Basic Information

Gene Symbol
Zbtb41
Assembly
GCA_933228905.1
Location
CAKOGJ010002742.1:48650-88589[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 3.8 2.7e+03 2.1 0.2 3 19 197 213 197 215 0.90
2 23 6.6e-05 0.047 17.1 2.7 3 23 261 281 259 281 0.95
3 23 0.49 3.5e+02 4.9 0.0 2 21 411 430 410 431 0.93
4 23 0.037 27 8.4 2.7 1 23 517 540 517 540 0.95
5 23 0.0017 1.2 12.7 0.3 2 23 547 568 546 568 0.95
6 23 0.048 34 8.1 2.8 1 23 574 597 574 597 0.91
7 23 0.3 2.1e+02 5.6 0.3 1 23 603 626 603 626 0.92
8 23 0.055 39 7.9 0.1 1 21 633 653 633 654 0.94
9 23 7.3e-06 0.0052 20.1 0.4 1 23 662 684 662 684 0.97
10 23 0.0079 5.6 10.5 2.1 1 23 690 713 690 713 0.96
11 23 0.0069 4.9 10.7 2.8 1 20 719 738 719 741 0.94
12 23 0.0024 1.7 12.1 0.1 3 23 749 770 747 770 0.97
13 23 0.0006 0.43 14.1 3.3 3 23 953 973 951 973 0.95
14 23 0.00026 0.18 15.2 4.3 2 23 1184 1205 1183 1205 0.96
15 23 0.27 2e+02 5.7 5.2 1 23 1361 1384 1361 1384 0.93
16 23 0.29 2.1e+02 5.6 0.1 2 23 1391 1412 1390 1412 0.95
17 23 7.5e-05 0.053 16.9 2.3 1 23 1418 1441 1418 1441 0.94
18 23 0.0056 4 11.0 0.3 2 23 1448 1470 1447 1470 0.96
19 23 1.5 1e+03 3.4 3.0 1 10 1477 1486 1477 1496 0.81
20 23 0.0053 3.8 11.1 0.1 1 23 1506 1528 1506 1528 0.96
21 23 0.00015 0.11 15.9 1.2 1 23 1534 1557 1534 1557 0.97
22 23 3.3 2.4e+03 2.3 0.8 3 19 1706 1722 1706 1725 0.89
23 23 0.00059 0.42 14.1 3.3 3 23 1771 1791 1769 1791 0.95

Sequence Information

Coding Sequence
ATGATCTGCCACTCATGTTTGTGTCGTCTCCACGAGTTTCAGCGCTTCAAGGCTCAGTGTATGAGAAGCAGGCTGGTGTTGGACGGTGTGTTGGAGAGCGGAGCAGACGTACATCCTGCCTCGGAGGGCAACAGGAAACAGACTGCTCTTAGGGGAAGGGAAGGGTGTAGAGGGGGGTTCTCGGAAGGTCTGCTAGCACAGATGCTGTTGCAATCACTCCTATTGGCAGAGTCAGCTGTGTGTCCCCCCCCCCCCAATAGCGATGAGGCGAAGGGGGGGGACACAGCTGACTCTGCCAATAGCAGCAGTTGTGACAGCATCAGTGCGAGCAGACCTTCCGAGAACCCCCCTCCACTCCCTTCCCTTCCCATAAGAGCAATTGAAGAAATAAGATCCGCGGAAGATGTAGCGAACCAGCCGGATGGAGGAAGGGAGAGAAGCATCTGTTCGGTGGCCGAAGATGCGGACAACAATGTCCAGAATCCATTCCACATGACCACTGAGGTGTCCAACCACGGTTCTACTTTGGTTTCACGAACAGAAGAGGACGGAGGTGATGGCGGAGACGTGATCATGGAGTATTGTTGGTGTAATGAGTGCGGTATGGAGTTCCTAAGCCACCGAGACCTGAGGGGTCACTGGGATTGGTGCGGGGGAATGCGGAAGTGTGCGGGATGGAGCACAATCTCGGAAGAAGGTCAACCAGGGGAAGGAACTGATGCGGTTAATGACTTCTCTATCGAGAGCACCAGCGGGCCGTTGTTCGACCCAAGCATCTGCTGCGGGAGTTGTCGTAAGGTGTTCAGGACAAAGGAACAACTGATACGACACATAAACAAGCATGACTTCAAGTGCAAAGCGAAGGTCTCCCGCAGATCTTTGACTATGTCCAAGGTGAACGAATTGGACTTGGTTCATTCACCGAACACCATGTTAGGGGAGCGTGGAGTGAAAACACCTCCAGCACCTTTAGGGAGGAACACTTGTGAGATTGTCTGTGTCAATCGTGTCCAGTGTGGACAGAGTTGTCAAAGTCAAGATCCTTCCGGATGCAGCAGCAAGAAAAAGTGCAGCCGTGGTAAGAAAGAAGTTTCCGCACTTGAAGAAAATATGTTTGTGGACGAGAAACACGTTGAGGAAGTGTCAGCGAAGTGTAACGGGAATGGAATCTCGAAGTATGTAAATTCTTCCAAGTCAAATCATTTGAAAACTGATGTTAGTGCTCAATCAAGCTGCCCAGCTTGCGGATTGATCTTTGAGAGCATTGACCTCTTGGCAGTGCACAGAAATGAATGTATTGTTGGAAACGGTGATCGTGTTGATGGTGAAAGTTTGAGTGATATCGGGCGAGGAGGGTCTGATGAACCTTCTCACGGAATAAATCCTGGTGAACAAACCATTGATGTGACGGTTGAAGGAAGCATTCCATCGAAACCAAATGGTGAAACTGCTGGTGAGGAAAGTGTTCTGGTGCCAATTGTTATTCAGTCGCAAACGTCTCGTGTCATTGTCGATGGCAGGGAGGATGATGAGGTAGATAACCCGTTTTACATCTGCGATTACTGTGAAAAGTCCCACGTGACCAAACCAGACTTGAGGAACCACATCGTCAAGTGCCACCTGTGCATCGTTCCGCAGAAGTGCCCCGTGTGCCATAGATTGTTCACGGATGATGAAGAGTTGGAGGAACACATGGTTTTACACCCGGAGGACAGGAAGTTCTTCTGCACAGTTTGTGAGGAGAGTTTCCACTTCAGGACTTCGATGAAGCGGCACATAGTCGAACGGCATAATGTCGACAGGGGATATATTTGCAGCATGTGCTCCAACGGATTTGCATCCCGGGCCGACCTTGGCTTGCACCACACCTACGCGCACCAAGACTCGGAGAAACGCTTCAGGTGTACGGCTTGCGGGAAGTCGTACGTGGTGAAAAAGGTGTTCGTGGCACACTTGAAACTTTGTCAGTTCAAGTCGGTGGTGTTCCGGTGTCACGTTTGCGGCAAGGAGCTCAGCTCGAAGGGCAATCTTGAAGCTCACCGCGCAGTGCACTCAAATGTGAAGAAGTTTGCGTGCACGATGTGTGAGAAGGCCTTTTCAAGCTGCAGGGCGAGGAATATCcacgtcagaagtttccacttgaagattaggccgcacgagtgcgtaatctgtcgaaaaaacttcCCCACGAAGGCAGAACTGAAAACGCACTATGCCTGTCACTCGGATCTGCGTCCATTTGGGTGTCCAGGCTGCGCGAAGACTTACAAAGCAAAAGGAGTACTAACTAAGCACATTCGTATATGGCATCCAGATCTTTTAATTGCTCCTCCCTCTGTCAAACCAGAGAGTGTACCTTCAAGCGCTCTGCTCCCAACCGGAGAGGTCGCTATGAGGGTTCTGTTCCGTAGTGGAGCGAATGAATTGATTGTTGCTCCGGAGCGGAGTGGTAAGCCCCTACGAACCTCTTTGGAGGGGTGCAACAATGATATGGAAGGAGTGCGGTCGATGGATTTTGGAGATGGCCAATCAGAGAAAGGCTCTGCTAAGGACCTGTTGGCGGTGGAAGGGAGCGGGAAGAGTGCCGTTGATCAGTTCTGTGGAATGGAAGGGCTATCATTGGTGGAGGAGGACTTGGAGGTGGAGTATTGTTGGTGTGCTGAGTGCGGAGTGGAGTTTCTGAACCATCTGGAGCTGAAGGGTCACTCGGAATGGTGCAGCGGCAGGGGGGGGAATGACACCACTGGATGGGGTCCAGTCTTGGGAGAAGGTCACATTGTTGAGAGTCCGAGGGTGGTCAATGACTGCTCCCCCACTGAGGTCACCAGTGTGCCGTTGTTTGACCCCAGCGTCTGCTGCGGGAGATGCCGAAAGGTGTTCAGGACTAAGGAGCGACTGATCCGACACATAAACAAGCACGACTTCAAGTGCGAAGCGAAGAAATCTCGGGTCGGAACAAGTGGAGATGAGTTCATTGAGAGGGGAAGGCCTTTAAGCCTCATGGATGCATCTCGGGGAAAGCAAGGACCAACTTTGAAAGGGTGCGAGCCCGAAACGAAATCAAATCTTGGTTGCCACGTCTACGGGAAAATTTCCGTCAATCATGTACACACTGAAAGTCACATGAATGAAAACAATTTAAACAAGGGAGTAGGTTTAGGAAAGAAAAAGGATGAGAAAAACCAGCCCTGCTCAATGGTCAACGCGAAACCTACTAAAGTTTCAGTGGCACGAGCAACGGACATTGCGGTTAAGAGTAAAATCAATTCTATCATTGCAAATGATGATGTTATGCGTGAGGAACGAAACGCTGTTGCCAAAGAGAGTTGTGTTCAACGGAACACTAATCTGCATTGTTCTTCAAATGAGCTCAAGACTGACTCCAAGTGCAAAGCGAAGGAATCCCTAGGTTCGTTGAATCCAAGCGAAATGATGTGTGTTGAGTTGGTAGAAATGGAGAAAGATTCATTTAACGGCATCCACGGTACAAATACAAATCAGCTGGCTTTGTCATTAAAGGAAAATGAACGCAAAGGGAAATCTCGTTTGACTTGTGATGTGTGCAGTAAGAGTTTCACCACCCATAAAAGCTTTCAACGGCATGTAAGTAAGCACAACGTAAACACCGAATTGATAGATACTGGGGACCCAAACAGTGGAGTCGATGAGGAGTATTTAGCTGGAGCAGTTGCAAAGTTAACGGACCAGGATTTCAATTCCATTGGTCAGAATTTCTCCCAATCCGGGGAATCTAGTCTGGGTGACACGATCAACGACTCGGAACTGTGCCAATCATTTAGTTACTCATCATCGTTGAAGGAAAATGCTTTGAAACGGCCCTCGAATAATTACAACTTGCGCAACAGTGGAAAAGCAGCAGGTTTACCGCTAAAATCAGGCAAAGAATCGGTGAATCCCAGAGCATTAGTGCAAGGAGATGTCGATGATCTGGACAGGTCAGTAAATATTGGTGGAGGGGAGGCAGTTTTAGTGCATGGCAGTGAACCTGAGGACTGCACACTGGAAATTAGTGATATAAGCACCGGTGATGGGATATATAAAGGGAAAGAAGAGTTATCGTATTTGTGTGATCACTGCGGAAAGCCACACAGCTCTAAACTGCAGTTGAGAAACCACATTGTCAAATGCCACCTGTCCCTCGATCCACAGAAGTGTGCCGTGTGCTACCGATTGCTCATGAACGCCGAAGAATTGAAGGCACACATGAGTTTACACCCAAAGGACAAGAAGTTCTTCTGCACGATTTGCGAGGAGAGTTTTCGCACCAAGTACGGGCTGCGGGATCACATGATCCACACGCATGGTATGGCTGGTGCATTGGTGTGCAGTATATGCCACAATGGTTTCCGGTCGAGGGTGGAGTTGGGCGTTCACCAGTCCACCGTTCATGCCAGGGCGGAAAAACGCTTCAGCTGTGAATTGTGCGGTAAATGTTTCCTGGCGGAGCATTTCTTCAAGAACCACGTCGACATTTGTCAGGCAAAGCGCTTCAAGTTTGTGTGCCAGGAGTGTGGGTTGGTGACGCAGTCGAAGTGGGACCTGCAGGTCCACTCTCTTATCCACGAGGGGATCAAGAAGTACGCTTGCACAATGTGTCCCAAGACCTTCACCCAGCACGGAGCGAGGAATTCCCACGTTAGGACCGTACACCTGAAGGTTCGgcctcacgaGAGCAAGCATGTGAGCGAGAAAGGACGCGTCGGGGAAAGTAGGCCCGAGAATCCACGAGAAAGGACACGTCGGCGGAATAAGACCGGGATTAAGATGGACGCCTCGAGAGCAGGACACATCGGGCAGATTAAGGAGCGGAGGCAAAGAAAGGAGATCGACGGGAGACGACGGAGAGGTGCATTCGTAGTAGTACGAGTGAAAGCGAGGAGACGTTGGCGGCAGGAGTCTGATACGGCAAGATGCACTCCGGCCCGATCTCACGGAGGGAGAGATTGTCAAGTCGAGGGAAGCTCTCCAATGGATCCTGTGCAGACGGAAGGATGTATTGGACATGCCGTTGATCAGTTCTGTGGAAACAAAGTGTTATCCTCGACAGCGGAGGTGATGGAGGAAGGGGAGGACTTGGAGGTGGAGTATTGTTGGTGTCACGAGTGTGGAGAGGATTTCCTGAACCACCGAGAGTTGAGGGGTCACTCGGAACGGTGCAGCGGGAGGGGGAATCACAAGAGATGTGGTCCAGTCGTGGTAGAAGGTCGTATTGTTGAGAGTACAAGGGTGGTCGATGACTGCTCCCCCATTGGGATCACCAGTAGGCCAATGTTTGACCCCAGCATCTGCTGTGGAAGGTGTCGAAAGGTGTTCAGGACAAAGGAGCGACTGATACGACACATAAACAAGCACGACTTCAAGTGCGAAGCGAAAGAATCAACAAGAACAATGAATGAAGCAGTTCCTTTGTCCACTAACCATATGCACACCATGCGCAGAGCGTGTGCGACGCAGCAGTTGCGTCCGCTAAATTCCATGCCTCTAGCGTGA
Protein Sequence
MICHSCLCRLHEFQRFKAQCMRSRLVLDGVLESGADVHPASEGNRKQTALRGREGCRGGFSEGLLAQMLLQSLLLAESAVCPPPPNSDEAKGGDTADSANSSSCDSISASRPSENPPPLPSLPIRAIEEIRSAEDVANQPDGGRERSICSVAEDADNNVQNPFHMTTEVSNHGSTLVSRTEEDGGDGGDVIMEYCWCNECGMEFLSHRDLRGHWDWCGGMRKCAGWSTISEEGQPGEGTDAVNDFSIESTSGPLFDPSICCGSCRKVFRTKEQLIRHINKHDFKCKAKVSRRSLTMSKVNELDLVHSPNTMLGERGVKTPPAPLGRNTCEIVCVNRVQCGQSCQSQDPSGCSSKKKCSRGKKEVSALEENMFVDEKHVEEVSAKCNGNGISKYVNSSKSNHLKTDVSAQSSCPACGLIFESIDLLAVHRNECIVGNGDRVDGESLSDIGRGGSDEPSHGINPGEQTIDVTVEGSIPSKPNGETAGEESVLVPIVIQSQTSRVIVDGREDDEVDNPFYICDYCEKSHVTKPDLRNHIVKCHLCIVPQKCPVCHRLFTDDEELEEHMVLHPEDRKFFCTVCEESFHFRTSMKRHIVERHNVDRGYICSMCSNGFASRADLGLHHTYAHQDSEKRFRCTACGKSYVVKKVFVAHLKLCQFKSVVFRCHVCGKELSSKGNLEAHRAVHSNVKKFACTMCEKAFSSCRARNIHVRSFHLKIRPHECVICRKNFPTKAELKTHYACHSDLRPFGCPGCAKTYKAKGVLTKHIRIWHPDLLIAPPSVKPESVPSSALLPTGEVAMRVLFRSGANELIVAPERSGKPLRTSLEGCNNDMEGVRSMDFGDGQSEKGSAKDLLAVEGSGKSAVDQFCGMEGLSLVEEDLEVEYCWCAECGVEFLNHLELKGHSEWCSGRGGNDTTGWGPVLGEGHIVESPRVVNDCSPTEVTSVPLFDPSVCCGRCRKVFRTKERLIRHINKHDFKCEAKKSRVGTSGDEFIERGRPLSLMDASRGKQGPTLKGCEPETKSNLGCHVYGKISVNHVHTESHMNENNLNKGVGLGKKKDEKNQPCSMVNAKPTKVSVARATDIAVKSKINSIIANDDVMREERNAVAKESCVQRNTNLHCSSNELKTDSKCKAKESLGSLNPSEMMCVELVEMEKDSFNGIHGTNTNQLALSLKENERKGKSRLTCDVCSKSFTTHKSFQRHVSKHNVNTELIDTGDPNSGVDEEYLAGAVAKLTDQDFNSIGQNFSQSGESSLGDTINDSELCQSFSYSSSLKENALKRPSNNYNLRNSGKAAGLPLKSGKESVNPRALVQGDVDDLDRSVNIGGGEAVLVHGSEPEDCTLEISDISTGDGIYKGKEELSYLCDHCGKPHSSKLQLRNHIVKCHLSLDPQKCAVCYRLLMNAEELKAHMSLHPKDKKFFCTICEESFRTKYGLRDHMIHTHGMAGALVCSICHNGFRSRVELGVHQSTVHARAEKRFSCELCGKCFLAEHFFKNHVDICQAKRFKFVCQECGLVTQSKWDLQVHSLIHEGIKKYACTMCPKTFTQHGARNSHVRTVHLKVRPHESKHVSEKGRVGESRPENPRERTRRRNKTGIKMDASRAGHIGQIKERRQRKEIDGRRRRGAFVVVRVKARRRWRQESDTARCTPARSHGGRDCQVEGSSPMDPVQTEGCIGHAVDQFCGNKVLSSTAEVMEEGEDLEVEYCWCHECGEDFLNHRELRGHSERCSGRGNHKRCGPVVVEGRIVESTRVVDDCSPIGITSRPMFDPSICCGRCRKVFRTKERLIRHINKHDFKCEAKESTRTMNEAVPLSTNHMHTMRRACATQQLRPLNSMPLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-