Basic Information

Insect: Phoebis sennae
Gene Symbol: zfh1
Assembly: GCA_001586405.1
Location: LQNK01001326.1:263176-274981[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.02 1.4 9.6 0.4 1 23 71 93 71 93 0.94

2 8 1.6e-05 0.0011 19.3 2.5 2 23 99 120 98 120 0.97

3 8 9.3e-07 6.5e-05 23.2 6.1 1 23 129 151 129 151 0.99

4 8 9.7e-05 0.0068 16.9 1.0 1 21 157 177 157 178 0.95

5 8 0.00085 0.06 13.9 1.2 1 21 441 461 441 462 0.93

6 8 7.3e-06 0.00051 20.4 1.1 1 23 752 774 752 774 0.94

7 8 7.4e-05 0.0052 17.3 7.8 1 23 780 802 780 802 0.98

8 8 0.051 3.6 8.3 7.1 1 21 808 828 808 829 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.02	1.4	9.6	0.4	1	23	71	93	71	93	0.94
2	8	1.6e-05	0.0011	19.3	2.5	2	23	99	120	98	120	0.97
3	8	9.3e-07	6.5e-05	23.2	6.1	1	23	129	151	129	151	0.99
4	8	9.7e-05	0.0068	16.9	1.0	1	21	157	177	157	178	0.95
5	8	0.00085	0.06	13.9	1.2	1	21	441	461	441	462	0.93
6	8	7.3e-06	0.00051	20.4	1.1	1	23	752	774	752	774	0.94
7	8	7.4e-05	0.0052	17.3	7.8	1	23	780	802	780	802	0.98
8	8	0.051	3.6	8.3	7.1	1	21	808	828	808	829	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCATACTTATATGGGAGTTGGTTGGTACGAATGCTTTGCGGCCGGTTGGCTCGCGGACATGAGGAGTAAGCAGGTCCCGACTTCCACTACGTCGGCCAGGCGGCTTGCTGCCATGATCCGTCCACTCGCGAGTGGGGGTTCGGACGGCAAGCCCGAGGAGGAGGACGAGCGGGGCTCCTCGCCGCTGGGCCCCGGGGGCCCCTTCAGCTGCAGCCAGTGCCGCGGCGCCTACCCCACGCGGGAGCAGCTGGAGAAGCACGAGACGCTGCACTCCCCGAGCACTCAGACTTGCAAGATATGCCACAAGAGCTTCGCCAATGTGTACCGACTGCAACGGCACATGATAAGCCACGACGAGAGCGCCAGCCTGCGCAAATACAAGTGCAACGACTGCGATAAAGCATTTAAATTCAAACATCACCTTAAAGAACATTTAAGGATACACAGCGGGGAGAAACCCTTCGAATGTGCGAACTGCGGGAAGAAGTTCTCTCACTCAGGGTCTTATTCTTCGCATATGACCTCCAAGAAGTGTCTCGTAATGAATCTCAAGATGGGACGAATCAAGCCGACTAATCCCGCCCTCAACCCCGACCGAAGTCCTTCAAGAAAGCGAGCGAATGCGATCGTCGCTTCTCAACTCAATAATAACATTACGCCGAACGGCAATTCATTTTTGCCGATACTACCCAAATATAACGAGGCAGCTGCATTCTTTGCATCAATGTCTGGGCAAGATGCGAACTATCACCGCCCACCGTTAGCTCAACCAGGTATCAATCCTTTCTACATGCCCCCAGGCATGCCAATGAGCCCCGAAAGTGGAATAGCTCCATACAGCTTCCCCGCTTCTTTAAGCCAATTATTCCAGCAATTAGCTTCACAGCAATATCAACAAAGAAAAATAGAGAGCCCTAACCTTAAACAAATGAATCCTTCCCTCGCTGATCCTGAGGATTTAATCGAAGAAGTGACAGAAGAAGACGATAAGAGATCTGAAGGAAGCGCAGAACTTGTGATGGATATAGAAGATGACGAAGCTGTATCCATTAAAAAAGAACAAAACTTAGAAAATGATTTACGACCACCTTCTCATAATTACGATTCCGTCCCTTTAAATAACAACGGCCCTGAAGTCGACAATAACCACACAGGTTTTAATTCAATATTAGAATCGGTCAGCGCTTCAGTTAGCAAACATTTTTTCAGAGCTAACATGGACAAGCTATCACCTGTATCCGGAAATACTTGTCCTAGCATAGAATCTCCAGCCACACCACATCTCATTATAAAAAACGAACCTGAGGATACTCATAGGTGTACAAAGTGTAATCTGACCTTTAATAATAAGAATGATTTATTGGAGCATGAAAAAGTACTCTGTGGAAGTGTGTTTCGTAAACACGAGAGCTTAGCCGCGCAAGTCGCGGAGACGGTAGCGTTGAACAGGCTAGAAGCTGAAATGCGGGCGTCCATACAGAGTGGCGTCAGTGCTAGCGAGGACGAAGACTTCGGGAAAGAGGACCGTGATGATAAGTCTCTACACGACAGTGATAGAAAAATAAGAGTACGCACTGCTTTAACCGAAGAACAACAGTCTGTGTTAAAGAAACACTACGCTTACAATCCTCGGCCGAATAGGGAAGAATTTAAGAAGATCGCTCAACAAATCGGACTAGATAATAGAGTGGTTCAAGTTTGGTTCCAAAACAACCGCGCGAGGGTCCGACGCATGTCCAACGCGCTCACTGTATCGGATCAACCTCTAGACTTATCCACAAAAAAGTCTAACGTCTCCGTAACATCTAGCCCTTCCCCTTCGCCTTGTAGCATTTCTGTAACACATTCCGATTCCGAAGAAGCGGTGAATTTAAGTCAGAAGTCCTCGCGAAGTACGACCCCGTATCGCAAGAACTACGTGAACACTTATCCACATTCCAATTGCTCCTCCTCATCTCTGACGGACTTCCGACTGTCGCCGTCGCCTGGGGAGACCCAGAAGCGAACGCTCGCAAAGATGGCAGTCAATCCATTAATACCTATGGATAAGCTTCTACAATACAATGATTTAGCTAATGGGCTTCTCGGCATGCACACACCGGACAATAGACAAGCATCGAGCCCGTTATACGATCGTTCAGTTTGGGGCGACGAAGTCAAACACCAAGCTGACTTCGACGATGACGCAACTGTACTTAAAAAGAGCAAGTTGAAAGCGACTGATATTAAAGAGGGAGAGGGACAATTCGTATGTGATCAATGTGACAAGACTTTTGTGAAGCAAAGCTCGCTGGCGAGGCATAAATATGAACATTCAGGTCAGCGACCCTACAAATGCATGGAGTGCCCCAAGGCCTTCAAACACAAGCACCACCTGACCGAGCACAAGCGCCTGCACACCGGCGAGAAGCCCTTCCAGTGCTGCAAGTGCCTGAAGAAGTTCTCCCACTCCGGCTCCTACAGCCAACACATGAACCATCGATTCGCCATTTGCAAGCCATACAGGGATTAA
Protein Sequence: MKVHTYMGVGWYECFAAGWLADMRSKQVPTSTTSARRLAAMIRPLASGGSDGKPEEEDERGSSPLGPGGPFSCSQCRGAYPTREQLEKHETLHSPSTQTCKICHKSFANVYRLQRHMISHDESASLRKYKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPTNPALNPDRSPSRKRANAIVASQLNNNITPNGNSFLPILPKYNEAAAFFASMSGQDANYHRPPLAQPGINPFYMPPGMPMSPESGIAPYSFPASLSQLFQQLASQQYQQRKIESPNLKQMNPSLADPEDLIEEVTEEDDKRSEGSAELVMDIEDDEAVSIKKEQNLENDLRPPSHNYDSVPLNNNGPEVDNNHTGFNSILESVSASVSKHFFRANMDKLSPVSGNTCPSIESPATPHLIIKNEPEDTHRCTKCNLTFNNKNDLLEHEKVLCGSVFRKHESLAAQVAETVALNRLEAEMRASIQSGVSASEDEDFGKEDRDDKSLHDSDRKIRVRTALTEEQQSVLKKHYAYNPRPNREEFKKIAQQIGLDNRVVQVWFQNNRARVRRMSNALTVSDQPLDLSTKKSNVSVTSSPSPSPCSISVTHSDSEEAVNLSQKSSRSTTPYRKNYVNTYPHSNCSSSSLTDFRLSPSPGETQKRTLAKMAVNPLIPMDKLLQYNDLANGLLGMHTPDNRQASSPLYDRSVWGDEVKHQADFDDDATVLKKSKLKATDIKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCMECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00357316;
80% Identity: iTF_01193497;