Preg026133.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phormia regina
Gene Symbol
khdrbs2
Assembly
GCA_001735585.1
Location
MINJ01017863.1:2421-7678[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0058 0.61 11.7 3.4 2 23 552 574 552 574 0.93
2 18 0.0012 0.12 13.8 2.3 1 23 581 604 581 604 0.95
3 18 0.054 5.6 8.6 3.7 1 19 609 627 609 628 0.96
4 18 0.0032 0.34 12.4 1.4 1 23 639 661 639 661 0.94
5 18 0.00015 0.016 16.6 3.6 1 23 666 688 666 688 0.99
6 18 2.2e-05 0.0023 19.3 0.1 1 23 694 716 694 716 0.97
7 18 0.0076 0.8 11.3 0.4 2 23 722 743 721 743 0.97
8 18 0.027 2.8 9.5 0.7 1 23 792 815 792 815 0.93
9 18 0.0032 0.33 12.5 0.6 2 23 823 845 822 845 0.95
10 18 0.017 1.8 10.2 5.4 2 23 1023 1045 1023 1045 0.93
11 18 0.12 13 7.5 3.4 1 23 1052 1075 1052 1075 0.89
12 18 0.055 5.7 8.6 4.2 1 19 1080 1098 1080 1101 0.94
13 18 0.00077 0.081 14.4 4.7 1 23 1110 1132 1110 1132 0.97
14 18 0.0043 0.45 12.1 9.7 1 23 1137 1159 1137 1159 0.99
15 18 8.1e-06 0.00085 20.6 0.3 1 23 1165 1187 1165 1187 0.98
16 18 0.00048 0.05 15.1 0.9 2 23 1193 1214 1192 1214 0.97
17 18 0.034 3.6 9.2 1.5 1 23 1259 1282 1259 1282 0.93
18 18 0.0093 0.98 11.0 0.5 2 23 1290 1312 1289 1312 0.95

Sequence Information

Coding Sequence
ATGTCTTGTGAGGACGTTCCTACAGAAATGTCTTTAACTGGCGATGCTTATGAACCCGAAGTAAGCCAAGTTGCAAGGAATTTTTTAGAAGAGTTAGAAAAGGAACAAAATCGTTTGAATGAGAAGTTTCCAATTTGTAATCTTTTAATAGATGAAGcttaTGATCGCATCTATTCCATGGGACTTGTTCCCGGTCATGATTCCTATGCGGATGTTATAAAGCTAAAACCAATGAAACTTTCACAAAAAGTTTTAGTGTCCGTACTAGAATATCcagaattaaatttaactaataaaGTTCAGAGATTAAAAGGAGAAATCCTAAAAACTCTCGAAGGCGAAACTCAATGTCAAATTTTAATCAAGGGACGTAATTCCATGACTGACCAAATCAAGGAAGAAGAATTAAGATTGTCAAAAGATCCACAGCACGTGCACCttaaaaaagaattgtttttggaaattattactGAAGCTACACCAATAGAATGTTATACACGTATTGCCTATGCTTTAGCTGAAATACGTAAATATTTATTGCCTGAAACAAATGATAACCATGAAATCCTACCAGATGCAGTTAATAATGCAAGGGACCAAATCAAaattgAACAGTTCGAGGAACCTCCTTTAGATATTGACTTAAAAGAGTCCCACCTAGAAGCAACACCCCATTTAGTGGCAAAGACTGAAGCGTCTGACAGTAACAATCCATTATCTATAAGTTTAGCCGataaacttattaaattgtTGGATGAAACAGTTTTAAATCCCAACTTTCAATACTCAGAAAATGAGACAAAAATGGTAGCAAACCATATTGACGTTTTAAGTAGTTTTATGGTATCGAAAACTTCCGCCAAACATGTGTCACATGAAAACGCCAATATAACTAgtatagaaaacaatttaaaaaatataaatccaaCAACTTCTTCCGCTTGTTCCTCTTCTACTATTAACAAAATGGATAAAAAGAAAGGTAAAAGTGAAAAATTGGGAATATCATCAAAACgaattgtaaaaagaaaaataaccaaAGATTCAATTAAAACCaagagtattaaaattaaaatgaacaaaCTGAAAGCTATTAAAAAGAGAAACCTGGAAAAAGCTTTAGACATTAAAAAgcaaaaataccCGGGCATATTTTATACAAAGGATTCAGAAACAGATAAAATTGTAAAACgtaaaatctcAAATAAATCTAGTTTAAGTCACTTTCTTAAAAGACCCAATGCGGTCATAACAAATGATGCGGGTCAACAGGatattgatgatgatgatgatgagtatAAACCTTTTACAATTGAATATTTACAAGAAAATCCTACTGAGcttGTTTTCGAATTTACACCACGCGAAATCATTATCACTCTACTAGACAGTATGAAAGATTATCCTGTTTTATGGGAATTTCATGATGAACCCTACAATGAAAATTATAGCAATGCTATTGAATATTTGTGCGAAATAATGAACGACAAATGGTTGCTTAATATTGAACCAATACAAATGCATCGTAGCATTTCACGAGTATTAAGATTTTATCGTTTTCTCTTTCCATTCGATAGTATCGACAGTTTTACAGAGTATTTTGATAAATGTGCATACTTTTTGCCTGCTGCTGTCGTTGAAATTCCCAATGCCCGTTGCTCGCATTGTTATCGATGCTTCAAACGAGATAAAGATCTGATAGCCCACCTTTTAGCAGAACACAACTCTTTAAAATGGCCTTACAAATGCCCACATTGTCGTGAAAGTTTTCGCACTACTAATGAATATGAGTTGCACAAACAGCTGCCacattatttagaaatttttacttGTCAAGAATGtaacaagaaatttaattattattacgcTTACTCAAAACATTTCCCCCACCAAAAACCAGAATTACCACGTAATTATGTCTGTGATATTTGCCAAAAGGAATTTACATCCAAAAGAGTATTAGCCATGCACAAAGACCACCATCAAGAAAAACGTTATAAATGTCATTTATGTCCGAAAGCGTATTTTTCTAGGACGAGCTTAATGATGCATTTGAGAAAACATCGCAAAGAGTTAAATTATATATGTGATGTTTGTGGCCAGGGATTCGTTCAGCAGAAATATCTAAATGATCACATGGACGTACATACGGGATTTAAAGTCACTTGCAACATATGTAATTTACAGGTAAGAAGAGGTAATTTGTATCGCCATTTGCGTACTGTTCATGTGGCTTGTGAAGGTACCTTGGAGACTACCTTTAGAGCAAAAggatataattacaaaaaactatTAGACTTGGAAAATCGAGCGGTATCTGCTTTTAAACATGATTATCAGCGTAAAAGAAAATGTGACAATGGACCACGTCAATACgaatgtaaaatatgtaaaattcaaTTCGATCGCCTTAAGGTGCTTAAAGATCATAACAAAGAATTACATTCTGATGTTGTTCAAAAGCTGCCATGCAAAATGTGTGATTCAATCTTATCACAACTTGGCAATCTAAAGAGACATTATCGTAATAAACATAAGTTAACTGAATTACAAGTTTATGCCATAGTTGTCAGGAACATGGACGTAGAAACTGCATTAACTATAACATCCCCGGAGaaaatttccaataaatccAGTTTAGATCACTGTCTTAAGAGATCGAATGCTGAAACTTCAAAACCAGAAAAACAGGATATTGATGTTGACGAATATAAACCTTTTACAATCGAACATTTGCAGCAAAATCCTAGTGagcTGGTTTTTGAATTCGCACCACGCGAGTTAATTATCACCCTGCTAGAGAGTATGGAGTCATATCCAGTTTTATGGGAATTTCATGATGTACCATTCAATGAGGACTATAGCAAAGCTATTGAATATTTGTGTGAAATAATGAATGATAAATGGTTGCTTAATATTGAACCCCTACAAATGAGTCGCAGCATTACGCGGATCTTAAGGTTTTAtcgttttttatttccatttgataatattgaaaaatatatggagtATTTTGATAAATGTGCACTTTTTCTGCCTTCTACTGTAATTGAAATTCCTCATGCCCGTTGTTCTCATTGTTATCGATGTTTTAAAAGGGATAAAGAGTTAAAATCTCATCTTTTAGCCGAACATGACTCTTTAAAATGGCCCCACAAATGTCCACATTGTCGTGAAAGTTTTCGCACTATCGAGGAATATGAGTTCCATAAACGTCTGCCACATTATTTGGAAGCCTTTACCTGTCcgaaatgcaataaaaaatataatgaacatAAAGCATACAAAAGACATGCACACTATGAAAAATCTGACGTACCGCGAAATCATGTATGCGACGTTTGCCAAAAGGCTTTTAGACTTAGAGAGCATTTAACTACTCACAAAAGATATCacgaagaaaagaaatataaatgtcACCTGTGTCCATGTACGTATTATAGTTGTTCAAATTTAACAACGCACTTGAAGAAACATCGTAAGGAACTCAATTATATATGCGATGTATGCGGCAAGGCTTATGTACAATTGAAACATCTTCAGGAGCATATGGATATGCATACCGGTTTTAAGGTCACATGTAACATCTGTAATTTAAAggttagaaaatataatttaaatcgaCATCTGCGTACGGTTCATGTGCCATGTGAGGGCACCATTGAGAGTACGTTTAGAGCAAGaagttataattataaaagGGGACAGGCTACGCGAGTCTTTAATCCTGACAATATCAAACGTAAACGACGACCTGCAGACAAGCCGCGTCAATATGAATGTAAAGTTTGTAATATTCATTTCGATCGTCTTAAGGTGCTTAAAGATCATAACAAAGAATTACATTCTGATCTTGTTCAAAAACTACCATGTAAAATGTGCGATTCAATACTATCACAGATAGGCAACCTAAAGCGGCATTATCGTAATAAACACAAGTTacctgaatataaaattttcgcctttgTCGAAAAGGATATGGATGTAAATACGGTATTGGCAATGACATCTGATGAGGCTATGTTggaattaactaaataa
Protein Sequence
MSCEDVPTEMSLTGDAYEPEVSQVARNFLEELEKEQNRLNEKFPICNLLIDEAYDRIYSMGLVPGHDSYADVIKLKPMKLSQKVLVSVLEYPELNLTNKVQRLKGEILKTLEGETQCQILIKGRNSMTDQIKEEELRLSKDPQHVHLKKELFLEIITEATPIECYTRIAYALAEIRKYLLPETNDNHEILPDAVNNARDQIKIEQFEEPPLDIDLKESHLEATPHLVAKTEASDSNNPLSISLADKLIKLLDETVLNPNFQYSENETKMVANHIDVLSSFMVSKTSAKHVSHENANITSIENNLKNINPTTSSACSSSTINKMDKKKGKSEKLGISSKRIVKRKITKDSIKTKSIKIKMNKLKAIKKRNLEKALDIKKQKYPGIFYTKDSETDKIVKRKISNKSSLSHFLKRPNAVITNDAGQQDIDDDDDEYKPFTIEYLQENPTELVFEFTPREIIITLLDSMKDYPVLWEFHDEPYNENYSNAIEYLCEIMNDKWLLNIEPIQMHRSISRVLRFYRFLFPFDSIDSFTEYFDKCAYFLPAAVVEIPNARCSHCYRCFKRDKDLIAHLLAEHNSLKWPYKCPHCRESFRTTNEYELHKQLPHYLEIFTCQECNKKFNYYYAYSKHFPHQKPELPRNYVCDICQKEFTSKRVLAMHKDHHQEKRYKCHLCPKAYFSRTSLMMHLRKHRKELNYICDVCGQGFVQQKYLNDHMDVHTGFKVTCNICNLQVRRGNLYRHLRTVHVACEGTLETTFRAKGYNYKKLLDLENRAVSAFKHDYQRKRKCDNGPRQYECKICKIQFDRLKVLKDHNKELHSDVVQKLPCKMCDSILSQLGNLKRHYRNKHKLTELQVYAIVVRNMDVETALTITSPEKISNKSSLDHCLKRSNAETSKPEKQDIDVDEYKPFTIEHLQQNPSELVFEFAPRELIITLLESMESYPVLWEFHDVPFNEDYSKAIEYLCEIMNDKWLLNIEPLQMSRSITRILRFYRFLFPFDNIEKYMEYFDKCALFLPSTVIEIPHARCSHCYRCFKRDKELKSHLLAEHDSLKWPHKCPHCRESFRTIEEYEFHKRLPHYLEAFTCPKCNKKYNEHKAYKRHAHYEKSDVPRNHVCDVCQKAFRLREHLTTHKRYHEEKKYKCHLCPCTYYSCSNLTTHLKKHRKELNYICDVCGKAYVQLKHLQEHMDMHTGFKVTCNICNLKVRKYNLNRHLRTVHVPCEGTIESTFRARSYNYKRGQATRVFNPDNIKRKRRPADKPRQYECKVCNIHFDRLKVLKDHNKELHSDLVQKLPCKMCDSILSQIGNLKRHYRNKHKLPEYKIFAFVEKDMDVNTVLAMTSDEAMLELTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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