Basic Information

Insect: Phlebotomus argentipes
Gene Symbol: -
Assembly: GCA_947086385.1
Location: CAMTYR010000037.1:3697081-3699391[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.013 0.49 10.5 0.4 2 23 228 252 227 252 0.95

2 14 0.012 0.45 10.6 0.0 6 23 262 279 262 279 0.96

3 14 0.0005 0.019 14.9 3.2 1 23 285 307 285 307 0.98

4 14 0.0048 0.19 11.8 0.5 2 23 316 337 315 337 0.95

5 14 4.9 1.9e+02 2.3 0.1 2 20 425 445 424 450 0.84

6 14 0.032 1.3 9.2 0.4 6 23 459 476 459 476 0.96

7 14 0.0057 0.22 11.5 1.5 1 23 482 504 482 504 0.97

8 14 0.00011 0.0041 17.0 0.1 2 23 513 534 512 534 0.95

9 14 1.5e-05 0.00057 19.7 1.0 1 23 542 564 542 564 0.98

10 14 3e-05 0.0012 18.7 2.4 1 23 570 592 570 593 0.96

11 14 0.00022 0.0086 16.0 0.1 2 23 600 621 599 621 0.96

12 14 9.2e-05 0.0036 17.2 0.9 1 23 627 650 627 650 0.96

13 14 0.061 2.4 8.3 5.7 1 23 656 678 656 678 0.97

14 14 0.011 0.45 10.6 4.4 1 23 684 707 684 707 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.013	0.49	10.5	0.4	2	23	228	252	227	252	0.95
2	14	0.012	0.45	10.6	0.0	6	23	262	279	262	279	0.96
3	14	0.0005	0.019	14.9	3.2	1	23	285	307	285	307	0.98
4	14	0.0048	0.19	11.8	0.5	2	23	316	337	315	337	0.95
5	14	4.9	1.9e+02	2.3	0.1	2	20	425	445	424	450	0.84
6	14	0.032	1.3	9.2	0.4	6	23	459	476	459	476	0.96
7	14	0.0057	0.22	11.5	1.5	1	23	482	504	482	504	0.97
8	14	0.00011	0.0041	17.0	0.1	2	23	513	534	512	534	0.95
9	14	1.5e-05	0.00057	19.7	1.0	1	23	542	564	542	564	0.98
10	14	3e-05	0.0012	18.7	2.4	1	23	570	592	570	593	0.96
11	14	0.00022	0.0086	16.0	0.1	2	23	600	621	599	621	0.96
12	14	9.2e-05	0.0036	17.2	0.9	1	23	627	650	627	650	0.96
13	14	0.061	2.4	8.3	5.7	1	23	656	678	656	678	0.97
14	14	0.011	0.45	10.6	4.4	1	23	684	707	684	707	0.97

Sequence Information

Coding Sequence: ATGCTGAAGAGAGTGTGGGGAAACACTTGCCGGATGTGTCTGGAGAACAAGATCCAGTGCATCGACACAGATGTTCCGGGAACGTTTAAGGATTATGTGTCAACAATATTGTTAGAGATTTTCCAAATTACAATTGTTCCTGAGGAGAATCTGCCGCAAGAGGTGTGCTTTGACTGCTTCGCAAAGTCCAACTCTCTGTGGCAATTCCGGCAGCAAGTGATTGAGAATCAACAGTTGTTGCTTCAGCAGGTCCCGGAAAGTGCTGTTGTTGCCATAGAGGAGTCAGATTATGTGGAGTCAGAGGAGTATCCGGGCGAGGAGGAGCTTGATGATGGTGTGTTGAAGGAGGAATATGGGATTGACGAGGAGACTGCAATTGAGGAGGATATTATTGTCGAGGAGCCTTGGGAAGAGGATTACAGCTTGGCAGAGGAATCTGCCATTCAGGCGGATGTTATGGAGCTGATTGAAGAGTCTGCAGATGAGGCGCCGCCAGTGCAGGAGGAGTTGATTGAGAAGCCGACGGAGGAACAGCAATCAAAGAAGCGAAAGTGGGAGAAAAATCCAAATGTTGACAGTGTTCTTCTCGAGCACTTTCCCCAATTGGCCACTGTCGTCTGTCCGCTGGACAACATGAGTTGGTCAGAGAAGGATGAACTGCTGAGGGAATTTGTGAAGCTGAAGTGCAGAGATTGCGACAGTGCGCAAGCATTTTCCACCTTCGACGACTTGCAGGATCACTACAGACTGAAGCACAGAGAGAAGCGCTGCATCGTGGAGTGCTGTGGGAAGGATTTCTCTCGCAGGGATCTGCTGTACGCTCATGTGGTGGTTCACAAGTATCCCGATGCGTTCTCCTGCTTCGTGTGCAAGCGTCAATTCAAGGGCAAGGAGCTGTTGAAGAAGCATCTCTTCACGCATCTGCCGTACGAACTGCGGCCGCTGCAGTGTGAGAAGTGTGACAAGAAGTTCCTGGCCAACAATCAGCTGCGCCTGCACATGCTGGGCCACACGCAGGAGCGACGCAAGTCACCGGCGAAACGGCGCAGCTTCCCGGGCATCACCTGGGCGGAGGGCGAGGAGACCGTGGAGGAGGAAGTGATGGACGATGGCACGGAGATGTACAAGAGTATCATTGACAACAAGATGAGAATGTACGACAAAGATCGCGCAATCTACGAACACTTCCCCGACTTTGACTACATCGGCTCCACATCAGCGTCCGTGCCGCTGGAGGAGCGAGATGAGGTGATAAGGCGCTTCGTGACGCTTCAGTGTCAAGAGTGCGACGCCCGGCCGACTTTTCCCACCTTCGAGATGCTTCAGGATCACTACGCCGAGCAGAATCACACCAATCAACCGTTCGTGGTGTGTTGCAACAAGAACTACTATCGCAAGGTGAATCTCATCAACCACATCACCTTCCACGTGAATCCCAACGTGTTCGCGTGTCCCGTGTGCGCGCATCAGTCGAAGAGCAAGGAGCTGCTGAAGAAGCACCTGTACACGCACCTGCCCAAGGCCGTGCGGCCGCTGGAGTGCGCTCAGTGTGGCAAGAAGTACGTGACGAAGGCGCAACTGCGACTCCACGTCGCCAGTCACGTGCGGAAGGAGGACAGATCGCACGAGTGTCCGGAGTGTGGCAAGAAGTTCGCCTACGACTTCGCCCTGGAAACCCATCGACGATCACACAGACGCGTGCCGGATTATGTGTGTGAGATCTGCGCCAAGACATTCACGGGAAAGAGCAACTATCAGGACCACAAGATGCGCCACCACGAAATCCCCGAGCCTGTTGTGTGTCCGATTTGTGAGAACACGTACAAGAACAAGATCAGCCTGCGAAGTCACATGGCATTGCACACGGATCTCCGCGAGCACAAATGTGAACAGTGCCAGAAAACCTTCACGGCCAGAGCTGGTCTTCTGGCGCACATTCGCTTCGTGCATTCGGAGCAGTTTCTCTACCACTGCAACATTTGCAAGAAGAAGCTGCGCACCAAATCGGATCACAAGGATCACATGGCAAATCATCTCGGCCAGCCGATGTATCACTGTGAATTCTGTCTCAAGTCCTTCACGGCGCGCTCATATTACTTCGCACACAGGAAGAAGGCGCATCCCGAGGAGCACGCGAAGCTGCCCAAGAAGCAGAAGTTTCACGTGGAGAACTGA
Protein Sequence: MLKRVWGNTCRMCLENKIQCIDTDVPGTFKDYVSTILLEIFQITIVPEENLPQEVCFDCFAKSNSLWQFRQQVIENQQLLLQQVPESAVVAIEESDYVESEEYPGEEELDDGVLKEEYGIDEETAIEEDIIVEEPWEEDYSLAEESAIQADVMELIEESADEAPPVQEELIEKPTEEQQSKKRKWEKNPNVDSVLLEHFPQLATVVCPLDNMSWSEKDELLREFVKLKCRDCDSAQAFSTFDDLQDHYRLKHREKRCIVECCGKDFSRRDLLYAHVVVHKYPDAFSCFVCKRQFKGKELLKKHLFTHLPYELRPLQCEKCDKKFLANNQLRLHMLGHTQERRKSPAKRRSFPGITWAEGEETVEEEVMDDGTEMYKSIIDNKMRMYDKDRAIYEHFPDFDYIGSTSASVPLEERDEVIRRFVTLQCQECDARPTFPTFEMLQDHYAEQNHTNQPFVVCCNKNYYRKVNLINHITFHVNPNVFACPVCAHQSKSKELLKKHLYTHLPKAVRPLECAQCGKKYVTKAQLRLHVASHVRKEDRSHECPECGKKFAYDFALETHRRSHRRVPDYVCEICAKTFTGKSNYQDHKMRHHEIPEPVVCPICENTYKNKISLRSHMALHTDLREHKCEQCQKTFTARAGLLAHIRFVHSEQFLYHCNICKKKLRTKSDHKDHMANHLGQPMYHCEFCLKSFTARSYYFAHRKKAHPEEHAKLPKKQKFHVEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -