Patr107162.1
Basic Information
- Insect
- Phosphuga atrata
- Gene Symbol
- topi
- Assembly
- GCA_944567605.1
- Location
- CALYMX010003023.1:103723-111108[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.001 0.32 14.4 2.4 2 21 107 126 106 127 0.94 2 14 1.2e-06 0.00037 23.6 0.7 1 23 152 174 152 174 0.97 3 14 0.064 20 8.7 2.2 3 23 182 202 181 202 0.95 4 14 0.65 2.1e+02 5.5 0.1 2 17 221 236 220 240 0.81 5 14 2.1e-06 0.00067 22.8 1.6 2 23 275 296 274 296 0.97 6 14 0.55 1.8e+02 5.7 0.1 1 18 302 319 302 323 0.78 7 14 0.25 81 6.8 3.7 2 22 339 359 338 362 0.87 8 14 6.5 2.1e+03 2.4 0.4 1 23 620 643 620 643 0.80 9 14 0.0048 1.5 12.2 0.4 1 23 647 669 647 669 0.97 10 14 2e-05 0.0063 19.7 5.4 1 23 675 697 675 697 0.98 11 14 0.04 13 9.3 0.2 1 23 703 728 703 728 0.96 12 14 0.2 63 7.1 2.9 1 23 734 756 734 756 0.86 13 14 2.5e-06 0.0008 22.5 0.5 1 23 762 784 762 784 0.98 14 14 1.7e-05 0.0055 19.9 1.9 1 23 790 813 790 813 0.98
Sequence Information
- Coding Sequence
- ATGAATAAAAGTGAGCAGATCACCCATCTAAAGCTGCACAGGATCCACCCGGATGGGACGATCCACTCAGTCCAACTCAGCTTCGACCCGAAAACCCAAAAACTTCTAGGTAAGACCCACATAACCCCAACCGTGCCGCCGCCTGCGCCCATCAACCCACAAACCACCTTCAACTTCAACTACACCTTAAACCTGAATTCCTCGATCCGAGTGGTGAAATTGGGTGGGATCGAGGACCTGAACCCACTGAACTTCCCGCAAGATATACCAAATGAGGAGAAAACCTCGCGCAAGGTGCCCAACATTCCCAGCATGATCCGCTGCCAGAACTGCGACACGAACTTCCCCACCAAATACCAATTTCAGCGCCACCAGTGCGAGTTCAACGCCGAGAAAGTCGTCCTCAAGCCGAACATCGACGTCAAGGACGTCGAGAAAGGGGTCCGGATGAAATTCGATTGCCCCACGTGCGGGAAACAATTTGTAAGCAAGAACAATCTAGAACGGCATCTGACCAGCCACGACGAAGACAACGTGAACATCTGCGAGTTTTGCAATAAACACTTTGTCAGCGAAAACCGGTTGCGGATTCACAAGGAGAACCATTGCAAAAAGGCCGGGGATATCTCCAAGTTTTACCGTAGCGACGTCACCGTTTGGAAGTGCGTCAAATGCAACCAGGTCTTTTCCACAGACAGTTTTGCCAATCTCCATGCGGATCTTTGCACGGAAATCTTGGACCAAGACGACTTCCAAACCAAAACCGACGAGGATTTCGAAGGCAGCAAATACGTGGAGAAAGTCCTTACGGAACTGCTGTTGCAATGCGAGTATTGCAATAAGACTTACTCAGATAAAAAATCTCTGCTGATTCACCAGAAAACCCATTCCACTGAAGTCAATTACAAATGTGTCGTTTGCAACGAGGTTTTTGACTCGTATATAACAGCTGGGAAACACTGGTTGACGCAGTGTTCGAACGAAGCCAATCTCTTCTATTTGCCGAAGCTAACCTATTGCCAGTTCTGCGACAGGACGTTTAAATCGCACGAGGTTCTCTACTCCCACAAGATCAAGAAGAAACATTACACGCCAAAGAAGTTCTCCACTAAAAAACCTTCCTCGCCAAAAGTCTCTTCTTCATCTCCAACCACCAATTTCTTATCTTCAACTCAAACGACTTTCTTAGCCTCAACCTCAACAACTGAGGTCTTGTCCACTTCGTCCCCAACCCGGATGTATTTATCTTCGTTGTCTCCAACAACACAGTTTTTGTCATCTTGTTCAACCCCGGCAAATTTCTTGTCTTCAACCCCATCAACAACTAACTATTTGGCATCTTCATCTCCAACAACATATTTCTCATCTGCAACGAATCCAACGGCGAATTTCTTGTCTTCGTCGTCTCCAACAACAAATTTCTTAACTTCAATACCCAAAGCCATGTCTTCTTCCCCGACGAAAAGTTTCTGTTCCTCTCCCACCAGGATCACATCTTCGTGTTCCCCGAGCAAAACATCGCAACTTCAAATCGCGCTCTCTTCCCCAAACAAGATGGTGTCTTCTTCATCCCCAAAAGAAACGCCTCCAAGCGAAGTCCTCTCCCATTCATCAGAATTTTTCTCCTCTTCGAAGCTCTCACCTTCGTCCAAAACCGAGGACAAGGAGACTATAATTAAACTGATTGAAGACGTGCTTTGTTCGATCAACGTCGCGGACGAGGTCGCGGTGAAGAGCGAGGTGGTGAGCGAGTGCGGGAGCGTCGAAGAGGTGAAGAAGCGGCGCGGGCGAAAGCGCAAGCACTCGCCGGGGAAGGCGGTGAAGCGCGTCGGAGGAGTCGTCGAGGCGGGGTTCAAGTATCAGTGCGAGAGGTGCGTCGAGGTCTTCGACTGCGTCGGCGAGCTAGAAGGTCACCGAGATCGCGAGCATCCCGCCAACTACAAATGCGAGGAGTGCGACCAGGTGGTTCACAGTTCGAAAGCCTTGTTGATCCACAGCAGAGCGCACCAGAGTCTGAAGCCGTACGTGTGCGAGATCTGCAAACGCTGTTATTCCCAAACCTCGCACTTGTGGCAGCACATGCGTTTCCACCAAGGTATCAAGCCGTTCGCGTGTCCGCACGAGGGCTGCGAGGCGCGGTACACCATCCGGCCGGATCTGAAGGACCACATCAGGAAGGTGCACACCAGAGAGCGGCCCTTCAAGTGCTCCGTGTGCGACAAGTGCTTCCTGACCGGATCCGTTTACTACCAGCACCGGCTGATCCACACCAACGACCGCAGATACGCCTGCGACATTTGTAACAAGAGATTCTTCCGGGCGGATGCGTTGAACAATCACCGGCGGATCCACACGGATGAACGGCCTTATCCTTGTGACGTGTGCGGCCGTCATTTTAGACAGAAAGGCGACCGGAACAAGCACGTCAGGACGCAGCATCCGGAATATCACACTTAA
- Protein Sequence
- MNKSEQITHLKLHRIHPDGTIHSVQLSFDPKTQKLLGKTHITPTVPPPAPINPQTTFNFNYTLNLNSSIRVVKLGGIEDLNPLNFPQDIPNEEKTSRKVPNIPSMIRCQNCDTNFPTKYQFQRHQCEFNAEKVVLKPNIDVKDVEKGVRMKFDCPTCGKQFVSKNNLERHLTSHDEDNVNICEFCNKHFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCVKCNQVFSTDSFANLHADLCTEILDQDDFQTKTDEDFEGSKYVEKVLTELLLQCEYCNKTYSDKKSLLIHQKTHSTEVNYKCVVCNEVFDSYITAGKHWLTQCSNEANLFYLPKLTYCQFCDRTFKSHEVLYSHKIKKKHYTPKKFSTKKPSSPKVSSSSPTTNFLSSTQTTFLASTSTTEVLSTSSPTRMYLSSLSPTTQFLSSCSTPANFLSSTPSTTNYLASSSPTTYFSSATNPTANFLSSSSPTTNFLTSIPKAMSSSPTKSFCSSPTRITSSCSPSKTSQLQIALSSPNKMVSSSSPKETPPSEVLSHSSEFFSSSKLSPSSKTEDKETIIKLIEDVLCSINVADEVAVKSEVVSECGSVEEVKKRRGRKRKHSPGKAVKRVGGVVEAGFKYQCERCVEVFDCVGELEGHRDREHPANYKCEECDQVVHSSKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICNKRFFRADALNNHRRIHTDERPYPCDVCGRHFRQKGDRNKHVRTQHPEYHT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -