Poka003979.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phortica okadai
Gene Symbol
sd
Assembly
GCA_034638295.1
Location
CM067848.1:48965558-49000129[-]

Transcription Factor Domain

TF Family
TEA
Domain
TEA domain
PFAM
PF01285
TF Group
Helix-turn-helix
Description
The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and AbaA. The TEA domain is located toward the N terminus of eukaryotic transcription factors of the TEA/ATTS family. It shows a three-helix bundle with a homeodomain fold [3, 1]. Two α-helices are nearly anti-parallel and pack on either side of the third one, which is the DNA-recognition helix of the TEA domain. Phosphorylation of one or both of the two conserved serines found on the DNA-binding surface could interfere with DNA-binding activity, by introducing electrostatic repulsion and/or steric hindrance, and help regulate the transcription factor activity of the proteins [2, 1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 7.5e-31 8.7e-27 93.6 0.1 2 66 124 190 123 192 0.96
2 2 2 2.3e+04 -6.1 2.7 42 57 415 430 396 436 0.62

Sequence Information

Coding Sequence
ATGTTATTCAAAACTGACAATAAATGCATTGAGCATGATgatcataatgatgatgatgatgataatgttaatgatcataatgatgatgatgatgatttaaCATCcgtcaacatttttttaaaaagtgaAGAACATAACGGCACCAACGTGGCGCCGTTAACTAAAAACTTGGATTACCTGGAGGAATTCAGGGCCTTGTCCGacGGCATCGTCGGACCCGGCACCATATCCTCGCCGTGGACGCCCGTTGGCGCTGGTCCGCCAGGCCCGCTGGGACCCTCCGACACAAATGGCAGCATGGTGGACAGCAAAAATTTGGATGTCGGCGATATGAGCGATGACGAAAAGGATCTGTCGTCAGCCGATGCCGAGGGAGTTTGGAGTCCCGATATCGAGCAAAGTTTTCAGGAAGCGCTCTCAATATATCCGCCATGTGGTCGTCGGAAAATTATACTCTCCGATGAAGGAAAAATGTATGGACGCAATGAGCTCATCGCACGTTACATCAAATTGCGCACCGGCAAAACGAGAACGCGCAAGCAAGTCAGCTCGCACATTCAAGTACTGGCAAGACGAAAACTACGCGAAATACAGGCCAAAATCAAAGTTGAACCAAATGGCCTCAGTCCAAATGGTCTGTCGATGCTGCTCAATGAGAAAGAGAAAGCCTTACAGGCGATGAGCACAATGACCAGCTCGCAGATCGTTTCCGTCCAGGCGGCCAAGAATCTCGCAATGACAGCCATGCGCCATCACCACCACCACGCCCACCATGCTCACCACGCCCACCATGCGCACGCTCATGCACATGCACACTCACATGGAGCGCGTCCGTTGCATCATCCGTTGCATCATCAGCACATTGGTAGCATGACGATGGGCATTGGTGGTCTCACATCGCCGccgttaacaacaacaacagcagcagcaacaacaccgcTGACACTATCactgccaccgccgccgcatCCCTTGGCAACCGCAATTGGTGATGGCAGTGGAGGGCAATCGTCGTCAGCTGCAGCCGTAACagcaccaccgccgccgccgccaccacatCCATTGGCGGCACACACGCATTTGGAACCACCACCGCCGCATCAGCCGACGCATCATCATCACTTTGGCGGCGCCGGcggtcatcatcatcagcagcagcagcatcatcaacaccaccaccaccaccatcatcatcatattggtcatcatcaccaacaacagcaacaggcggctgttgttactgctgcttacttgcaacaacatcaacaacaccaacagcaacaacaacagcaacaacaacagcaacaacaagaacaacaacaattgcaatgcCTATCATCGGGCTCATCAGCGTCGGCATCATCGTCGGTCTCATCGATCATTGATGCTGTTAACGGCGGACCCGGTGGTGGTGTTGGCGCTGCTGGCGGTGCAGCCAGTGTTGGTGGCAGTGGCGGTGGCGCTTTATTGACGACCGCGCGTGCCCTTCATCATCCGCCGTTGTATCCGGGCCAATTTTGGCAGCCAGGCCTGCAGCCGAGCACCTCACAAGATTTTTACGATTACAGCATCAAGCCATTCGCACAGTCCACATATCCCGCCGGCAAGCCATCGACCGCTGTCTCTGGTGACATCGAAGCGTGTCTACCGTCAACGCAGCTGCCGTGGGAGGGACGAGCCATTGCGACGCACAAATTCCGTTTGCTCGAGTTTACCGCTTTCATGGAAATCCAAAGAGGTGATATTAATCACAGTCACTTGTTTGTACAACTGGGCGGCAAACCATCCTTCTCCGATCCACTACTTGAGACTGTTGATATACGACAAATCTCCGATAAATTCCCAGAAAAATCGGGTGGTCTTAAAGATCTCTATGAGAAAGGTCCACAGAATGCATTCTATTTGGTAAAATGCTGGGCGGATCTCAATACCGACATCACAACGGAGGGCGAATTCTATGGCGTAACGAGCCAaTATGAGAGCAATGAGAATGTTGTGCTCGTCTGTTCAACGAAAGTTTGCTCATTTGGCAAACAGGTCGTCGAGAAGGTCGAGACTGAGTACTCGCGTTTGGATAACAACCGTTATGTTTATCGCATACATCGCTCGCCCATGTGCGAGTACATGATCAATTTTATACAGAAGCTGAAGAACCTACCTGAACGTTATATGATGAACAGCGTGCTTGAGAACTTTACAATACTGCAAGTAATGCAAACGCGTGACACGCAAGAAACGCTGCTCTGTATAGCGTACGTCTTTGAAGTGGCGGCACATGGCAGTGGCGCCACACATCATATATACCGTTTGATAAAGGAATAG
Protein Sequence
MLFKTDNKCIEHDDHNDDDDDNVNDHNDDDDDLTSVNIFLKSEEHNGTNVAPLTKNLDYLEEFRALSDGIVGPGTISSPWTPVGAGPPGPLGPSDTNGSMVDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVEPNGLSPNGLSMLLNEKEKALQAMSTMTSSQIVSVQAAKNLAMTAMRHHHHHAHHAHHAHHAHAHAHAHSHGARPLHHPLHHQHIGSMTMGIGGLTSPPLTTTTAAATTPLTLSLPPPPHPLATAIGDGSGGQSSSAAAVTAPPPPPPPHPLAAHTHLEPPPPHQPTHHHHFGGAGGHHHQQQQHHQHHHHHHHHHIGHHHQQQQQAAVVTAAYLQQHQQHQQQQQQQQQQQQQEQQQLQCLSSGSSASASSSVSSIIDAVNGGPGGGVGAAGGAASVGGSGGGALLTTARALHHPPLYPGQFWQPGLQPSTSQDFYDYSIKPFAQSTYPAGKPSTAVSGDIEACLPSTQLPWEGRAIATHKFRLLEFTAFMEIQRGDINHSHLFVQLGGKPSFSDPLLETVDIRQISDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDITTEGEFYGVTSQYESNENVVLVCSTKVCSFGKQVVEKVETEYSRLDNNRYVYRIHRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMQTRDTQETLLCIAYVFEVAAHGSGATHHIYRLIKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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