Basic Information

Gene Symbol
-
Assembly
GCA_963966595.1
Location
OZ016501.1:16446386-16448823[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 3.2 3.1e+02 2.5 0.3 2 17 103 118 102 119 0.89
2 14 0.0022 0.22 12.5 1.0 2 23 297 319 296 319 0.93
3 14 0.00051 0.05 14.5 3.7 1 23 325 347 325 347 0.98
4 14 5e-05 0.0049 17.7 5.3 2 23 354 376 353 376 0.95
5 14 0.099 9.8 7.3 1.9 1 14 381 394 381 405 0.85
6 14 0.00038 0.038 14.9 10.4 1 23 410 432 410 432 0.98
7 14 0.00028 0.027 15.3 3.6 1 23 438 460 438 460 0.96
8 14 8.8e-07 8.7e-05 23.2 3.3 1 23 466 488 466 488 0.98
9 14 1.7e-05 0.0017 19.1 0.5 1 23 494 516 494 516 0.98
10 14 0.0015 0.15 13.0 5.4 1 23 525 548 525 548 0.97
11 14 0.00043 0.042 14.7 5.4 2 23 562 584 561 584 0.91
12 14 7e-05 0.0069 17.2 0.7 3 23 592 612 591 612 0.93
13 14 0.0008 0.078 13.9 2.2 1 23 621 643 621 643 0.95
14 14 9.8e-05 0.0096 16.7 2.0 1 23 649 671 649 671 0.98

Sequence Information

Coding Sequence
ATGGCCTTGGACTTTTGCTTTGACAGAAAGACATTCCTCGAGCAAATCTGTCGTGCTTGCAGTCGGTATTATAGCTacgatgacaatgatgatgaaaaaatggaattttttcgGATATTTGATGATGTCAAGTCTGAGCAAACCTCATACTCACTCGTCACAGTTGCAGATGTCATCAAAAATGAAGATGGCACCGCGGAGACAATGGGTAAGGTGGTACTACCGACTGAGGaggtaaaagaaatttttcaggAAATGGTAATTTGGAATTTAAACATTAAACCGTATGATGGTTTGCCACAACAAGTATGCAAGGATTGTATGGAACGCTTTCGCAATGTTAAGAATTTTCGAGAGGAATGCCTTGATACTCAGAAAGTTTTAGAATCGTATTTCAAAGATATGAATCAATTAGTAAGCAGATCCCCAAAATCGGAAGATTCAATCAAGATTGAACCTGGAGCTTCACCGGCTGCATCCTTTAATACCGATGATCTTGTTGAAGAAGTGCCCGAATCTCCGGCTGGGAATGAACAGTCGCCTATGTCCAGTCCACAGTTGCGTCAAAGTCCCAAAATATCTGATCAGCCTTATTATGCAGATAGCTCTATAGGCACACCGCCGCCACTATTCGAAGAAATCAAAACCGAACCGATCGATGTACAAACTATGGACTTTATTAAGACAGAGGAAGAGTTAAAATTAGGCCATAATCAGAAAGACGGCCTAGAAGCAGATAGCTATATCGATGAATTGAATGTAAAAGCTTTCAGTCAGGCAACGCTACCGTCTCAAACCTACATTAGTGACGAGGAAGATTCTTCTAGTGCATCCAATGATGAAACAGATTTACTCGAGTCAAATACTGAACAACAGTCGAATCAATTGCAATGTAAAATTTGCTTTCACATCTTCCCAACACAATTCCTATTGAAGGAACATCTCGCTAACCTGCATCCGGAAATAAAGTCTTATTCTTGCAATATCTGCTCGAGtacatttaaatcaaaatttaccTTAACGCAACACAAATTGAAGCACAATCGTCTTGATACTACACGATGTGAAAAATGTGGCAAATTCTTTCGTAGCCAGCTGCATCTTCAGCGTCATACAAAGAATTTCCACCTGACATCGACATACACGTGTCACATTTGTcatcaaaaatttgaacaataCACACAGATACGTTTCCAATATCACGTACGTCAGCACGGTGAGAAACGTTTTCACTGTCATTACTGTGACAAATCTTTTCATCAGAAAATTCATCTGGTAAATCACGAGAGAACACACACTAAGGAACAGCCATTTCAATGCGATATCTGTGGCAAATCATTTCGCCAGCAGACGGCTTGTCATGAACACGTTCTAACGCATTCAGATCCAAAACCGTTTAagtgtaaaatttgtaaaaaagGTTTTACACAACGCTCCAGTTTGCGCCTTCATTATCGTCTACACACAGGCAATAGACCATTCCGCTGCGAATTCTGCGGGCAGAATTTTGCGCAAAAAGTTCAACTTGAAATGCATGAAATGACGCACAGCAATGGCAATGCATATGCAAAATATCATTGtgaaatttgcaataaaaagttTCACATGCTTCATCAATTAACGACTCATATTGAAATGATACACAAAACAATTGATGTAGCTAACAATGCGATTGGACGTTGCATCTGTCATCATTGCAATGCCGCATTTACTAATCAAACACATCTGCAGTCGCACATTGAGGATGTTCACTTTCAAAAACGTCTACAAAGTTGCATTTATTGCGGTCAGACATTTTCACTTGCAGCTCATCTGAAGGCACACATGCAGAtgcacaacaaaaaaatcgTCTACGGGACTTACAAATGTCAATATTGTGATAAAAACTGTAAGAACGAACAAGCTTTGGAATTGCACGAAGAACAGCATGAACAATGCGAGCAATTTAAATGTAGTTTCTGTGGGCAGACATTTTTGTATCGTAGCACATTGAGAGAACATATGCTTATGCACTTGGGCGAGAATAAGACTACTAAATGCGATGATTCGACTACCTTCAGCATCGATACAagcattatataa
Protein Sequence
MALDFCFDRKTFLEQICRACSRYYSYDDNDDEKMEFFRIFDDVKSEQTSYSLVTVADVIKNEDGTAETMGKVVLPTEEVKEIFQEMVIWNLNIKPYDGLPQQVCKDCMERFRNVKNFREECLDTQKVLESYFKDMNQLVSRSPKSEDSIKIEPGASPAASFNTDDLVEEVPESPAGNEQSPMSSPQLRQSPKISDQPYYADSSIGTPPPLFEEIKTEPIDVQTMDFIKTEEELKLGHNQKDGLEADSYIDELNVKAFSQATLPSQTYISDEEDSSSASNDETDLLESNTEQQSNQLQCKICFHIFPTQFLLKEHLANLHPEIKSYSCNICSSTFKSKFTLTQHKLKHNRLDTTRCEKCGKFFRSQLHLQRHTKNFHLTSTYTCHICHQKFEQYTQIRFQYHVRQHGEKRFHCHYCDKSFHQKIHLVNHERTHTKEQPFQCDICGKSFRQQTACHEHVLTHSDPKPFKCKICKKGFTQRSSLRLHYRLHTGNRPFRCEFCGQNFAQKVQLEMHEMTHSNGNAYAKYHCEICNKKFHMLHQLTTHIEMIHKTIDVANNAIGRCICHHCNAAFTNQTHLQSHIEDVHFQKRLQSCIYCGQTFSLAAHLKAHMQMHNKKIVYGTYKCQYCDKNCKNEQALELHEEQHEQCEQFKCSFCGQTFLYRSTLREHMLMHLGENKTTKCDDSTTFSIDTSII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00366671;
90% Identity
-
80% Identity
-