Ppul052756.1
Basic Information
- Insect
- Plagodis pulveraria
- Gene Symbol
- ZEB1
- Assembly
- GCA_963890685.1
- Location
- OY982979.1:5402991-5459831[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00014 0.023 16.7 1.4 1 23 468 491 468 491 0.95 2 19 0.034 5.7 9.2 0.6 1 23 497 519 497 519 0.97 3 19 0.81 1.4e+02 4.9 0.7 1 23 523 545 523 545 0.88 4 19 0.0068 1.1 11.4 1.1 1 23 550 573 550 573 0.97 5 19 0.0021 0.35 13.0 2.6 1 23 579 602 579 602 0.96 6 19 2.6e-05 0.0043 19.1 1.2 1 23 641 663 641 663 0.95 7 19 1.5e-05 0.0025 19.8 0.3 1 23 669 691 669 691 0.98 8 19 0.0008 0.13 14.3 0.1 2 21 697 716 696 717 0.94 9 19 0.34 57 6.1 2.5 1 23 1037 1060 1037 1060 0.86 10 19 0.00092 0.15 14.2 1.0 1 23 1066 1088 1066 1088 0.96 11 19 0.034 5.7 9.2 2.3 1 23 1092 1114 1092 1114 0.98 12 19 3.9e-05 0.0065 18.5 1.0 1 23 1119 1142 1119 1142 0.98 13 19 0.00012 0.02 16.9 0.1 1 23 1146 1169 1146 1169 0.96 14 19 0.00086 0.14 14.2 1.1 2 23 1178 1200 1177 1200 0.90 15 19 0.62 1e+02 5.3 0.5 3 23 1228 1249 1226 1249 0.92 16 19 2.6 4.3e+02 3.3 6.0 3 23 1266 1286 1264 1286 0.93 17 19 9.3e-05 0.015 17.3 0.4 1 23 1292 1314 1292 1314 0.98 18 19 1.2e-05 0.0019 20.1 3.6 2 23 1320 1341 1319 1341 0.97 19 19 0.00053 0.088 14.9 0.1 1 23 1347 1370 1347 1370 0.96
Sequence Information
- Coding Sequence
- ATGAAGAGTCTATCTAAGAAAATGCCGCCATCAAGTTTAAGTCTGTGCCACAGGAAGAACTTTAAAGTATATGTCTTCCAAACATACCAACTCAACCCGTTATCTACAGTAGAAATAGAAGATTCTAAGTACCCTCATATTATAGCCATTGACATTCCTGAAGATGAGAATAACAGTGATTGCTTTGAAAATCAGTTACCTACAATTAGCAATGACAGTGAAAACAACGTAGAACCATCCATTGAAGTGAAACAAGAAATTGTAGAAGAAGAATTTAATAATACTATCAAAGTTTTGTTTGAGGAAGTTCAGTTAGACAACTTAGCTAGTAATTCTAATGAAATTGAAAGAATTTGCCACAGTGATGATGACAATGTTGACAGTGTCAATGAAATTGAAATTAGGAATTCAAGTGAACATGACTTAATTCCGATTAATGTAGTAACACCAAAGAATAATGCAAAAAAACGAAAGTTAAATAAATCAGAGCTTGCTAAAGATAGTGCTGTAACCAATAGAAAAGTAAAACGTAGAAATGAAAACCTAGACAAGAAGATATCAATGGGAGAGTTGAGACAGAGACTGGCAAAAAGATTCAGCAAATGTGGAGTGTTAAAAGACGAAGATGGCCGTGTGATTGACACCAAAGTTATAATGCATAGCTTGACCGAATTATCACTATCAGTACTACGGCAGCTGAAGAATCAAGTAGCAATAGgaTATAGCTCAGAGGAACTTCAACCAGAAGGTATAAGATTGCTTGCACaacttcataaaaaatactctaaCAGTGACTCAAATGCAATTGATAATCCCATCATAGAAATAACATCCCAAGAAACAGACAAAACCTCTGAAATTGTTACAGCTGACGTAGATATTGACACTTCCACTGatgaagataaaaaaattgttgatcCTTTAAGTGACGACGAAACTATAGCAAATAAAGTTGCTAGAAAAGTTGTGGCTCAGAAAAATGCGCCTGCGCAGTCGGATTTAGTAGAAGCAGTTAGTAACCTAAAGAAAAGAGTTCTAAGAAATAAGACCAAAGGTAAAATCTCTATCGAAGAGTTAAGAAGAAGGTTGGAGAAGTTTTTCAGTAGCGTTGGAGAGTTGAAAGATGAAGAGGGGACGGTGATAGACAAGGATCGGATTTTAAATAGTTTGGGTATACTGAGGTTGCTTATGTTAAGGCGGCTTAAAAAGCAATTCGCTCGGAGCCGGGgTATTATCAAAAAAGGTGTCACACCAGACGGCATGCGGCTGCttagtatattaaataaaaagttgtgTTCGAAGTACGTCAGCGGGTTCACAGTGGAACACCTCCCGGATAAGGAGAGCATACTGGAAGAGTTCTCCAAGCGGCAATACTACGAGCAGTACATCACTGCGGAGTACAAGTGTGAACAGTGCTATACAGCTTTTAGAAATAACAGGGAGCTGAAAAATCATATTGGGAAAACACATAATGACAAAAACCCGTACGCGTGTTTTGTGTGCAACACACGATACAGCAAGAAGTCGTCCATCGGCTGGCACTTGATAAAGCACAGAACTGTTTACAAATGCAAGCTGTGCCCCTTTGTCACTAACCAAAAaGGATCGATGATACCACATTTTAATCAACACAAGGGTGTTATGTACTCCTGTGAAGTCTGTGATGCTCAATTTAGGAGTAGATCAGGACAATATTTGCACATGCATACCGCACACCGagagaaaaacattttcatatgcCAAGTGTGCGGTAGAAAGTTTTCATCGGATTGCGGCCTGAAAATCCACTACAATAGAAAgcataagTGTACGAAAAAGGAGTCCAGCGTTACCGGGTTGAAAAGGCATTTTGGCGCTGAACATCCGAGCGAGAACTTCGAAGCGCAGTACATTGCTATGCATAGCGAGACGCACAAATATCTGTGTCACATCTGCGGCAGGGTGTTCTCGTCGTCAAGAGCTCTCGAAGAACACAAGAACTACCACACGGGCGCTCGTCCATACTCCTGCGATGTTTGTGGAGCTAAATTCACGAGGAAAGGAACATTGTCTACACATATAGAAAGCCACATGGTTCCTACTAAAGAATGCGACGTTTGCGGGAAGAAGTTCACAAGGGATATACTGCTCGCCAATCATATGAGTTCCAGAGAACCTCTGACCAACTTGTCTGCAAAAGTCCCATCGTCACACAGAAGCCTGAGCAATAGAAAGAACTTCAAAGTATACTCATATGAAGCACAAAAACTTAACAAAGTAGCCACATCTGACATAGCAAACTCGAAATACCCACATATTGTAACTATAGATGTGACAAAAAAGGTAATAAgacaatattcaaataaaacacttaaatctGACATTACTGCAAAGGTTAACATTGAATGTGAAGATGACCCAGAATCACCCAATACAGTGTCTGAGGATATTGCCAGTAAAGAATCAACCATTAAAGTTAAAGAGGAAGATGCTGAAGAAATTGACAATGCTAACGTTACATTAGTGTTTGAGGAAGTAcaagtagataaattaataattgacCCTGAAACacctgatataaaaaaatctgttgtcaatGAGGAGCCTGCGAATGAAAATGGTAGTGACAATGATGCGGACAATGGCTTTGATATTAAAGATGACTTAGTAAAAGAAAATGATTATGGATTTAACGATAATGAAGTCAAAGCTGAAGACACTAGTGAAGAtgaaatactaatattaaagaaaactaAGAAAGCAAAGACTAAAAGGAAAGAAACAAGGAAACGGAAGATGACATTATCGGAACTGGCTAAAATGGATTTAGATGCAAATTGTGCCAGTGATGCAGAAGACATTAATAAAGATGAGATAGTCCTTAAGAAACGGGGTCGTAAGATATCCTTAGACGAGTTGAGAAGGAGACTTGTTAAACAGTTCTCTCATTGCGGCAacggaataaaaatattatcaccaGCAACAGTAAAGATGTTGGCACACTTACAGAAGAAATACAGCAACGAATACTCCAATGTATTCACAGTAGAACATCTCGGGACACGACAGCAGATTCTGGCTGAGTTCGCTCAGAGGCAACACTATGAAAGTTATGTTTCTGCCCAATATAAGTGCGAGGAGTGTTTTACTGCATTCAAGTCTTACAAAACACTGTTGTTCCACAAGAAAGCTTCTCATAATGAAAAGGATActtttatttgtacaatatgcAACGTCAGGTACAGCAAACAGGCCTCGCTAAAATGGCACTATTTCTCACACAGGACTGTGTATAAGTGCAAAATGTGTCCACTGGTCACATATCAAAAaCATACAATGGTTATGCATTATAATATTCACGCGGGAATATCGTACAACTGCAAAAAGTGCGAGGCTACATTCAAGAGTAGATCCGGGCTGTACTTGCATATGAACACGGCGCACAAAACTCAGTTTGAGTGCGCGACGTGCGGACGAGGGTTCTCCACTGAGTACGGACTCAAAGTACATCTGTACATGGCACATCAgGAAGGCGAACTTGAGACATCTACGTGTGACATATGCGATAAAACATTCGACAACTATGAGAAGTACAAGCGGCATTTCGCCTATATGCACAGTGAACAAATGGACGTTATGAAGGCGAAGCGACCTAGGATCGAGAAAGGAGATAGGAAACATGGCGTTCGGAATATGTTCTGTCCCGTGTGTCAGAAGCACGTGAACACTGTAGGGGCGATGCGGTGGCACTTCAAAGAAGACCATCCTAACGAGAGCTTCGAGGTGCAGTACAGCGGGACTCACAAACATCTCTGTCACGAGTGTGGCAAAGGGTTCCATGCAATATGCGAGCTAAACGACCACAAGAACCTCCACACAGGCGAGAAGCCGTACTCGTGCGCGCAGTGCGGCGCTGCCTTCTACCGGAAACGGAACTTGACCCTGCACGTGTTACGTCACAACCCGCCCTCCAAGGAGTGCCAACTGTGCGGGAAGAAGTTCCGCAGCGGATCCAACCTGCATAACCATATGAAgACGCACAGCGGCGAGCGTCGGTATAAATGCGGCATCTGTCCGAAGGCGTTCCTCCACGCGTCCGCTCTTAGCGCGCACACGCGTGGCGTCCATAATCACATACGTCGAGTCAAGAAGAAATCAACTAAtcctatttattaa
- Protein Sequence
- MKSLSKKMPPSSLSLCHRKNFKVYVFQTYQLNPLSTVEIEDSKYPHIIAIDIPEDENNSDCFENQLPTISNDSENNVEPSIEVKQEIVEEEFNNTIKVLFEEVQLDNLASNSNEIERICHSDDDNVDSVNEIEIRNSSEHDLIPINVVTPKNNAKKRKLNKSELAKDSAVTNRKVKRRNENLDKKISMGELRQRLAKRFSKCGVLKDEDGRVIDTKVIMHSLTELSLSVLRQLKNQVAIGYSSEELQPEGIRLLAQLHKKYSNSDSNAIDNPIIEITSQETDKTSEIVTADVDIDTSTDEDKKIVDPLSDDETIANKVARKVVAQKNAPAQSDLVEAVSNLKKRVLRNKTKGKISIEELRRRLEKFFSSVGELKDEEGTVIDKDRILNSLGILRLLMLRRLKKQFARSRGIIKKGVTPDGMRLLSILNKKLCSKYVSGFTVEHLPDKESILEEFSKRQYYEQYITAEYKCEQCYTAFRNNRELKNHIGKTHNDKNPYACFVCNTRYSKKSSIGWHLIKHRTVYKCKLCPFVTNQKGSMIPHFNQHKGVMYSCEVCDAQFRSRSGQYLHMHTAHREKNIFICQVCGRKFSSDCGLKIHYNRKHKCTKKESSVTGLKRHFGAEHPSENFEAQYIAMHSETHKYLCHICGRVFSSSRALEEHKNYHTGARPYSCDVCGAKFTRKGTLSTHIESHMVPTKECDVCGKKFTRDILLANHMSSREPLTNLSAKVPSSHRSLSNRKNFKVYSYEAQKLNKVATSDIANSKYPHIVTIDVTKKVIRQYSNKTLKSDITAKVNIECEDDPESPNTVSEDIASKESTIKVKEEDAEEIDNANVTLVFEEVQVDKLIIDPETPDIKKSVVNEEPANENGSDNDADNGFDIKDDLVKENDYGFNDNEVKAEDTSEDEILILKKTKKAKTKRKETRKRKMTLSELAKMDLDANCASDAEDINKDEIVLKKRGRKISLDELRRRLVKQFSHCGNGIKILSPATVKMLAHLQKKYSNEYSNVFTVEHLGTRQQILAEFAQRQHYESYVSAQYKCEECFTAFKSYKTLLFHKKASHNEKDTFICTICNVRYSKQASLKWHYFSHRTVYKCKMCPLVTYQKHTMVMHYNIHAGISYNCKKCEATFKSRSGLYLHMNTAHKTQFECATCGRGFSTEYGLKVHLYMAHQEGELETSTCDICDKTFDNYEKYKRHFAYMHSEQMDVMKAKRPRIEKGDRKHGVRNMFCPVCQKHVNTVGAMRWHFKEDHPNESFEVQYSGTHKHLCHECGKGFHAICELNDHKNLHTGEKPYSCAQCGAAFYRKRNLTLHVLRHNPPSKECQLCGKKFRSGSNLHNHMKTHSGERRYKCGICPKAFLHASALSAHTRGVHNHIRRVKKKSTNPIY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -