Basic Information

Gene Symbol
-
Assembly
GCA_963971545.1
Location
OZ020604.1:13836347-13841227[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0071 2.5 11.1 0.0 1 23 110 133 110 133 0.95
2 15 0.0018 0.62 13.0 3.6 2 23 182 204 181 204 0.96
3 15 0.041 14 8.7 0.2 1 23 322 345 322 345 0.93
4 15 0.00061 0.21 14.4 2.1 1 23 472 495 472 496 0.93
5 15 0.00047 0.16 14.8 1.7 2 23 546 568 545 569 0.96
6 15 0.0035 1.2 12.1 1.4 1 23 657 680 657 680 0.95
7 15 0.89 3.1e+02 4.5 7.1 1 23 689 711 689 712 0.95
8 15 0.00032 0.11 15.3 0.1 1 23 766 789 766 789 0.93
9 15 0.091 32 7.6 4.5 2 23 839 861 838 861 0.96
10 15 0.00016 0.054 16.3 0.4 1 23 925 948 925 948 0.97
11 15 0.015 5.2 10.1 2.1 1 21 1000 1020 1000 1021 0.95
12 15 0.0044 1.5 11.7 0.2 2 23 1081 1103 1080 1103 0.95
13 15 0.63 2.2e+02 5.0 2.1 2 23 1153 1175 1152 1175 0.94
14 15 4.1 1.4e+03 2.4 0.1 2 23 1309 1331 1308 1331 0.84
15 15 0.055 19 8.3 5.9 2 23 1381 1403 1380 1403 0.95

Sequence Information

Coding Sequence
atggacCAACTCTTTATGTTTTCAAATGAGTATACTATGGATGATGCCGAGGATGCTGCGAGAAGAAGCAACAAAAATGAAGCAGAAATTAAAAACGAACCTAACGACATTGTGGATGATGATGGTGATGATGATAGCTATATAATGCCAGAATCTTTATTGCAACAAATGACATCTACACCCGATGCAGATGGTGAAGATGAtaatactatttttaattttggaattGCTCCAAATAGAGATACACGACAGGCGACATCTGTACCGAAATCATTCAACCCAAAGCATCCTCAAGATGTCAACGTTAATTATGATATAGCAATAATGTTTATTTGCCCATCTTGTGGATCTGAATTTGATACACAAACGGCCTGGAAGGCTCACATTAACGGTGTGCATGACTTTAATACACGGCGTGGGTTGAATTTTGTGCCGATAGGCAAATTGTATCACAGATGTCTGGAGTGCAACAAACCTATTGCCATGCATGCAATGGAGAATTTGCTAAAGCATAAATTCACTCATCTACCACATCGTTGCACCAAATGTAAAATATGTCAACGTCGGTATAAGTATCGACAGGATTTAATTGTGCATCTGCGTTTGTGTCACCGCGAAGAAGTATTGGCAATGACGGCAATTGTAACAAACACAGCCAACAAAGACAGccacaaacataaacatgaaaTCACACCAAATGCACGGTTGGAGATCAAAGATATTCAGGGAAATGCAGTTGACATATTCGAAAACACTTGCGATAGCGTTGAGGTTAAAAATGAACCATTCGATCCCGATGATCCAGACGGTGACGATTTGCTTGAACCATCGgaaaataaatctaaatttgCTACGGCCTCTATTCTTGAAGGTGCTCTCAGTCGAAGTGCTTCACAAGGTACGGATCAAATGAAAAGTGGCAATGGAGGCGCTACTGACAAACAATGTGAAAAGCATATACAATATATTTGCCCCGTGTGCCACACGGAATTTTCGATTAAGAATGAATGGCTCGAACACGTACAGGAAATGCATAATTTTTGCTCAGTAACTGGTCTCGGATTCCGACAGCACAGCAATGTAACAGCTGAATGTCTGGAATGCAAGAGGgttaTGCCTGATAAATCAATTGAAGAATTGCAGCTACATAAATTTTCGCACCTCCCTTGTAAAACGTGGCTACGCTGTAAGCTATGTTTAGGTTTATTCAAAGGTCACAAAGATATTATAAAGCATTTGCTTAATCAACATCGGTTTGATGATGAATACCAAATGGAAGACGATGAAGACAACAATGATGATGCTTCTATTGATCCATTCCCAATACCAACGAATGACAACGACAACGATATATCTCATACTGAAAGAAAAGGAAAGAGCGAAGTTCGTGATATTTATGAGACGCAAATAGATTACTTATGTCCAAAGTGTGGGAAAGagtttttccaaagaaaaatgTGGCGGAAGCATATTGTAAAAGAACATCACTATACCGATTTGAAGACCCTTTGTTTCGTAGTATTAAATGAGCATCAGCTTCAATGTCGTTTGTGcggaaaaataataactaaCGCATATGGCGTGCAAAATGCGCAACAACACTATTTCACACATTTGCCACACAAAGCATATATACGTTGTCGCATATGTGCCAAATCTTATACGGATCGTAAAGGTTTGGTTAAACATTTGCGTAAGGTACACCATATAAGTCCTAAAACTGCTGCAGCGATTGCTGCCAAGAACTTACGATCACAAACCACATTCcagcaaatacaaaaaacgCCGAAAGTGTCAAAAGCACTGCCTCGTACGGCACCTGTTAAAGAAATAGTAAGATATAACGGTGTCATATTTGAGATACAGTTCTTGGATGAAGACAATGATGATGGCGCTTACTCAATGGATGATGAGTCTAGGTCCTTTGGTGATGGGAAAAATGATAGTTTTGCCATACCAACCAAACGACATGTCTGCGCAGATTGTTATTCAACATTTAGTACAGAACAAGCTTTACAAAAACATACTAGAGAACAACATGACTTCAAGAAACCCTCTCAAGCGCACGTCTGCACAATGTGCTTTTGTACGTTTGAATCGGCTGGGGCATTACATGATCATAAGCTTAAGCATCACTCAAAACATACAACTTCGACCAATTCCAACGACAACAATAATGATGACCATGACGGAGAAGAAGATTTGCTTTTGGTACCTACTGGGAATGAGGACATCAACACCAACTCCAGTTCATTTGCTGGTGTAACGCAAGCAAATATCGAACAATATTTCTGCTATCTATGTCCGGCATGCGGTGAAGAGTTCAAATCTCAATACGAGTGGCGTCGTCATATCAACGATATACATTATTTCGATCGCCGTTACGAACTCAATTTTCGGCAAATtgataaatttcattttcaatgttTGGAGTGTAAGGAAATTGTAAACAGTGCTAAATTAAAAGGTCTTCAAGACCATAAATTCCGTCACTTGCCGTACAAGTTGTACATAAAATGTCGACTCTGCAGCACATGCTATAATCACAAGCCCAATATGGTCACACATCTGCGTATACGCCATAATTTGGTCGAACCGAATATTAACACCTCCATGTCAGCGTCGCCACAAATGCGCTTTAACACAATCAACTCGTATGATATGTCAACACCATTACCATCATCGACACGTCAGTCATTTAACAATTGTAAACTTTTAACTACGGAAGACATCATTTCGAATCACAATGCTGTCGATCACGAAACAATTACCTATCGCTGCCCGCAATGCAATGAATCATTTGATACACACGCCCTATGGCGTCAGCACATTGTCACTGCACATAATCTGAACAGTAGGCAAGGTTTGAATTTCCGTCAACTGGATGCCCACCATTATATTTGCTTGGAATGTTATAAGCGCGTCACGGTGACACACACAAAGGGTGCAATTGGTCAACTACAGTCGCATAAATTCCGTCATTTGCCGTACAAATCATTCAGTTGCACCAAATGCAATGAGCTTTTTGTACGCAAGCAAATGTTCTTCAAACATCTTAATCGCGCCACCAACAGATGTCCATTGTGGGGAAATGAGCGTGCTCCCAATTTGAATAACAAAGCAAAGAATTCAAATATGAGCTTAATGCGCGCAATGTCAGCACATTGTGCGAATACCATTCCGGCTGGAAAGCATCTTAACTTCTCTATAACTTCCAAGGAGAAATGCCCCTACATCATACAATGCCCACAATGTGGCATtaaattcgaaaaatggcatCCGTGGCGCGAGCACATCGAAAAAGTGCATGCTTTACATAGTATGGCATCGCTTAAATTCAAAAAGATCAACGATCATTTGCACATTTGTATACAGTGTAAGGAACGCGTTACGGGCGCCAATTTCATAAACTTGCAAACACACCGTTTCAAACATTTGCCGTACGGCACATATCTCCATTGTCGCTACTGCGATGTGAGATATTACTATATGATCAATATTATCAAACATATGAAACAAAAGCATCCCAATCATGGCATGGAACAGCTCGAATTACAGTTGGAGAGCGCGGCTGATGAAGAGGCTGACTTTTCGCCGGATGCAGCCGGCATGGATGTGGATAATGAGGGCGACGTAAAGACGAAGCAGCAGGATAATGAAAACGCTGCCTTTGAGGATGATGATAATCAACTGTTGGATGATGATAAAGCTGTGATcattgatgatgatgatgatgaagaaGATGATGACGATAATGATGGTGATGACGGTGAAGTTGAAGTTGAAGTTGAAGAGGAAGATGATGATGCTGAGGATGTTGATGACGACGATGGCCGCAAGGATGAAAATGCTGAGAAAGCACTTTTGACCAACGAGGGGGAGTGTGGTTTGAGTTCTGAAGCTTCtataattacttatattataCAATGTCCGCAATGTGGCATTAAAAACGATAATTGGAATTTGTGGCACGAACACATCGCCAATGCGCATGCACTCAACGAACGCGAAACGCTTAATTTTACGAAAATAAATGATTCATTAGAAGAATGCAAAGAGTGCAGCGAGCACGTAAATGCCACATCTTTCTTTAACCTGCAAATCCACAAGTTTAAACATTTACCATTCGCAAATTATTTGCATTGTCGCTATTGTGACGCTAAGTTTAATCACAAGTCACACATCGTTACACACTTGAAATCGATTCATCCCGAGCAAGCAattcagcagcagcagcagcagcaggagtCGACCGATGGACTTGAAATGGATTTACCAGAGAAcaaaaaagaagtgaaaatcAAGGAGGTGGAGAAATCGGATGTTGCAGTTGAAACAAAGGATGATGGCAATTTGAAGATTGATGAAGTAGCTGCTGttgatgataatgatgatgatgacgacgacgacgacgatgatgatgatgacgatgatgatgatgatgatgatgacgaagATGAAGAAGATGGTGATGATTtggatgatgatgatgataacgaagagcaaaaaaataatggcGAAGATGTTACCGAACGTATGGATGTTGATGAAGATTTTGAAAATGccgacgatgatgatgatgaggatGAAAATGACGACGAAGACGATGTGGATGATGATGACGACGACGAAGGGGATGATGATGAGATAGAAACTTATGGAAATGCGGATATTGGAGAACCAGAGCGCAATAGTGTAATTAGAAATATGGGAATGCCAAGGAAACCCATAGAGGCAACAGATGAAGTCGATGATTCGGATAATCAATTCGTGCTaggttaa
Protein Sequence
MDQLFMFSNEYTMDDAEDAARRSNKNEAEIKNEPNDIVDDDGDDDSYIMPESLLQQMTSTPDADGEDDNTIFNFGIAPNRDTRQATSVPKSFNPKHPQDVNVNYDIAIMFICPSCGSEFDTQTAWKAHINGVHDFNTRRGLNFVPIGKLYHRCLECNKPIAMHAMENLLKHKFTHLPHRCTKCKICQRRYKYRQDLIVHLRLCHREEVLAMTAIVTNTANKDSHKHKHEITPNARLEIKDIQGNAVDIFENTCDSVEVKNEPFDPDDPDGDDLLEPSENKSKFATASILEGALSRSASQGTDQMKSGNGGATDKQCEKHIQYICPVCHTEFSIKNEWLEHVQEMHNFCSVTGLGFRQHSNVTAECLECKRVMPDKSIEELQLHKFSHLPCKTWLRCKLCLGLFKGHKDIIKHLLNQHRFDDEYQMEDDEDNNDDASIDPFPIPTNDNDNDISHTERKGKSEVRDIYETQIDYLCPKCGKEFFQRKMWRKHIVKEHHYTDLKTLCFVVLNEHQLQCRLCGKIITNAYGVQNAQQHYFTHLPHKAYIRCRICAKSYTDRKGLVKHLRKVHHISPKTAAAIAAKNLRSQTTFQQIQKTPKVSKALPRTAPVKEIVRYNGVIFEIQFLDEDNDDGAYSMDDESRSFGDGKNDSFAIPTKRHVCADCYSTFSTEQALQKHTREQHDFKKPSQAHVCTMCFCTFESAGALHDHKLKHHSKHTTSTNSNDNNNDDHDGEEDLLLVPTGNEDINTNSSSFAGVTQANIEQYFCYLCPACGEEFKSQYEWRRHINDIHYFDRRYELNFRQIDKFHFQCLECKEIVNSAKLKGLQDHKFRHLPYKLYIKCRLCSTCYNHKPNMVTHLRIRHNLVEPNINTSMSASPQMRFNTINSYDMSTPLPSSTRQSFNNCKLLTTEDIISNHNAVDHETITYRCPQCNESFDTHALWRQHIVTAHNLNSRQGLNFRQLDAHHYICLECYKRVTVTHTKGAIGQLQSHKFRHLPYKSFSCTKCNELFVRKQMFFKHLNRATNRCPLWGNERAPNLNNKAKNSNMSLMRAMSAHCANTIPAGKHLNFSITSKEKCPYIIQCPQCGIKFEKWHPWREHIEKVHALHSMASLKFKKINDHLHICIQCKERVTGANFINLQTHRFKHLPYGTYLHCRYCDVRYYYMINIIKHMKQKHPNHGMEQLELQLESAADEEADFSPDAAGMDVDNEGDVKTKQQDNENAAFEDDDNQLLDDDKAVIIDDDDDEEDDDDNDGDDGEVEVEVEEEDDDAEDVDDDDGRKDENAEKALLTNEGECGLSSEASIITYIIQCPQCGIKNDNWNLWHEHIANAHALNERETLNFTKINDSLEECKECSEHVNATSFFNLQIHKFKHLPFANYLHCRYCDAKFNHKSHIVTHLKSIHPEQAIQQQQQQQESTDGLEMDLPENKKEVKIKEVEKSDVAVETKDDGNLKIDEVAAVDDNDDDDDDDDDDDDDDDDDDDDDEDEEDGDDLDDDDDNEEQKNNGEDVTERMDVDEDFENADDDDDEDENDDEDDVDDDDDDEGDDDEIETYGNADIGEPERNSVIRNMGMPRKPIEATDEVDDSDNQFVLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-