Basic Information

Insect: Philopedon plagiatum
Gene Symbol: topi
Assembly: GCA_963971165.1
Location: OZ020194.1:83849197-83854861[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.49 96 6.1 1.2 1 21 25 45 25 50 0.95

2 18 1.9 3.7e+02 4.3 0.3 1 9 75 83 75 83 0.92

3 18 0.00017 0.034 17.0 1.3 1 23 102 125 102 125 0.97

4 18 2.8 5.5e+02 3.7 3.2 3 23 133 154 132 154 0.94

5 18 0.001 0.19 14.6 1.5 3 23 163 185 161 186 0.92

6 18 0.0092 1.8 11.6 2.1 1 23 193 215 193 215 0.94

7 18 2.8e-06 0.00055 22.6 2.9 1 23 221 243 221 243 0.99

8 18 0.0045 0.88 12.5 0.3 1 23 249 271 249 271 0.94

9 18 0.17 32 7.6 0.0 1 21 327 347 327 348 0.94

10 18 1.8e-06 0.00035 23.2 0.9 1 23 375 398 375 398 0.94

11 18 0.002 0.39 13.6 0.5 2 23 405 427 404 427 0.93

12 18 4.4e-06 0.00085 22.0 0.9 1 23 434 457 434 457 0.97

13 18 0.013 2.5 11.1 1.7 2 23 464 486 463 486 0.96

14 18 0.00029 0.056 16.3 0.3 3 23 495 518 493 518 0.91

15 18 0.0008 0.16 14.9 2.1 1 23 525 547 525 547 0.95

16 18 0.0011 0.21 14.5 2.1 4 23 557 576 551 576 0.94

17 18 0.00065 0.13 15.2 0.3 1 23 582 604 582 604 0.96

18 18 0.00023 0.045 16.6 4.2 1 23 610 633 610 633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.49	96	6.1	1.2	1	21	25	45	25	50	0.95
2	18	1.9	3.7e+02	4.3	0.3	1	9	75	83	75	83	0.92
3	18	0.00017	0.034	17.0	1.3	1	23	102	125	102	125	0.97
4	18	2.8	5.5e+02	3.7	3.2	3	23	133	154	132	154	0.94
5	18	0.001	0.19	14.6	1.5	3	23	163	185	161	186	0.92
6	18	0.0092	1.8	11.6	2.1	1	23	193	215	193	215	0.94
7	18	2.8e-06	0.00055	22.6	2.9	1	23	221	243	221	243	0.99
8	18	0.0045	0.88	12.5	0.3	1	23	249	271	249	271	0.94
9	18	0.17	32	7.6	0.0	1	21	327	347	327	348	0.94
10	18	1.8e-06	0.00035	23.2	0.9	1	23	375	398	375	398	0.94
11	18	0.002	0.39	13.6	0.5	2	23	405	427	404	427	0.93
12	18	4.4e-06	0.00085	22.0	0.9	1	23	434	457	434	457	0.97
13	18	0.013	2.5	11.1	1.7	2	23	464	486	463	486	0.96
14	18	0.00029	0.056	16.3	0.3	3	23	495	518	493	518	0.91
15	18	0.0008	0.16	14.9	2.1	1	23	525	547	525	547	0.95
16	18	0.0011	0.21	14.5	2.1	4	23	557	576	551	576	0.94
17	18	0.00065	0.13	15.2	0.3	1	23	582	604	582	604	0.96
18	18	0.00023	0.045	16.6	4.2	1	23	610	633	610	633	0.97

Sequence Information

Coding Sequence: ATGTTTCTTAAAATTAGGGTTGTTTTATCACCTGAGAGGGTCAGCCAAGAGCAAAATTATACCTGGGTAGCATATCAATGTGTTCAGTGTTCGTTGATTGTGGACACCTATGAAAAATTGACTGCTCATCAGAAAGAGTGTTTCCTTCATAATAATAAGATAGTGAAGGATATTAAATGCGAAGATTCTGCtgtaaaaaatgaaaacaaaaagcAAACTCGTTTCGTTTGCTCGGAATGTGGAAAATCAGACTGGATCTTAAAGCAGCATGTCGACACAATACACCGAGGAATCGTCAATTACTTTAAGTGCGACATTTGTGGTGAAAACTACAGAAGCAAGCGTACGAtggaaaatcacaaaaaaagtaTTCATTTTAAGACGTTTAACAAATTCTGTGATATTTGCAATAAAGGATTCCTTTGTAAAAGTAAGTTAGAAACTCATAAAAAATCGGCACATGGAGAGGAGGTTACTATCATTGCTTGCCCACAGGAAGGATGtagaaaaacctttaaatctACGGGACATTTAAGGTACCATATATTGGCCCATCACACTACAGATAAACCTCAATTTCTATGCGGAAAGTGTGGAAAAACGTACAACCATCCTGCTATCTTTCGAAATCACCTGCGGTTTCATGAAAAAGGGTACAAGTACAAGTGTCCTCATTGCGAGAAAACTGTAACTACAAAAGTTGGTTTGAGACATCATATACGCATCCACACTGGTGAAAAACCGTACGTTTGCGAACTGTGCGGCCTAAGTTTTAACAGAAGAAATATTCTTAAGAGTCATAAGGTGGTTCACACGAAAGAAAAACCTTTTGCTTGTGTCATGCAGGGTTGGTCAAAGAAACCGAGAACCAAAAACAAGGAGATGATGAAAGAGAGTCATCTGAAACCAACAGAAAATGAAGTTTGCTTAAAAGCAGAAGGCCATTTTGTccTAAAGCCAAACTATACCTGTGTAGTCTATCAATGTGTTCAATGTGCTTTGCGTGTGGACaccaaagaaaatttaattgctCATGAGAATAAGTGTTTTCTTTATAACAATAAGACAGTAATTAAATGCGAAGATTTGTctgtaaaagaaaaataccaGAAGCAAACTCGTTTCGTTTGCTCGGAATGTGGGAAAACATTTTCCGGACAAAAATACTTAACCAGACATATTTACTATGTTCATACGCGACCGGAATTGACTACCTGTAAAGAATGCGGAAAAAGATTTTCTAGAGACTGGATTTTAAAGCAACACGTCGACACAATACACCGAGGAATTGTCGGTTACTTTAAGTGCGAAATTTGTGGTGAAAACTACAGAAGCAAGAGTAATAtggaaaaacacaaaaaaattgtccATTTTAAGACGTTTAACAAGTACTGTGATATTTGCAATAAAGGATTTATTTGTAAAAGCTTATTAGAAGTTCATAAAAAGTCGGTGCATGAAGGAGAGGTCACTATCATTGCTTGCACACAGGAAGGATGCAAGAAGACGTTTCGATCTACGGGAAATTTGAGGTACCATATGTTGGCCGAGCACACTACAGATAAAGCCCAGTTTTTGTGTGGAGAGTGCGGAAAAACGTACAACCATCCTTATATCTATCAGAAGCACCTCCGGCGTCATGAAAAAGGGTGCTCTCAGTACAAGCGTCCTTATTGCGAAAAAACTGTAACTACCAAATTTAGTTTGAGACATCATATACGCATCCACACAGGCGAAAAACCGTACGTTTGCGAACTGTGCGGCCTTAGTTTTAACAAAGGAAATAATCTGAAGACTCATAAGGTTGTTCACACGAAAGAAAAACCGTTTGCATGTAAGTTTTGCGACAAGAAATATACCCAGCGAAGTCCTCTTAGTCAGCATATCCGTAGGTGCCATGCAGGGTTAGTCAAAGAAAGCGTGaaccaaaaacaaagaaatgatAAAGAAAACTCGTCTGAAATCAACAGAGAATGA
Protein Sequence: MFLKIRVVLSPERVSQEQNYTWVAYQCVQCSLIVDTYEKLTAHQKECFLHNNKIVKDIKCEDSAVKNENKKQTRFVCSECGKSDWILKQHVDTIHRGIVNYFKCDICGENYRSKRTMENHKKSIHFKTFNKFCDICNKGFLCKSKLETHKKSAHGEEVTIIACPQEGCRKTFKSTGHLRYHILAHHTTDKPQFLCGKCGKTYNHPAIFRNHLRFHEKGYKYKCPHCEKTVTTKVGLRHHIRIHTGEKPYVCELCGLSFNRRNILKSHKVVHTKEKPFACVMQGWSKKPRTKNKEMMKESHLKPTENEVCLKAEGHFVLKPNYTCVVYQCVQCALRVDTKENLIAHENKCFLYNNKTVIKCEDLSVKEKYQKQTRFVCSECGKTFSGQKYLTRHIYYVHTRPELTTCKECGKRFSRDWILKQHVDTIHRGIVGYFKCEICGENYRSKSNMEKHKKIVHFKTFNKYCDICNKGFICKSLLEVHKKSVHEGEVTIIACTQEGCKKTFRSTGNLRYHMLAEHTTDKAQFLCGECGKTYNHPYIYQKHLRRHEKGCSQYKRPYCEKTVTTKFSLRHHIRIHTGEKPYVCELCGLSFNKGNNLKTHKVVHTKEKPFACKFCDKKYTQRSPLSQHIRRCHAGLVKESVNQKQRNDKENSSEINRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -