Basic Information

Gene Symbol
-
Assembly
GCA_963932165.1
Location
OZ010642.1:16258046-16261301[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.2 1.1e+02 3.9 6.2 1 23 441 464 441 464 0.95
2 13 0.055 4.7 8.2 0.6 2 21 501 520 500 521 0.93
3 13 4.8e-05 0.0041 17.8 3.7 1 23 553 576 553 576 0.97
4 13 0.051 4.4 8.3 0.2 1 23 589 612 589 612 0.88
5 13 6.8e-05 0.0058 17.3 2.8 1 23 638 661 638 661 0.96
6 13 0.0084 0.72 10.7 0.8 1 20 667 686 667 691 0.92
7 13 0.0027 0.23 12.3 5.1 1 23 704 726 704 727 0.95
8 13 3.2e-06 0.00028 21.5 0.9 1 23 770 792 770 792 0.99
9 13 3.5e-07 3e-05 24.5 0.2 1 23 798 820 798 820 0.98
10 13 0.038 3.3 8.7 1.0 1 23 826 848 826 848 0.94
11 13 0.0033 0.28 12.0 4.2 1 23 854 876 854 876 0.99
12 13 2.2e-06 0.00019 22.0 0.9 1 23 882 904 882 904 0.99
13 13 2.4e-05 0.0021 18.7 1.3 1 23 910 933 910 933 0.96

Sequence Information

Coding Sequence
ATGCTGACGCTGATCCTGCTGACTCAGGAGGGACAGAAAATCGAGTTGAGCGTGCAGCCCGAGGACACTTTCGCGGATTTAAAGAGCCAGTATCCCGATAACGATGGCCTGCCGGAATCCCTCGAGTTGCTCATCACGAACGGGGCTAACGTGCCGGAAAACACGAAAATACTCGACTACGTCACCGGCAGCTCGCAAGAATGGTTCAGCGCAGATCGGAGCACGGATATCGATGACGATGCTGCTTGCTCCGTTGCTGTAGAGACACAAATAAGAGAATGTTGCGCTCAAGGCTGCTCAAACTCTGACACGACTACGCCAGGCAAGCCGTTCTTCCCTTTACCTACGGACCACAACCGgcTCTCAGGATGCCTGATTGAAATAGGCAGGCCAGATCTCTACAATCATGTCCTTGGATTGGCTGAAGAAAGTTCCCAAAAGTATTTTTTGTGCAGCAGTCACTATGGTCAAGAAGCCTCTTCTTTGCCTCCACTCTGCACTGCGGACCAGTCAGCAGTTTCCCTCCTAAAGCCCAGAAACGAGAGAATGTGGACAGAGACGAAAGACGAAACAGTATTGATCAAAGTGGAGGAAGAACCTGAACTTCCGGACGTCGATTCCGACGTCAAGGACTCCGTGCTCGAATTATCGGACGTAGCCGAGGACTTCGAGCATCCGGGAATCCTCTGCCGCTTGTGCGGCGAACCAACCGCCAATCCGATTCATCTTTACGCTTgggacgaggagagcgaggagtTCAGCCTCGCTGATAAAATAAACTTGTGCCTTCCCGTTatgATCACCGTCACGGATCCTCTGCCGAAGCAGATTTGCGAGGAGTGTCGAGCGAAGCTGAATACCTGCCACGAGCTCGCGTTGTCCTCGTTGCGGACCGAAGACAAGCTGAGGCATCTCCTGCGAGAGAAGAAGCTGTGCGTCAACGACACAACCGAACGTCAGTGTCCTCTGTGCCTCGAAGGAAGCATGCGAACTGTGAAAAAGAGCGGTATTTATCGAAGAGACGATTTGAAGAAGAATCTTAGCTGCTCGGCGAGCGTGAGCAAAGCAGCTGGTCCCTCGTCGAGCGAAGAGTTCGCGGCGTCCGAAAATTGCGGCGATTTGTCGCTGAGTGGAATAAATTTCCATCTCGTGGACGACAATTCGACTTCAGAATTAACTGCGCTGCATTCTGCGGAAGCTCATCTCGAAAATTCTCCGCCGCTACCCGAGCTACAATCGTCGTGTTCGAATCGCGCAGCGAAAATCAACGTTACATCCCTCCGCACCCACGAATTTCCCTCCGAGAGTCGGAACGCCGCGTACCACTGCGTAATCTGCGAACACACAAATTTCGCCCATCCCCACGAGCTCGAGTTGCACTATCGACGTCACGGTTTCCCCGCGGGGAAATTCGCCTGCAATTTGTGCCGCTACGAGTGCGAGGAGCTCGAGGAGGCCGCGGAGCACGTGAAGACCTGCAGACCCGAATTCTGGGAGATTCGTTGCGAGGCTTGCGGCGCGACTTTTCCCAGCCACGAACAGATGAACGATCATCAGTGTCGCAAAACGTCCATCGATCAGCATCAGCCCGATGAAAAATCGTGCGCGGTGTCGGCGTCGAAGCTCCCgaaaaggaggaagaaacagcCGATTCAGTACAGCtgttttttctgccagaagcAATTTTCGCGAAAGAAAAGTCTGAAGATCCACATATCAACCTCCCACGCTGAAGAAACTGAAAATCCGCCTTACGCCAGGTGCTACAAATGCAAGAGTTGCAACGAGGCTTTCGCTCGAGAAACCGACGCCGCATTGCACGTGACGCTTCGTCACCTGGGGCTCGTCGCGCCTTCGGACTGTCCGGCGTCCCAGGAATTCGCGCTCGAGGAGCTCACAATCTCGCGTCTCTACGTCTGCGAATTTTGCGAGCGTTGCTTCACGACGCCGAGTTCGCTTCACGATCACCGCGAGATCGATCACGGTAGAAGCCTTGAATATTCGTGCCTCACGTGCGATCGGATTTTCGCGTCTCACAGGCAGCTGGCGAGTCACAAGAGCGGCGAGTCTCACCACCGGCCGTTCAACGTCCTCGGCGTGGGGCAATTTTACGTTTGCAAATACTGCGACAAGACGTTTCTGCACTATTCGAGCCTCTCGAGTCACGTTCTTCAGCATCATCAGGAGATCGCGCCGTATCTCTGCCGTCCTTGCAACGTGAATTTCGAGACGTACCGGGAGATCGCGGTGCACCGGGACATCGCGCATCCTTACCAATCGAGCGTtcacgagcgcgcgaagcgatgCTACAAGTGCCAGTACTGCCAGAAGCAATTTAGTTACGAGGTCGCTCTAGTCAAGCACATCAGGATTCACACGGGCGAAAGGCCGTTCAAGTGTTCGATATGCGGCAAGGGATTCGCGCAGAGTTCGGGACTGAACACTCACGTGAAGATTCACTCGGACGTGAGGCCGTACGCGTGCCCAAAATGCCCGCGAGCGTTTAAGATAAAAGGCGACTGCGACAATCACGTGAAGCGGCATTCGGGAAATCGGCCGTACAAGTGCGAATTTTGCTCGAAAGCGTTTATGACTCAACACGTGTTCAGTCAGCATCGCAGGATACACACGAACGACAGGCCGTACAAGTGCGACGTTTGCGGCGAGGCTTTCCGAAGATCGCACGTGCTGACTGTTCACCGTAGAATTCACACCGGCGAGAAACCGCACGTTTGCGATCTTTGCCCGAAGACGTATCGGCAGCGCGGCGACCTCGTGAAACATCGGAAGGTGCAGCACGGGATCGCCACAGCCACGGCCGCGAAACTCGGTTACGTGGACAACTGCTCCGAGAATTCGTACGATTCTCTCGCCAAGTCGAGTGGGAAACTCGCGGACCGTAAGAGCGGGAATTCCTCGCTGCTTCTGCCGCTTTGA
Protein Sequence
MLTLILLTQEGQKIELSVQPEDTFADLKSQYPDNDGLPESLELLITNGANVPENTKILDYVTGSSQEWFSADRSTDIDDDAACSVAVETQIRECCAQGCSNSDTTTPGKPFFPLPTDHNRLSGCLIEIGRPDLYNHVLGLAEESSQKYFLCSSHYGQEASSLPPLCTADQSAVSLLKPRNERMWTETKDETVLIKVEEEPELPDVDSDVKDSVLELSDVAEDFEHPGILCRLCGEPTANPIHLYAWDEESEEFSLADKINLCLPVMITVTDPLPKQICEECRAKLNTCHELALSSLRTEDKLRHLLREKKLCVNDTTERQCPLCLEGSMRTVKKSGIYRRDDLKKNLSCSASVSKAAGPSSSEEFAASENCGDLSLSGINFHLVDDNSTSELTALHSAEAHLENSPPLPELQSSCSNRAAKINVTSLRTHEFPSESRNAAYHCVICEHTNFAHPHELELHYRRHGFPAGKFACNLCRYECEELEEAAEHVKTCRPEFWEIRCEACGATFPSHEQMNDHQCRKTSIDQHQPDEKSCAVSASKLPKRRKKQPIQYSCFFCQKQFSRKKSLKIHISTSHAEETENPPYARCYKCKSCNEAFARETDAALHVTLRHLGLVAPSDCPASQEFALEELTISRLYVCEFCERCFTTPSSLHDHREIDHGRSLEYSCLTCDRIFASHRQLASHKSGESHHRPFNVLGVGQFYVCKYCDKTFLHYSSLSSHVLQHHQEIAPYLCRPCNVNFETYREIAVHRDIAHPYQSSVHERAKRCYKCQYCQKQFSYEVALVKHIRIHTGERPFKCSICGKGFAQSSGLNTHVKIHSDVRPYACPKCPRAFKIKGDCDNHVKRHSGNRPYKCEFCSKAFMTQHVFSQHRRIHTNDRPYKCDVCGEAFRRSHVLTVHRRIHTGEKPHVCDLCPKTYRQRGDLVKHRKVQHGIATATAAKLGYVDNCSENSYDSLAKSSGKLADRKSGNSSLLLPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-