Ppap002477.1
Basic Information
- Insect
- Phlebotomus papatasi
- Gene Symbol
- Mtf1
- Assembly
- GCA_000262795.1
- Location
- Scaffold24:421502-428695[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 6 0.00013 0.005 16.6 1.6 1 23 125 149 125 149 0.98 2 6 1.5e-05 0.00059 19.5 0.4 1 23 155 179 155 179 0.98 3 6 5e-06 0.00019 21.0 0.3 1 23 185 209 185 209 0.98 4 6 3.4e-07 1.3e-05 24.7 4.5 3 23 216 236 214 236 0.97 5 6 1e-05 0.00039 20.0 1.3 1 23 242 266 242 266 0.97 6 6 6.6e-05 0.0026 17.5 2.3 1 23 272 296 272 296 0.96
Sequence Information
- Coding Sequence
- ATGGCTGCTGAAGGAAGTGCTGAGAAAAATACCGTGAATATCCTGGCTGAGACAGGAGAGAGGATTGATTTCCAGCTAGATGACTCGGACTTGCAGGACTGCATTGATAATCCTTTAGATATTGCTGATCTGCAGCGAGTGATTGAGCAGGGGACGTCGTTTAGTGACAAGGCCTTTCCGGACGATGTTACGTCCTCTGAAAAGGTCTTCCCGGACACTAAGGCGGAGCAGCTGAATGGTTACATGGAGCATACAATCCTTCCTGATGAAATATCCCTCTGTATACGACCCGGAGCTAAACACAAACTCAGCGGAGAGCCCTCGCATGCGACGATTACAATCGAGGGCTCCGAACCGCACATCTTGGCGCGATATCGTTGCAACTACGACAGTTGCTCGAGAAGCTACAGCACTGTGGGCAACTTGAGGACACACCTAAAGACACACAGAGGGGAATATCGGTTTAAGTGTACACAGGAAGGATGTGGCAAGGCTTTTCTCACTTCCTACAGCCTTAAGATTCACATTCGTGTGCATACGAAGGTGAAACCGTATGAATGTCCTGAGGGGGGATGTGAGAAGTCATTCAATACGCGATACCGCCTCAGGGCGCATCTTCGGCTGCACAATGGGGAAACGGTCAATTGTACAATGTGCCATAAGTTTTTTACGACTCTCAGTGATCTTAAGAAGCACATGAGGACCCATACGCAAGAGAGACCGTACAAATGTGCAGAGAATGGATGTGGGAAGGCTTTTATTGCTTCCCATCATCTCAAAACTCATATCCGGATCCATACAGGAGAGCGTCCGTATTCATGTCGCGAAGATAATTGCACAAAGGCATTCAGTACGGCTCATAGCTTAAAGTCTCACGTGAAGACGCATAAAAAGTACAATCAGGTGAAGAAGGAAGTTGCACCGGGTGAGGAAATAGTCAAGGGGAGAAGCAGTGAAAAATCTCCGGAGAAATCCGATCCAAAAAGTGAGGTTAAATCCACGGAGAAGAATACAGAATCCTCTGAACAGTTCAATTTGGAGACATCAAAAGCAATTGAAATGGCCATAGCTAATGAGATTGAGATCCCATCACCATGGATAGATGTCTCAGAGCTAGCTTCGAAGCCCATCATGCCAGCTGTTCCGGTCACTCCAGCCTGCATGGCCCTGCCGACTGGAGTAACTTCCTACGTCGATCTTCCCTTCAATATCGCCTCAGCGGACACGGATTTCATCGATTCTTCCTTTGAGAGTGAACAAATGTCCTTTGAGCAACTCTTTGGGTCTCCAGGCAAGGACAAGGGGACTCGGGAGGGTGTCGATACGGATACCGGAACTATGGATATTGGTACAAATTTCTCTCCATTACCCACGGATTTGGGCAATAAGCAGCAAATTGAGGCTGAAGCTCTGCTCAATGAGATCTTCTTTGAGACACTAAATACACCAACATCGAATCTGCCCAGCCAGGGAAAGATTATGATGTCTGAACAATTTGAAAATATGCAGAATAATGTGGAGTTTCCGGAAACTGTCACGGGGACCAGTGCTGAGATGTTAATGGTCAGGACGGCTTCGGTTCTTGGAAATGGGAACAATACCAGGGCTCTTCAGGTAAGGCTTCTGATAAGACTCAGAGATTTGTAA
- Protein Sequence
- MAAEGSAEKNTVNILAETGERIDFQLDDSDLQDCIDNPLDIADLQRVIEQGTSFSDKAFPDDVTSSEKVFPDTKAEQLNGYMEHTILPDEISLCIRPGAKHKLSGEPSHATITIEGSEPHILARYRCNYDSCSRSYSTVGNLRTHLKTHRGEYRFKCTQEGCGKAFLTSYSLKIHIRVHTKVKPYECPEGGCEKSFNTRYRLRAHLRLHNGETVNCTMCHKFFTTLSDLKKHMRTHTQERPYKCAENGCGKAFIASHHLKTHIRIHTGERPYSCREDNCTKAFSTAHSLKSHVKTHKKYNQVKKEVAPGEEIVKGRSSEKSPEKSDPKSEVKSTEKNTESSEQFNLETSKAIEMAIANEIEIPSPWIDVSELASKPIMPAVPVTPACMALPTGVTSYVDLPFNIASADTDFIDSSFESEQMSFEQLFGSPGKDKGTREGVDTDTGTMDIGTNFSPLPTDLGNKQQIEAEALLNEIFFETLNTPTSNLPSQGKIMMSEQFENMQNNVEFPETVTGTSAEMLMVRTASVLGNGNNTRALQVRLLIRLRDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01191510;
- 90% Identity
- -
- 80% Identity
- -