Basic Information

Insect: Phymatocera aterrima
Gene Symbol: lola
Assembly: GCA_963170745.1
Location: OY720663.1:3080022-3108706[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00045 0.047 14.6 1.7 1 23 439 461 439 461 0.96

2 14 0.0054 0.56 11.2 1.4 1 19 479 497 479 505 0.96

3 14 1.3e-05 0.0014 19.4 2.4 2 23 507 528 506 528 0.96

4 14 0.0008 0.084 13.8 0.3 1 21 613 633 613 634 0.96

5 14 0.00024 0.025 15.4 4.8 1 23 642 665 642 665 0.96

6 14 0.099 10 7.2 0.1 1 21 719 739 719 740 0.93

7 14 2.2e-05 0.0024 18.7 0.4 1 23 748 771 748 771 0.98

8 14 5.9e-05 0.0062 17.4 0.4 1 21 830 850 830 851 0.96

9 14 0.0001 0.01 16.6 3.6 1 21 887 907 887 908 0.94

10 14 0.0019 0.19 12.6 1.8 1 19 956 974 956 977 0.96

11 14 2.4e-05 0.0025 18.6 0.6 1 23 985 1008 985 1008 0.97

12 14 0.0079 0.83 10.7 1.2 1 15 1035 1049 1035 1049 0.92

13 14 0.0068 0.71 10.9 0.4 1 21 1082 1102 1082 1103 0.94

14 14 0.038 4 8.5 2.9 1 21 1111 1131 1111 1134 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00045	0.047	14.6	1.7	1	23	439	461	439	461	0.96
2	14	0.0054	0.56	11.2	1.4	1	19	479	497	479	505	0.96
3	14	1.3e-05	0.0014	19.4	2.4	2	23	507	528	506	528	0.96
4	14	0.0008	0.084	13.8	0.3	1	21	613	633	613	634	0.96
5	14	0.00024	0.025	15.4	4.8	1	23	642	665	642	665	0.96
6	14	0.099	10	7.2	0.1	1	21	719	739	719	740	0.93
7	14	2.2e-05	0.0024	18.7	0.4	1	23	748	771	748	771	0.98
8	14	5.9e-05	0.0062	17.4	0.4	1	21	830	850	830	851	0.96
9	14	0.0001	0.01	16.6	3.6	1	21	887	907	887	908	0.94
10	14	0.0019	0.19	12.6	1.8	1	19	956	974	956	977	0.96
11	14	2.4e-05	0.0025	18.6	0.6	1	23	985	1008	985	1008	0.97
12	14	0.0079	0.83	10.7	1.2	1	15	1035	1049	1035	1049	0.92
13	14	0.0068	0.71	10.9	0.4	1	21	1082	1102	1082	1103	0.94
14	14	0.038	4	8.5	2.9	1	21	1111	1131	1111	1134	0.96

Sequence Information

Coding Sequence: ATGGAAGACGACCAACAGTTCTGCCTTAGATGGAACAACCACCAAAGTACActtatacaaaattttgacacACTTCTTGAAAGCGGCACATTAGTTGACTGCACTTTGGCAGCGGAGGGGAAATATTTAAAGGCCCACAAAGTAGTCCTCTCCGCGTGCAGTCCATACTTTGAGGGCCTCCTCAGCGAACACTATGACAAACACCCAGTATTTATACTGAAAGATGTTAAATTTAAAGAGCTCAAAGCCATGATGGACTACATGTACAGGGGGGAAGTGAATATCTCCCAAGACCAATTGGCAGCGCTTCTTAAAGCCGCCGAATCTTTACAAATCAAAGGACTTTCGGAAAGTAAAGGTGGCGGCGGTGGGGGTGGAGGTAGTAGTggcggcggcggaggcggcAGCAACAGTTGtaacaacaaaaatgaacaaagaCAACAATTGttacaacagcagcaacaacaacaacagcaaaaAGTTCAATCGTCTTCTTCACAATCCATAGCACAGTCGTTAGACATTCCACATTCGTCTTCCTCCGGTCTTACTATCGAAAAGAACATTAAAGTTCCTAGGCAAAGTTTATCACAGACTTCGGTCGATCTACCTGAAGATTCTGCCAGCCCACAAATTTCCAGAGGACTATCCTCCagGGAAGGCTCGATAAGTCCGACGTCGttacggaaaagaaaaaaattgagaagaagaagtatcGGCGACGATAACTCGGTTGAAAATCACGAAGCATCTAATTCTAGCGATATTTCTCATTCTATGAGCATTCCTGCCCTTGGTATTGCCCCTGTTACTGATGAGAAGGTTCATTCCGATCCTACTGACTCACTCGGACGATCTGCTCTCATGCAACAACTCACTAAACCTGCGGACGAAATGCTTCagTTGCCAATCGAGAAACCAGAGCCTAATGACAACTTGATAGAGCCAAAGTCAGAGTACCTGGAGGACGCGGAAGAGAGTGTTGAAGATTTAACACTCGATGACGATATGAATGACCTCAATGAAATGGAACAAGATAATCCTAGAGCTGGACCATCCCACGACCCCAATCAACACCCTGGTCTCGCATCGTGGCATGTTACCGGTGATCGAAGTAACGCAGGGGGTGTCGTAGGGGCGGTTGGTGGCACCCCCGGCACTACAGACGAAGTCTTTCTAGCAGCCCAGGAGGCCGCCCAGGCCCATCGAGACTCACAAGaatcttggAGTGTATTTTTACCAGAGCCAACGTTTAATATTGCGGAACAATATTCAGCTCAAGAAAATAGCTTGGAAGCAACGTCAAAGCGACAATTTGCTTGCACCTTTTGTGGAAAACGATATACGGAAAAACGATACTTGCTCAATCACCAGGGAAGACATTGCTACAAAAATCCATCATCTTTGAGGAATAAATCCGTCCAAGTTAAACCCTTCCAATGTGGAACTTGCGGATCTGCATTCTCTCGACAACCAGACCTGATACAACATTGCAGACGTGATTGTGGACGTACGACAGAATGTTCTATTTGCGGAAGGACATTTTCTCAGAGATCTAGTTTTTATAAACATAAAAAGTTGCACTATTATCAGCAGCGTTTTCGTGGAGGGTTTGCAGATACCTATACTAACATGAATACTGAACTAGCAATGATAGCATCAAACCCATTCCAAACATCTTATCAACACTATCAGCAAAATGAATCGGACAAAACGCTCTTCGCCAgtcaaaataattttctttccgcTCTGAATGCTGTGAATTCATCAGCTTCGGCGACTAATCAACTTGCCAGTTCTTCGATTCAACCTGCTCAAGATAATCcacaaaagaaatttgtctGTCCGAAATGCGGTCGTGGATATAAATACATCGCAGATATGAGAAGACATTATCGTTTTCAATGTGGACAAAGTCCTAGATACAAATGTCCTTATTGTACAAAAAGATGCAAGAGCTCTTCCAATATGTATTCCCACGTTAGATTCATCCATAAAACTGAAAGGCAGTACATCATTGATTTATATACACGCTCTCTGAGGAAGAAAGACTTCAAAAATCCTGTGTGTGCCGCTTATGAAGAACCGTTTACTCAAATATTAGGAGCGCCAACCGTCCCAGTTCAGTACTACATATCTGATGTTAATGAACAATTCCATTGTCCGATGTGTAATGTAGGGTACTCTTCGAAGCTAGTCTTGGCTAGACATGTCAATTTACAGTGTGGCCAATTGCTCAGATTCCAGTGTCCGTATTGTGGTAGAAAGTCTAAACGAGCCTGGAACGTTGATGTGCACATTCGTACTAAACATCCTGGAAATGTAgtttttcatatcgatttATGTAATAAGAAGAAGTCCACAAATTTCAGAACGGAGATTCTTAAAAATTTTTTAAGACCCGTCTATTCCTTCGAGAAGCTCTACCTTCCGCAGGCAGGAGATACGAATATTTCTGCATCTGTAGCTCCGAGACGCACCTCAGAATTCCCTTGTCCAAATTGTACCAGCGCtttcaatagaaaaaataatttacaaaagCATTTAAGATTAGAGTGCGGACAGTTACCCAGATTTGGTTGTCCGTATTATTTCCCACCAGGCCATGATCTGGGAATGGGCGAAGATTGGAACTATGGAAATGATTATCACACGAGACATTATTGTCCTAAATGCGGGCGCAGTTATTCGCGTAAAGACCATATGAAAGAACATTATAAATATGAGTGCGGTAGACCGCCGAGATATCAATGTCCATATTGTCCCAGCCTCAAAACACCCACGTTCAGCATACTCTTGGTTCCGAGTATCAGAAGAAAGAAGGATGGTGAAGTATATGAAGATACCGAACAGCTAGCTGTTAGATTCCAATGTCCAACTTGCGACAGAAGTTATAATCGTCTTGACAATATGAAATATCATTGTAAACACGAGTGCGGAAAAGCTCCGAGATTTGAATGCCCATATTGTGGTAAACAGGGCACAAGATCATCCACAATATATCGACATATAAGAATAAAACATCCAAACCATGCTATCActttcTTCTCGGGATACGTGGAGTACAAAGCTAAGGTCGGAGCTAAAGTCGATAGACACAGATTCCCTTGTCCTAATTGCGGCAAAAGTTATACAACTAAAAGAAATAAACCGGGTGGTTTTCGCGTTCTTTTTATGAAGAATTCCAATAAGAAGAAGCGCACCTCCAAGAAAGATGTTCAGTTCAATTTAAACACTGGGAAATACCACTGTCCAATGTGCGGCAAAGGGTATGGAAGAAGGGATACTATGCTTGGTCATTATCGCTACGAATGTGGCCAAGCGCCACGGTTCCAGTGCCCTTATTGTAcattgaaaagtaaaaaagcgTCTAACGTTTATCAACACATTAGATGCCTACATCCGGATAAACCAGTGACTGCCTTGAAATTATATTAA
Protein Sequence: MEDDQQFCLRWNNHQSTLIQNFDTLLESGTLVDCTLAAEGKYLKAHKVVLSACSPYFEGLLSEHYDKHPVFILKDVKFKELKAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSESKGGGGGGGGSSGGGGGGSNSCNNKNEQRQQLLQQQQQQQQQKVQSSSSQSIAQSLDIPHSSSSGLTIEKNIKVPRQSLSQTSVDLPEDSASPQISRGLSSREGSISPTSLRKRKKLRRRSIGDDNSVENHEASNSSDISHSMSIPALGIAPVTDEKVHSDPTDSLGRSALMQQLTKPADEMLQLPIEKPEPNDNLIEPKSEYLEDAEESVEDLTLDDDMNDLNEMEQDNPRAGPSHDPNQHPGLASWHVTGDRSNAGGVVGAVGGTPGTTDEVFLAAQEAAQAHRDSQESWSVFLPEPTFNIAEQYSAQENSLEATSKRQFACTFCGKRYTEKRYLLNHQGRHCYKNPSSLRNKSVQVKPFQCGTCGSAFSRQPDLIQHCRRDCGRTTECSICGRTFSQRSSFYKHKKLHYYQQRFRGGFADTYTNMNTELAMIASNPFQTSYQHYQQNESDKTLFASQNNFLSALNAVNSSASATNQLASSSIQPAQDNPQKKFVCPKCGRGYKYIADMRRHYRFQCGQSPRYKCPYCTKRCKSSSNMYSHVRFIHKTERQYIIDLYTRSLRKKDFKNPVCAAYEEPFTQILGAPTVPVQYYISDVNEQFHCPMCNVGYSSKLVLARHVNLQCGQLLRFQCPYCGRKSKRAWNVDVHIRTKHPGNVVFHIDLCNKKKSTNFRTEILKNFLRPVYSFEKLYLPQAGDTNISASVAPRRTSEFPCPNCTSAFNRKNNLQKHLRLECGQLPRFGCPYYFPPGHDLGMGEDWNYGNDYHTRHYCPKCGRSYSRKDHMKEHYKYECGRPPRYQCPYCPSLKTPTFSILLVPSIRRKKDGEVYEDTEQLAVRFQCPTCDRSYNRLDNMKYHCKHECGKAPRFECPYCGKQGTRSSTIYRHIRIKHPNHAITFFSGYVEYKAKVGAKVDRHRFPCPNCGKSYTTKRNKPGGFRVLFMKNSNKKKRTSKKDVQFNLNTGKYHCPMCGKGYGRRDTMLGHYRYECGQAPRFQCPYCTLKSKKASNVYQHIRCLHPDKPVTALKLY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01200306;
90% Identity: iTF_01200306;
80% Identity: iTF_01200306;