Pruf017930.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Physocephala rufipes
Gene Symbol
sd
Assembly
GCA_963966595.1
Location
OZ016504.1:35609523-35651192[-]

Transcription Factor Domain

TF Family
TEA
Domain
TEA domain
PFAM
PF01285
TF Group
Helix-turn-helix
Description
The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and AbaA. The TEA domain is located toward the N terminus of eukaryotic transcription factors of the TEA/ATTS family. It shows a three-helix bundle with a homeodomain fold [3, 1]. Two α-helices are nearly anti-parallel and pack on either side of the third one, which is the DNA-recognition helix of the TEA domain. Phosphorylation of one or both of the two conserved serines found on the DNA-binding surface could interfere with DNA-binding activity, by introducing electrostatic repulsion and/or steric hindrance, and help regulate the transcription factor activity of the proteins [2, 1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.3e-09 1e-05 26.1 0.0 2 35 153 188 152 214 0.84
2 2 4.7e-17 3.7e-13 49.9 2.9 30 66 219 255 194 257 0.81

Sequence Information

Coding Sequence
ATGAATGAGAATAGTCAAGCGACTCTTACGATGTACGTTGTAATCAATTGCACGATGATATTTCGCCTCAACGGTAGTGGCGGTGGCGGAAGCGGTGGCGGTGGCGGTATTGGTGGCGTTGGTGTTAGTAGTATTATCGGTGGTAGTGGCAGTGGTAGTAGTGGAATGGTCGTCATCGCCAGCAACATTAGTAAAgacggcagtaacagcaatagcagcaccaatcacaataccaacaacaacagttacaacaccaacaacagcgcCTCGGAGGCATCAAAATTGAAagACGGGATTGTTGGTCCCGGCACCATAACGTCACCGTGGACGCCAGTAAGTGCCGGCCCCCCAGGGCCTTTGGGGCCGGCAGACACCAACGGCAGTATGACGGATAGTAAAAACTTGGATGTTGGCGACATGAGCGATGATGAAAAGGATCTCTCCTCGGCCGATGCTGAAGGCGTTTGGAGTCCAGATATTGAACAAAGTTTCCAAGAGGCCCTTTCAATATATCCACCATGTGGGCGacggaaaattatattatcgGATGAGGGTAAAATGTATGAAGTGAAACTATGCCAAGAATGTGCAATTAGTGAACGTCGAGAGACAGCAGCGCAGCGCAGCAAAGCAGCAGTAGCCGACCAAGGCAGCAAAGCAGCGCAGGCATCAAGACGAAACGAACTCATAGCACGTTATATCAAGCTTCGAACCGGCAAGACGAGAACACGCAAACAAGTTAGCTCTCACATCCAGGTCTTGGCCAGACGAAAGCTGCGTGAGATTCAGGCGAAGATAAAAGTTGAACCCGGCAGTGTTGTAAACGGTGAGATCGGCTGCAATATCCAAGGCAATGCTGTCCCCGGTCTTAGCGGGAAAGATAAAGCGTTACAGGCCATGTCTCGATTGACAAGCTCGCAAATTATTTCCGTTCATGCGGTCAAAAATCAACCTCTGACCGCAGCCAATGCAAGCGAGTTCGGGCAACAATCATCACCTCCATCTCCGCGTGCAATTCACGAGGATCATCTACGTTATCACCAACATCTGCAGGACCAACATCTTCAATATGAATCCCATCAGAGACATCAGTCACTGCATCATATGCACGCCCATCCCCACaaccatcaccaccaccaccagcagcagcaacaacaacaattggcTATCAGTCCACACGATGTACAGAAACTACATCAATCAGCATTGCCAGCGTATCGGCAACATTTGTCCGTAACGAAAGGGTTGACGTCAGTAACGACATTATCAGCAGGGTTGCCCCAATCTCGGATCACACATCATCCACCATTATACCCGGGTCAATTTTGGCAACCCGGTCTCCAACCAAGTACATCGCAAGATTTTTACGATTACAGCATTAAGCCCTTCGCCCAACCACCCTATCCCGCCGGCAAACCATCGACAGCTGTGTCTGGCGATATAGAAGCAGGTCTTCCGCCCGCGCAGCTTCCATGGGAGGGCAGAGCGATAGCGACGCACAAATTCCGGCTACTCGAATTTTCCGGTTTCATGGAAATCCAAAGAGACGATATCTATCACCGGCACTTATTTGTACAGTTGGGTGGTAAACCATCCTATTCCGATCCATTGCTAGAGACCGTTGACATTCGACAAATCTCCGATAAATTCCCTGAAAAGTCCGGTGGCCTAAAAGACCTCTACGAGAAGGGACCCCAGAATGCGTTCTATCTGGTGAAATGTTGGGCCGATTTGAATACCGAAATCACGGGCACGGAAACGGGCGATTTCTATGGCGTAACCAGCCAATAcgaaagtaatgaaaatgtgGTGCTTATCTGCTCGACGAAAGTCTGTTCGTTCGGTAAGCAAGTGGTCGAGAAGGTCGAAACCGAATACTCGCATTTGGAAAATGGACGTTTCGTCTATCGAATTCATCGTTCGCCGATGTGCGAGTACatgattaatttcattcagaaGCTAAAGAATTTACCTGAACGATATATGATGAATAGTGTCCTGGAGAATTTTACAATACTTCAAGTCATGCAAGCCCGCGAAACCCAAGAGACTCTATTGTGTATAGCGTATGTCTTCGAGGTGGCTGCGCAGAATAGCGGTGCCACTCATCATATTTATCGGTTAATTAAGGAATAG
Protein Sequence
MNENSQATLTMYVVINCTMIFRLNGSGGGGSGGGGGIGGVGVSSIIGGSGSGSSGMVVIASNISKDGSNSNSSTNHNTNNNSYNTNNSASEASKLKDGIVGPGTITSPWTPVSAGPPGPLGPADTNGSMTDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYEVKLCQECAISERRETAAQRSKAAVADQGSKAAQASRRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVEPGSVVNGEIGCNIQGNAVPGLSGKDKALQAMSRLTSSQIISVHAVKNQPLTAANASEFGQQSSPPSPRAIHEDHLRYHQHLQDQHLQYESHQRHQSLHHMHAHPHNHHHHHQQQQQQQLAISPHDVQKLHQSALPAYRQHLSVTKGLTSVTTLSAGLPQSRITHHPPLYPGQFWQPGLQPSTSQDFYDYSIKPFAQPPYPAGKPSTAVSGDIEAGLPPAQLPWEGRAIATHKFRLLEFSGFMEIQRDDIYHRHLFVQLGGKPSYSDPLLETVDIRQISDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTEITGTETGDFYGVTSQYESNENVVLICSTKVCSFGKQVVEKVETEYSHLENGRFVYRIHRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMQARETQETLLCIAYVFEVAAQNSGATHHIYRLIKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00366466;
90% Identity
-
80% Identity
-