Poka011816.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phortica okadai
Gene Symbol
dsf
Assembly
GCA_034638295.1
Location
CM067850.1:41908267-41928976[-]

Transcription Factor Domain

TF Family
RXR-like
Domain
zf-C4|RXR-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers. Each zinc finger contains a group of four Cys residues which co-ordinates a single zinc atom. RXR functions as a DNA binding partner by forming heterodimers with other nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR. All RXR heterodimers preferentially bind response elements composed of direct repeats of two AGGTCA sites with a 1-5 bp spacer. RXRs can play different roles in these heterodimers. RXR acts either as a structural component of the heterodimer complex, required for DNA binding but not acting as a receptor, or as both a structural and a functional component of the heterodimer, allowing 9-cis RA to signal through the corresponding heterodimer. In addition, RXR can also form homodimers, functioning as a receptor for 9-cis RA, independently of other nuclear receptors. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, RXR has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [cite:PUB00121610], [cite:PUB00121611], [cite:PUB00121612], [cite:PUB00025660], [cite:PUB00121613], [cite:PUB00092048], [cite:PUB00092725], [cite:PUB00092726], [cite:PUB00016724], [cite:PUB00059514PMID:18971932
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.5 5e+03 -2.6 0.0 159 190 48 98 28 101 0.71
2 2 6.7e-56 2.2e-52 178.2 2.5 2 199 714 903 713 905 0.92

Sequence Information

Coding Sequence
ATGAcgcagATTTCATTTGGCGAAGTGGTACTGGAGGATATTCGTTGTAATGGGCTGAATAAGGAAGTCTTGAAAGTGGTACAGTGTCGTATGAAATATGAGCACGGCAGTCGTGGCAAAAAGGAGGGCTTTGCAAATATTCAGCTTTTGCAAACAATGTCCAATGTAACGCTCAAAATCAAGTTCATGAAGAAATCAAACAACGACTATAACATCTATTTTACCAAGGAGATTTTCATAGATGGCTTGACCGACTTTGAGGGTATCGGGCAGACACCGCCGGGACAGTCATTGGCAACGTTCGATGCCGCCGAGCGTGTATCGGTCAACGAGCCATATGGACCTGTGCTTGAGATCTTTGCTGGCGATCGCCTGCTGGACATACCCTGCAAAGTATGCGGCGATCGTAGCTCAGGCAAGCATTATGGCATCTACAGCTGTGATGGTTGTTCGGGTTTCTTTAAGCGCAGCATACACCGCAATCGCATTTACACCTGCAAAGCAACTGGCGATCTCAAAGGGCGCTGCCCCGTGGATAAGACGCATCGTAATCAATGTCGTGCCTGTCGTTTGGCCAAGTGCTTTCAATCGGCCATGAACAAAGATGCTGTTCAACATGAGCGCGGCCCACGCAAACCCAAATTGCATCCACAActacatcatcatcaccatcacgcACACCAtgcgcatcatcatcatcatgcacACCacgccgcacacacacacgctgcACACGCCCATGcggccgccgccgctgctgcagcCGTAAATGGCTTGACGCCACACCATGCCGCACATCATCATGCCGCCGCTGCAGCACATCATCATGCCGCACACTTGCCCGTCTCGCTGGTGACAAATGTTTCGGCCTCGTTTAACTACACATCGCACATTTCGACAACACATCCGAGCGGCTTTCATGCGCCGCATCATCACCCGggcagcggcagtggcggCCACCCGCATCCGACCGCATTCCATCATCCGGGGCATGCGCTAGCGCCGCATAGCAATGGCGTGAGTTTACAAAATGGCGGCACCGTTGTCAGCCAACCGACGACATTGCCCTTTCCGCCACATTTACTGCCACAAATGCATCACAATCTTATTGCGGAGGCGGCCAGCAAGTTGCCCGGCATCACAGCCGTCGCCGCAGCTGCCGCCGCAGCCACAACACTTGGCGGCAGCGGTTTGCCGCCGCAGGCACAGCAACGTGCAACTTATGACTTGACTACAACGTCGGTGACGGCAGCCAATTCAAATTCCGCCGGTTCTGGCTCGGCTGCGGGTAGCGCGAATAGCGCGGAGTTCTATGCAAAGTCTACATCGTCGCTAACGCAACACAATTACTCATCGCCATCGCCAACGAATTCAATACAATCGATATCGAGCATCGGCGGCCGTTCGTCGCTGGGCAGTGAGAGCTCACGGGTCAATGTCGAGACGGAAACGCCATCGGCAACGCCACCGTTGTCGGCTTCTGCATCGCCAGCGCCGTCTTTAACGGATACAATGAGCATTGCCGCCTCGTCAGcgtcgccgccgccgccatcaacagcagcacatCATGCACATCATCAGGGCAGCACAATAGTTACAACGGCGCAGACACAACATGAGGGACAACATTTGCACACGGCTTCCAGCATGCTGCTGCAGAGCAtgcaacacagcaacaacaatcatacTATCAAACaacactacaacaacaataacaacaactatatgCAATCACGTTCACAAAATTCAACGCCCACGCCCACAACGCCTACGCCAAATGAGCACCTACTACACAACAatcacaacgacaacaacaacaacaatcaaacacCACCGCCGCCTCCACCCTCAACATCTTCAGCATCACTTAACATGAATAGCtcaacaccatcatcatcatcttcttcCGCATCGGCCACAGCCACAGCCACCATAACAGCCAGCGCCGTTTCCGCTTCCGCTTCGGCTGCGGCCTTGTATGCTGCACGACAAAATGGTTTCCTTGAGCTGCTACTAAGCCCCGACAAATGTCAGGAAATCATACAGTATCAAGTGCAGCACAACACTCTGCTCTtcccgccgccgctgccacaGCAATTGATTGGCATGGATTCGCGTCTGCTGTCCTGGGAAATGCTGCAAGAGACCACCGCACGTTTGCTCTTCATGGCGGTGCGTTGGGTCAAGTGTCTGATGCCATTTCAAACgctatcgaagaatgatcaaCATTTGCTGCTGCAGGAATCATGGAAAGAACTTTTCCTACTCAATCTGGCACAATGGACAATCCCGCTCGATTTGACGCCCATACTTGAATCGCCGCTAATCAAAGAACGCGTGCTGCAGGACGAGGCCACGCAAaccgaaatgaaaacaatacaAGAGATACTCTGCCGTTTTCGACAAATTACGCCCGATGGCAGCGAAGTCGGTTGCATGAAAGCAATTGCGCTCTTTGCGCCCGAAACTGCCGGCTTGTGCGACGTGCAACCCGTTGAAATGTTGCAAGATCAAGCCCAATGCATACTCTCGGATCATGTACGTCTTCGTTATCCGCGTCAGGCCACACGCTTCGGGcgtctgctgttgctgttgccctCACTGCGTACAATACGCGCGGCGACAATTGAAGCGCTCTTTTTTAAGGAGACAATTGGCAATGTGCCGATTGCGCGTTTATTGCGTGACATGTACACAATGGAACCGGCGCAGGTCGAGAAGTAG
Protein Sequence
MTQISFGEVVLEDIRCNGLNKEVLKVVQCRMKYEHGSRGKKEGFANIQLLQTMSNVTLKIKFMKKSNNDYNIYFTKEIFIDGLTDFEGIGQTPPGQSLATFDAAERVSVNEPYGPVLEIFAGDRLLDIPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKCFQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAHHAHHHHHAHHAAHTHAAHAHAAAAAAAAVNGLTPHHAAHHHAAAAAHHHAAHLPVSLVTNVSASFNYTSHISTTHPSGFHAPHHHPGSGSGGHPHPTAFHHPGHALAPHSNGVSLQNGGTVVSQPTTLPFPPHLLPQMHHNLIAEAASKLPGITAVAAAAAAATTLGGSGLPPQAQQRATYDLTTTSVTAANSNSAGSGSAAGSANSAEFYAKSTSSLTQHNYSSPSPTNSIQSISSIGGRSSLGSESSRVNVETETPSATPPLSASASPAPSLTDTMSIAASSASPPPPSTAAHHAHHQGSTIVTTAQTQHEGQHLHTASSMLLQSMQHSNNNHTIKQHYNNNNNNYMQSRSQNSTPTPTTPTPNEHLLHNNHNDNNNNNQTPPPPPPSTSSASLNMNSSTPSSSSSSASATATATITASAVSASASAAALYAARQNGFLELLLSPDKCQEIIQYQVQHNTLLFPPPLPQQLIGMDSRLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKNDQHLLLQESWKELFLLNLAQWTIPLDLTPILESPLIKERVLQDEATQTEMKTIQEILCRFRQITPDGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRYPRQATRFGRLLLLLPSLRTIRAATIEALFFKETIGNVPIARLLRDMYTMEPAQVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01195328;
90% Identity
iTF_01195328;
80% Identity
iTF_01195328;