Pmel005241.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phyto melanocephala
Gene Symbol
ZEB2
Assembly
GCA_941918875.1
Location
CALNXE010000487.1:374314-377759[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00024 0.019 16.0 0.2 1 23 187 209 187 209 0.97
2 15 0.0001 0.0085 17.1 0.6 1 23 215 237 215 237 0.99
3 15 3.9e-07 3.2e-05 24.7 0.8 1 23 296 318 296 318 0.98
4 15 2.3e-05 0.0019 19.2 0.6 1 23 427 449 427 449 0.96
5 15 0.00012 0.01 16.9 5.3 1 23 455 477 455 477 0.97
6 15 1.1e-05 0.00089 20.2 0.6 1 23 495 517 495 517 0.98
7 15 0.00075 0.062 14.4 0.2 1 23 526 549 526 549 0.95
8 15 0.00014 0.012 16.7 1.4 1 23 555 577 555 577 0.98
9 15 0.00011 0.0089 17.0 5.0 2 23 584 605 583 605 0.97
10 15 1.6e-06 0.00013 22.8 2.5 1 23 611 633 611 633 0.96
11 15 0.0065 0.53 11.5 2.0 1 23 639 661 639 661 0.99
12 15 0.00037 0.03 15.4 1.6 1 23 667 689 667 689 0.94
13 15 6.9e-05 0.0056 17.7 3.4 1 23 695 717 695 717 0.99
14 15 9.9e-07 8.1e-05 23.5 1.2 1 23 723 745 723 745 0.99
15 15 3.3e-06 0.00027 21.8 0.9 1 23 751 773 751 773 0.97

Sequence Information

Coding Sequence
ATGTCTTGTGATTTCTTAAACAAATGTCGCACTTGCCTAGGTGCCTGCGATATTTATCACCAACTATTTGATTATGTGGACGATAATTACAAAATCCTCAAAATGTTGAATGATGTAGTGCCGCAAATAGATATTAAGACCTCCTCGCAATATCCTACATTAGTGTGCCAGACCTGCGTGGATAAACTTCTAACCAGCTATAAATTTCAACAATTGTGTATTGAAACCAATAATCGTCTGCATGATTTGCTGGGTATTGCGGTCTTTGAGTCGCAGTCGAAATTGGCGAAAATATTGGATCCATTGACGAGCGTGTCTAGCTTTAAGATGGAACAAGAAATTAAAGAAGTTGCATGTTGTGGACGCAAAATACAACCAGATGAACTGCAGGATTCAATAGAATTAGGCAACGACTATAGACTTGGTGAAGCCGGAGGAAGTGGGTCGGATTCTAGCAATGAACAACTATCTCTTTTAAAAGAAAAATCAAAGAAAAAATCGCATTTAAAAGAAACAAATCCAGAAAAACCTGGAAAATGTAATCGTATAAATGGCAATTTTCCTTGTTCCGAATGCGGAAAGGTATTAACAAGTTTAAATCGCCTTAAGAAACATACAGCTATACATGATAGAAAGCGGTCTTATTCATGTGAATATTGCAATACAAGATTTGTGGCAGAGAAAGCTTTCAAAGCTCATATGTTAACGCATAGCGGTAAAGATATTGTCCCTAAAAAATATTTAAAACAAAACGACAGTATTGAAAATAACCACGACTGTAGAGAAGTTTTAGAGGGCGAAGATTTTATAGAGGAAATTGAAATAAATATAACGCAAAATAACAATGAAAGTTTAAATTATAAAGATAAAAAGGAAACGCTAAAATTTCAATGTCCTGATTGTCCAAAAACTTTTAAGAAAAAAGCTTCACTATCAATCCATTATAAAGTGCATAAGAAAAACGATTTTGTTAGAAATGAATTGCCAGAATTACATGAAAATCATATTCAGCAGCAGATACCAACTCTAGAAATGGAGAAATTACCTGAAATTATGGTAAAAGAGGAATTCAAGCTTACACCACAAATAATTAAAGTACCCATGCTGGGTACTATTGATGATAATGGAGAATATTTCAATAACGATAATGGCGATGAGTCAAAAGATTGCACGAAAGATGAACTTTTTGAAATGCCTGCTGCAGAAGAATCTAAAAATATTGATTTCGTTGACACCGGCATAGGAGAAATAGAAAAGCCCAACAAACGTAATGGCAATTTTCCTTGTAAAATATGCGGCAAAATTTTTGATCGTCCTTTTCGCTTAAAACGTCACAGTTCTGTACATTCGATGACCAAGCCACACGAATGTGGTATTTGTAAACATCGTTATACCAACGCCCATAATCTTAAAGCCCACATGTTAAAGCATAAAAAGAAAATGGATAACTGCAATCTAAACTCTCAGTCACGTCCCGAAGGCTTCAAATGTCCGGACTGCCCACGACGTTTTGAAAAACAGGTCTCGCTCTCCAGCCACCGTCAAATTCATACACGCAACGCCTCCGATGCCAATTATCCATGCATGGTTTGTCAACGCAACTTTAAGTCTGTAAGTTCCTTAATCGAACACATTGCTAACAAACATCCCGAAGTTGAAAAGCACAAATGTGATCAATGTGAAAAGACATTCGTTTTAAATGCGCAACTATTGGAACATTTAAATCGCCACAAAGGCAACAAAAACCTGGTGTGCCTTATATGTGAAAAAGAATTCCGTCATACACATACTTTGAAGAATCATATGCGTAAGCATAGTGGTGAAAGTCCATATCTTTGTCAAAAGTGTGGTAAAACATTCCGAAGTCCGGGTAGTTTATGCCAGCACATGGAACGTCATACAGGTTTAAAGAAATTCCAGTGTCCAGAATGTCCTAGTCGCTTTAAGTGTAAAGCAGATGTTATCAGACATACAAAGACGCATTCAAATGTAAAGTCTCATGCATGTGATATATGTGATTCTCGTTTTACGACACCGTTTTCATTGCAAAAACACAAGCTTTTGCATACGGGCGAAAGGCCGTTTAAGTGTGATCAGTGTAGTATGACATTTACTATAAGCTTTCGCTtacgtcgccatatgcgcactcacactggagagaaaccctacaaatgcaaatactgtgaacgtgcttattcggaaagtggagacttaacaaaacatttgcgtacgcatgtgggcgaaaatacctatatgtgtgaTCAGTGTCCCAAAGCCTTTAAATATCAAGCAGAATTAAAGAAGCATCAATCTCAACATTATAAAATGGCCAAAAAACTACAACAACAAGCTGAAAAAATGCCCCAAGAAATACAGCAAAATGAAATAAGCGAACAGGCACAAGAGGAGCAATAA
Protein Sequence
MSCDFLNKCRTCLGACDIYHQLFDYVDDNYKILKMLNDVVPQIDIKTSSQYPTLVCQTCVDKLLTSYKFQQLCIETNNRLHDLLGIAVFESQSKLAKILDPLTSVSSFKMEQEIKEVACCGRKIQPDELQDSIELGNDYRLGEAGGSGSDSSNEQLSLLKEKSKKKSHLKETNPEKPGKCNRINGNFPCSECGKVLTSLNRLKKHTAIHDRKRSYSCEYCNTRFVAEKAFKAHMLTHSGKDIVPKKYLKQNDSIENNHDCREVLEGEDFIEEIEINITQNNNESLNYKDKKETLKFQCPDCPKTFKKKASLSIHYKVHKKNDFVRNELPELHENHIQQQIPTLEMEKLPEIMVKEEFKLTPQIIKVPMLGTIDDNGEYFNNDNGDESKDCTKDELFEMPAAEESKNIDFVDTGIGEIEKPNKRNGNFPCKICGKIFDRPFRLKRHSSVHSMTKPHECGICKHRYTNAHNLKAHMLKHKKKMDNCNLNSQSRPEGFKCPDCPRRFEKQVSLSSHRQIHTRNASDANYPCMVCQRNFKSVSSLIEHIANKHPEVEKHKCDQCEKTFVLNAQLLEHLNRHKGNKNLVCLICEKEFRHTHTLKNHMRKHSGESPYLCQKCGKTFRSPGSLCQHMERHTGLKKFQCPECPSRFKCKADVIRHTKTHSNVKSHACDICDSRFTTPFSLQKHKLLHTGERPFKCDQCSMTFTISFRLRRHMRTHTGEKPYKCKYCERAYSESGDLTKHLRTHVGENTYMCDQCPKAFKYQAELKKHQSQHYKMAKKLQQQAEKMPQEIQQNEISEQAQEEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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