Parg006935.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phlebotomus argentipes
Gene Symbol
-
Assembly
GCA_947086385.1
Location
CAMTYR010000037.1:307157-309685[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 1.2e-05 0.00046 20.0 2.2 3 23 68 88 66 88 0.93
2 20 1.3e-05 0.00051 19.8 2.9 1 23 94 116 94 116 0.98
3 20 0.00018 0.0072 16.2 1.7 2 23 135 156 134 156 0.96
4 20 0.0024 0.094 12.7 3.6 2 23 164 185 163 185 0.96
5 20 0.19 7.3 6.8 0.8 1 23 201 223 201 223 0.88
6 20 1.9e-07 7.4e-06 25.6 1.7 1 23 235 257 235 257 0.98
7 20 0.0024 0.095 12.7 3.8 1 23 261 283 261 283 0.97
8 20 0.00015 0.0059 16.5 3.1 1 23 289 311 289 311 0.96
9 20 0.00036 0.014 15.3 3.6 1 23 317 339 317 339 0.96
10 20 1.1e-05 0.00042 20.1 0.3 1 23 345 367 345 367 0.99
11 20 0.0085 0.33 11.0 0.5 1 23 455 478 455 478 0.92
12 20 2e-05 0.00078 19.3 1.2 3 23 495 515 493 515 0.97
13 20 7.5e-05 0.0029 17.5 0.1 1 23 521 543 521 543 0.99
14 20 1.2e-05 0.00046 20.0 0.3 1 23 549 571 549 571 0.98
15 20 2.1e-05 0.00081 19.2 1.2 1 23 577 600 577 600 0.97
16 20 3.6e-05 0.0014 18.5 0.4 1 23 606 630 606 630 0.98
17 20 0.0005 0.019 14.9 0.4 2 23 640 661 640 661 0.98
18 20 0.00015 0.006 16.5 0.7 3 23 667 687 665 687 0.96
19 20 1.8e-05 0.00069 19.4 2.2 2 23 694 715 693 715 0.97
20 20 3.7e-05 0.0015 18.4 1.9 2 23 723 744 722 744 0.97

Sequence Information

Coding Sequence
ATGAGTGCAAAAGACCAACCAGAGATTATTCACGTGAACATCGCCCCGGATTTCATCTTGTGCAACGTGGAGTACGAGAGTTGCGGCGAGAGTGGTGAGGAAAAGGAGATGAGAAAGAAGACTGAGACTCCGCCAAAGGATGGAAGTGTCATCAAAGAGACGAAGAGCAAGAGGAAGAGTGAGGCTGCCAAAGAGATCTTCTGCCAGACGTGCGGGAAGATGTTTACGAGGCAGAGACATCTCACACGTCACGAGGTCATTCACACGGGCGAGAAGCCTTTCAGCTGCGATGTGTGCCAGAAGAGATTCAACAGGAAGGACAAGCTGGTGAACCACCGGCGTTACCACAAGGTGCCAAAGGAGGAGGACGAAGCGGAGGAGAATGAGGACAAGGACGAGCTGAAGTGCAACTTCTGCGGTGAGACGTTCAGTGACAAGGATCAGCTGCGATTCCACAAGAAGATTCACGCCAGCTCGCATGAGCTGCTCACCTGCATGATATGCAAGAAGATGTGCAGCACCACTGATGAGCTGCGGCAGCACTACTTCACCCACACTGGAAGCGTGCAGAGCAAGGAGAGCGGCGAGAAGGCGCAGGTGTTCGATTGCCAGTATTGCTACAAGAGCTTCCTCAACGGCGAACTCCTGCGGGAGCATCTCGTGTTCCACGGCATGACGCCCTTCAGCGCGGACGACGTCGTGCACAAGTGCACCATCTGCGAGAAGACCTTCAGCCAGGCCGCTTCGCTGCGCCAGCACATGATCACGCACAGCAGAGATTATCCGTGCACCTGTTGCGAGATGACGTTCAATCGCCGAGACAAGCTCAGCACGCACATGAAGATGCACGAGAACGCAAAGGAGTTCCTGTGCACGAAGTGCGGCCGCAGCTTTGAGAACATGTTTAAGCTGGATCATCACATGCGCGTGCACTTCGGGAAGACTGACCACATGTGTCTGATCTGCAACAAGCACTTCCAGATGGCGAAGAATCTCAAACGCCACATGGTTGTGCACACAGGCTTGAGACCATATCAGTGTGACCTTTGCGGCAACACGTATCCGAGGAGAGACAAACTCACGGCTCATCTTAAAGTGCACGCGAACCGAGGGGAGATGGCTCTGAAGGATGCCTTTGCGCCGAAGAAGCTTATAGAACCGGTTTATCCGGTGTTTTCGGATGATCCGACAGTGAGAGATGATGAGGAACGTGGTGAGGAATTAGAAGATGCTCAAGTGGAGGAGGAAAAACCCTCACCGCTGCCTGGAGAGGCTCTGGAGGATTCGTCAGAGAATCTGGGACAGACTCTCAATCATCCATACATTGATCCTGACGACGAAGACGACGACGATGAGGAGATCTACGACTGTGTTTACTGCTACAAGAGCTTTCTGCAGCGAGATCTTCTGCAGACGCACTTGGAAGATGTCCACGATGCCCACTTGACGGAGAAGATCTTCCTGGAGCAGGCGCAAGTGTGTTGTCCCATCTGCAACAAGGAGTACGGTAGTCAGCGGGCGCTGAAGCGACATCTCCAGACGCACAGCAAGGAGAAGACGTACAAGTGTCCAGAATGTGCCATGAGCTTCGATCGGTTCTATCCACTGGTGGCTCACATGAAAGTCCACCAGCGCTCGAAAGCCTTCCCATGCAAGCTCTGCGGACGCTCCTTCGACGATGCCACGCGTCTGGAGTACCACATGAAGATCCACACGAATCAGAAGGACTTCAAGTGCAAGATCTGCAACGTTGGCTTCCAGTCGACGAAGAATCTGCGGCGCCACATTCAGTCCATTCACGTGTCGGAGAAGCCCTTCAAGTGCCCCGAGGAAGGATGCAATTATGCGTTCAGTCGCAGAGACAAGTACAGCGCTCACGTGCGAAGTCATCAGACGGTGCCGAAGAAGAAGTCGCGGAAGTGCGTCAAGTGCCAGATGGTGTTCAAGAGCAGTGAAGAGGTGAAGGAGCACATGTTGGTGCATCTGAAGTTTCTCGACTGTGATCAGTGCGAGGAGAAGTTTGCCAGGAAGAAGGACTTGGCGCAGCACAGGAAGTCACATGAGAAGTCAGAAGATGTTTCGTGTTCGGTGTGCAGTAAGAAGTTCAAGCTCAAGCGATATCTCAAGGCGCACATGAAGACACACGGGAAGGTGGAAGAGCTGCAACAGTGTGAACATTGCGAGGAGACGTTCGAGACTGAGAGTCAACTGGAGCAACACACGAAGAGTCACATTGATCGCAGTGAAGCCATAGGACTGAATGTGTCGATAGAACAGGAAAGACAGCCTAGTTTAGAAGACATTCAAACGTCCAGCCAAAATAGTTAA
Protein Sequence
MSAKDQPEIIHVNIAPDFILCNVEYESCGESGEEKEMRKKTETPPKDGSVIKETKSKRKSEAAKEIFCQTCGKMFTRQRHLTRHEVIHTGEKPFSCDVCQKRFNRKDKLVNHRRYHKVPKEEDEAEENEDKDELKCNFCGETFSDKDQLRFHKKIHASSHELLTCMICKKMCSTTDELRQHYFTHTGSVQSKESGEKAQVFDCQYCYKSFLNGELLREHLVFHGMTPFSADDVVHKCTICEKTFSQAASLRQHMITHSRDYPCTCCEMTFNRRDKLSTHMKMHENAKEFLCTKCGRSFENMFKLDHHMRVHFGKTDHMCLICNKHFQMAKNLKRHMVVHTGLRPYQCDLCGNTYPRRDKLTAHLKVHANRGEMALKDAFAPKKLIEPVYPVFSDDPTVRDDEERGEELEDAQVEEEKPSPLPGEALEDSSENLGQTLNHPYIDPDDEDDDDEEIYDCVYCYKSFLQRDLLQTHLEDVHDAHLTEKIFLEQAQVCCPICNKEYGSQRALKRHLQTHSKEKTYKCPECAMSFDRFYPLVAHMKVHQRSKAFPCKLCGRSFDDATRLEYHMKIHTNQKDFKCKICNVGFQSTKNLRRHIQSIHVSEKPFKCPEEGCNYAFSRRDKYSAHVRSHQTVPKKKSRKCVKCQMVFKSSEEVKEHMLVHLKFLDCDQCEEKFARKKDLAQHRKSHEKSEDVSCSVCSKKFKLKRYLKAHMKTHGKVEELQQCEHCEETFETESQLEQHTKSHIDRSEAIGLNVSIEQERQPSLEDIQTSSQNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-