085 0.41 11.1 0.1 2 23 1320 1344 1319 1344 0.90
42 60 0.0035 0.17 12.4 0.7 2 23 1352 1373 1351 1373 0.95
43 60 0.0006 0.029 14.8 0.3 1 23 1380 1402 1380 1402 0.99
44 60 0.00014 0.0069 16.7 1.8 1 23 1408 1430 1408 1430 0.96
45 60 5.2 2.5e+02 2.4 1.4 1 13 1436 1448 1436 1449 0.90
46 60 5.8e-06 0.00028 21.1 1.9 1 23 1450 1473 1450 1473 0.96
47 60 0.00044 0.021 15.2 0.3 2 23 1479 1501 1478 1501 0.96
48 60 0.0016 0.076 13.5 0.6 1 23 1508 1531 1508 1531 0.97
49 60 0.005 0.24 11.9 1.7 2 23 1538 1560 1537 1560 0.94
50 60 8.1 3.9e+02 1.8 0.7 2 21 1567 1588 1566 1591 0.82
51 60 0.67 32 5.2 3.6 2 20 1614 1632 1613 1634 0.92
52 60 0.011 0.53 10.8 0.3 2 23 1664 1686 1663 1686 0.95
53 60 1.6e-05 0.0008 19.7 1.2 1 23 1691 1714 1691 1714 0.96
54 60 0.00053 0.026 14.9 0.2 1 23 1721 1744 1721 1744 0.97
55 60 0.025 1.2 9.7 0.3 1 23 1750 1773 1750 1773 0.96
56 60 1.8 88 3.8 0.1 2 23 1781 1805 1780 1805 0.86
57 60 0.0021 0.1 13.0 4.2 2 23 1813 1834 1812 1834 0.94
58 60 0.002 0.097 13.1 3.2 1 23 1841 1863 1841 1863 0.98
59 60 0.0021 0.1 13.1 1.7 1 23 1869 1891 1869 1891 0.96
60 60 0.00035 0.017 15.5 2.7 3 23 1899 1920 1897 1920 0.97

Sequence Information

Coding Sequence
ATGTCAACTAAACAATTCCAGTCATGGCAACAATATTATAATGAAATAACAAAGAGATTTCATTGTCCCGAATGCCCAAAAACATATGCGGCGAATGGTAGCGGTTTCAGTCGTCATTACCAGACAGTTCATAAGCATTGGAGATATTCTTGTCCTGTatgtttgaaaatatttagaaCAAAACCAGCAGTGAAGCATCACATTAAAAAAATCCATGAAAAAACTATTCCCGATTTTCAGTGCGATTTGTGTGGGAAAACTTATGCTGAAGTCGGAGGTTTAACGTATCATAAAAATACAGCTCACTTCAATATTTCTAAAATATTTTGCGAAATATGTGGCAAAGGATTTCAATATCAGAGTGGTTTGATCCAGCATAAAAAGGACGTGCATATCAAAGACCCGATAATTTGTAAAGAAGGCTGTGGAAAAATTTTACGTAGCATATCAGCATTACGCTACCATATGGTAGCAGTTCATAAAGCAAAAAGGCAGTTGATTTGTGATTAttgcaataaaatatttacaaatccAACTATATATCGACAGCATTTGCTTTTTCATAAAAATGGTAAACCGAACCGCAAGCAATTCGTTTGCGTAATTTGTAAGAAAAGTTTGAGTTCTGATAGTATTTTTAAGGACCATATGCGAATGCATACCGGAGAGAAACCGTTTTTATGCGAATTTTGTGGGAAAGCCTTTTCAGCCGAAAAcTCAAATGTCTCCGTTAAACACGAAAGCTTAACGAGTGAGCCAGAAAAACAAGGAAAAATAATTAACGAACCAGTTAATTGTTCGGAATGTTCAAAAACATATTTATCGAGGGACAGCCTCATCAGACATTGTAATTCAGTTCATAGAAGTTTGCGATTTTCATGTTCAGAATGTTCGAAGACGTTCAGCTACAAAGCGGGATTATTTCGACACATTCAAACGATCCATAGAAATACACGATCCGTTCATCAGTGCGACTATTGCGAGAAAAATTACAGCACGAAAAGCGCTTTAACGTATCATACAAACAGTAatcatttgaatatttttaaaatgttttgtgAATTGTGTGGTAAGGGATTCCAGGCTGAAAGTTGTTTGGCACGACATAAgaaagattttcatataaaaGATACGTTAAAATTCCGTTGTACAGAAGATGGTTGTGGGAAAAGGTTTAGTAAAGCAGGATTACATTATCACTTGTTAGCAGTTCATAGAGAGAAAAAGGAATTGATCTGTAACCAATGCAGTAAAGTGTTCACGCATCCAACATCATATCAGAGACATTTGttattacataaaaaaggTCCAAAACTGTTTATTTGCAATATTTGTAATAAACTGTTGAGCACATTAAGCAGTTTTCAAGATCATATGCGCACGCATACTGGCGAAACTCCATTTCTATGCGAAGTTTGCGGCAAAGGATTCTCtttttcttctatcaatataaaattaatcgGTACGAAAAAACAACAAGCAATCTGCAGAAAGTTGCAACTGAAAGAAGAAAATCGAAATGAAGAAATTGAAGCCTACGAACCGTTCAGTTGTCCAAAATGTTTCAAGACCTATTCTTCGATATTAGCTCGAAATCAACATCTAAATCGTATGCATAAAGGTTTGAGATTTCCTTGTTCAGAATGTTCTAAAGCATTCACTTTGAAATGTACCCTGAAGAGACATATTAAAGTGATCCATGATAATGAGCGTTCCGTTTATCAGTGTGATTTGTGTGGAAAAACTTATGCTGCAAAAGTGTGTGGCAAGGGATGTCAAAATGAAAGTGAATTAAATGTCCATAAAGAAGAGGTTCATGTTAAAGGCACGATAACTTGTAAGCAAGAGGGCTGTGGCAAAACTTTCACGAGTAAATCGGGATTACATTACCATACCCTCAATTTAGCTACTGAAGACGTGAAATTGATGTACCAAAGACAACATGAAACAGATAGTACACGGTTGCCGTTTGAACAATGCTTTAATGTAAATACGGGTCTGTTTTATTGCCCAGAATGCCCAAAAACATATTCATACAGACATAGTCTAATTAAACATTATAATTCGATTCATAAACATTTGCGACTCTCTTGTCCCGAATGCCCAAAAACGTTTTCGTCAAAATTTGGCATGAACTGCCATATTCAAAGGATCCATCGAAACAAGATTCAAGTCTATCAATGTGACCTTTGCGGAAATACTTATAATCAAGTAACTGCTCTAACATATCATAAGAATCAAgatcattttaaaatttttaaagtttGTTGTGAAATATGTGGCAAAGGATTCCAAACTGAAGGTTTTTTGAATGCCCATAAGAAAAGTGCTCATACCAAAGGCGCGCATCTAATGTGTAAAGTGGAGGGTTGTGGAAGAAAATTCAGTAAATCAggattatattttcatttattaacaGCTCATAGAGAAAGGAAAGAAAACACTTGTAATGAATGTGGCAAAGTGTTTACGCATCTGGTGGCATATAAGCGCCATTTGTCGTTTCATAGAAGAGGTCGTAAGCAATTTGTTTGtattatttgcaaaaaaaagtTATGCTCATCTCAGTCGTATCACAATCATGTTAGAACGCATAGTGGTGAGAAGCCGTTTATATGTGAATTGTGTGGAAAAGGATTTTCTACGAAAAACTATCTTCGAGAACATCGAGTTGTCCATACAAAAGAGAGACCTTTCGGTTGTAAACTGTGCGAAAAAAGATTTACTCAGCGAGGTACTTTGACTCTTCATATGAAAAGAATTGATTTTTCTACTGCCTATCTGAAAGAAACTGGACCAAATCCTAATCGTTTGTCGTTCAAAAAAtgctttaatttaaaaacgaAAAGATTTCATTGTCCACAGTGCCCAGTAACATATGCATCGAGAAGTAGTTTTAATGATCATTTTAAAGGAATTCACAAGAATTTGATTTATGGCTGTCCAGAATGTTCTAAGATACTTAAATCTAAAGCCGCTTTAGACTATCATATACAAACGATCCATAAGAATGAACGTTCCGGTCATCAATGTGACATTTGTGGGAAAACATATGCTGGAAAAGGTGGTCTGAAGTATCATAAAAATCGAGATcacttcaatatttttaaattgttttgcGAATTGTGTGGTAAAGGATTTCAAACTGAAAGTTTTTTAAATAGACATAAAAGAACAGTTCATATAAAAGACACGTTAACATGTCAAGCAGAAGATTGTGGTAAAACATTCAAATGTGAATCAGGATTGCAGTATCATGTGCTGGCAGTTCATAAAGAGAGAAAGGAATTGATTTGTAATTTATGCGATAAAGTATTCACGCATCCAACAACATATCGAAAGCATTTGTATTTCCATAAAAACGGTCGCAAGAAATTCGTTTGTGTAATTTGTACGAAGAGTTTGAGCTCTGCTCAGGTTTTTAAGGAACATCTACGAATCCATAGTGGAGAGAAACCGTTCATATGTGAATTCTGTGGAAAAGGATTTTCGGCCCAAAAATATTTGCGAGTCCATAAGGTCGTTCACACAAAGGAGCGACCGTTCGGTTGCAAATTTTGTGAAAAGACATTTTCTCAATGTGGGTCTTCTCATATTGATTTTGTGAATGTAAAGTTAATGGACAAGAAGGGATCACAAAAAAATCGCAATATCTCGACCTTAAAAGGAAATGCCCGAAAACGAAAAACCCCGATAAGCTGTCCAGAATGTTCCAAAACATTTACAGTAAAGTCTAGTATGGAACGACACATTCAAACGATACATAGAAATGAACGTCCAATTTATCCATGCGACCTTTGCGGCAAAACTTATGCTACGAAAAGTAGTTTGAAATATCATAAGAATCGAGAGCATTGGAATGTTTTCAAAGTGTGTTGCGAAATATGTGGCAAAGGATTTCAAACTGAAAGTTTTCTGATTCGTCACAGATTAACGCACAGCACAGAACTGTTAGTAAAATGTGAAGTAAAGGGTTGTGACAGAATATTCAAAGATCGATCAGGATTATCGTATCACATAGATGCAGTTCATGTTAAAGAGAAACCGAATTTAGTTTGTGATCAGTGCGGACGAATGTATACGCATCCGAAAGTATATAGACGGCATGTATTGTTACATAAAACTGGGCCTAAATCGTTCAAATGCAATGCTTGTAATAAAGTACTCATAAGTTTGGAAGGTTTCCAAGAGCATATGCGCACGCATACTAATGAAAGACCGTTTATATGTCAATTGTGTGGTAAAGCGTTTAAAGCgaaaaaacatcttcgaaacCATCGTGTTGTACACACAAAGGAAAAACCTTATGCTTGTAGATTTTGTGATAAAAAATATAGTCAAAATAGATTCGATTGCCCGGAATGTTCAAAAACATATACATCAAAGTATAATCTAATTAAACATTACAATTCAAAACATAAATGTTGGACAGTCTCCTGCCCTGAATGCCCAAAAAAATTCACAACAAAATTTGGTATGGATAGTCATATTCAGAAGATCCATCGAAATAAGATTCGGGTATATCAATGTGATCTTTGTGGAAATACGTATAATCAGGCAACTGCTCTAACCTATCATAAGAATCGAGATCATTTCAAGATATTTAAATGGTGTTGTGAAATTTGCGGTAAAGGATTCCAGGCTGAAAGCCACTTGAATATCCACAAGAAAAATGTTCACATCAAAGATACGATTCTGATGTGTAATAACGAGGGTTGTAAAAGAACATTTAGATGCTTGTCCGGATTGgcgtatcacaaagctgcagcTCATGTTAAGAACAAACCAAATTTAATTTGTGACCAATGTGGCAAAGTaaTTCGAATTGGACTAATTCTGCGATGCACTCAATGCAATTGTTACTTTAAAACCTATGAAAAACTGAGAGAGCACAGTAAGAATTGTGAAGGAGCTACCACCACTGATGAAAGTCACACTCAGACATCTAAAGAGGACACAGAATCAAAGATAAAAGTTGAGAGGCGTGTTCAATGTCCGCAATGCCCGAAAACGTATCTGTCAAAGCGCAGCCTTGGCAAACATATAAACTACGTTCATAAACGTGTGACATTTTCTTGCACTGAATGCACCAAAACGTTTGGTAGAAAAGAATCATTAAAATCTCACATTGAAAAAATCCATCAGAACATCTTCCGTTTTTATCAATGCGACATTTGCGGCGAGGAACTGAAAGGCAAAGTGAATCTTCGAAATCATAAACAAATCAAACATTTCAAAATGTATAAATTCTATTGCGAAGTATGTGGAAAGGGATTCCTTTTTCAAGGTGCAATGAATGCGCATAAGAAACGTGTACACGAAGGTCAAGTCTCGCTTGTTACATGCAAGGAGCCGGGTTGTAATAAGACATTCCTAAGTGGTGCCGGATTAAAATATCACATGTTCGCTGTTCATGTGCAAGAAAAACCGAAGTTGATTTGTGAACATTGCAGCAAGATATTTACTCATCCGAAATTGTTTAAGAAACACTTAACATTGCATCAGCATGATCGTAAAAGATTTACTTGTAATATTTGCAAAAAGGTTTTGAGCACATTGAGTAGTTGCCAGGATCATATGCGTAGCCACACTGATGAGAGACCGTTCATATGTGAAGTTTGCGGTAAAGGATTCCACGCCAAAAAACATCTGCAGGAACATCGTGTAGTGCACACAAAAGAGCGTCCTTACGGTTGTAAAATGTGCGATAAAACATTTACCCAACGTGGAACTTTGGGTCTTCATATGCAGAAATGTCATTCACATTAA
Protein Sequence
MSTKQFQSWQQYYNEITKRFHCPECPKTYAANGSGFSRHYQTVHKHWRYSCPVCLKIFRTKPAVKHHIKKIHEKTIPDFQCDLCGKTYAEVGGLTYHKNTAHFNISKIFCEICGKGFQYQSGLIQHKKDVHIKDPIICKEGCGKILRSISALRYHMVAVHKAKRQLICDYCNKIFTNPTIYRQHLLFHKNGKPNRKQFVCVICKKSLSSDSIFKDHMRMHTGEKPFLCEFCGKAFSAENSNVSVKHESLTSEPEKQGKIINEPVNCSECSKTYLSRDSLIRHCNSVHRSLRFSCSECSKTFSYKAGLFRHIQTIHRNTRSVHQCDYCEKNYSTKSALTYHTNSNHLNIFKMFCELCGKGFQAESCLARHKKDFHIKDTLKFRCTEDGCGKRFSKAGLHYHLLAVHREKKELICNQCSKVFTHPTSYQRHLLLHKKGPKLFICNICNKLLSTLSSFQDHMRTHTGETPFLCEVCGKGFSFSSINIKLIGTKKQQAICRKLQLKEENRNEEIEAYEPFSCPKCFKTYSSILARNQHLNRMHKGLRFPCSECSKAFTLKCTLKRHIKVIHDNERSVYQCDLCGKTYAAKVCGKGCQNESELNVHKEEVHVKGTITCKQEGCGKTFTSKSGLHYHTLNLATEDVKLMYQRQHETDSTRLPFEQCFNVNTGLFYCPECPKTYSYRHSLIKHYNSIHKHLRLSCPECPKTFSSKFGMNCHIQRIHRNKIQVYQCDLCGNTYNQVTALTYHKNQDHFKIFKVCCEICGKGFQTEGFLNAHKKSAHTKGAHLMCKVEGCGRKFSKSGLYFHLLTAHRERKENTCNECGKVFTHLVAYKRHLSFHRRGRKQFVCIICKKKLCSSQSYHNHVRTHSGEKPFICELCGKGFSTKNYLREHRVVHTKERPFGCKLCEKRFTQRGTLTLHMKRIDFSTAYLKETGPNPNRLSFKKCFNLKTKRFHCPQCPVTYASRSSFNDHFKGIHKNLIYGCPECSKILKSKAALDYHIQTIHKNERSGHQCDICGKTYAGKGGLKYHKNRDHFNIFKLFCELCGKGFQTESFLNRHKRTVHIKDTLTCQAEDCGKTFKCESGLQYHVLAVHKERKELICNLCDKVFTHPTTYRKHLYFHKNGRKKFVCVICTKSLSSAQVFKEHLRIHSGEKPFICEFCGKGFSAQKYLRVHKVVHTKERPFGCKFCEKTFSQCGSSHIDFVNVKLMDKKGSQKNRNISTLKGNARKRKTPISCPECSKTFTVKSSMERHIQTIHRNERPIYPCDLCGKTYATKSSLKYHKNREHWNVFKVCCEICGKGFQTESFLIRHRLTHSTELLVKCEVKGCDRIFKDRSGLSYHIDAVHVKEKPNLVCDQCGRMYTHPKVYRRHVLLHKTGPKSFKCNACNKVLISLEGFQEHMRTHTNERPFICQLCGKAFKAKKHLRNHRVVHTKEKPYACRFCDKKYSQNRFDCPECSKTYTSKYNLIKHYNSKHKCWTVSCPECPKKFTTKFGMDSHIQKIHRNKIRVYQCDLCGNTYNQATALTYHKNRDHFKIFKWCCEICGKGFQAESHLNIHKKNVHIKDTILMCNNEGCKRTFRCLSGLAYHKAAAHVKNKPNLICDQCGKVIRIGLILRCTQCNCYFKTYEKLREHSKNCEGATTTDESHTQTSKEDTESKIKVERRVQCPQCPKTYLSKRSLGKHINYVHKRVTFSCTECTKTFGRKESLKSHIEKIHQNIFRFYQCDICGEELKGKVNLRNHKQIKHFKMYKFYCEVCGKGFLFQGAMNAHKKRVHEGQVSLVTCKEPGCNKTFLSGAGLKYHMFAVHVQEKPKLICEHCSKIFTHPKLFKKHLTLHQHDRKRFTCNICKKVLSTLSSCQDHMRSHTDERPFICEVCGKGFHAKKHLQEHRVVHTKERPYGCKMCDKTFTQRGTLGLHMQKCHSH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-