Preg020306.1
Basic Information
- Insect
- Phormia regina
- Gene Symbol
- topi
- Assembly
- GCA_001735585.1
- Location
- MINJ01186076.1:41879-44578[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 2.4 2.5e+02 3.4 1.2 2 20 186 203 185 205 0.88 2 11 4.3e-05 0.0046 18.3 3.4 1 23 301 323 301 323 0.97 3 11 0.0077 0.81 11.3 0.3 2 23 353 374 352 374 0.96 4 11 0.054 5.6 8.6 0.1 2 19 440 457 439 459 0.94 5 11 8 8.4e+02 1.8 0.2 1 20 467 486 467 488 0.91 6 11 0.087 9.2 7.9 1.3 1 22 508 529 508 532 0.90 7 11 6.7e-07 7e-05 24.0 1.9 1 23 589 611 589 611 0.95 8 11 0.0039 0.41 12.2 1.1 1 23 617 642 617 642 0.95 9 11 0.58 61 5.3 1.7 1 23 648 670 648 670 0.88 10 11 8.4e-07 8.8e-05 23.7 0.3 1 23 676 698 676 698 0.98 11 11 0.015 1.6 10.3 3.8 3 23 706 727 704 727 0.96
Sequence Information
- Coding Sequence
- ATGAATTTAAATGAAGAAGACTTTAATTCATCTGATGCTTGGCTTTCGGAGTTATTATTTGCtcaattaaaagatttaaactCTGATTATAAAGAGACAAATCCTCCAACAGATTTTTTGCTTAGTGAAACTTTTACGAATTGTACAAATAGCATGCCATTACTCGATGACGATATTCCTCTGCAAGACTTAAAACCATCTCCTTTAGATACATTCGAGACTGAACTTAAAGTTAACACTTTTACTACTACTTATGATATAAACGAGGAAGTTTTGGATTTAAGTCAAATGCCTTTAAAAGTGCGCAATGTAGAAACTGCGACGTCGGAAGGAAACTTAATAGATTTTGTAGAAAACATACCATTAATACCGCCCTCTGTCATTCCAAATGTAGAATCTGTTCTTGGAACAAAACATGACTTGCGTTCATTTAATTCTAATGAagaagaactaaaaatattacaatttttagaaaCTCAGCCAAAAGAGCAATTAATAGCAACGGATCCTTCGATATCTTCATTTGTACCATCAACATCAACATATAAGATAATTAAATGTgcaaattgcaattttatatttaataataacgaATTTCAATCTCACGTTTGTGATTATGATGAAGATCACAGACTGATAGTTCCACAAATTCCGAAAATTAATTCATCTTGCAAACCTACTAAAGAAGAAATCCCTTTGCTACCAGCTGAACCGCCATGTATACGCTTACTAAGAGAAAATCAAATACGCATTAGACGGTTTCTAAAGGACGAATTAAAGTATGATGTTAATAGTAACATAAATGCTTTCGGTTCTGCAACCCCTTCTACTTCAAATGGTATTACAAATGCGTCGAGTTCATCAAATACttcaataaatatcaaaaaacaaGATGGTCCCCATGAGTGCACAAAGTGCGAAAGAAAATTTGTACATGCTTCTGGATTATTGCGTCATATGGAAAAACATGCTTTAGATTTAATACCCACTACTAATACAGCAACTAATAATAAGAATGCAACTGCACAAGTTGGGGATAGTTTGCGTGTTGCCATCAAATGTACTTTATGTggtagaattttttttgatgCAAAAGAagctttaaaacatttgttttcacATTTTCCCGATTCAAATGTGGAAGAGTACGAAATGGATAACTGTGCTGACATTCCTTACGATGCATATATAGATGatgcattaaataatttaaaatcggaGgtTCAaggtatttcattttataactaCTCAATAAAAAGCTATCAAGAGGATAAACCCCCTGtatatcttaaaataattattttgagttGTATTTTACAATGTGAATTTTGTGATCTTGTATTTTCCGAAGTATCCTATTTATTTGTACACTCTGCATGTCATTTACCATCTAGAAGATTTGAGTGCTTTGCTTGTGATATTCATGTAAAAACATCGAAAGAAATTTCTACACACTGGCAAGCAGAATGTGTATTTATGcgtgaaaatttaaaagtccTTCAAGCTACTACTCAACGTTATTTCGTTTGTaatgtttgtgaaaataaattccCATCTATGGATTTACTACATGAACAtcgtTATACGTCGTATCATTTCTTTCCACGACTGAACAAAAATATTGGAGTACTACAATTGCCGTGTGAATATTGTGAAAGTATATTTGAAAATGCACAAGAATGTGTTACCCACTATGAGGAAAAgcattatagaaaatataaacgaGATAAGGATGGTGCAAATGGTCCCAATAAGACTAGGCAATATTTGTGTGATATTTGTGGTAAATCTTATACACAATCTAGTCATTTATGGCAACATTTGAGATTTCATCAGgGAGTAAAGCCATTTGCATGTAAGGAACCAGGATGTACTCGAAAATTTACAATTCGTCCAGATTTAAATGATCACATTCGTAAATGTCATACCGGCGAACGACCTTATCACTGTCTTGTATGTGGAAAGCGTTTTCTTACTGGTTCGGTTTTTTACCAACATCGTCTTATACATCGCGGCGAAAGACGTTATGAATGCGAAGCGTGTGGTAAACGTTTTTATCGGGCTGATGCACTAAAAAATCATCAACGAATTCATACTGGGGAAAAACCATTTGGTTGTCACTTTTGTACCAAAAACTTTAGACAACGTGGGGATCGTGACAAACATATGCGAGCCCGGCATTCACATTTGGATGCCAATGCTCGTCTGATGATGCAGATGCAAAAATTGCAGTTAGAAGCGGCAGCAGCTCAGGCTCAAGACTTGCAAAAGCTGGAGGCTACttcaattaatgaaaatatcccACCGCCTGAGATTGATTCCCCAAATATTTCTTACATTAGaaataacacaaatttaaatGACTTCTTTATGATGGGCAATGTTTTTGAGTCCATAATGTCCGATATTATGaattag
- Protein Sequence
- MNLNEEDFNSSDAWLSELLFAQLKDLNSDYKETNPPTDFLLSETFTNCTNSMPLLDDDIPLQDLKPSPLDTFETELKVNTFTTTYDINEEVLDLSQMPLKVRNVETATSEGNLIDFVENIPLIPPSVIPNVESVLGTKHDLRSFNSNEEELKILQFLETQPKEQLIATDPSISSFVPSTSTYKIIKCANCNFIFNNNEFQSHVCDYDEDHRLIVPQIPKINSSCKPTKEEIPLLPAEPPCIRLLRENQIRIRRFLKDELKYDVNSNINAFGSATPSTSNGITNASSSSNTSINIKKQDGPHECTKCERKFVHASGLLRHMEKHALDLIPTTNTATNNKNATAQVGDSLRVAIKCTLCGRIFFDAKEALKHLFSHFPDSNVEEYEMDNCADIPYDAYIDDALNNLKSEVQGISFYNYSIKSYQEDKPPVYLKIIILSCILQCEFCDLVFSEVSYLFVHSACHLPSRRFECFACDIHVKTSKEISTHWQAECVFMRENLKVLQATTQRYFVCNVCENKFPSMDLLHEHRYTSYHFFPRLNKNIGVLQLPCEYCESIFENAQECVTHYEEKHYRKYKRDKDGANGPNKTRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEACGKRFYRADALKNHQRIHTGEKPFGCHFCTKNFRQRGDRDKHMRARHSHLDANARLMMQMQKLQLEAAAAQAQDLQKLEATSINENIPPPEIDSPNISYIRNNTNLNDFFMMGNVFESIMSDIMN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01261382; iTF_01259560;
- 90% Identity
- -
- 80% Identity
- -