Parg008921.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- -
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000037.1:15837981-15841495[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 3.5e-05 0.0014 18.5 0.7 1 23 162 184 162 184 0.95 2 15 0.055 2.1 8.5 5.4 1 23 190 212 190 212 0.97 3 15 2.3e-05 0.00088 19.1 0.3 1 23 319 341 319 341 0.98 4 15 0.0025 0.096 12.7 0.1 1 23 347 369 347 369 0.99 5 15 0.00062 0.024 14.6 5.2 1 23 402 424 402 424 0.97 6 15 0.0056 0.22 11.6 0.2 1 23 437 459 437 459 0.94 7 15 0.094 3.7 7.7 0.3 1 23 465 488 465 488 0.95 8 15 0.0033 0.13 12.3 1.7 1 19 495 513 495 514 0.96 9 15 0.0012 0.047 13.7 6.5 1 23 523 545 523 545 0.97 10 15 0.002 0.079 13.0 0.6 2 23 551 572 550 572 0.97 11 15 1.1e-05 0.00044 20.0 0.4 1 23 580 602 580 602 0.98 12 15 0.0003 0.012 15.6 0.2 3 23 610 630 608 630 0.97 13 15 5.9e-05 0.0023 17.8 0.5 1 23 636 658 636 659 0.95 14 15 0.0025 0.096 12.7 0.0 1 23 673 695 673 695 0.97 15 15 0.0018 0.071 13.1 0.6 1 23 1082 1104 1082 1104 0.97
Sequence Information
- Coding Sequence
- ATGGATGAGGAGGAAACCTACCAGATCGAGTGGATTCAGAGCGATGGGGACGACGGGGAGGTCCTGGATGATGGTGACATAATCCAGGAGGTACCCGAGGATGACGGTGTGGATATGGATCCGGGAACACTCAATGAAGATGACATAATTGAAGAAGTGGACGACGATGAGTACATTGCTGCGATGTCGGATCATCTTCAGCATGATTCCGCCGGGAATCTCGTGTACATGTCACAGGACGGATCGAGCATGGGCAACATCATTGAGGAGCACGTGCAGGAGGCCGAAGTGGAGGAGTACACAGAGCAGCAGCAGTTTGATGGGCAGGTGTGCGAGGAAGTTGTCATTGACGAGAGCGGCGTGCCGGACGACAAGATGGAGATTCTGATTGACAACAACGGAAGTGTCGTCCAGGACGGTGGGCAAGTGGACGAGGAAATTGTACCGCTGCCGCCGCAAGATGAATACACAACATCACGGCCGTATCCGTGTGACTTCTGCAGTCGCCGCTTTAGGAAGAAAGCCAACCTCATGAATCACATGGTGGCCCATCAGACGGACAGGCCTCATGTGTGCAACCTCTGTGGCGCTCGGTACATCCGCCGCTGTGACCTGCACAATCACTTCAAGATCCACGCTTACGCACCAACAGACCACGATCTCGGTGGCACAGAGTTCCTCGCCGGTCACAACGACGAGGAGGAAGATGACGAGGAGCAGGACAAGAAGCCCTTCGTGGAGTACTCCACAATGTCGGTGAGTCCGCGGAAGAAGGTGCAACAGGCATCGCCGCGTAAGAGGACGCTGAAGGTGGGCAACAATGCTCGTGAAATGCCCAAATACGACTATGTGGATGAGGACATGAAGCTGGTGTGTGACTCAACACAGCCGGCTCAGCATGAGGAGATTTATCCGATGGTTGAGCAATTTCCAGTAACGGATCCAAAGAAACCATTTGTTTGTCAACACTGTGGAGTGTCCTTTGCCCGTGAGAAGGCTTTGGCCTCACACGCTAGGATGCACGGCGGGGATTCACCCTACGAATGCGAGACATGCGGCGAGATGTTTTGGGATCCAATTCGCTTGCGAGAGCATCAGATGACGCACAGAATGGATCAAGGTAGCACTTCTGAGTATGATGTTGTGGCGAATGACGAGGAGACAGAGTCAGATTCCGGCGAGGGTGAGGAGAAGTTTGGGGATTTCTACTGTGACGTGTGCGGAATGTGTTTCCATCGTCATGCCCTGCTGAAGCGCCACGCAAGGGCACATGTGAAGAAGGAATTGGTGGATAATGACATCTCCAGGCACTGCTGCAATGTGTGTGGAGAGACTTTTGCAGAGGCGCTGGATTTGTTGGCTCATGCTGAAGTGCACGCACGCTTTCAGCCCTTCAAGTGTATGCTTTGTGGCGAGACATTCCTGGATGAGACGACCATCAAGGAGCACATTGACACGACTCACGCTGACGAGTTgacaatacactcgtgccgattgtgtggcaaggtgtgtcgtgacagtcgatcactgatgaagcacgcgtgggatcactccagggagaagacacattcctgctccaaatgtgccaagacgtttcacaacaaggcgcgcttgaagcgccacatgatgtcgcatcgcaacaagtccgtcacgtgtgacgtgtgtggcgagaagttcccggatggtcggagtctcatgaaccaccgtcactcgcacacaaatgtgtcagggcgacagtttccgtgtcgggagtgcggcaagacgttcgggtcgcgcagctcgcagcagatccacattcgcatccacactggagagcgtccgtacggatgtaaatactgctggaaggcgtttgccgatggtgggactctgcggaagcacgagcgtattcacactggggagaagccgtacgcgtgttccgtgtgccccagggcgttcaatcagcgagtcgTCTTGcgggaacacattagatcacatcACTCAGCTCCGGATTCACAGCGCGGCACCACAATCACTCCATACTACTGCGAGGTGTGCTCTGAGATGTTCGCCCTGCCGACGGAGCTCATTCAGCATCTCATCCAGCACAGTGATATGAACACACTGGCCAAGAGACAGCCACCGACGGGTCCGCGGAAGTACAAACGACGCCGCAAGTTGAAACCCCATGAATTGGAACGACTTCGCGCGCAGCGCTCTAAGAACTCTGATGTGGATTTGTCAGAGGACGATCCCATGCAATCAGAGGTGGGAATGCAGGAGAGATATCAAGCGTCACCGGTGGTGGCACAGGGCAATTCTGCCGGCAATCGCCAAGGTGGAACACCTGCTCGTCGTTCAAGGAACACTTTCAATGTTGATTCATTGGAAGATCGTCAAATGCTGCGCTCGTCGGAAGACTTTGAGACGTCCGTGGCGAAATTCGACCTGAATAAGGGTGCGAATACGCGCAAGAGGAACCTCGTGGCCGCGTCTCTGTCCGCTGCGGCTGTAGCTATGCCAGGACAATCGCGTCCAAAGATGATTAGGACGCAGAAGACACGCGTTGCCGTGGAGGATGGCAAGAGGCGGACGCGCACACTCATCACACGCACAGCACCAACGGATTTGGGCTCTTCAGCTGGATCAGCGAATCAGGCAAATATGACTGCTCGTCAGAAACAGACGCGAGCAAGGATTAAGAATGTAAACTATCACTATCAGACTGATAGGATGATGAGTCCGGCGACATTCTCGGATGTGAATGAACAGATCACGCAGGATGTGATGAGTGTTAAGCAGGAGCCGGTGGAAATGACGGCAACGGCCACTGTTCTTGAGCATGACGGCAGTGGCTTGTCGAAGAGAACGTACAATAAGTACAGCATGGATATTGTCAACGATCTTGAGGCAATTCTCAGGTCTCCCATCAAACAGTCACCCTCTTCTGGGAGCCAGAGAGAGATGAATCAGGTGTCTCCGAGTGAGCCAAGTGCCAAGGGAGCGAGTGCTGCTGGTAGTAAGAGCAGAAGACAACTTTCGACTCCGGGAAAGAAGCGGCTGCAGGCTGAACTGACTGCCGTATCGGTGTTGCCCGTTTTCTCCAATGCCAACCTCACGAAGCGTCAGCTGGCTCTCGCGGCGAAGAAGAGCGCCAAGGGAACCAGTGACAAGGATGTGTTGCTGATAGCGAAGGAGGAGAAGGACAATGAAGTGATCACGGGCGATATTGATGATACGGGCGTGATGAAGAGCAACGCTAAGGAGTTCAAGTGCGAAATGTGTTCATCCATGTTCTTCACGCAGGATGATCTCTTCACTCACGTGGCAATTCACATTTAA
- Protein Sequence
- MDEEETYQIEWIQSDGDDGEVLDDGDIIQEVPEDDGVDMDPGTLNEDDIIEEVDDDEYIAAMSDHLQHDSAGNLVYMSQDGSSMGNIIEEHVQEAEVEEYTEQQQFDGQVCEEVVIDESGVPDDKMEILIDNNGSVVQDGGQVDEEIVPLPPQDEYTTSRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHVCNLCGARYIRRCDLHNHFKIHAYAPTDHDLGGTEFLAGHNDEEEDDEEQDKKPFVEYSTMSVSPRKKVQQASPRKRTLKVGNNAREMPKYDYVDEDMKLVCDSTQPAQHEEIYPMVEQFPVTDPKKPFVCQHCGVSFAREKALASHARMHGGDSPYECETCGEMFWDPIRLREHQMTHRMDQGSTSEYDVVANDEETESDSGEGEEKFGDFYCDVCGMCFHRHALLKRHARAHVKKELVDNDISRHCCNVCGETFAEALDLLAHAEVHARFQPFKCMLCGETFLDETTIKEHIDTTHADELTIHSCRLCGKVCRDSRSLMKHAWDHSREKTHSCSKCAKTFHNKARLKRHMMSHRNKSVTCDVCGEKFPDGRSLMNHRHSHTNVSGRQFPCRECGKTFGSRSSQQIHIRIHTGERPYGCKYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSAPDSQRGTTITPYYCEVCSEMFALPTELIQHLIQHSDMNTLAKRQPPTGPRKYKRRRKLKPHELERLRAQRSKNSDVDLSEDDPMQSEVGMQERYQASPVVAQGNSAGNRQGGTPARRSRNTFNVDSLEDRQMLRSSEDFETSVAKFDLNKGANTRKRNLVAASLSAAAVAMPGQSRPKMIRTQKTRVAVEDGKRRTRTLITRTAPTDLGSSAGSANQANMTARQKQTRARIKNVNYHYQTDRMMSPATFSDVNEQITQDVMSVKQEPVEMTATATVLEHDGSGLSKRTYNKYSMDIVNDLEAILRSPIKQSPSSGSQREMNQVSPSEPSAKGASAAGSKSRRQLSTPGKKRLQAELTAVSVLPVFSNANLTKRQLALAAKKSAKGTSDKDVLLIAKEEKDNEVITGDIDDTGVMKSNAKEFKCEMCSSMFFTQDDLFTHVAIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -