Parg002384.2
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- ZNF629
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000041.1:10322519-10326154[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.00053 0.021 14.8 2.1 1 23 169 192 169 192 0.96 2 21 0.0006 0.023 14.6 1.4 1 23 199 221 199 221 0.95 3 21 0.00044 0.017 15.0 0.2 1 23 230 253 230 253 0.94 4 21 2e-07 7.9e-06 25.5 0.4 1 23 259 281 259 281 0.98 5 21 0.00041 0.016 15.2 5.6 2 23 288 309 287 309 0.95 6 21 0.0063 0.25 11.4 0.9 1 23 314 336 314 336 0.96 7 21 0.00028 0.011 15.6 2.6 1 23 342 364 342 364 0.97 8 21 0.0016 0.064 13.2 2.8 1 23 370 393 370 393 0.97 9 21 0.0033 0.13 12.3 1.1 2 23 543 565 542 565 0.96 10 21 0.0057 0.22 11.6 6.1 1 23 572 594 572 594 0.97 11 21 2.5e-05 0.00097 19.0 0.3 1 23 603 626 603 626 0.95 12 21 0.00069 0.027 14.4 0.6 1 23 632 654 632 654 0.95 13 21 0.47 18 5.5 4.6 2 23 659 681 659 681 0.95 14 21 0.00038 0.015 15.3 1.8 1 23 696 719 696 719 0.97 15 21 0.0023 0.09 12.8 1.8 1 23 726 748 726 748 0.96 16 21 0.11 4.2 7.5 2.1 1 23 757 780 757 780 0.92 17 21 7.6e-05 0.003 17.4 0.1 1 23 786 808 786 808 0.95 18 21 0.016 0.62 10.1 6.4 1 21 814 834 814 836 0.95 19 21 0.00027 0.01 15.7 0.3 2 23 842 863 841 863 0.95 20 21 0.0095 0.37 10.8 5.1 1 23 869 891 869 891 0.98 21 21 3.7e-06 0.00014 21.6 1.6 1 23 897 920 897 920 0.98
Sequence Information
- Coding Sequence
- ATGCTGGGAGAACTTCTGGAAATTGCCAATAAATACTTCACGGTTTCGTTGCCTGAGGAAAACTTGCTTATCTGCGATGATTGCTCAAATTTCCTGCTGAAGCTAGAGAACTTCGAAGAGCGTTGCCTGAAGGTGGATATAATGCTAAAGGAGATTAGTGAAGATCAAAATATGCAAGAATCTAATCTTCAGGCCATGCGCATAAAGTATGGTTTTGATGTGCCAGAAGAAAAATATCAGATTCAACTGTTAGAGATCCGGAAAGAAGAGGATGACTTCTCTGACGATGTGTACTCGGATCCTCTCGATCAGGATATTATAAAAACGAGGGAAACAGTTGTTGTGAAGATGGAAACCCCCGAAGAGGAAGATTCAGAGAGCCTCAAGAAGCGTGGTCGTCCTAAGAAATTAAGAGAGTCCATTAAGAGAAAACTGCAGGAACAAGAAGACATCGAGTCTCCGAAGAAGAGGAAAAGAATGTGGAAGGGAGACGGCGAGAAGAAGCACATTTGTTCCTATTGTTCGAAAGCTTTCAGCCGGCAAAACGTGATGAAGGATCACATCTTGACGAAGCACCGCAAGCAGGACATGATTCACGCTTGCTCGCAGTGCCCGAAGAGATTCGCCACCAGCTACAGATTACGACTCCACGAGGCCACACACTTGCCGGACGCCGAGAAACTCGTGCATCCTTGTCCGTTCtgcgacaagaaattcagccagaaagtcggcgccgaagtgcacatcaacgccatgcacttgggcgagaagtccttcacctgcgaagagtgcggaaagtctttcagcacgaaaggtgctctgacagagcataaaatcacccacacggatgagcgtccttgtcagtgctcattctgTCCGAAGAAGTTCAAGAATCAGCGGCAGCTGAAGCAACACGAAAGCAGTCACAAGGAATCTGGCCACGCTTGTCCGCACTGTGGCTTAAAGCTGAAGAGCATCGTGACTCTCAGGATGCATTTGTTGGTGCATTCGGACAAAAAGAAGTACAAGTGCAACTATTGCGGCAATGAATATAAGCGTTCAAAGACATTTAAGAGTCACTTGATTCTGCACACCGGCCAGCGCCCGTACGAGTGTCCTTTCTGTGATAAAACTTTTGCGAATGGATCTAATTGCCGGAGCCACAAGAAAAAAGCGCATCCAGCCGAGCTTGCGGCTTTAGAAGCTACAGGAAGTCAAGATACAGAGAATGCAGTTGAGAGAACCAGAAGCAAACTAGACATCGTCAACAAATATTTCATGATTTCTCTGCTTCCCTTCGCTGGGCCACAAACGTCGATTTGCGAAAGCTGCAGTGAATTTCTGTCCAGAGTTGATGCATTCAAGGATCTCTGTATGAAGACAGATGAGATGTTTAGAGAGTTGTTGTTGCAAGAGGAGACTTCAGAGGCATTTCTTACATCTATTCGCATCAAATTCGGCATTGATATTGAGATAAAGGACGACAAATTCAGTATTGACACCGAGATTAAGGAGGAAGAAGAGTCGGTTGATGATTTTGATCCTCTCTTCGATTGCAAAGTTGCGAGTGAAGTAGAGCAGGACGAGGAGAAGACTGACAAGACCAAATCTGATATCGATGGTCTTGTTTGCAAGTTCTGCTCAAAGAAGTTTGCCCGGAAATTGTTGCTTTATGAACATGTGTTAACGAAGCACGAGCCGGGCAAAATGATCCACAATTGCGGTGTGTGCTCCAAAAGGTTCTGCTCAGAGCGAAGACTACGTAAACATCAAATCACTCATTTGCCCAAGAGTGAGAGGATTTTTTATCCATGTCCACAGTGTGACAAGAGGTTTAGAAGCAGGGCAACGATGGAAGTACACAGGAAGGCACTTCATATTGAAGGCAAGAAATTCATTTGTGACCAGTGTGGGAAATCCTACTTGACAAAGTCCGGCCTGAATAAGCACAATATTAGTCACACGGAGGACAGAACGTGTTCTCAATGTCCACATCTAACGTTTGCTCACAAACGACTCTTCACTGACCACATAAAGACACACCAAAAGCTTAAGAACACAAACGGGAGTCAGTGGGAACGACAATTTGTCTGCGCTTTCTGTTCGAGGGTCTTCTATCGTAAATTCTCCCTAAGAGATCACATTTTCACGATGCACGTGAAGAGCGGTCTGGCCTTTGCCTGCTCTAAATGCCCCAAGCGATTCGCCACGAACCGTAGTTTGTATTTTCATGAGCGCACACACTTGCCAGATGCAGAGAGACGCATTCATCGATGTCCCTGTTGCGAGAAGATGTTCCTGAATAAGTCCGGCTTGAAAACTCACATTGatgcagctcacattggcgaaaagcccttcacgtgcgaagagtgtggcatatcattcgtcaccaaagcacgcCTCACTGAGCATCAAGTTGCCCACAGAAAAGAACGACCGTATCAGTGCTCGTCCTGTTCCAAGGCATTCAAAACTCTGAAGTATCTGAAGAACCATAAAAAATGCCACGAAGTCGAAGGTGTCGTTTGTCCACATTGCGGACTAACACTGAAGAACAAAGCAACTCTCAAGCTTCATTTGGTTGTCCATTCGGATGTGAAGAAATACAAATGCCATCACTGTGGAAATGAGTACAAAAGAGTCCAAACATTTAGGGATCACCTTATATCACACACGGGACAGCGACCTTATCAGTGTCCTTTCTGTGATAAAACCTTCGCGAATGGATCAAACTACCGCAGTCACAAGAGAAAGGTGCACCCAGCCGAAGTGGCTGCTCTTGAAGCGGCAGGAGAGCAAATAAGGCCATCAAATATCCCGCGACTTGAGCACTTGCAACCGCAATCTAAGAATTAG
- Protein Sequence
- MLGELLEIANKYFTVSLPEENLLICDDCSNFLLKLENFEERCLKVDIMLKEISEDQNMQESNLQAMRIKYGFDVPEEKYQIQLLEIRKEEDDFSDDVYSDPLDQDIIKTRETVVVKMETPEEEDSESLKKRGRPKKLRESIKRKLQEQEDIESPKKRKRMWKGDGEKKHICSYCSKAFSRQNVMKDHILTKHRKQDMIHACSQCPKRFATSYRLRLHEATHLPDAEKLVHPCPFCDKKFSQKVGAEVHINAMHLGEKSFTCEECGKSFSTKGALTEHKITHTDERPCQCSFCPKKFKNQRQLKQHESSHKESGHACPHCGLKLKSIVTLRMHLLVHSDKKKYKCNYCGNEYKRSKTFKSHLILHTGQRPYECPFCDKTFANGSNCRSHKKKAHPAELAALEATGSQDTENAVERTRSKLDIVNKYFMISLLPFAGPQTSICESCSEFLSRVDAFKDLCMKTDEMFRELLLQEETSEAFLTSIRIKFGIDIEIKDDKFSIDTEIKEEEESVDDFDPLFDCKVASEVEQDEEKTDKTKSDIDGLVCKFCSKKFARKLLLYEHVLTKHEPGKMIHNCGVCSKRFCSERRLRKHQITHLPKSERIFYPCPQCDKRFRSRATMEVHRKALHIEGKKFICDQCGKSYLTKSGLNKHNISHTEDRTCSQCPHLTFAHKRLFTDHIKTHQKLKNTNGSQWERQFVCAFCSRVFYRKFSLRDHIFTMHVKSGLAFACSKCPKRFATNRSLYFHERTHLPDAERRIHRCPCCEKMFLNKSGLKTHIDAAHIGEKPFTCEECGISFVTKARLTEHQVAHRKERPYQCSSCSKAFKTLKYLKNHKKCHEVEGVVCPHCGLTLKNKATLKLHLVVHSDVKKYKCHHCGNEYKRVQTFRDHLISHTGQRPYQCPFCDKTFANGSNYRSHKRKVHPAEVAALEAAGEQIRPSNIPRLEHLQPQSKN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -