Pcog070689.1
Basic Information
- Insect
- Philonthus cognatus
- Gene Symbol
- -
- Assembly
- GCA_932526485.1
- Location
- CAKOBG010000461.1:893164-901396[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.2 41 7.2 5.7 1 23 64 86 64 86 0.97 2 16 0.59 1.2e+02 5.7 0.7 1 21 91 111 91 114 0.79 3 16 1.3e-05 0.0027 20.3 4.0 1 23 119 141 119 141 0.98 4 16 0.0074 1.5 11.7 1.2 2 23 166 187 165 187 0.96 5 16 0.019 3.9 10.4 1.0 2 23 193 216 192 216 0.90 6 16 0.0031 0.64 12.9 1.1 1 23 222 244 222 244 0.97 7 16 0.015 3.1 10.7 0.8 1 23 249 272 249 272 0.96 8 16 1.5e-07 3.1e-05 26.5 1.6 1 23 277 299 277 299 0.98 9 16 0.004 0.82 12.5 1.1 1 22 324 345 324 345 0.94 10 16 0.00048 0.1 15.4 2.5 1 21 354 374 354 376 0.95 11 16 0.017 3.6 10.5 0.6 1 23 381 403 381 403 0.98 12 16 1.4e-05 0.0028 20.3 1.1 2 23 409 430 408 430 0.97 13 16 3.5 7.3e+02 3.3 3.5 1 23 439 461 439 461 0.96 14 16 7.6e-06 0.0016 21.1 0.5 1 23 469 491 469 491 0.99 15 16 3.7e-06 0.00077 22.1 0.4 1 23 525 547 525 547 0.95 16 16 1.9e-05 0.0039 19.8 0.5 3 23 555 575 553 575 0.98
Sequence Information
- Coding Sequence
- ATGGTATCACGACAAAGGGACGCGGACATATGGACGCGCGACTTTCGGATGCGAATCAACAGTAAAGCGAGTTTAGTAACTTCGTCCGAATCGGAAGATCAAAATTCTTCGAAAGACTCACCGCTGTTCGTCTACAAAAAACACATGGAGCGCTACTTAGAAACGTCCAGCAAGAACCCGAGCCTGGAACACGTGTGTAAAATATGCAATAGGAGATATCTAACCAAACGAGGAGTGCATAATCACATGAAAAAGCACACGACTTTAAAATACGAGTGCGAGTTTTGCGGACTCAAGTACGCCACGAAGTTTCTAGAGATGCAGCACAAAAACGAATCCCACGTGGACGAGATGTTTAAGTGTAAAATATGCGGGTTGCCGTTTCACAGGAGATCAAATCTGCGTTACCACACGATGAAACACGATCCCAACTACAAACCGCCGGTTTACAAGTGCAATACCTGTAGCTACGCAAGCGGTTGCCAGAGTAGAATCGAGTGTGATTTATGTGAAGCCACTTTTGAAACAACCTACGATCTTTGCAGTCACAAAAAATTGCACAAACCGCGCCAACTCCCTTGCCCTAGATGCACCAAACCCTTTTACTTCGAGCTGCTTCTTAAAAAACACTTGGAAACGTGCCCTCACGACCCAACCAAGCTCTTCGCGTGCAAACTATGCGACAAGAAATACCTAACGAGAGACAGCTACGCCAACCACATAAAATCCCACTTCACCTTGCGGTTCCAGTGCAAAATTTGCGGGCTCAAACTCCCCACGAAATCCGAAGAAGTGAAACACAAGCGAAAAATGCATCCTGTTATTAAATTCACATGCGCTGTTTGCGGAAAGAATTTCTGCAATCAGGGAAACTTGAATGTCCATATGAGACAGCACGATCCTTACTACGAGCCTCCTGTTTACAAACGGTTCAAAACTGGGACCTCGAAAGTGAGAAAAGCCTACAACTTCGTGTGCCTGAAATGCAAGCGACATTACGTCTCGGAAACCAACCTCAGCAAACACCTGGAAACCTGCAATGGGGGGTTAATCCGGCCCTTTCCTTGCACCGTGTGCGAGAAAACCTATGTAACCTTTAGAGCCCTGAAACGCCACATACGATGCCACGTCACCCTAAAGTACAAATGCTCCATCTGCGGGCTTGAGCAAGCTACAAAGCACTTGCTGGCTGAACACAAGAAAATCCACGAGCCAGAGAGGAGCGTTTGTCCAGAGTGCGGAAAGGAGTTTCAAAATAAATACAGCCTGAAGTTCCATATGAGGAAACACGATCCCAACTACACGGCGCATGTTTACAAATGCAGGTTTTGCGAGTTTGCTGATATATCAAGGAGGAATTACAacaggcacaggaggtttcacactggggaaggcgcagagttgtacgtgtgcgatatgtgcggaaaggagttgcgctcgaaggcgagttttgataaacacatgcgcatgcataataatatcaagccttactgttgcaagacttgcggaaaggcgtttgtttgttacgatgtttgtaagacgcacgagaggacgcacacgaacgagaaaccgtttctttgcagtttgtgtggaaaggcttacacccagaggtcttcgctggggattcacatgaggtcgcacactggggagaagccgtacggttgtgatatttgcgagaagcggtttacttcgaaagccgcacttactgttcattttaagactcatGGTAGACCGCTTTAA
- Protein Sequence
- MVSRQRDADIWTRDFRMRINSKASLVTSSESEDQNSSKDSPLFVYKKHMERYLETSSKNPSLEHVCKICNRRYLTKRGVHNHMKKHTTLKYECEFCGLKYATKFLEMQHKNESHVDEMFKCKICGLPFHRRSNLRYHTMKHDPNYKPPVYKCNTCSYASGCQSRIECDLCEATFETTYDLCSHKKLHKPRQLPCPRCTKPFYFELLLKKHLETCPHDPTKLFACKLCDKKYLTRDSYANHIKSHFTLRFQCKICGLKLPTKSEEVKHKRKMHPVIKFTCAVCGKNFCNQGNLNVHMRQHDPYYEPPVYKRFKTGTSKVRKAYNFVCLKCKRHYVSETNLSKHLETCNGGLIRPFPCTVCEKTYVTFRALKRHIRCHVTLKYKCSICGLEQATKHLLAEHKKIHEPERSVCPECGKEFQNKYSLKFHMRKHDPNYTAHVYKCRFCEFADISRRNYNRHRRFHTGEGAELYVCDMCGKELRSKASFDKHMRMHNNIKPYCCKTCGKAFVCYDVCKTHERTHTNEKPFLCSLCGKAYTQRSSLGIHMRSHTGEKPYGCDICEKRFTSKAALTVHFKTHGRPL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -