Ppap002008.1
Basic Information
- Insect
- Phlebotomus papatasi
- Gene Symbol
- ZFX_2
- Assembly
- GCA_000262795.1
- Location
- Scaffold79:154509-164004[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.6e-05 0.001 18.7 2.9 1 23 148 170 148 170 0.99 2 14 0.001 0.04 13.7 0.9 1 23 179 202 179 202 0.96 3 14 0.045 1.8 8.5 0.6 1 23 382 404 382 404 0.95 4 14 0.052 2 8.4 0.2 1 23 411 434 411 434 0.90 5 14 6e-05 0.0023 17.6 2.3 1 23 467 490 467 490 0.97 6 14 0.18 6.8 6.7 0.1 2 23 496 518 495 518 0.89 7 14 0.21 8 6.5 2.6 3 23 526 546 524 546 0.98 8 14 0.00017 0.0068 16.1 3.9 2 23 553 574 552 574 0.95 9 14 4.5e-08 1.7e-06 27.4 1.2 2 23 585 606 585 606 0.98 10 14 2.9e-07 1.1e-05 24.9 0.6 1 23 612 634 612 634 0.98 11 14 6.5e-07 2.5e-05 23.8 0.6 1 23 640 662 640 662 0.98 12 14 0.013 0.51 10.2 3.1 1 23 668 690 668 690 0.98 13 14 0.0015 0.059 13.2 6.3 1 23 697 719 697 719 0.99 14 14 7.3e-05 0.0028 17.3 1.1 1 23 726 748 726 748 0.98
Sequence Information
- Coding Sequence
- ATGCCCAGGAAGAAGTATAATCCAGTGGTTAATCTTGCTAAAGGGGAAGATGACTATGAGAAGCAGAAAACGAAAGGTGCATCTGGTGGGGAGACAGATGATGATAAGGACGAACCACTGTGGATGCAGACCCGAAACCGGAAGCAATATAGACAGTTTTCTAGTGATGAGGATAAGCCCCTGGTTGAGAGAAAAAGCACGAGGGGTAATAGAAAAGCCAAGTATTCCATGAAGAAATTGATGGGAGATGATCAGGAGGATATTCCGGAACCCCTCATTCCGGAGGAAAAGGTTGAGAAACGGGAAGAATCCTCATCATCAGATGATGAGTTTGAGCTGGTTAATATCGATGAAATAATTGTTCGGGATCCACCAGCTGACACCGAAGCTGAAGGGATTCCCGATTCCTGCACCGTTAGGGATAGGCATGGTAAGAAGGAGTACAAGTGTAGTAAATGTCCCAAGGTCTACTTGCGACCCAGCAAACTCAGGAAGCACTACCGGAAGCATACTGGCGAGACCAGGGCAAAATGGTACAATTGTTCAATCTGTTCCAAGCAATTCTCCACAGCCCTTAAACTGGACAAACACGTTATCCGTCGGCATAAAGAGGAAAATAACAGTGCTGGAACGTCCAGAGATGGACCAGTCAATCCTTTGGAAGTTCTCATTAAGGAGGAACCACCCTTCTACACGGATGATCCTGACATGGAGATCAAGCAAGAATTGGATGATGGCTACGAGGCCTACCTCCAGCCAAAAACCGAACTCATCGAATACACTCCACCTCGACCAGATTCCTCTCAATCCTCAGATTACTACCCCGATAACAATCCCGACATGCCAGATTCACCTGAACCTGATGTCTTGGATGTCAGTCAGCCCACTGAAGAGCCTCCGCAAGCTCCGGAGAAGTCTTCAGTGGCagaagaaaacaacgaaaagaaggcgaagaaaaggacgacgaagaaggccaaggaaaaggaagaagatgaagaagagggtgaaccgaagaagaagagaacaagaaagacaccggcaaaaccaaaagaacccagaaagccaagaCAGCGGAAGCCACCAAAACCGCCCAAGGAAAAGAAGAAGAAGCTCTCCCGGATGGAATTGTGGCGTCTTCGGCCTCACAAATGTCCCTTCTGTATTCGTCGGTATGCGGCCAAGGAGAACTTGGAAGCCCATCTGGAGTTCCATACGCGAAAGGAGAAGCACTTTCCCTGTGATAAGTGCGAGATGTCCTTTGATACCTTTGGCGCTCTACGCTTTCACATTGGGAAGGTTCATGTGGACAGGAATTGCAAAGTTTGCGGAGAATTGATGGCCACTCTAACTGACCAGTTGCGTCATAAGACAATGCATCTGGATAAGGAAATATATAAGTACGAGTGCGACATATGCCACAAGCGCTTTGCTCGTATCACATCCCTCAAACTGCACAAGAATAAAATTCACTCTGGTGGACCTCTTAAATGTCTCTCGTGTCCGCTAAGTTTCACGAAGCCTGTCTACCTTCTCGGACATGCCCTTGAAAAGCATAATGACGATAAGCCATTTGGCTGTAGCATCTGCAAATACCGAAGCAATCGACAGTACCATGTCGACATCCACTTTAGATCGCATTCGCTCGACTTGCAGTTGCATTGCGATATTTGTGGGCGGTTCTTTACCAATATGAGTAACTTCAATACGCATAAGAAGCAACATGAGGAAAATCCGGCTGACGTAGATTACAGGACGTGCAAGGAGTGTGGCAAAGTCTTTGCCAGAAGGACGTATCTCAATAAGCACATGAGAATCCATACGGGAGAGTTACCGTTTCAGTGCGCAGACTGTGAGAAGAGATTCACGACCAAGGGGCAATTGAAGGCCCACATGGTGAGTCATTCCAATATTAGGCCGTATCAATGTGAAATTTGCGCCAAGACATTCCCTCGGTCTGGAACGCTGAAGATTCATATGCGTTTCCACACGAATGAACGCCCATATCAGTGCAGGGTGTGTTCCAAAGCTTTTCATTCGGCCACTCTGAGGACAACCCATGAAAAGACCCATTCTGGAGAGACCAGAAAGTACACGTGCAACTACTGCAATAGGATCTATGTGAGTCATAGGTGCTTTAAGGCTCACATTAAGATGCATCAGAGCAATGCTGTTACCTTCCCTTGTCCCACTTGTGGGATTTGCTTCATAAAAATGACTCGACTCAATAAGCACATCTTGACGCATGTAAAGGAAATTCAGGAAATGCAGGAAGTACCAGAAGAACATAGCCCAATAGTTGTTCAATAA
- Protein Sequence
- MPRKKYNPVVNLAKGEDDYEKQKTKGASGGETDDDKDEPLWMQTRNRKQYRQFSSDEDKPLVERKSTRGNRKAKYSMKKLMGDDQEDIPEPLIPEEKVEKREESSSSDDEFELVNIDEIIVRDPPADTEAEGIPDSCTVRDRHGKKEYKCSKCPKVYLRPSKLRKHYRKHTGETRAKWYNCSICSKQFSTALKLDKHVIRRHKEENNSAGTSRDGPVNPLEVLIKEEPPFYTDDPDMEIKQELDDGYEAYLQPKTELIEYTPPRPDSSQSSDYYPDNNPDMPDSPEPDVLDVSQPTEEPPQAPEKSSVAEENNEKKAKKRTTKKAKEKEEDEEEGEPKKKRTRKTPAKPKEPRKPRQRKPPKPPKEKKKKLSRMELWRLRPHKCPFCIRRYAAKENLEAHLEFHTRKEKHFPCDKCEMSFDTFGALRFHIGKVHVDRNCKVCGELMATLTDQLRHKTMHLDKEIYKYECDICHKRFARITSLKLHKNKIHSGGPLKCLSCPLSFTKPVYLLGHALEKHNDDKPFGCSICKYRSNRQYHVDIHFRSHSLDLQLHCDICGRFFTNMSNFNTHKKQHEENPADVDYRTCKECGKVFARRTYLNKHMRIHTGELPFQCADCEKRFTTKGQLKAHMVSHSNIRPYQCEICAKTFPRSGTLKIHMRFHTNERPYQCRVCSKAFHSATLRTTHEKTHSGETRKYTCNYCNRIYVSHRCFKAHIKMHQSNAVTFPCPTCGICFIKMTRLNKHILTHVKEIQEMQEVPEEHSPIVVQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -