Basic Information

Insect
Pieris mannii
Gene Symbol
L
Assembly
GCA_029001895.1
Location
CM054827.1:6888779-6893471[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.2 1e+02 4.3 4.8 1 23 3 25 3 25 0.97
2 16 7e-06 0.00059 20.7 4.1 1 23 31 53 31 53 0.99
3 16 2.2e-05 0.0018 19.2 0.1 1 23 59 81 59 81 0.98
4 16 3.4e-06 0.00029 21.7 0.2 2 23 97 119 96 119 0.96
5 16 1.9 1.6e+02 3.7 0.2 9 23 146 161 142 161 0.95
6 16 0.25 21 6.4 0.0 3 23 212 232 211 232 0.97
7 16 0.04 3.4 8.9 0.1 2 23 246 267 245 267 0.91
8 16 4.8e-05 0.0041 18.1 2.6 1 23 275 297 275 298 0.95
9 16 0.008 0.68 11.1 0.1 1 23 303 326 303 326 0.92
10 16 0.00069 0.058 14.5 0.4 1 23 386 410 386 411 0.96
11 16 0.00016 0.014 16.4 0.1 2 23 460 481 459 481 0.96
12 16 0.048 4.1 8.7 0.0 1 23 489 511 489 511 0.98
13 16 5.7 4.8e+02 2.1 0.7 2 23 519 540 518 541 0.91
14 16 0.95 81 4.6 0.2 3 23 617 637 616 637 0.95
15 16 0.0046 0.39 11.9 0.1 1 20 645 664 645 667 0.95
16 16 0.036 3 9.1 0.2 1 23 674 696 674 696 0.96

Sequence Information

Coding Sequence
ATGCCGTTTCGTTGTGAATTTTGCGCAAGATTATTCAAACACAAGAGGTCCCGGGATCGCCACGTCAAGTTGCACACTGGTGACAGAAAGTATCGCTGCGCACATTGCGAATCCGCATTCTCGCGAAGTGATCACCTGAAAATTCACATGAAGACACATGACAACCAAAAGCCATTCCAATGTACGGTGTGCAATCGGGGGTACAATACAGCGGCAGCTCTGACCTCTCACATGCAGGGTCACAAGAGAGACAGAGATGGGCGGGAGGTTGACCGTAAAAGGGCACTGAGATGTGTCCGATGTGGAGAAACATTCCGACGACCAGATATGTTACAAGCGCACATGACGACAGCCCACGGTGACATAACTCCACCTCGCCGAGTCGCTTCGCAACCACCACCCACACTCCTAGCTTGCATTTATTGCACACGTGACTCCTTTACTAGCATGGAGCAACTGCAACTTCACGTACGCTCATCACACTCAGCACTGTTAAATGGCGAAGGCCCTGTAGATCAACCAGCCCCTACAGATCTCAGTCGACGCGGGTCCGACGAAACGCCACCAATGAAAAGGCCACGATCAAGTGCAAGCGTCATTCCCCAATCGGTATTATCACCAAGTACTTTGTTGTGCAATCAATGCGATGCTGCATTGCCCGATTTTGAAGCCTTCCGCGCGCATTTGAAGGGACACCTCGAAGAAGGAAATGATATAAGTAAATCAGGACCCACGCCATGTTTGCATTGTGGCGCTACATTCACAGACCCAGTGGCATCAGAAAGGCATTTGGCAGCTCATTACTTAGCTGTGTCTTGCGAGTACACGTGTAATAGTTGCTCCCGAAATTTTTCAACACCAGATGATTTACAGAAACACTTATTTGAACATCATGCGCACAGTCTATACCGTTGCACCCTGTGCAAGGAAGTCTTCGAATCCAAAGTTGCTATTCAGGTCCACTTTGCAGTAGCTCATAGTGGGGAAAGCAAAATTTGGGTTTGCCGTTCATGTGGCACCAACGGTGGCGCTTTGCGGTCTGAAGCAGAATGTACTGCCCACGTACGAAATAGGCATGCTGCAGCAAGATGTGCATGTGGGGCTGTGCTGGCTGGAGCCAGGGCCTTAAGAGAACACGCAGCAGCCCACCATACGTATAGATGCCCTGTACCGACCTGCTCTGATACTTTTGCTGTTCAGTATTTGCTGGAGCGACACATGCAAGTCCATCATACTATTCCTCAGgaTTTAAATGGTGATTTATCGAGAAAGCGTTCTGAAAATAACAACGCCGTGGAAGAGCCATGTTCGCCGTGTATCACGGGCGAAAACCAAGGAACGGAAGAGCGACGTCGTAAGAATGGGGCAGTGGCGTTGCAATGTGCATATTGTGGGGAGCGAACGCGAAGTAGAGCCGAACTAGAAGCCCATACGAGGGCTCATTCTGGAACAACTGTTGCGAGACACAAGTGCCTGATTTGTGATGAAGTATTACCTTCCGCTGCCGTGCTTGCTGAACATAAGCTCACGCACTGCAAGGTGGTTGCCGGTGACACCTGTGCAAGATGCCGTTCAAGGCTACCCTCTGAAGAGGCCTTTTTAACTCACATGGCTCGGCATCATCCAACTTTACCCGCTCCTTGTATTATATGCAGACAGACTTTAGCTTCGGAACCGGAGGCACGTCTTCACGCAAGATTCCATTTACGGCCCAATGAAGATGAGCAAAGATGCGCTATTTGCTTAAAAACCCTATCAGAGAGCGAGGCCGGTGAAGGTGTAAGAGCCTGTTCCTCGTGTTATGTAAGGCATGCTGCCCCAAGACCTCCTCCGCCGTCAGACAATGACTGTAGACTTTGTCGGCGAGCCTTAGAGTCTCCTACACGTCTTCAAACACATCTTATTGAACATACCTTCGCTGGCATTGGTTCTTTCAGTTGCTATCTTTGTTCTGCTGTATTCACGAGCGCAGCCGGTCTTCAAAGGCATTTGCCAGAACATCCAGCTGCTACAAGGCCCTATGATTGCGGCCGTTGCGGTCTGAAATTCTTCTTCAGAGCGGAGTTGGACAATCATGCATTAATCCACCTCGAGGAAGCTGAATTAGCTCAAAGAGCATTTTATGAAGCCTACGCCAGGGGTGCTGCATCAGCTTGGGTTGCGCTTCAGTCTGATACATCCCCTAAAACTTTGTCTTCCCCAGTTACGGAAGTACAAGTTAAACAAGAAAGTGAGGTTAAAGAGGAGAAGAATGATGAATACATTGAAGTATCTTCTCCACCACCTATTCCGCCAACGTCCACAGAATCTGTATCGCCTATAGTGAAACAAGAAAAACCTGATGAGGAATGA
Protein Sequence
MPFRCEFCARLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDRDGREVDRKRALRCVRCGETFRRPDMLQAHMTTAHGDITPPRRVASQPPPTLLACIYCTRDSFTSMEQLQLHVRSSHSALLNGEGPVDQPAPTDLSRRGSDETPPMKRPRSSASVIPQSVLSPSTLLCNQCDAALPDFEAFRAHLKGHLEEGNDISKSGPTPCLHCGATFTDPVASERHLAAHYLAVSCEYTCNSCSRNFSTPDDLQKHLFEHHAHSLYRCTLCKEVFESKVAIQVHFAVAHSGESKIWVCRSCGTNGGALRSEAECTAHVRNRHAAARCACGAVLAGARALREHAAAHHTYRCPVPTCSDTFAVQYLLERHMQVHHTIPQDLNGDLSRKRSENNNAVEEPCSPCITGENQGTEERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGTTVARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCARCRSRLPSEEAFLTHMARHHPTLPAPCIICRQTLASEPEARLHARFHLRPNEDEQRCAICLKTLSESEAGEGVRACSSCYVRHAAPRPPPPSDNDCRLCRRALESPTRLQTHLIEHTFAGIGSFSCYLCSAVFTSAAGLQRHLPEHPAATRPYDCGRCGLKFFFRAELDNHALIHLEEAELAQRAFYEAYARGAASAWVALQSDTSPKTLSSPVTEVQVKQESEVKEEKNDEYIEVSSPPPIPPTSTESVSPIVKQEKPDEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00430847;
90% Identity
iTF_00771246;
80% Identity
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