Ppen131435.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Platycnemis pennipes
Gene Symbol
zfh2
Assembly
GCA_933228905.1
Location
CAKOGJ010005760.1:26055-39388[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.42 3e+02 5.1 0.5 2 21 214 233 213 237 0.90
2 11 0.015 10 9.7 0.2 3 23 253 276 251 276 0.86
3 11 0.012 8.8 9.9 1.7 1 23 315 337 315 337 0.97
4 11 0.0067 4.7 10.8 0.5 2 23 344 366 343 366 0.94
5 11 0.024 17 9.0 3.2 1 23 490 514 490 514 0.91
6 11 0.008 5.7 10.5 0.7 1 22 534 555 534 558 0.89
7 11 0.0018 1.3 12.6 0.2 1 23 617 641 617 641 0.93
8 11 0.095 68 7.1 0.2 1 21 864 884 864 885 0.92
9 11 0.00012 0.088 16.2 2.5 1 23 1718 1740 1718 1740 0.99
10 11 0.00085 0.61 13.6 0.3 1 23 1855 1877 1855 1877 0.98
11 11 0.013 9.5 9.8 0.2 2 23 2061 2083 2060 2083 0.95

Sequence Information

Coding Sequence
ATGCACACTGTCAGCCAGCAGCAGAAAGAAAGAATTGATTCAGCAAAGGAGGTCGCCAGCCAACAACAGCAGCAGGACAAACAGAGCATGCTTAAATATGCTCTTGAACAACAAGGAATGACTGCTGCAGATGAATGCTCTACGACTACTCCTCAGCCCAGTGAACTTCCTCAGACGCCAACGCATCAGCAGCAACATCAGAAGAGTGCCGGAAACGTGACTCCAGTGAACACCTCTTCCACATCTCCAGCATCTTCAACCTCTGCTACGTCTGTGGCGGCCATTTCTCCAGTTCACGATGGCTTTAAGGAGAAGGCCCTGCTGGAGAAACACGTCATGAGAATACACAGCGTCAATGCTGAAGGCCTGCAGCGGCTATTGCTCCTCGTGGACCAATCCCATTGGCTGAACACTGTCTCTCGTCCTCAAGGCCAGCAGAGTGGTGGAAGCCAAACTCAGGTAAACACAAGTCCACAATCTAGTAACGAACAGGACAATGCCAATAGAAGTCTTTCTTCTTCCGAGGGCACTAAAGAACCCAGCAGCGAAGGAGATGTCTCCTCTAGGGAAGATACGGTGGTAGCTCTGTCTCCATCAGAAAGTCAGCAGCAATCAGTTGAGGAAAATGAGGAAACACTTCGATGCCAAAGCTGCAGTAGATTTTTCCGGGGAGTGGATGATTTTATGAATCACCAGCTAGAAACTGGTCACATGGACACAGCAAAAGCCATTGGATGTGCTGGTGGTGGATATCTCTGCTGGAAGAAAGGCTGCGGTCAGTATTTTCCATCTGCCTCTAGCCTTCAGGCCCATTTCAAAGACATTCATGGCCGCGGGTTGACAAACACCCTCCAGCCAACTCCTTCGCCCACGCAGCATACGATTGGGACAAGCACCTCGAATACCCCTCCTGCTGCAGTTTCAGAAAAGCATGTTTACAAATATAGGTGCAGTCAGTGTTCACTTGCTTTCAAGACTATGGAGAAGCTTCAACTCCACTCCCAGTATCATATTATTAGGGACGCTACCAAATGCGCATTATGCGGACGAAGCTTTAGATCCATATTGGCGTTGCACAAACACGTAGAGAGTGCACACACGGACCTTCCTGAAGAAGAGCTTGCACAATATAAACAAAGTCTTTTGACCAATCCATTATTACTGGCAGGTCTGGGTGGTGGGCCAGTACCTGGGCTTGGAATGTTTCTTAGTGGTATGAAAAATGAAGCTGCAGCTACTCCTATCCCTATGGAGGTAGATGAAGAGACTAGtgctgctaccgcagctgctgatgaggaaatgatgatgatgatgGAGGCTGAGAGAGGAAGAGAAGACGGGGGAGGTGGACCTGGCGGTGGAGAAGAAAATAGCGATGACTCTGGTGGTAGAGAGCAACAGCTTTTGGAAGACTACTTGAATTCTCAAGCTGTAGCAGAGGATGGCTATAATGACCCTAATCGTAAATATAAGTGCCACAGATGTAAGGTAGCGTATACTAAGCAGTCGTATCTTACGGGGCATAATAAGACATTGTTGCACCGAAAGGGAGAAAAGTTATCGTATCCCATGGAAAAATATTTGGATCCTAACAGACCTTTCAAATGTGATGTATGCAAGGAGTCTTTCACTCAGAAGAATATTCTTCTTGTGCATTATAACTCCGTTAGTCACCTTCATAAGCTGAAAAGGGCAATGCAAGAACAGCAGCAGCCCACCAGTAATAATGGAGTGATGAATGTATCCTCTCCAACGACGCCAACGAATCAAAAAATGGTCAACGCTGTTTCATCTTCGAACGCCATGACACCAGTGTCAACTCCCAGTGACGAAGATGATAAGAAACCTTACAAATGTAATATATGCCGAGTGGCTTACAGCCAAGGTTCTACTTTGGATATACATATGCGATCGGTCCTTCATCAAACTAGAGCGTCAAAATTACAAGATCTGGCTCTTACTGGTCAAATCGATCTCAGTAGACCACTCATTGAACAACCAATGCAGACAGCCGCTCAAGCAGCTGCTGTTGCAGAAAAGACTTCTAACTTGTTGCACGACATACTAGGAACAGCTCAATCGCAAGCAGTCGCTGCAGCTACCTCGAGTGGAATGGTGACTCCTAAAAGCAGTCATGGCCATCACATCCATGGGCAGCAACAGACATCATTCCACTCGGGTCATCACGCTGCCACACACTTTGGTCAGCATTCCATCCACCATGGGTCAGCTGTGCAGACGCAACAATCACCGACATCGTTGTCATCAGCGTCTTCCACCGCTTCCTCCTCATCAACGGTTCCTTCACCCACCCAAGTGCCCAGTGGCGGTCCTAGCACGGCAGTCCAGTCAACAGTTCCTCCCACATCATCTCAGTCTACAACAGCCACTCAAGCATCATCCCCTGCCATATCTCCTACAGTTCCTAATTCCGCAACCAGTGTTACCGCTAATGTGACAAGCGGAGCTGGTGGCGAAGTAAATAGTCAGTCGGTCGGGGTAGGGAATACGACAAATGCTCAAACACCTGTGATAATGAATTCGTCTACGTCCTTGCAAGGACAACAACAGACACAGACCGGAGGAATGCATGCTTGTCCACGATGCAACGCGTTGTTTTCTAGCCAGGAACAGATGATGCAGCATACACAAATGTATTGCATGTATACTCAGCAGGCTACATTGCACCAGCAAGGAAGTACCACCAATACGGCCGCAACGGTGCCATCACCATCGCCGTCGCCGTCATCCGTTGCTGGACAGAGCACTGCAGGAGTGTCTACAACGACACCTACAGGAGCTACTCCGACCACTGCTGGAGGCACTGGCCTTCATCATCATCACCATCACCACCAGATtacTGGTAATAACACCCAATCTGCTAAAATTGAGCAACCAATGAACTCTCCGGATAAGGACGTTCAACCAGTAACCACCACCACACAAACTACAATGACTGGTGCTGATGAAGACCAGGAAGAAAAGATTGCCATGATGATGATGATGATGAAAGGTGAAAAGCCTTCATCCACATCTGTGAGTACGTCAACATCGACAATTCCGTTAAACCTCGGCCCGAGGATGTCTTCTACCCCGAACCCACATAGAAGGGCGGACAGCACCTCCCCGGAAGTTGTGCCAATACCATCCACTACTCCTACAACACCTACTGCCTCATCCACACCTGCTCCAATAGGAGATAACATCTCTTCAACCACTCCTTCGCAGGGAGCTGGGACCTCTTCTCCTGCCACTCCTAACCCTACCTCGACTACACCGAGACCGGTGTCGACGCCCAGAGATGACCATCAGCCTCATCATCATCAACAGCAAGGGCACGGAGGAGCGGCCTCTCAGGAGGGATCTGGTCAAGGATCGACACCTGGTACCCCGTCAAATGCGGCATCTGCGGCTGCTGCTGCATCAGCCATGCAGTTATCTTTGGCGGCTCAAATGAATGAGATGCAAGCCGCGATTAATTTAATGGCCATGCAGCAATTTCACAACCCAGCTACTGCTATGTCCATGATGCAAATGGCTGCTATGGGCTTGTCTCCTTTAGGCTTAATGAACCTCCAGCCTCCATTAGTTCCCATGATGATGGCACCACCACCACCTCCTCCTCCCGCCCAATCCCAACCCCCTGCCACCCATTCACCATCGCCATCTGACCAGTTGGCAGCCgccgcagctgcagctaattctttattctctcctgctggtctcctggtggctaagcagcaggctctactccagcagcagcaacacctaccgcacgtccctcagcatcaccatatggcgtcgcagttgcagcagcaacagcaacaacaacagcaacagcagaagaGAGCCCGGACCCGTATAACGGACGATCAGTTGAAAATTCTTCGTGCCCATTTTGATATTAATAATTCTCCATCCGAGGAGCAGATAGCGGAAATGGCTTCTCGTTCTGGCCTTCCGCCAAAGGTTATTAAGCACTGGTTCAGAAACACGCTTTTTAAAGAGAGGCAGAGGAATAAGGATTCACCCTACAATTTCAACAACCCACCATCTACTACTCTGAATTTAGAAGAGTATGAGAAAACAGGCGAAGCTAAAGTATCACCTTTGAATCCGGAAGAGCAGAAGGAATTGTTTAGTCAAGTCGTTCAGGCACAACAGTCTTCCTCCAACAAGAGGAAGCAGTCTCAACCAATACAAGCTCCTCAGCCTCCTCCGGTTTCTCCACCCCCTCAGCAACAAATGGAAAGAATTTCGGCTGAGTCTTCACTCATGGGTTATAAACCATCCGAGGATCAATATGGAGGAGACGACTTGTCTCGTTCTGTGAAAATGGAGCTAGACGAGGATGTGAAGCCAATTATCAATCTTACCGAGGAAAACACAAGGGATGAACCTGATTCGCCCGCATCAATGAACGTTCCCACATCTATCGGGACTCAAATTGGCAATTCCTTGGGAGTGCCGTTAAACATTCCTACTACTTCATCAAGGAATATCTCACCTGGTAATTTAACATTGACGTCAATAATAGCGTCACAGCTAGGATCTCAAGCTGAGGGAATTCCTGTAGCGCCCGTAACCTCCTCCTCGACCTCTCCGCATGCTGTCTCAGGAGGTGGTGCTGCATCTGCCAACATCCTCGCGCCTCCCAAGGCAGCGCCGTGCGCCACTATTTATTCTTCGCCGGTCCAGAGCCAAGTTCCTCCTAGTCCAACATCAATAATGGGTGTAACGCTGAGCAACACGCCCACATCCGTCGTATCTGGCGGTGGGATGATGGGAATGTCGACTCCTGTGTCCACCCTAAGCCCTGGCAGGTCTCCATCCTCCTCCATGGACTGCATGACCTCTGTCGGAGGAGGCAGTGGTGGAAGTGGCAGTTCCTCTGGGAAGAGAGCAAACAGGACAAGATTTACGGATTATCAAATCAAAGTCCTTCAGGAATTCTTTGAGAACAACGCATATCCCAAAGATGACGATTTGGAGTACTTATCAAAACTCCTGAGTTTAAGTCCTAGAGTCATCGTGGTTTGGTTTCAAAACGCCCGACAGAAGGCTAGGAAAGTGTACGAGAATCAACCACCGGTCGAGGCCACCGCGGGGGTGGAGGGCGCCGGGAGATTTCAGCGGACCCCCGGTCTCAACTACCAGTGCAAGAAATGCCTCCTGGTTTTCCAGAGGTATTACGAACTGATTCGGCACCAAAAGACCCACTGCTTCAAGGAGGAGGACGCCAAGAGGTCGGCGCAGGCACAGGCAGCCGCGGCCCAGATAGCCGCTGTTCTCAGCTCAGAAGACTCTAACTCGAGCTCCGTGGCGGAGTCTCGAGGCGTCGCCGACCTGTCATCCGTGTCGACGCCTTCGGTACCGCCGCCACCTCCTCCTCCTCCCCCGCCACCGCCTCCCCCGCCCCCGCCGCCCCCGTCCTTCGTCTCGGCGATGGCCCCCTCGCCCCCCACTCCCGACGGTCGCAAGAGCGCCCAGCCCGCAGAGGCCTCCCCACCGCCCACGCCCTCCCAGTCACACGGAGGTCACCAGGAGGCCTCCGAGGACAGTTTCCAGTGCGACAAGTGTAACCTAGTCTTCCCGCGATTCGAACTGTGGCGAGAGCACCAGCTGGTGCACATAATGAACCCTAACCTGTTCccgtcgtacccgcccgattcgccattcggcatcttgcagcagcacgcgcagatgcagcaacagcagcagcaacaacaacagcagcagcagcagacgcagcagaatccgcagctgcaccctgcctcgggccaccagcacttgggtggcatctcgggcgcggccgtggcggctgcggcggcggctgcagcgGCCGCCGCCGGGCTCTCTTACGAAGCGGGCATGGGCACGCTGTCTCCGCCCATCGGCCAGGGCAAGCGGAAGTTCGACGAAGTGGAGGAGGAGTTGAGAAGCGGCGGTGAGGAGAACGCCGCGCCCAAGGACAAGAGGCTGAGGACCACCATCTTACCGGAACAGCTCGACTACCTATACCAGAAATATCAGGTGGAGAGCAACCCGAGCCGTAAGATGCTGGAGTCGATCGCGCGGGAGGTTGGTCTGAAGAAGCGCGTCGTGCAGGTGTGGTTCCAAAACACGCGCGCGCGGGAGCGTAAGGGGCAGTTCAGAGCACACGCACAGGTCATCAACAAGCGCTGCCCGTTCTGCCCCGCCCTCTTCAAGGTGAAGTCAGCTCTCGAATCTCACTTGGCGTCGAAGCACGCTGACCAAGTCGCCGCCCGGGGCGGAGACGTCAACATCGACGCCCTGCCCGACGAAGAGCTGAGCGTCGACTCGTCCGCCTCCTTCTCGACCACCGGAGACGCGCAAGGGGGCGCCGCCCCGGGCAACACGACCCCCGGGGGCGGCAAGGCCGGCACCGGCGGCATGCTCTCCAGCGCCTTCCCGGGTGCCGCGTCCATGATGCAGCACAACATGATCTCCCCCCTCTTCTCGCCGTTCGCGGCCGCTGCAGCCGCGGCTGCCGCGTCTCAGGACGCCGAGAACTCCCTCAAGAAGTTCTACGAGGAGTCCATGAAGAGGTACATCAGCGAGATGCAGTCGCAGGCCGCGCAGAACGGGATCCCGGCGGTGTCGGGCTCGGCGGCCGCAGGAGGGGCCGTTCCCGCCACCGGCAGCGGCGGAACGGCCGGCGGGGCCACCGGTGGGGGTTCGGGAGGAACTAGCGGCGCGGCCCCAGCGACTCCTGCCAAGGAATCCCACGGAGCCACCGATCTGAGCATGAAGATCAAGCAGGAGATGGGGCAGTCTCCGGCCGAAGCAACCAGTGACGCCCCTCTGGACCTGAGCAAACCCGTCGACCTGAGCCGCCCTGTGAGGATCAGCACTGAGGCTGGCGGTGCGGACCAAGGTCCACTGACGGACATTAGTGAGCGAAGCGGAAGTGACGCCAGGTCGGACAGCTTGTCCGAAACGTGTACGGACAATATGGACGGCGACGAGAGCAACCCTACGAGTCCCGCTTCGAGCACCCAGTCGCAAAGGCACCAGACGACAGCAGCGGGGACGCCGGGCGCCGGGACGCCGTTGAGCGGCGGAAGCGGGGCCGGCTCGGGCAAGAGGTTCCGCACCCAAATGTCTAGTTTACAG
Protein Sequence
MHTVSQQQKERIDSAKEVASQQQQQDKQSMLKYALEQQGMTAADECSTTTPQPSELPQTPTHQQQHQKSAGNVTPVNTSSTSPASSTSATSVAAISPVHDGFKEKALLEKHVMRIHSVNAEGLQRLLLLVDQSHWLNTVSRPQGQQSGGSQTQVNTSPQSSNEQDNANRSLSSSEGTKEPSSEGDVSSREDTVVALSPSESQQQSVEENEETLRCQSCSRFFRGVDDFMNHQLETGHMDTAKAIGCAGGGYLCWKKGCGQYFPSASSLQAHFKDIHGRGLTNTLQPTPSPTQHTIGTSTSNTPPAAVSEKHVYKYRCSQCSLAFKTMEKLQLHSQYHIIRDATKCALCGRSFRSILALHKHVESAHTDLPEEELAQYKQSLLTNPLLLAGLGGGPVPGLGMFLSGMKNEAAATPIPMEVDEETSAATAAADEEMMMMMEAERGREDGGGGPGGGEENSDDSGGREQQLLEDYLNSQAVAEDGYNDPNRKYKCHRCKVAYTKQSYLTGHNKTLLHRKGEKLSYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQPTSNNGVMNVSSPTTPTNQKMVNAVSSSNAMTPVSTPSDEDDKKPYKCNICRVAYSQGSTLDIHMRSVLHQTRASKLQDLALTGQIDLSRPLIEQPMQTAAQAAAVAEKTSNLLHDILGTAQSQAVAAATSSGMVTPKSSHGHHIHGQQQTSFHSGHHAATHFGQHSIHHGSAVQTQQSPTSLSSASSTASSSSTVPSPTQVPSGGPSTAVQSTVPPTSSQSTTATQASSPAISPTVPNSATSVTANVTSGAGGEVNSQSVGVGNTTNAQTPVIMNSSTSLQGQQQTQTGGMHACPRCNALFSSQEQMMQHTQMYCMYTQQATLHQQGSTTNTAATVPSPSPSPSSVAGQSTAGVSTTTPTGATPTTAGGTGLHHHHHHHQITGNNTQSAKIEQPMNSPDKDVQPVTTTTQTTMTGADEDQEEKIAMMMMMMKGEKPSSTSVSTSTSTIPLNLGPRMSSTPNPHRRADSTSPEVVPIPSTTPTTPTASSTPAPIGDNISSTTPSQGAGTSSPATPNPTSTTPRPVSTPRDDHQPHHHQQQGHGGAASQEGSGQGSTPGTPSNAASAAAAASAMQLSLAAQMNEMQAAINLMAMQQFHNPATAMSMMQMAAMGLSPLGLMNLQPPLVPMMMAPPPPPPPAQSQPPATHSPSPSDQLAAAAAAANSLFSPAGLLVAKQQALLQQQQHLPHVPQHHHMASQLQQQQQQQQQQQKRARTRITDDQLKILRAHFDINNSPSEEQIAEMASRSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVSPLNPEEQKELFSQVVQAQQSSSNKRKQSQPIQAPQPPPVSPPPQQQMERISAESSLMGYKPSEDQYGGDDLSRSVKMELDEDVKPIINLTEENTRDEPDSPASMNVPTSIGTQIGNSLGVPLNIPTTSSRNISPGNLTLTSIIASQLGSQAEGIPVAPVTSSSTSPHAVSGGGAASANILAPPKAAPCATIYSSPVQSQVPPSPTSIMGVTLSNTPTSVVSGGGMMGMSTPVSTLSPGRSPSSSMDCMTSVGGGSGGSGSSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPPVEATAGVEGAGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSSVAESRGVADLSSVSTPSVPPPPPPPPPPPPPPPPPPPSFVSAMAPSPPTPDGRKSAQPAEASPPPTPSQSHGGHQEASEDSFQCDKCNLVFPRFELWREHQLVHIMNPNLFPSYPPDSPFGILQQHAQMQQQQQQQQQQQQQTQQNPQLHPASGHQHLGGISGAAVAAAAAAAAAAAGLSYEAGMGTLSPPIGQGKRKFDEVEEELRSGGEENAAPKDKRLRTTILPEQLDYLYQKYQVESNPSRKMLESIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLASKHADQVAARGGDVNIDALPDEELSVDSSASFSTTGDAQGGAAPGNTTPGGGKAGTGGMLSSAFPGAASMMQHNMISPLFSPFAAAAAAAAASQDAENSLKKFYEESMKRYISEMQSQAAQNGIPAVSGSAAAGGAVPATGSGGTAGGATGGGSGGTSGAAPATPAKESHGATDLSMKIKQEMGQSPAEATSDAPLDLSKPVDLSRPVRISTEAGGADQGPLTDISERSGSDARSDSLSETCTDNMDGDESNPTSPASSTQSQRHQTTAAGTPGAGTPLSGGSGAGSGKRFRTQMSSLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01212546;
90% Identity
iTF_01212546;
80% Identity
iTF_01212546;