Ppap005623.1
Basic Information
- Insect
- Phlebotomus papatasi
- Gene Symbol
- -
- Assembly
- GCA_000262795.1
- Location
- Scaffold1:1100029-1106594[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0017 0.068 13.0 0.1 1 20 133 152 133 152 0.96 2 11 3.8 1.5e+02 2.5 1.4 2 19 164 181 163 183 0.83 3 11 1 40 4.3 3.2 2 23 186 206 186 208 0.91 4 11 0.0001 0.0039 16.9 0.4 1 23 213 236 213 236 0.96 5 11 0.024 0.92 9.4 1.1 3 23 244 263 243 263 0.97 6 11 4.4e-05 0.0017 18.0 0.2 1 23 274 297 274 297 0.96 7 11 0.021 0.81 9.6 5.2 2 23 306 328 305 328 0.95 8 11 0.02 0.79 9.6 11.5 1 23 334 356 334 357 0.95 9 11 0.26 10 6.1 0.4 1 12 363 374 363 385 0.76 10 11 9.3e-06 0.00036 20.1 4.0 1 23 391 413 391 413 0.97 11 11 4.8 1.9e+02 2.2 3.8 1 23 419 442 419 442 0.94
Sequence Information
- Coding Sequence
- ATGGATGCAAATTCCAATTCTGTCTGTCGGCTCTGTCTGAGGTCGAAGAAGCACCTTCAGTCGATTGTTGATGGTGCTTTTGAGGCAGTTTCCTACTTGGATGTTTATTCTGAATGCGTTGGGAGGACACTTGAGGACTTCCCTGAGTACCCAATGAAGATGTGTAGGAAGTGTGAGAATGAGATGCTTATAGCCTATCAATTTAGGCTGAAGTGCCTGGACACGGAGGAGAAATTGAGAGCTGCGACGGAACAGCCTGAATTTGTGGACGTCAAGGAGGAGCCGGAGGATGTGAGGGGTGAAAGTGATGATCAGGATGAGACTGAGGAGAAAGAGGAAGAAGTCCCAGTGCGTCGTCGTAGGAGTAAAAGTGCAGAAGGGGAAGAGGAGAAGAAGTATCCGTGTGAGATTTGTGGGAATCGGTATCCCAGTAGGAATTCCCTGAATGCCCATCGGTGGCATATTCATAAGCTCAGGCCACCCGTGATGCCGTGTAAACGCTGCGGAGGGAACTTCAAGACTCGCCAGGAGAAGAATGGACACGAATGCTTGAGGCAGTGTGAGCACTGCGGGAAGAATATCAGCGGAAAGCACTTTGCCATGCATCTCATGAGGCATACAAACACCAAGAAGGAATACAAATGCTCCCTCTGTCCAAAGGAATACTTCACTCCGGCGGATCTGTCCAAGCACAAACTCGTGAGTCACGTGAAGAATGAATTCACGCTGTGCGTCATATGCGGCAAGATGGTAAAGCAATCGAATCTGCATATGCATGCCAAGAGTCACCAGCCCAAATCCGAAGCCACCAAGAAGACCTTCCCATGCGAGGAATGCAGCAAAGTCTATTGCTCAGCAGCTAGCCTGAGGATTCACGTGGACACGATCCATTTGGGCATGAAGGTGCTGAAAGTGAAATGCCCACATTGTCAGATGGGCTTCAAAGAGCATTCGCATCGTACAGCTCACATCTACAAGTACCACCTGAAGAAGCCACTTTTCTCCTGTGTTCACTGTCAGAAGGACTTCTACCACAAATCCCACTTCAACAATCACAACAAAGTCCATCATTCCTTTGAGAAACTCTACCACTGCAGCATATGCAGCAAAGCTTTTGCTCTCGACTCACGGCGAAAAATGCACGAGGCACTGCATTCAGATGAACGTCGTTTTATGTGCTCCACCTGCTCCAAATCCTTCAAACTTCGCAATCACTTGATCCGGCACATGCGAGGTCACACTGGCGAGAAGATCTTCTGCTGTCCACACTGCAGCAACCTCTTCTATTCCATTCGCAGTGTCCGGGGGCACGTGAAGAGGGATCATCCGGATAAGGAAATGCCACCGCCTGGGACAATTCTGTCCAAGAAAAAACTCGATCAATTGGCAAAGCAACGAGAGCTTGAACAATCCCTCCTAAACATTCCAGTTGATCCACAACTCCTGCCCACaaaaagtaactaa
- Protein Sequence
- MDANSNSVCRLCLRSKKHLQSIVDGAFEAVSYLDVYSECVGRTLEDFPEYPMKMCRKCENEMLIAYQFRLKCLDTEEKLRAATEQPEFVDVKEEPEDVRGESDDQDETEEKEEEVPVRRRRSKSAEGEEEKKYPCEICGNRYPSRNSLNAHRWHIHKLRPPVMPCKRCGGNFKTRQEKNGHECLRQCEHCGKNISGKHFAMHLMRHTNTKKEYKCSLCPKEYFTPADLSKHKLVSHVKNEFTLCVICGKMVKQSNLHMHAKSHQPKSEATKKTFPCEECSKVYCSAASLRIHVDTIHLGMKVLKVKCPHCQMGFKEHSHRTAHIYKYHLKKPLFSCVHCQKDFYHKSHFNNHNKVHHSFEKLYHCSICSKAFALDSRRKMHEALHSDERRFMCSTCSKSFKLRNHLIRHMRGHTGEKIFCCPHCSNLFYSIRSVRGHVKRDHPDKEMPPPGTILSKKKLDQLAKQRELEQSLLNIPVDPQLLPTKSN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -