Preg000070.1
Basic Information
- Insect
- Phormia regina
- Gene Symbol
- -
- Assembly
- GCA_001735585.1
- Location
- MINJ01167829.1:3318-7892[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0032 0.34 12.5 0.5 3 23 93 114 91 114 0.95 2 8 0.0037 0.39 12.3 1.0 3 23 306 327 305 327 0.95 3 8 0.013 1.4 10.5 0.1 3 23 584 605 583 605 0.95 4 8 0.016 1.7 10.3 0.1 2 23 655 677 654 677 0.91 5 8 0.012 1.3 10.6 3.6 2 23 718 740 717 740 0.96 6 8 0.12 12 7.5 4.2 2 23 754 776 753 776 0.92 7 8 0.00033 0.034 15.6 0.3 3 23 839 860 838 860 0.95 8 8 0.017 1.8 10.2 0.8 1 23 950 972 950 972 0.99
Sequence Information
- Coding Sequence
- ATGGCCGCTTCTATATATGCAACCCCACCGCCTGATTTAAaagataatgatgataatgagGAACATAAtaatacaacagcaacaacaatggCTGCTGTAGCAGCAGCTGCTAATGCAGCCATGCAACTACAATTATTAGAAGCCATAAATGATGCTGCCAAAAAAAGACGCAAACAACACAATCCCAGTCGCATGGATGAGGATACAAAaTATAACTCCGATATGGaggaacaacagcaacagcaacaggcTTATAATAATCCATATCATACCTTCTGTAAGGAGTgtggtgaaaattttgaaaatgaatttaaattaagtcTACATATGTTGCAAGAACATAATGATAATGCCGAAGGATTTAGCAACAATCAATCTACTGCAGGCGACTTGACACCCTTAGATATTTTGGCCTCGGTAAAGGTGAAATTGGAAAGACCTGAATGTGAGTCACCCTCTTCGAATCATAATTTGGAACAGGTTACTAATAGTTCTCAAGAGCAGCAACATAATAGTTCTTCTGCTACTAGTAATATGCTAACAAATGGTAAAGATCAACCACAGTTAACACAACCCTGGATGGGAGCACCTACTATGCCACCCATGGGTTTTCCATTTCCTCCCGAGGCAGCTGCTGCAGCCGCTTTACAAGCAGGCGGCTATTTACCTTTACTGGGGGTACCTGGTTTTCCAGGTGTTGATGGCATTAATCGTCCTCCTCTTAGAATTTTTAATCCTGAAGCTTTTTCCCAACAAAAGTTACTAAATGAACAGCAACGTAAAGATAATGAAAATAACACTCCCAGTTCCAATACTACTACCACAAATACTAGCACAAAATCTACCACTTTTGGAGCCACTAGCGGGCAACAGACACCAACACAGGTAACACCACCGGCTCCTCCGCCAGTATTTTGTGATATTTGCTCAAAACGTTTTACCAATGTCTTTGCTATGCGTCGTCATAGAGCCAAAGCTCATGAACAAAATTCCAATAATAGTTCCCAGCGCAATAGTCCATCTGAATCCTCTAACAACTCGTTAGAAGCAACAACACCTGCTACTCAAACGCCAGAAAGTCAAGCaaacaaacaatttcaaatgCCTGAAGGTTTTCGTCAAGATTTCGTTTTGGAACAGGAGGAGGTATCCTTTACACCACAGCCTCGCAAACTATCACCGCAGTCTCAACAACAGGCCCGTGAAGCCAACTTTGCCCATGATAAACTAAAGCGTTTGGGAGTTTTAAATCCAGAGGCTTTCTGTGAGATATGTTGCAaagaatattgtaataaatatttcttgcgTACCCACAAATGGAAACGCCATGGCATTTTTATGCCACCAGAGGAAGCGGAAAATCctcagaaattaaattcctggcCATTTATGAATATGCCTGGTATGCCGGTTAATTTAATGATGGCTCAACGTATGATGGCGGGTAATGAAACGCTGCCAGAGGAGTTggcacaacagcaacaacagcctCCTAAACGTATAAAGCTAGAACAACCCGATGAAGACGACGTTTTAATGAAAGAGACCAACAATGATGAAAATCAAGAAAATCGTAGTGAAAATAATCAGGTCTTAAGCGTACCCTCCACTCCTGAGCCCAATAAATTATTGGCCGATAGTCAAAGTATGGTGCAAAGTCCTGAAACTGCCATGGGTTTACAAAATCTACAGAAACTGCAAACCATGATCCagcaattaaatgatttaaatggcAAACGTCCGGTAGCTTGTCATTTGTGTGGGCGAGAAATGGAAAATCAATATGCTCTGCAGGCTCATATAATGGCTGAGCACAGTGGTGGTATGGAAGCAGCCATGCCACCTTTAAATTTTCCCTCTCAGCTACTAATGCAACAACAAGCTTTGCTCAAACAGTCTCCCAATGGTTCACCCAGTTCTTTGATGCCTCTTATGGCCGGAATGGCTGGTTCGGGAGAATTACGTTGTACTCCCTGTGACCGAGAATTTACAAATTTGCCagaatttcaaaaacatatcGCTGAAGTTCATTTGCTTACGAATACCTCGGGTAGCCCTTTACGTGAGGGTTTTGTTACGCCCGAAAGACCGATTAATCCTGCTATGGCTCAAACCACAAGACCTCCCTATACCATAACACCCACCAGCAGTTATTGTGAGATTTGCAATAAAGAATTgtgcaataaatatttcatgaaaACCCATATGCAACGTATGCATGGCATTGAAATAGAAAATGGTGCCCAAATAGGAGGCGTGGTATGCAATATCTGCAATAAGGAGTTATGTAGTAAATATTTCTTACGTGTCCATAAACATAATACCCATGGCATTATAGAGGATGGTGCCCCCTTGCCACAACCCAGACAAAATGGTTTGAATTTGGAAACGGCTTTGCAGCAACAAATGATGGAGACGGAGGGCCTAAATAGAAATCTCAATATGAGTCCTTTTGGCAGTGGAGGTTCAGAGGGTAAAAATGATAGCTATCCCACAACAGCTTATACCGAAATCTGTCCTATATGCACCAGACGTTTTCGTAATGTCAAATGGCTGAGAAATCATTTAATAAGTGAACATGGTCCGGCGGGCATGGACAAGGTAAGAGAATTGGAACAACAATATGGAGGCAGCTTAAGTAAACCCTCTAGTCCTACCTTGAAAATACCCAATGGCTCTAGTTCTTCGGGTTCTTCGGCAGCAGCTAGTGCTGTACCTTCACCAGCTCAATTGGCACAAGCTTTGCAAAATCTTAATGCCCAGCATTTACTACAAAATAtgcccaaaaataatatgaactCCAATTTTGGGGGAGAATCGAATCTACAATCGCCACAACTTAAAGAATATCAATGTTCCATGTGTCCATTTACCACACCCTATTATGCATTCCTATTCATACATGAACGTACCCATTCCATTATTAATAACAATGATCAGGAACAAGAACAGGAACACGAAACAGATAATGAGCaacatttcaaacaaaatgataaaaatgaaactgaacaactgcaacaacaacaacaaacgctaaaagaagaaaataaaagtttaaaacgtAAACACAGTCGTGATTTAAAATCACCCACAGAAATTGTTAATCTAGAACACGACGAGGAGCATGAAGAACCAACAAATGATAATAACAAACTTAATAAAGAAACGGAACTTAAGGACATTTTAACCAATGAACCCACTAATCTTTCTATGCGTACACCCTCACCCACCGAAATTACATCCACCACTACCAGTCGCGAGGAACTCACAAAACCTTCTACACCTAAAACTTTAATTCAACAAGATAATGCCATAAGTGAGAGTAAAGATTTTACAAATACTTTACTCTCACCCAAAGGTTTTAGAACAATAGCTTGCTCACCgatctttaataatttacaacaacaatttctACAAGAAATCTCTCAACAATCGGGTAAAATAGCTACATTTGCTGTACCAAGAGAAGATTTTACAGCAGCTACTTCAACACAAATGCAAGCATTTATTATTGAAGCCTCTCAGAATAACGAtgctgctgctactgctgctgATCATGAAGCAAATAATGAAGGTGATGATGTAAGTAAGAGATTTATGCCTGCTATAGTGTATTTACCCGTCAAAGAACGTTTAACAGGTAGCATGAAATTATCATTCAATTTAACAcctgtttaa
- Protein Sequence
- MAASIYATPPPDLKDNDDNEEHNNTTATTMAAVAAAANAAMQLQLLEAINDAAKKRRKQHNPSRMDEDTKYNSDMEEQQQQQQAYNNPYHTFCKECGENFENEFKLSLHMLQEHNDNAEGFSNNQSTAGDLTPLDILASVKVKLERPECESPSSNHNLEQVTNSSQEQQHNSSSATSNMLTNGKDQPQLTQPWMGAPTMPPMGFPFPPEAAAAAALQAGGYLPLLGVPGFPGVDGINRPPLRIFNPEAFSQQKLLNEQQRKDNENNTPSSNTTTTNTSTKSTTFGATSGQQTPTQVTPPAPPPVFCDICSKRFTNVFAMRRHRAKAHEQNSNNSSQRNSPSESSNNSLEATTPATQTPESQANKQFQMPEGFRQDFVLEQEEVSFTPQPRKLSPQSQQQAREANFAHDKLKRLGVLNPEAFCEICCKEYCNKYFLRTHKWKRHGIFMPPEEAENPQKLNSWPFMNMPGMPVNLMMAQRMMAGNETLPEELAQQQQQPPKRIKLEQPDEDDVLMKETNNDENQENRSENNQVLSVPSTPEPNKLLADSQSMVQSPETAMGLQNLQKLQTMIQQLNDLNGKRPVACHLCGREMENQYALQAHIMAEHSGGMEAAMPPLNFPSQLLMQQQALLKQSPNGSPSSLMPLMAGMAGSGELRCTPCDREFTNLPEFQKHIAEVHLLTNTSGSPLREGFVTPERPINPAMAQTTRPPYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRQNGLNLETALQQQMMETEGLNRNLNMSPFGSGGSEGKNDSYPTTAYTEICPICTRRFRNVKWLRNHLISEHGPAGMDKVRELEQQYGGSLSKPSSPTLKIPNGSSSSGSSAAASAVPSPAQLAQALQNLNAQHLLQNMPKNNMNSNFGGESNLQSPQLKEYQCSMCPFTTPYYAFLFIHERTHSIINNNDQEQEQEHETDNEQHFKQNDKNETEQLQQQQQTLKEENKSLKRKHSRDLKSPTEIVNLEHDEEHEEPTNDNNKLNKETELKDILTNEPTNLSMRTPSPTEITSTTTSREELTKPSTPKTLIQQDNAISESKDFTNTLLSPKGFRTIACSPIFNNLQQQFLQEISQQSGKIATFAVPREDFTAATSTQMQAFIIEASQNNDAAATAADHEANNEGDDVSKRFMPAIVYLPVKERLTGSMKLSFNLTPV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01261486;
- 90% Identity
- -
- 80% Identity
- -