Parg002207.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- -
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000041.1:9204826-9206310[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0022 0.086 12.8 2.5 1 23 175 197 175 197 0.97 2 9 1.5e-05 0.00057 19.7 1.3 2 23 204 225 204 225 0.97 3 9 4.4e-05 0.0017 18.2 1.6 1 23 231 253 231 253 0.98 4 9 3.2e-07 1.3e-05 24.9 0.5 1 23 259 281 259 281 0.98 5 9 4.2e-06 0.00016 21.4 2.0 1 23 287 309 287 309 0.97 6 9 3.6e-07 1.4e-05 24.8 2.2 1 23 315 337 315 337 0.98 7 9 1.4e-05 0.00054 19.8 5.8 1 21 343 363 343 365 0.96 8 9 0.00031 0.012 15.5 1.5 1 23 371 393 371 393 0.98 9 9 1.7e-07 6.6e-06 25.8 1.3 1 23 399 421 399 421 0.99
Sequence Information
- Coding Sequence
- ATGGATAAATTGGTAAAGAACAGCTTGAATAATCTCTGCCGAGGGTGTCTGCTGAATTTAGACACAGCTGACAGTGTTGTTTTCGCTTTGTGTGACGAATCAAGTAGTTCAGAGAAGTTTGAATGCTGCACTAATATAAAAATCTGTGCGAGCGATGGCTTGCCGACAAATTTGTGCATGGAGTGCATGGACAAGTGCAATTCATGGTACGACTTCAAGAAACAATGCGAAGAGTCGAACGAGATCCTGCAGAAACTTATCCACCAGCGGGAAGCGACAGAGGCTCCTCTTGAACACCTCGAGAATGCTAGCGCTTTGGTCTTCACCTTTTCCGGCAGCTCAGCAGAAATGCACGAACTGGACAGCGTGATTCTCTCTGAAATTGACTTGGGCATAAAAAAAGACATCGCAGAGGATTCTCAAGTTGCTCTGGTTGGTGAAAACTCACCGGACAATTCTAGCAACGAGGCGGACATTGAGGAGCCCAGGAGCGCAAGGAAAACGAAATCTGCCCGCAGTCAGCATCGATGTGCGAGCTGCAAGAGGAATTTCAGGAACGAGGAACGCTACGAAGCTCACATGAGAGAACACAAAGGGCTCAAGCCAGAAGTGTGTAAGATCTGCAACAAGGAGTTTAACAACTTGAGAGCACTTCGGCGGCATCGAATAAAGCACAACGACATGAAGCAGTACTCTTGCCAGACGTGTGGGAAACAGTACAAATACGCCACATCGCTCACtctccacacgaaggtgcacaagaacatccggtgctacatctgtgatctctgcggcaaatctttcatccgcgcccacggtctgcagagtcacatgctatcgcactccacggagaagcccttttcttgcagcacctgcgacaagacctttaagaaccaggtgatgctgaagaaccacgaacttcgccataacggtgtgaagagattcatctgctcagtgtgcgggaagtgcttcaccacgtcgcctgaactgactacgcacacgaggagtcatacgggaatcaagccgttcaagtgcacgatgtgcgagaagagctacaagaccaagagccatttggctgttcacatgagatgccacacaggactgagaccgtatgcctgtgatctgtgtccgcagaagttcgcccacaacaaggtgctgaagcaacacagattgacgcacacgggagagcgtccgtatagctgtgatgtgtgccagagacccttccggcagaagagcaccctcaaggcccacctgaagactcaCAAGCAAGTTGAGCAGTCGCCTACAATGGACCAATTCTCCGTGGCTTCTTACCTTGGCGATGGCCAGACCATAGAGATGTCACAAAGCGATTATATATCCATGTAG
- Protein Sequence
- MDKLVKNSLNNLCRGCLLNLDTADSVVFALCDESSSSEKFECCTNIKICASDGLPTNLCMECMDKCNSWYDFKKQCEESNEILQKLIHQREATEAPLEHLENASALVFTFSGSSAEMHELDSVILSEIDLGIKKDIAEDSQVALVGENSPDNSSNEADIEEPRSARKTKSARSQHRCASCKRNFRNEERYEAHMREHKGLKPEVCKICNKEFNNLRALRRHRIKHNDMKQYSCQTCGKQYKYATSLTLHTKVHKNIRCYICDLCGKSFIRAHGLQSHMLSHSTEKPFSCSTCDKTFKNQVMLKNHELRHNGVKRFICSVCGKCFTTSPELTTHTRSHTGIKPFKCTMCEKSYKTKSHLAVHMRCHTGLRPYACDLCPQKFAHNKVLKQHRLTHTGERPYSCDVCQRPFRQKSTLKAHLKTHKQVEQSPTMDQFSVASYLGDGQTIEMSQSDYISM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -