Parg011684.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- -
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000025.1:12544044-12546436[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00027 0.011 15.7 0.9 1 23 79 101 79 101 0.98 2 19 2.5e-06 9.8e-05 22.1 1.5 2 23 108 129 108 129 0.98 3 19 0.00023 0.009 15.9 0.7 2 23 136 157 135 157 0.96 4 19 0.0032 0.13 12.3 0.8 1 23 164 187 164 187 0.95 5 19 7.2 2.8e+02 1.8 2.4 2 23 192 213 191 213 0.91 6 19 0.0026 0.1 12.6 0.1 2 20 217 235 217 237 0.94 7 19 1.5e-06 5.8e-05 22.8 0.8 1 23 263 285 263 285 0.97 8 19 0.0047 0.18 11.8 2.1 2 23 292 313 291 313 0.95 9 19 2.6e-05 0.001 18.9 1.3 1 23 319 341 319 341 0.98 10 19 2.4e-06 9.4e-05 22.2 0.5 1 23 348 370 348 370 0.98 11 19 0.00018 0.0069 16.3 0.6 1 23 374 396 374 396 0.98 12 19 0.42 16 5.7 0.6 2 21 399 418 398 421 0.82 13 19 6.2e-05 0.0024 17.7 7.4 1 23 461 483 461 483 0.97 14 19 0.00015 0.006 16.5 2.0 1 23 487 509 487 509 0.98 15 19 8.1e-05 0.0031 17.4 0.2 1 23 537 559 537 559 0.98 16 19 0.00073 0.028 14.4 0.1 2 23 564 586 563 586 0.94 17 19 1.4e-06 5.3e-05 22.9 0.6 2 23 635 656 634 656 0.96 18 19 0.019 0.74 9.9 3.8 1 23 659 681 659 681 0.98 19 19 0.0095 0.37 10.9 1.6 2 23 684 706 683 706 0.94
Sequence Information
- Coding Sequence
- ATGGATCCTTGCATACCGCATCCAATCAAGATTGAACCGCCTGACAGTCCAGAAATCACTGCCGAAAACGATGAATCTATCCTGGGCGATGTGCAGCCAGACTTCTCATCTGTGGCTCTTGAGATCAAAGCCGAGGAGTATCTCGAAGAGGAAAATAGTCCATCTTCCTCCAAATCTCGTGGGAAGAGGGATCGCAAGAAGAAAAAATGGAAGCGCGAAAAGACCGGCCTCACGTACAGTTGTGCCGTGTGCGAGAAGAAGTTCCAGTACATGGCCAGCCTCCGGattcacatgcgctttcactctggcgagaatctgagacagtgttcgcagtgtggaaaacgctatgccacacaatacgcactgaagagacactcccggacgcacaagcaaacaaaaccgagcgtgtgcaagatctgcagtgccacattcgcggatcccaatgacttcaggcgccacaagcgcttccatgccaccggagagccggcgtacgcgtgcaaggagtgcgatgagaccttTGACACATACAATGCCATAAAGCTGCACCGCTCGAAGAGGCACAAGAAGAGCTGGCACTGTCGCCACTGCTGGGAAACCTTCCTCACGGACAAGGAGTATCAGGAACACCGCGTCGTGCACGAGCATCCCGTTTGCCCAAAGTGTCACGTGAAGTTCATGACGCAGGAACTACTGGAAATGCACATGGCAGAAGCCGCAGACCACGAATCGCTTCCGAAAACAGCTTCGCCTGTCGGCGCTGCCAAAGACTCCGCCGGCGCCACAGTGTACGACTGCGATCTCTGTCCGAAGCGTTTCTCGCGGCGCGACAACTTGCTGGAACACCGGCGGCTGCACACCGGCGTGGGCCTGGTGTCCTGCGAGTACTGCCCCATGAAGTTCACCACGCACGCCCGCTTCCGAAAGCATGTTGTGAAGCACACAGAGCGCAAGACCTTCCCCTGTCCGCACTGTGAGAAGGAGTTCGCGTCACAGCACTATTTGGGCATTCACTTGCTcacgcactcggaggatcagctgccgtatccctgtgagctgtgcagcaaggccttctcgcgcagcaacgcgctgcggaatcacatgtacagccacatgaagcagttcccatgctcgaagtgcgcgcttgtctttccatcggatcgacagctgaagaggcatcgcaggatgcacaagctgatgtgcagtcgatgcggcacgagctttgagacaaTGGAATTGGTGCACATGCACTTCGAGGAGTATCATCCGGGCGAAGAGGCGCAGATTCTGCGCGAGCAAGAGCCAGGACAGGGTGAGATTGAGGAAGTGTCCCTTCATCAAGACGGCAATGATCTGTCGCAGGCGATTGGTGTGCAAAAAGTGCATTCGTGTGAATTCTGTGGGAAGGAATTCAACCATAAGTCACACTTGGTCTCTCACAGAAACACACACACGAAAATCTTCAAGTGCTCGAAGTGCCCTGAAGTCTGTGCATCTGAGAGGCAACTCAAGAAGCACAGATTGATTCATAAATTTCCAAAAGAGGCGACAAGCGATGAGATTCTTGAGACGAAGCCCAATGTGAAGCAGTTACAAGAAGAAAGTAAATCTTACTCGTGCAAATTCTGTGAGAAAGAATTTGCAAAACCCTCGGCATTAGGGATTCATGTGAAGACTCATTTAAAGTCCCTTTCTTGCCCGAAGTGTTCCGCAATCTTCCCATCGGCGAGACAACTCCAGAATCACGTGAGAGACAATCACACGACAGAAGACGACGAGGACTCAGAGGAAGTGGAAGAAGATGAGGAGGAGGAAGAAATGCCTGATCTGCACGATGGTGATTCGTCAGAAGATAGTGATAAAGTTATAATTAAGAAAGAGCCTCTGGATGAACCAGAATTTTGGCCTTGTGACATCTGCGGAAAGGGCTTCTCGCGCAGTCGCTCTCTGCACATCCACATAAAAAGCCATTCGGAGTTTCCCTGCAGAAAATGCTCGCAGATCTGCTATTCTGAGCGCGAGTTGAAGAAGCACAGGAAAGTGCACAAAACCACGTGCAAAGTGTGCAGGATGGAATTTGAGACGGCGGATCTGCTGAAGCTACACTATCAGGAATGTCATCCAGAGGACAGAAGGGCGAAGAGAAAGGTTCAACCCGCTGAAGTTTTCCAAGATCCATTGATGCTGACTGAAAATGACTTTCTGGATCCCTTGGTAGATTGA
- Protein Sequence
- MDPCIPHPIKIEPPDSPEITAENDESILGDVQPDFSSVALEIKAEEYLEEENSPSSSKSRGKRDRKKKKWKREKTGLTYSCAVCEKKFQYMASLRIHMRFHSGENLRQCSQCGKRYATQYALKRHSRTHKQTKPSVCKICSATFADPNDFRRHKRFHATGEPAYACKECDETFDTYNAIKLHRSKRHKKSWHCRHCWETFLTDKEYQEHRVVHEHPVCPKCHVKFMTQELLEMHMAEAADHESLPKTASPVGAAKDSAGATVYDCDLCPKRFSRRDNLLEHRRLHTGVGLVSCEYCPMKFTTHARFRKHVVKHTERKTFPCPHCEKEFASQHYLGIHLLTHSEDQLPYPCELCSKAFSRSNALRNHMYSHMKQFPCSKCALVFPSDRQLKRHRRMHKLMCSRCGTSFETMELVHMHFEEYHPGEEAQILREQEPGQGEIEEVSLHQDGNDLSQAIGVQKVHSCEFCGKEFNHKSHLVSHRNTHTKIFKCSKCPEVCASERQLKKHRLIHKFPKEATSDEILETKPNVKQLQEESKSYSCKFCEKEFAKPSALGIHVKTHLKSLSCPKCSAIFPSARQLQNHVRDNHTTEDDEDSEEVEEDEEEEEMPDLHDGDSSEDSDKVIIKKEPLDEPEFWPCDICGKGFSRSRSLHIHIKSHSEFPCRKCSQICYSERELKKHRKVHKTTCKVCRMEFETADLLKLHYQECHPEDRRAKRKVQPAEVFQDPLMLTENDFLDPLVD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -