Basic Information

Gene Symbol
-
Assembly
GCA_000262795.1
Location
Scaffold34:186722-221194[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00026 0.01 15.6 3.4 1 23 234 256 234 256 0.98
2 11 0.0016 0.064 13.1 9.5 1 23 262 284 262 284 0.96
3 11 6.8e-05 0.0027 17.4 6.5 1 23 290 312 290 312 0.98
4 11 0.00039 0.015 15.0 2.3 1 23 318 340 318 340 0.95
5 11 6e-06 0.00023 20.8 0.7 1 23 346 368 346 368 0.97
6 11 8.4e-06 0.00033 20.3 0.2 1 23 374 396 374 396 0.98
7 11 0.00014 0.0053 16.5 0.9 1 23 401 423 401 423 0.97
8 11 1.3e-05 0.0005 19.7 0.1 1 23 429 452 429 452 0.96
9 11 0.00047 0.018 14.8 0.1 1 23 557 579 557 579 0.97
10 11 0.018 0.69 9.8 3.3 1 23 665 687 665 687 0.96
11 11 0.0061 0.24 11.3 5.2 5 23 700 718 691 718 0.89

Sequence Information

Coding Sequence
ATGTGTGCGGCTCAGAGCAATCCACCAGCCACTTTTGGATACACTTGGGGCTTTGCTGATAACACAAGGACCGAATCTGTTGTTGAAATCTCACCCAATATCAACTATACGGTGAGTGAAACGATGCCATACTTGCAGTTGACCGATTCTGGTGGGATTACGGTGCAGAAGGATTCAAAAGGAGCTATAGCTCATACAAACAAAGGAGTTGTTCGAAGGATGATTGTCATGAATGAGCCTTTCCCGCAGACCACAACACAGAGGGTTATTACAACAGGCAGTGGAGCCACCACAGTCACTCACCACAAGAAACATGATGTGCTGACCAATGGAATAATTGATACAAAAGCCCAGACAGTTTTGACAACAGCCAGCGGAAAGATGCATTTTATGAGTCCCATTGGACCACTTCAACTCACAGCAGAGGAGTGTAATGAGATTTTGGCTAAGAGAGCCATGAGTGCTGCCCAAACTCAACATACCACAATAGCAACAACTACAGATGGGCATCATGCAGGTTGGTCTGGAATCGCCGTACAAGTGCAAAAAGTTATTCAGGGTTTGGAGGAAAATGATGATTCACAGACAGCCTCATCGACACATTGCAAATTGGAACCCGTTATGAGTATCTCACCGAAATTGGAGTTCATCGAACAACCAAGTAGCCATGAGGAAGCCATACCGAAGAAAGAACGTCCCTACTCGTGTGATGAGTGCGGCAAATCTTTTCTGCTAAAACATCATCTTACGACTCATGCTCGGGTACATACGGGCGAACGGCCGCATGTATGCGTCCACTGTGGCAAGAGCTTTGCCCACAAGCACTGTCTCAACACACATCTTTTGCTGCACTCTACGGATCGACCGTATCAGTGCAATGAATGCAAGAAAAGCTTCACACTGAAGCACCATCTGCTTACGCATTCACGTGTCCACAGTAGGGAACGTCCATTTGTGTGCCAGGAGTGTGGGAGATCGTTTCCATTGAAGCGTCATCTCGTCACCCACAGCAAATTCCATGCCGGCGAACGACCATACGTGTGTGATGATTGTGGTGAGAGTTTTGCACAGAAGGAGCACCTTGTAATGCATTCACGTTTTCACGGATCCCTGAATCCTTTTGTCTGCCAAGATTGTGGTGCAACGTTTCCACGGAAATTCCAGTTAGTGAACCATGGACGAATTCATGGACGAGTGCCCCACTCCTGTCCCATTTGTGGTAAGGAGTTTCTCCAGAAGCGCACTTTGGTTGCTCACACTCGTCTCCATACGGGTGACCAGCCATATCCATGCACAATCTGTGGAGAGGGTTTTCGCACGAAGCCCGAACTCAATCAACACAACCGACAAGTCCATGGCGGTCAATCAACCACAACAACCGCGACAGCTAATACAATTGTGGCAACGAATGCAATTGTTGCAAACAATCAACACGCACAGCATGTTCAGGTGCATACATCgcagcagcaacaaccacagcagcagacgcatcaggcacaagcggcagcacagcagcagcaacaacagcagcagcaacagcaacagcagcagcaacaacagcagcaacagcaacaacagcaaacggtgactgtggtgaccaacacaaacaacGGACTAGTTACGACGATAGCAACCCCTTCGACAGCAGCAGAGGCGGCCCGTCCGCAATTTGCTTGCCGTGAATGTGGCAGTGCCTTTAACAGTCGTGAAGCCCTTGCTCTCCATTTGCGACTTCATACCGGAGACAAGAGCCTCATGACAGATCTATGTGCTCTCACAGCAGCAATTCCTGGACATTTCTTAAATACCAACATTAACTCCGGAACAACTGTCGTGGCTGCAAATCCCGCCGTGGTATCTCCTACACCCGTGCCCGTGCAAATAATAACATCGTCGGGTCAAGTGGTGAGTCAAGCCATGGCGGTGCAGAGTGCACCTCAACCACAACAAACGGTGGTGCAGACGGTAGCACCTCAGCAGAAGCCCAAGACGCACTTCTGCAGCAGTTGCGGTAAGGGATTTGCTGCCAAACATGGCCTCCTGCAGCACAATAGACGTCATACAAATGGAAGTTGCACGCTGAGAACACATGTTTGCGAATGCGGAAAGGCCTTCTTCCAGAAGAACCATTTGATGCTCCATCAACGTCAGCATCTAGAGACCAAGCCCAATATCAGCCAGCAGACTCAAAGTCAGAGTGCACAAGAGAATCAAGACAATACATTATCTGCtcagcagcaagctcagcagaatcagcaagcggcgcaacagcaaacgcaggctcagcaggcgcagcaacagtcgcagcagcagtcacaacttagtcaacagcaggcgcaacagcagtcacaacagcagtcacagcaggcCATGACTAGGGAACTGGTTATCAATTCGCAACCCGTGCAGGTGCAGGTGTTGCAGGGCAATGCACCTCAAATTATCAAATACGAAATAATGTCACATGAGCCGGGTCAAGCAATTGAGTGA
Protein Sequence
MCAAQSNPPATFGYTWGFADNTRTESVVEISPNINYTVSETMPYLQLTDSGGITVQKDSKGAIAHTNKGVVRRMIVMNEPFPQTTTQRVITTGSGATTVTHHKKHDVLTNGIIDTKAQTVLTTASGKMHFMSPIGPLQLTAEECNEILAKRAMSAAQTQHTTIATTTDGHHAGWSGIAVQVQKVIQGLEENDDSQTASSTHCKLEPVMSISPKLEFIEQPSSHEEAIPKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHVCVHCGKSFAHKHCLNTHLLLHSTDRPYQCNECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCDDCGESFAQKEHLVMHSRFHGSLNPFVCQDCGATFPRKFQLVNHGRIHGRVPHSCPICGKEFLQKRTLVAHTRLHTGDQPYPCTICGEGFRTKPELNQHNRQVHGGQSTTTTATANTIVATNAIVANNQHAQHVQVHTSQQQQPQQQTHQAQAAAQQQQQQQQQQQQQQQQQQQQQQQQTVTVVTNTNNGLVTTIATPSTAAEAARPQFACRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAAIPGHFLNTNINSGTTVVAANPAVVSPTPVPVQIITSSGQVVSQAMAVQSAPQPQQTVVQTVAPQQKPKTHFCSSCGKGFAAKHGLLQHNRRHTNGSCTLRTHVCECGKAFFQKNHLMLHQRQHLETKPNISQQTQSQSAQENQDNTLSAQQQAQQNQQAAQQQTQAQQAQQQSQQQSQLSQQQAQQQSQQQSQQAMTRELVINSQPVQVQVLQGNAPQIIKYEIMSHEPGQAIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01191418;
90% Identity
-
80% Identity
-