Basic Information

Insect: Phlebotomus papatasi
Gene Symbol: ush
Assembly: GCA_000262795.1
Location: Scaffold22:244000-339930[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0046 0.18 11.7 0.1 1 20 193 212 193 214 0.93

2 9 0.00029 0.011 15.4 0.7 1 23 253 275 253 275 0.98

3 9 0.018 0.7 9.8 1.4 2 21 301 320 301 321 0.92

4 9 0.049 1.9 8.4 3.3 2 21 613 632 612 633 0.94

5 9 0.0063 0.24 11.2 0.0 3 21 682 700 680 701 0.91

6 9 0.00054 0.021 14.6 0.1 1 23 748 770 748 770 0.99

7 9 0.013 0.51 10.2 1.3 1 23 776 798 776 798 0.99

8 9 0.0031 0.12 12.2 1.0 1 23 839 862 839 862 0.95

9 9 0.13 4.9 7.1 1.0 2 21 977 996 976 997 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0046	0.18	11.7	0.1	1	20	193	212	193	214	0.93
2	9	0.00029	0.011	15.4	0.7	1	23	253	275	253	275	0.98
3	9	0.018	0.7	9.8	1.4	2	21	301	320	301	321	0.92
4	9	0.049	1.9	8.4	3.3	2	21	613	632	612	633	0.94
5	9	0.0063	0.24	11.2	0.0	3	21	682	700	680	701	0.91
6	9	0.00054	0.021	14.6	0.1	1	23	748	770	748	770	0.99
7	9	0.013	0.51	10.2	1.3	1	23	776	798	776	798	0.99
8	9	0.0031	0.12	12.2	1.0	1	23	839	862	839	862	0.95
9	9	0.13	4.9	7.1	1.0	2	21	977	996	976	997	0.93

Sequence Information

Coding Sequence: ATGTATCCGAAGCTTTTTGGATTGCTCACAAGGAGAAAATTACCAGGTCAAGCCATCTCAGATGCCACAAGACGGGACGACGAAGACTACCAGGGCGAAGAAGGAGGCGGAGGGGGGCTCCAGAGCGATGGTCAGGGATCACCATCGACTGAAGTTGGTCAGTCAACATCTCCCCGTAGTCACTCAGAGTCCCCACAATCACCCAGATCGCCCTCATGCAGTACCCCAGCTCCCTCTCCTCAAGAAATCCTGACTGAGGCGGCGCCGGATCGTCCGTCGCCGCCAGATAGTGTAATAGAAATGAACTGTGGTCGAGACACTCCACTCCCAAAGCCCACACTACGCCTCAATACAAAACTGGCGTCTGATCCAGCCCTACAGCCCGAAGCCAAGGATCTTAAGGATACCATCAGACTGAGCAGTGAGGATGAGAAGACTGTGGACAGGGTGGAGCAAGAGGAAGCGGAGAAGAAACTCACAAAATCCTTAAAAGATATTCGAATGGAAAAAGTCATTCATCCAACAAGAACGTCCCCTGTTGATGCTCTTCCAGCCGCAGTACCCAGAATGCAGGTCTTTACATGCGGACCCTGCGGCATTAGATTCTCATCCCTGTCCACCCTAGAGGCTCATCAAACATATTACTGTTCTCATCGGAAGGAACCAGATGATGCAGCAGGAGCTAAAGGAACAACTGCAGCAGATTCTCCGGGTAGTCAGGAGCCACCAGTAAAAGCACAAAGAACTGGGAAGCAATACGCATGTAGTCAGTGTTCGTATTCAGCAGACAAGAAAGTCTCCCTGAACAGACACATGCGAATGCATCAGACTTCGCCAGCACCTAGCTCTACCACATCTAATGGCGATGAGCCACCTAGTCAAACAGCTCAAGTCGACCGCTACTGCTCCGACTGCGACATCCGCTTCTCTAGCACCAAGACCTACAGAGCACACAAGCAGCATTATTGCAGTTCCAGGCATAGGGATGGGCAAATTGTCAACCATGTTTCATCCAAACCTCCATCGATCGTCAAAGGTGGTTCACAGAGTCCACCTGAAATTGCTAAGAGTCCCCCAACGGCTCAACCTCAGGCTTACCTAGCTCTACCAACTAACCCAATCGTGATTGTACCATGTTCCGTAATCCGTGGCGCGAGCCTCTTACCAGGACCTCTTACATCCCTCGCCCAGAATGTTACAAATCCCGAAGCAACGTGCTTCCTACTTCAGAATGGAGCTCTAACGCCGATTGCGCAAGCGCTTTCAGTGCAGGCCCCAATAGTAAATCAACCGCCTTCACGTGGTCCAACTCCTGCATCTGAAAAGGACAATGGCGTAACCGTCCCAGACGTTCTACGCGTAGTCAACAAGAAGGACCACCAGCAACTCCGTGACCCTACTATCCCGCTTGATCTCTCAGTTAGACGCTTGCCTACATCTCGAGAACGTTCGCAGTCGTTCTCCTCCGTAGCTTCTGCAGACGCCATCAGTCGTCCTGATGTCGATGCTAACGCAGAAGGCAAGGAAAATGTCTCCGTAGGCAGTGATTCCCTAACACCGGAACAAATTGTCTGTGCTCCATCTCTCCCTGGAAGTCCCCCACTAACTCCGTCTCCGAAGCGACGTTCCAATAGTCCCAGAGGTGGCAGCATTTCTGTATCACCCAACTCTATCCTGATGCGTCCTCTTCTGCCGGCAGATCTGACTCCCCAGGTACTTGTACGTCTCAATAATGAAGCTGTTCTGCCACCCCTGGTTCCTGGTCCTAGTCCAGGAGCTCCTCCCGCAAATGCCGCTCCTCTGCCACCACAAATCTTTGTGAAGCAGGGCGTGTCCAAATGCAAGGAATGCAACATTGTCTTTTGCAAGTACGAGAACTATTTGGCCCACAAGAAACATTACTGCTCAGCACGGAATTTAGATGATCCAGAAGGGGCAAAAGTTAGTCCGCCTGTTAGTCCTACAGCTACTAGTCCTCTTGCGCAAACAGGACCTCAGGCGGTGACTGTTGCAGGAGGAGGATTGGCCTATCAGCAGCTTATTTGTGCTGCTTGTGGGATCAAATTCACTTCCCTAGACAACCTAAGCGCCCACCAAATGTACTACTGTCCCAAAAGAGTGGAGCTCGCAGTTCAGCAATCCCTTATCCAGAAAGATCGCTGTACTAAATGTAAAATCGTTCATGATCCCAATATTCCCTGCCCATCGTCTCATGTGGGCAGCTCCGGTTCAGCCGGTGGCTACAAGTGTCCCATCTGTGACGTCGTCAGCACGAATGCTGCCGAATCCCGACGTCACATGGAAACTCATGGAGGAGTAAAGGCTTTCAGATGCTCAATTTGTCGCTACAAAGGGAACACCCTGCGTGGAATGAGAACCCATATTCGAATGCACTTTGAAAAGAAAACCACTGACTTCAACGAGGAGAACTACATCACATGCATCCTCGAGGAAGATGGTGTGGAAATTCCACCAGCAGCCCAAATAAATCCTGAAACACTCCAGCCACAGATGCATTCTTGTGATCTCTGCAACTACTCATCCAGCTACAAGGGCAATGTGGTACGACATATAAAATTAGTACATTCTCAGACCAATCATCAGTCAAATTCACCAAGTATTGGAGAAGGTGGCGAGAGTCTCATTCACAATGGCAACAGCAGTGATTTATCCGGATCTGGGACATCCATCAAAATTTCCCTGCCGCCGAGAAACACGTCCCGACCTTCGAGTCAAGTATCAGTGTCAGTGAAAATAGAACCTGAGCAGGATTTCGCCAAGACTGAGGACGAACCGGAGCTCGTAATTGACGACAGTGATGTTGTGGTCAAAGTGGAAGCCAGTGATCGCTCAGAGACTCCTCTAGGGCCTCCACCGCCCCGGAAAACTCCCTCTCCGGACGACTCAATGGTCACCGGTGGACCAAAGTACTGCAAAACCTGCGACATTCGCTTCAACTATCTCAACACCTTCATTGCCCACAAAAAATTCTACTGCAAAGGTACCAATGTTGATGCTCTGTTGCCGGAAAGAATTGTGGATGTCACCACAAATAACACAAGTCCCAAGAGATCACCAACTTCCCCAGCACCAGCAGTTGTAACAACTTCAGTGCTCTAA
Protein Sequence: MYPKLFGLLTRRKLPGQAISDATRRDDEDYQGEEGGGGGLQSDGQGSPSTEVGQSTSPRSHSESPQSPRSPSCSTPAPSPQEILTEAAPDRPSPPDSVIEMNCGRDTPLPKPTLRLNTKLASDPALQPEAKDLKDTIRLSSEDEKTVDRVEQEEAEKKLTKSLKDIRMEKVIHPTRTSPVDALPAAVPRMQVFTCGPCGIRFSSLSTLEAHQTYYCSHRKEPDDAAGAKGTTAADSPGSQEPPVKAQRTGKQYACSQCSYSADKKVSLNRHMRMHQTSPAPSSTTSNGDEPPSQTAQVDRYCSDCDIRFSSTKTYRAHKQHYCSSRHRDGQIVNHVSSKPPSIVKGGSQSPPEIAKSPPTAQPQAYLALPTNPIVIVPCSVIRGASLLPGPLTSLAQNVTNPEATCFLLQNGALTPIAQALSVQAPIVNQPPSRGPTPASEKDNGVTVPDVLRVVNKKDHQQLRDPTIPLDLSVRRLPTSRERSQSFSSVASADAISRPDVDANAEGKENVSVGSDSLTPEQIVCAPSLPGSPPLTPSPKRRSNSPRGGSISVSPNSILMRPLLPADLTPQVLVRLNNEAVLPPLVPGPSPGAPPANAAPLPPQIFVKQGVSKCKECNIVFCKYENYLAHKKHYCSARNLDDPEGAKVSPPVSPTATSPLAQTGPQAVTVAGGGLAYQQLICAACGIKFTSLDNLSAHQMYYCPKRVELAVQQSLIQKDRCTKCKIVHDPNIPCPSSHVGSSGSAGGYKCPICDVVSTNAAESRRHMETHGGVKAFRCSICRYKGNTLRGMRTHIRMHFEKKTTDFNEENYITCILEEDGVEIPPAAQINPETLQPQMHSCDLCNYSSSYKGNVVRHIKLVHSQTNHQSNSPSIGEGGESLIHNGNSSDLSGSGTSIKISLPPRNTSRPSSQVSVSVKIEPEQDFAKTEDEPELVIDDSDVVVKVEASDRSETPLGPPPPRKTPSPDDSMVTGGPKYCKTCDIRFNYLNTFIAHKKFYCKGTNVDALLPERIVDVTTNNTSPKRSPTSPAPAVVTTSVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01191527;
90% Identity: -
80% Identity: -