Basic Information

Insect: Phosphuga atrata
Gene Symbol: zfh1
Assembly: GCA_944567605.1
Location: CALYMX010000056.1:10188-21055[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0047 1.5 12.2 2.3 2 23 53 75 52 75 0.97

2 8 0.0015 0.49 13.8 0.3 3 23 106 126 104 126 0.95

3 8 1.2e-05 0.0038 20.4 0.6 2 23 133 154 132 154 0.97

4 8 2.2e-06 0.00071 22.7 5.9 1 23 163 185 163 185 0.99

5 8 9.5e-05 0.03 17.6 1.0 1 21 191 211 191 212 0.95

6 8 8.7e-06 0.0028 20.8 1.4 1 23 805 827 805 827 0.95

7 8 0.00023 0.072 16.4 9.4 1 23 833 855 833 855 0.98

8 8 0.069 22 8.6 7.0 1 21 861 881 861 882 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0047	1.5	12.2	2.3	2	23	53	75	52	75	0.97
2	8	0.0015	0.49	13.8	0.3	3	23	106	126	104	126	0.95
3	8	1.2e-05	0.0038	20.4	0.6	2	23	133	154	132	154	0.97
4	8	2.2e-06	0.00071	22.7	5.9	1	23	163	185	163	185	0.99
5	8	9.5e-05	0.03	17.6	1.0	1	21	191	211	191	212	0.95
6	8	8.7e-06	0.0028	20.8	1.4	1	23	805	827	805	827	0.95
7	8	0.00023	0.072	16.4	9.4	1	23	833	855	833	855	0.98
8	8	0.069	22	8.6	7.0	1	21	861	881	861	882	0.96

Sequence Information

Coding Sequence: ATGGTGGCGCGAAGTGAGAGCATGTTTGGGTGCTACGACAGCTACTCTTATAGACTTTGGAGTCTCGCCAATGTGTGGAACACCTGTCAATTTCCAACCAATGGGGTGGTGAAGAAAGAAGGGGACGAGACCAGTTCCGGCTCTGAATATTTCATCAAGTGTCCGCAATGCCAGAAGGGTTGTCAAACCTTTCAATCTTTGAAAGAGCACATGGAAACGTCACATCCGGATCTGTGCTCTGAGAACGGTATCGTACCGACTCCGAGCGCCGTTTCTCCGACGCCCAGCTTGGTCGGACCCGGTGGTCCGTTCGGATGTTCGCAGTGCACGGCGTCGTTCGCCAGCAAAGACCAATTGGAGAAACACGAATTGCTTCATTCGCCTAACGCTCAAGTGTCCTGCAAGATTTGCAACAAGACTTTCGCCAACGTGTACCGTTTACAAAGACACATGATCAGCCACGACGAGAGTGCCGTCCTCCGCAAGTTCAAATGCACAGAATGCGATAAAGCATTTAAATTCAAACACCACTTAAAAGAACACATTAGGATACACAGCGGCGAAAAACCGTTTGAATGTGGAAATTGCGGCAAGAGATTCTCCCACTCTGGTTCCTACTCGAGCCATATGACATCGAAAAAATGTTTAGTGATGAATTTGAAATTAGGAAGGACACGGGCGCCAAATGCAAATGCGCTGCTCGAGAAAAATGCTTCCCAAAACGTAAGAGGACAAAAACGCCCTCCGACGAATCCCTTAAATAATAATATAACCACCACCAACCACAACGCATATTTACAACCAATGCTACCTAAATATACAGAAGCTGCCGCTGTATTCCTTCAAAACTCTTTAGCTTCGAATCCTGCCATGCATCCTTTCTATATGACACCCGGTATGCTCAATGCTAATGGCCATGCCCTTAATCCCTACATGCCTTCTATAGGACACCTCCTAGAACAGCTGCAAAATGCTTCTCCCCACAAACAAATTCTCGACCAACCCGAAACTCAAATAGAAGAAATTAAATCAGAATCCCCGAAACCGGATAACCTAAACAAATCCAATTCCTCAAGCTGTGGTGATTTAGTAATGGACGAAGAAGCCGATGCAAAATCCGAAACTACCGAGAAGACCTCAGAAGCCACCAGTAATGGAGATCTCGAAGCGGTCAAACGGATTTTAGATACTGTAAACGCAAGTGTCACCAAACAGTTCCTTCAAGCCAACATGCAAAAGTTTTCCGATAATTCTAGCGATTGCCAAAGCATAAGATCAACACATTCCCCTTCAGAATTATATTGCACTAATTGCAAAAAATGTTTTCTCAACCAGACAGAGTTGGATGAACATGATTGCGATCATTGCGATATGAAAAGCGAAGGATTAGCCGCTAAACTTGAGGACGCTATAACTCCGAAAACTGAAAACGAGATTGGAGGTGTTAGCGGAAACGAAGAAGATGACGATAAACATCACGACAGAAATGAAGATTATGAAATGGATAGTGAATCTGTTACAACTACCGACCAATTAACGGAAGACGGAAGGAAAGTTAGGGTCCGTTCCCTAATTTCTGACGAACAGTTGAAGGTGTTGAAGGATAATTATGCTTCTAATCCGCGCCCAAAGAGGGAAGAATTATCTAAAATAGCCGACCAAATCGGATTTCCAGTGAGAGTTGTCCAAGTATGGTTTCAGAACACTCGTGCTCGTGACCGAAGAGAAGGTAGACTCATCCAAATTCCATACAATACGCCGCCGATGCTTCCTAGGTTTCAATCCGTGGTGCCTTCAAACCCACAATATATCGGACACAAAGTATATCCTTTAGTGCAATCCCCAAACCACTACACATCCGAACAACCTTTAGATCTTTCCACCAAAAAAGATACCTCCCGAGAATCTTCGCCAGCCAGTTCCCCTCATCGGCCTTCCTCCATAAATCATCACTCCGACTCCGGAGAAGAAGTAGTAAACTTGAGCCATAAATCTTCTAGAAGCCCAACTCCGTTTCAACATTTACCTTACCAAAGTCATTACCAAGCGTCTAATTGTTCGTCCGAACCGAGGCGATCGCCCTCCCCAGTAGATTTTAACAACAGCAGTCGGCTAGCGCACATCTTAGCCCAGCCCGCTCACAAACTCGCTCTCTCGACTATGGGACTGGTACCCATGGAGAGACTGATACAGTTCGGACCTCCAGATATTCCAAGCTTGACTCAGTTGATAAACAATAGGATTTCTAGCATAAGTCCGAATTCAGATAAGAGATCGTGGACTATGGACAACGGAGATCTAATGGACCAAGACGATGACAGTCATGGAAAACGAAGCAAAGTTTCCCAATTGGTTATGAAGAGTTTGGGAAGTCCCATGTTAGGAAATCAAGAAGTTGAAATTGAAGGACAGTTCACTTGTGATCAATGTGATAAAGCTTTTTCGAAACAAAGCTCCTTAGCCAGACATAAATACGAACACTCGGGGCAACGTCCGCATAAATGTGATGAGTGTCCGAAGGCGTTCAAGCATAAGCATCATCTTACGGAGCACAAGCGGCTTCATAGTGGAGAAAAGCCGTTTCAGTGCTGCAAGTGCTTGAAAAGGTTCTCGCATTCGGGTTCGTACAGCCAACATATGAATCATCGTTATTCCTACTGTAAGCCGTACAGAGAGTAA
Protein Sequence: MVARSESMFGCYDSYSYRLWSLANVWNTCQFPTNGVVKKEGDETSSGSEYFIKCPQCQKGCQTFQSLKEHMETSHPDLCSENGIVPTPSAVSPTPSLVGPGGPFGCSQCTASFASKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAPNANALLEKNASQNVRGQKRPPTNPLNNNITTTNHNAYLQPMLPKYTEAAAVFLQNSLASNPAMHPFYMTPGMLNANGHALNPYMPSIGHLLEQLQNASPHKQILDQPETQIEEIKSESPKPDNLNKSNSSSCGDLVMDEEADAKSETTEKTSEATSNGDLEAVKRILDTVNASVTKQFLQANMQKFSDNSSDCQSIRSTHSPSELYCTNCKKCFLNQTELDEHDCDHCDMKSEGLAAKLEDAITPKTENEIGGVSGNEEDDDKHHDRNEDYEMDSESVTTTDQLTEDGRKVRVRSLISDEQLKVLKDNYASNPRPKREELSKIADQIGFPVRVVQVWFQNTRARDRREGRLIQIPYNTPPMLPRFQSVVPSNPQYIGHKVYPLVQSPNHYTSEQPLDLSTKKDTSRESSPASSPHRPSSINHHSDSGEEVVNLSHKSSRSPTPFQHLPYQSHYQASNCSSEPRRSPSPVDFNNSSRLAHILAQPAHKLALSTMGLVPMERLIQFGPPDIPSLTQLINNRISSISPNSDKRSWTMDNGDLMDQDDDSHGKRSKVSQLVMKSLGSPMLGNQEVEIEGQFTCDQCDKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00429770;
90% Identity: iTF_01196579;
80% Identity: iTF_01196579;