Basic Information

Insect: Physocephala rufipes
Gene Symbol: topi
Assembly: GCA_963966595.1
Location: OZ016501.1:14272535-14275174[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.6e-05 0.0036 18.1 2.6 1 23 268 290 268 290 0.97

2 11 0.72 71 4.6 2.0 2 23 325 346 324 346 0.88

3 11 0.015 1.5 9.8 0.1 2 19 409 426 408 428 0.94

4 11 6.4 6.3e+02 1.6 0.8 1 20 436 455 436 457 0.85

5 11 0.034 3.4 8.7 1.6 1 22 477 498 477 501 0.90

6 11 0.8 79 4.4 0.2 2 21 516 535 515 538 0.79

7 11 4.5e-07 4.5e-05 24.1 1.9 1 23 558 580 558 580 0.95

8 11 0.0027 0.26 12.2 1.1 1 23 586 611 586 611 0.95

9 11 0.4 39 5.4 1.7 1 23 617 639 617 639 0.88

10 11 3.4e-08 3.3e-06 27.6 0.4 1 23 645 667 645 667 0.99

11 11 0.038 3.8 8.6 1.4 3 23 675 696 673 696 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.6e-05	0.0036	18.1	2.6	1	23	268	290	268	290	0.97
2	11	0.72	71	4.6	2.0	2	23	325	346	324	346	0.88
3	11	0.015	1.5	9.8	0.1	2	19	409	426	408	428	0.94
4	11	6.4	6.3e+02	1.6	0.8	1	20	436	455	436	457	0.85
5	11	0.034	3.4	8.7	1.6	1	22	477	498	477	501	0.90
6	11	0.8	79	4.4	0.2	2	21	516	535	515	538	0.79
7	11	4.5e-07	4.5e-05	24.1	1.9	1	23	558	580	558	580	0.95
8	11	0.0027	0.26	12.2	1.1	1	23	586	611	586	611	0.95
9	11	0.4	39	5.4	1.7	1	23	617	639	617	639	0.88
10	11	3.4e-08	3.3e-06	27.6	0.4	1	23	645	667	645	667	0.99
11	11	0.038	3.8	8.6	1.4	3	23	675	696	673	696	0.95

Sequence Information

Coding Sequence: ATGATGAATTCCACAAACCTTGGAAACGTtgaagattttcaaaattccgATGCGTGGCTCTCAGAGCAATTATTTGCTCAGTTAAAGGATTTTAATTCTGACTACAAAGCCAATGGCAATATCGAAAATTTAAGTCCATCTATGGACGTTAATGCCGACATAAAGGTTCGCTTAGAAGATTTTCAACCAGAATTAAGAAGAGATTCGCCGCACATTTTCGAAGCAAATACAGAAGTTTTGGATTTAAGCAATCTCATGGAGAAAGATAGTGACCGCAACGCGCTGTTGGATATGGCAAATGCCGAAACTGCAATGCGAATAGAGACTCAGCCGCCACTTAGTTTCGATGCCAGCGAAGAAGAaatgaagttattaaaatttttggaatctCAATCGAAAAACACTTATTTAGGTGaaaataaagtatGTATGCCGTCTGAACTTCCATCTTCAGCATATCGTATTATAAAGTGCTCAAATTGTAATTGTCTCTTCGATATTATATCATTCCAATCACACGTCTGTGATTACGATGagcataataatttaataatgccATCTTTAGCATCAACTGCCCATATTAACAGCAAACAACCGAAGGATGATTCGTTATTGGCGCCTGAACCGGCTTGTATTAGATTATTACGCGAGAATCAGATTCGTATTAGGCGTTTTCTCAAAGATGAACTAAAATACGACGTAAACGCTGCCTCAATATCCAACAGCAACTGTAGTAATGGACAAAATTCGATGCTTTCCAATCCAAATGTTTCTAATTGTAACAAAAAGCAATACGGCCCACATGAATGCACTCTCTGTGAGAGAAAATTTGTTCATGCTTCTGGTCTATTGCGTCATATGGAAAAGCATGCCATGGATTTGATACCAACTCCTGGTCTAGGTTCATGCGGTACAAAAGCATCTTCAGTATCAAGTTCATTGCATAATGTCAACGGGTTGCGCTTAGTGATCAAGTGTACACTTTGTGGACGTATATTTTTTGAGTTGTCTACATCATACAAACACTTGTGTGGACACTTCCCTGGCGGCTCAGAAGAAGAGTCGGAGATGGACAATTCGGCTGAAATTCCGTATGAAAGTTATGTGGATGATGCCTTGAACTTTCTTAGAATGGAGGCGAAGGCGAACACATTAAGCTCTTCACCATTCCAGGAGGATAAAACTCCCGTCTATCTAAAAATGGTTATACTCAGCTGCATATTACAATGCGAATTTTGTGATTATGTATTTTCTGAAGTGTCTTATTTATTTGTACATTCGGCTTGTCATTTACCGGAGCGTCGATTCGAGTGTTTCTCTTGTGATATCTGCATGCGTACGTCCAAGGAAATCTTCACGCACTGGCAGGCTGAATGTGTTTTCATGCGAGAAAATTTAAAGGTGCACCAGGCAACTACACAACGCTATTTTGTTTGCAATGTttgcgaaaataaatttcaatcattGGATCAACTGCATGAACATCGTTATACAGCTTATCACTTCTTTCCACGTTTGCACAAGAATCTTGGCGTATTGCAATTACCCTGTGAATATTGCGACGCGGTATTTGAATACGCGCAGGAATGTGTGGCTCACTATGAAGAGaagcattataaaaaatacaaacgtGATAAGGACGGAGCTGGATCGTCTGGCAAGACGCGCCAATATTTATGTGACATATGTGGAAAGTCCTACACGCAATCCAGTCATCTCTGGCAACATTTGAGGTTCCATCAAGGTGTCAAGCCATTTGCTTGTAAGGAGCCTGGCTGCACACGTAAATTTACTATACGTCCCGACTTAAATGATCACATACGCAAGTGTCATACTGGCGAGCGTCCTTATCATTGTCTTGTTTGCGGTAAACGATTTCTCACAGGCTCAGTTTTCTATCAGCACCGCCTAATTCACCGTGGAGAGCGTCGCTATGAATGTGAGGAATGTGGTAAACGATTTTATCGTGCTGATGCTTTAAAGAATCATCAGCGCATTCATACTGGCGAGAAGCCTTTCGGCTGCCTTTTTTGCACTAAGAATTTTCGGCAACGCGGAGATCGCGATAAGCATATTCGTGCACGTCATTCACATTTGGATGCGAATGCTCGTCTAATGatgcaaatgcaaaaattacaGTTGGAggccgctgccgctgctgcaGCAGCCGCAGCACAAGCGCAAGTCCAAAAACAACAGATTACACCCAATGGTGAAAGTCTAAATACGcttgttggtggtgttgaaGAACAAAATACAGATACTAATGATGTGGTTATAATTGGGAATGTCGCGTTTCCGAAGAGTATGTTTGAATCGATAATTCCTGATATAGACGAAGACGGTGCATTTAAAGCAATGGACATATCTTAA
Protein Sequence: MMNSTNLGNVEDFQNSDAWLSEQLFAQLKDFNSDYKANGNIENLSPSMDVNADIKVRLEDFQPELRRDSPHIFEANTEVLDLSNLMEKDSDRNALLDMANAETAMRIETQPPLSFDASEEEMKLLKFLESQSKNTYLGENKVCMPSELPSSAYRIIKCSNCNCLFDIISFQSHVCDYDEHNNLIMPSLASTAHINSKQPKDDSLLAPEPACIRLLRENQIRIRRFLKDELKYDVNAASISNSNCSNGQNSMLSNPNVSNCNKKQYGPHECTLCERKFVHASGLLRHMEKHAMDLIPTPGLGSCGTKASSVSSSLHNVNGLRLVIKCTLCGRIFFELSTSYKHLCGHFPGGSEEESEMDNSAEIPYESYVDDALNFLRMEAKANTLSSSPFQEDKTPVYLKMVILSCILQCEFCDYVFSEVSYLFVHSACHLPERRFECFSCDICMRTSKEIFTHWQAECVFMRENLKVHQATTQRYFVCNVCENKFQSLDQLHEHRYTAYHFFPRLHKNLGVLQLPCEYCDAVFEYAQECVAHYEEKHYKKYKRDKDGAGSSGKTRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPFGCLFCTKNFRQRGDRDKHIRARHSHLDANARLMMQMQKLQLEAAAAAAAAAAQAQVQKQQITPNGESLNTLVGGVEEQNTDTNDVVIIGNVAFPKSMFESIIPDIDEDGAFKAMDIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00366774;
90% Identity: -
80% Identity: -