Basic Information

Insect: Phormia regina
Gene Symbol: mecom-a
Assembly: GCA_001735585.1
Location: MINJ01025619.1:1748-7086[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0028 0.29 12.6 0.4 9 23 1 15 1 16 0.92

2 7 1.3e-06 0.00013 23.2 1.7 1 23 22 44 22 44 0.95

3 7 1.5e-05 0.0016 19.8 4.9 1 23 50 72 50 72 0.99

4 7 0.00021 0.022 16.2 1.1 2 21 80 99 79 100 0.95

5 7 4.9e-09 5.2e-07 30.8 1.3 1 23 541 563 541 563 0.99

6 7 2.6e-07 2.7e-05 25.3 0.9 1 23 569 592 569 592 0.97

7 7 4.5e-05 0.0047 18.3 6.6 1 23 598 620 598 620 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0028	0.29	12.6	0.4	9	23	1	15	1	16	0.92
2	7	1.3e-06	0.00013	23.2	1.7	1	23	22	44	22	44	0.95
3	7	1.5e-05	0.0016	19.8	4.9	1	23	50	72	50	72	0.99
4	7	0.00021	0.022	16.2	1.1	2	21	80	99	79	100	0.95
5	7	4.9e-09	5.2e-07	30.8	1.3	1	23	541	563	541	563	0.99
6	7	2.6e-07	2.7e-05	25.3	0.9	1	23	569	592	569	592	0.97
7	7	4.5e-05	0.0047	18.3	6.6	1	23	598	620	598	620	0.98

Sequence Information

Coding Sequence: GTATTTTGTGATCCCTCGAATTTACAGCGACATATTCGTAACCACCACATTGGAGCCAGAAGTCACGCTTGCCCTGAGTGCGGTAAAACATTTGCTACTTCATCAGGTCTTAAACAGCATACGCATATACATTCCTCCGTTAAACCCTTTCAGTGTGAAGTTTGTTTCAAAGCCTAcacacaattttcaaatttgtgcCGACACCGACGCATGCATGCCGATTGTCGCATGCAGATAAAGTGTAGCAAGTGTGGTCAAAGCTTTAGTACGGTCACTTCTTTGTCGAAACATAAACGATTTTGTGATTCTACTAGTGTAACGCCAGCGGGTGTGGGTTTACCACCCAGTCTACAACATTCTTTGCATCATCAACAAAATCAACCTCAGACACCTACACAAACACGTTCTGCGGGAGTTAACGGAGCTTTAAGCAACAATATGACTACACCACCAAACCCATTCTTGTTCTGGCGTTCTACTTTCTTCCCTGCTTTTCCACCAGCTGCTGCTGCTTTTGGTTTGCAGGGTATGTTTCCCCAAGCGCCAGCCACACAAACTGCTAATTTTTCTCCCATGTTCTCCAAACCAAATGTAGACTTTAAGTTGCAGCAATTAAGAAATCAGCAGCAGCCCCCAGCTCCACCAGCCAATATCATCAatcataataacaatattaaaggAAACTCTTTAAACACCAGCAATCCTAAGGAGGTGGCTAACGTAGCTGGGGTTACCGAAACATTTGGTCTATATTTTCCGAAATTTGAAATGGAACAAAAATCTAAATCCGAAATGGATTATAAAGTTAAAAGAGAAAGAACTCCAACggataatcaattaaaaaatcataaacggGACTCTCAGCGTTTTAATTCGGATGAAGAGTCTTTGGAGgctaaagaaaagtttaaagtggaaattaaaaaggaaaatgaatCAAAACTAAGGAAAGAAGAAGATGAGGAAATATCCCTAAAACTGAATGAGGATGATAAgAAATCCATTGATATTGTCTCGGTTTCACCCCACCATGAAGCGGAAGCTAAAAGCTCCTACACCGAACTGCCTTTGGATCTTAGTGTTTCACGCAAAAGAAATAGCATGGACTCAAATTTTAGCCAAGAAGAACAGAAATCCTCCTCTAGAGATGACAACAACTCCTCTATAAATCTCAGAGAAATTAGTCCCATAGCACCAGAAGAATTAAGCAATGCTGAGAGTTATGATCAACCTCTGAAAAAACCCAGAATATTTAATTCCTCAGTTAATAGTAGTCGTACACCTACTGCCTCGCCAGGACCCACACCCTCTCCTTCACCGCCGTGCAATGTTAGCAGCACCGCAACACATGAGAATAATCCTGCTTCACTGCCCACTTGTCCCCGACCTATACATCCCATGTTACTTGATGAAATCTATCGTACACATGCATTGGAGTCTCAGTTTCCTCGGCCGCCGTTTCCTTTTTTAGGACTAATGGGCGAGCGGCCGTCTCTGGAGGCCAATGCATTACGCGCTAGAGAAGAACAATTTGCGGCCGAGCCCATGTTTCATGAAGCTTTACGAGGTCTATCCTCGGGTGCTCTACAAGTAGCTCAAGCTGGCAAGCTTAAAGATCGTTATACCTGCAAGTTTTGTGGCAAAGTTTTTCCACGTTCAGCAAATTTAACCAGACACTTAAGGACTCACACTGGTGAACAACCCTATACTTGTAAATATTGTGATCGTGCTTTTAGCATCTCTTCAAATTTACAAAGACATGTACGTAATATCCACAATAAAGAGAGACCCTTTCGGTGTCATTTATGTGATCGTTGTTTTGGTCAACAGACTAATCTAGATCGACACTTAAAAAAACACGAATCCGATACTACGGGTCTAGGTTTAGCCATAAGTGATTCGCCCAGTTCAAATGAGGCTGACCGTGAGGATTCCTATTTTGATGAAATACGAAATTTCATGGATCGTGTTACCTACAATGAGGATTTATATACACCCTCCAGTATAGGAAATGCTGAAAATGATACTGATTACAATGCCAGCGATAATGAATTGTCTGTCTCGAGACCTTCTTCGGCTGATTTaactaatgaaaataataaagctATAGATGCTAATGAAATCTTAGAggatgattaa
Protein Sequence: VFCDPSNLQRHIRNHHIGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHRRMHADCRMQIKCSKCGQSFSTVTSLSKHKRFCDSTSVTPAGVGLPPSLQHSLHHQQNQPQTPTQTRSAGVNGALSNNMTTPPNPFLFWRSTFFPAFPPAAAAFGLQGMFPQAPATQTANFSPMFSKPNVDFKLQQLRNQQQPPAPPANIINHNNNIKGNSLNTSNPKEVANVAGVTETFGLYFPKFEMEQKSKSEMDYKVKRERTPTDNQLKNHKRDSQRFNSDEESLEAKEKFKVEIKKENESKLRKEEDEEISLKLNEDDKKSIDIVSVSPHHEAEAKSSYTELPLDLSVSRKRNSMDSNFSQEEQKSSSRDDNNSSINLREISPIAPEELSNAESYDQPLKKPRIFNSSVNSSRTPTASPGPTPSPSPPCNVSSTATHENNPASLPTCPRPIHPMLLDEIYRTHALESQFPRPPFPFLGLMGERPSLEANALRAREEQFAAEPMFHEALRGLSSGALQVAQAGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHLCDRCFGQQTNLDRHLKKHESDTTGLGLAISDSPSSNEADREDSYFDEIRNFMDRVTYNEDLYTPSSIGNAENDTDYNASDNELSVSRPSSADLTNENNKAIDANEILEDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01194609;
90% Identity: iTF_01194609;
80% Identity: iTF_01194609;