Parg001404.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- LSM2
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000041.1:1537146-1539492[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 3.2e-05 0.0013 18.6 0.6 3 23 253 274 251 274 0.96 2 9 1.1e-05 0.00043 20.1 1.3 1 23 306 329 306 329 0.91 3 9 0.0016 0.063 13.3 3.3 1 23 337 359 337 359 0.96 4 9 6.3e-06 0.00024 20.9 0.2 1 23 365 388 365 388 0.94 5 9 0.00017 0.0067 16.3 4.6 1 23 394 416 394 416 0.98 6 9 0.00024 0.0095 15.9 0.6 2 23 425 445 424 445 0.96 7 9 0.00012 0.0047 16.8 2.7 1 23 452 475 452 475 0.97 8 9 3.7e-06 0.00014 21.6 0.4 1 23 481 503 481 503 0.99 9 9 0.012 0.46 10.5 1.3 1 21 510 530 510 531 0.95
Sequence Information
- Coding Sequence
- ATGCAGGATTCGCAAAGCCTGAACTTCGAGATCTCAGTGAAGGAAGAGATCATCTCAAAGAGTGACGAAGTGTGTCGCTTCTGTGTTGGCAAGACTCCGGATTATTCCTCAATTTTCCAGGATGATCTTCACGAATCCCTGAAATCTTGCTTTGGATTGATGATTCAGGAGACAGACAACTGGCCAAAGTTCATCTGCCGGCAATGCCTGAACTCGGCGAAGACTTGCATAGACTTCGTGTCGAGAATCCGCGAAAGCGAGAAGAACCTCAGAGATCTTTACGGAGAATGGACAACTTGGAAAGATATTGAGAGGATTGAAATAAAGCCAGACATCGAGATGGTGGATGTCAAAGAACTCCCCTTACTTTGTGCTGACGTGAAAGCTGAAGTTGATCAACTGGAGGAATCAACAACAACCCGGAAGAAACCTCAGAAAAAGACAGTTCTCGAGGAGACTTTGCCCAGAAAAAGAGGACGACCCAGAAAACATCCTGTGCAATATGAAGATATTCCAGTATCCTGTGGTGATGATAAAAAAATGCTAGGAAAACTGGCTGGAAGACGGGGACGTCCGAAAATCTCATCTTGTTCTGAGGATGAAAAGCCATCAAGTCCCCCTCTAGAAGCTGCACATGACACCATGAAGGAAGAGCAGGAGGCCAAGGAAGAAGATAAGAATTTATCAGAATCTCAAAGCTATAAGGAATTATCGGACGAGAAATCCAGGAAAATTGAAGAGTTTTTTAAGATGGACTGCAATCAATGCCCTGAAAAGTTCTCTAGATTCAAGGATCTTCAGGCCCACTATCGATCTGTACACAAGAGAAAAGGATATATTTTGTGCTGCAAAGTGAAGTTGAGTCGAACGGCTAGAATTCTTCAGCACATTGAATTCCACATGAACCCGAACGTCTTCAAGTGTGACGAATGCGGGAAGACTTTCAAGAACAAGCTGGGCTTGCAGCAGCACAAGGTGAACAGTCACACCCCGAAGGAGCTGCACTTATACAAGTGTCCAAAATGCCCGAGGACTTTTATGCATCAGCAGCGCTTCAGGACGCATTCTGCTGTTCATGCAGAGCAGAGGAACCACATTTGTCCGGAATGTGGCAAAGCATTTCCCACAAAAGGCAGACTTAAGGCTCATGTTATGAATATGCACCAAGAAGTGTCCTATCACGTCTGCGAAATTTGCGCCAAGATGTTTAAGAGTAAGGACTGCTTCCTTGATCACCAACGAACACACACTGGAGAGAAGATTGAGAAGGTTCCTTGTCCAACTTGTGGCAAATTCTTCAGCGAGAAGCGGTTGAAAGTTCACATGAAGCGCCACAATGAGTCTGACGAGGTGTTCCGGTGTCACCTCTGCGACAGGGAATCAAACAGTCAGACATCCCTGAATCGGCATATAAAATATGTTCACATGAGCGAAAGAAAGTACAAGTGTAATCTTTGCGAGAGTTCCTTCAAAAGGCCAGTTGATCTCCGTGAACACATGGCGACTCACACTTCCAACCAGATCCTCTACACTTGCCTCTTCTGCCCAAAGCAGTTTAACAGCAATGCCAACAAGTATAATCATCAGAAGTTGTTTTACTCATTCTTCAAGTCACTCGTTGGGAAGGACGTGGTGGTGGAGCTGAAAAACGATTTATGCATCTGCGGGACTCTGCACTCCGTGGACCAGTACCTCAACATCAAGCTCACCGACATTAGCGTGACGGACCCAGACAAATATCCGCACATGCTCTCCGTGAAAAACTGCTTCATCCGAGGCTCAGTTGTGCGATACGTTCAACTGCCCAGCGACGAAGTAGACACACAACTACTTCAGGACGCCGCCCGGAAGGAAGCGGTGGTCAGCACGAGGTAG
- Protein Sequence
- MQDSQSLNFEISVKEEIISKSDEVCRFCVGKTPDYSSIFQDDLHESLKSCFGLMIQETDNWPKFICRQCLNSAKTCIDFVSRIRESEKNLRDLYGEWTTWKDIERIEIKPDIEMVDVKELPLLCADVKAEVDQLEESTTTRKKPQKKTVLEETLPRKRGRPRKHPVQYEDIPVSCGDDKKMLGKLAGRRGRPKISSCSEDEKPSSPPLEAAHDTMKEEQEAKEEDKNLSESQSYKELSDEKSRKIEEFFKMDCNQCPEKFSRFKDLQAHYRSVHKRKGYILCCKVKLSRTARILQHIEFHMNPNVFKCDECGKTFKNKLGLQQHKVNSHTPKELHLYKCPKCPRTFMHQQRFRTHSAVHAEQRNHICPECGKAFPTKGRLKAHVMNMHQEVSYHVCEICAKMFKSKDCFLDHQRTHTGEKIEKVPCPTCGKFFSEKRLKVHMKRHNESDEVFRCHLCDRESNSQTSLNRHIKYVHMSERKYKCNLCESSFKRPVDLREHMATHTSNQILYTCLFCPKQFNSNANKYNHQKLFYSFFKSLVGKDVVVELKNDLCICGTLHSVDQYLNIKLTDISVTDPDKYPHMLSVKNCFIRGSVVRYVQLPSDEVDTQLLQDAARKEAVVSTR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -