Parg010648.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- -
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000025.1:5931099-5932552[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00099 0.039 13.9 3.1 1 23 56 78 56 78 0.98 2 14 6.6e-07 2.6e-05 23.9 1.5 1 23 84 106 84 106 0.97 3 14 6.7e-05 0.0026 17.6 1.1 1 23 113 135 113 135 0.98 4 14 0.0009 0.035 14.1 2.5 1 23 141 163 141 163 0.93 5 14 0.00028 0.011 15.7 0.2 1 19 169 187 169 193 0.93 6 14 5e-06 0.0002 21.2 1.9 2 23 202 223 201 223 0.97 7 14 2.9e-07 1.1e-05 25.0 0.8 1 23 229 251 229 251 0.98 8 14 6e-05 0.0024 17.8 1.0 1 23 258 281 258 281 0.97 9 14 0.18 7.1 6.8 0.6 1 10 294 303 294 316 0.79 10 14 1.1e-05 0.00043 20.1 0.3 1 23 322 344 322 344 0.99 11 14 1e-05 0.0004 20.2 1.8 2 23 352 373 351 373 0.97 12 14 7.6 2.9e+02 1.7 5.3 3 23 379 401 377 401 0.89 13 14 6.3e-05 0.0025 17.7 0.5 2 23 412 433 411 433 0.97 14 14 0.0021 0.081 12.9 1.8 1 23 439 462 439 462 0.97
Sequence Information
- Coding Sequence
- ATGGAAAATGACGAAGACGTAAAAGAGGTGAAAGTAAAGTGTGAGAATGTAGAAAATGAGCAGGAATTCGATAAAATCGTGAAGGATGAAGAAAAGATATCCAGGAAACCGAGAAAACCCCGAAAGCAGGAGTTTGGAAAGCTTGGAAATGTGAAGGAGAATAAGTTCAAGTGCACAGAATGCGACAAATCCTTTGCGTGTCTCTCCAAAATCAAGACGCACATGTCTGTGCATGTGACAGAAAAGTCCTTCTTTTGCACACAATGTCCGAAAGCCTTTGCGGATCAAAGTCGATTGAAGACTCACATGAAAACCCACGTTGAGGGGAGGAAAACTTACCCTTGTCATCTGTGCGAGAAGACCTTGACGACACCGGAAAGTCAGAAGAGACACATTGAAACTCATTCCAAAAGCACAGAACATCGATGTGTTTCGTGTGATAAAGTCTTCAGCAGAGCCTGCGATCTCAACAGTCACAGTGTCATCCACTCCACGGAGAGACTCTTCAAGTGTCTGATCTGCGAGAAGGCCTTTCCCACAGCTCGACTCCTGAAGAACCACGGAACACTGGCGAATCATCACACGAGTGATAAGAAGACCGTTTCATGTCCACAATGCCAGAAGACCTTTGGCTCCAACACACACTTGGCCACACACATGCAGAAGCACTCCAAGGATTGGCACTTTCCCTGCCCACTGTGCGGGAAGAGGTTCAGGAAGCCAACATATCTGCGTATTCATCTCAAGAGACACAGCAGCGATCGCCACATGTTTGAGTGTGAGAAGTGCGACAAGAAGTACACGACAAATGCGCGTCTGATTGATCACGTGCAGCGGAAGCATCTGGGCATGAAGACACCCGAGATTGCCAAGAAGTCGTACACATGTGAGATCTGTGGCAAAGTCTCCTACACGGGATTCGTTCATCGGCAGCACGTGACGTCTCACAGTGGAATCAGGGAGTTTCAGTGTCCCATTTGCGCACGCATGCTGAGGACAAAGGCAAACCTCAAAGGTCACCTGAAGACACACAATAAGCCACAGAAGATCATTGAGTGTGGCATCTGCAAGAAGACCTTCAAGAGACAAACTAATATGGATTATCACATGAAGAAACACTTTCAGCCCACCATTTGCTGCATCCACTGCGGATTGGAGCGCAAGACTGAGTGCGATCTGAAGAAGCACACTGAACTCTTCCACAGAGGTCTTCCAATGTCTCCAAACAGCACAGTGTGCACAATTTGCCATGAGGTCTTTGAGAATCTGGAAACACTCAAGGAACACGTGAAAATCCATCCAGTTGAGCTACGCTTTGAGTGCGGTCACTGTGGAAAGAAGTTCCTGGACAAGCAGAGAATCAGACAACACATTCGCATCATGCATGACAAGTAG
- Protein Sequence
- MENDEDVKEVKVKCENVENEQEFDKIVKDEEKISRKPRKPRKQEFGKLGNVKENKFKCTECDKSFACLSKIKTHMSVHVTEKSFFCTQCPKAFADQSRLKTHMKTHVEGRKTYPCHLCEKTLTTPESQKRHIETHSKSTEHRCVSCDKVFSRACDLNSHSVIHSTERLFKCLICEKAFPTARLLKNHGTLANHHTSDKKTVSCPQCQKTFGSNTHLATHMQKHSKDWHFPCPLCGKRFRKPTYLRIHLKRHSSDRHMFECEKCDKKYTTNARLIDHVQRKHLGMKTPEIAKKSYTCEICGKVSYTGFVHRQHVTSHSGIREFQCPICARMLRTKANLKGHLKTHNKPQKIIECGICKKTFKRQTNMDYHMKKHFQPTICCIHCGLERKTECDLKKHTELFHRGLPMSPNSTVCTICHEVFENLETLKEHVKIHPVELRFECGHCGKKFLDKQRIRQHIRIMHDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -