Basic Information

Insect: Philonthus cognatus
Gene Symbol: -
Assembly: GCA_932526485.1
Location: CAKOBG010000006.1:1691374-1697206[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00073 0.15 14.8 4.1 1 23 196 218 196 218 0.97

2 11 2.2e-05 0.0047 19.6 1.5 1 23 224 246 224 246 0.98

3 11 0.00018 0.036 16.8 1.0 3 23 254 275 252 275 0.94

4 11 0.022 4.7 10.2 5.2 1 21 281 301 281 303 0.95

5 11 0.00023 0.047 16.4 1.9 1 23 309 331 309 331 0.99

6 11 2.4e-05 0.0049 19.5 0.6 1 23 337 359 337 359 0.98

7 11 0.00057 0.12 15.2 1.4 1 23 367 390 367 390 0.97

8 11 0.00032 0.066 16.0 2.6 2 23 397 418 396 418 0.97

9 11 0.0003 0.063 16.0 0.3 1 23 424 446 424 446 0.98

10 11 3e-06 0.00063 22.3 3.0 1 23 452 475 452 475 0.97

11 11 3.8e-08 7.9e-06 28.3 0.8 1 23 489 511 489 511 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00073	0.15	14.8	4.1	1	23	196	218	196	218	0.97
2	11	2.2e-05	0.0047	19.6	1.5	1	23	224	246	224	246	0.98
3	11	0.00018	0.036	16.8	1.0	3	23	254	275	252	275	0.94
4	11	0.022	4.7	10.2	5.2	1	21	281	301	281	303	0.95
5	11	0.00023	0.047	16.4	1.9	1	23	309	331	309	331	0.99
6	11	2.4e-05	0.0049	19.5	0.6	1	23	337	359	337	359	0.98
7	11	0.00057	0.12	15.2	1.4	1	23	367	390	367	390	0.97
8	11	0.00032	0.066	16.0	2.6	2	23	397	418	396	418	0.97
9	11	0.0003	0.063	16.0	0.3	1	23	424	446	424	446	0.98
10	11	3e-06	0.00063	22.3	3.0	1	23	452	475	452	475	0.97
11	11	3.8e-08	7.9e-06	28.3	0.8	1	23	489	511	489	511	0.97

Sequence Information

Coding Sequence: ATGGCCGCACAGTTCACCTCTTCACAGATCAAGCTGGAGGGAGTGGAACCTTCGGAAAACGTGACAGAAATCCAATCGTACTTAGAAGGATTCCAGAAGGAAATCGAGGGAGCCGATGGAACTATACAAACTGTTACAGAAATAGACGGTGATGGCGAAGCAGAGGAAGGCACGTACTTCGTAGACCAAGCCGGTCATTATTATTACCAAGCTAAAGGTGACACCCAACCTGTCATGACAGTCATGCCTGGTTTGAACGACGATGAACAAGAGCAAGAATTTATCATCAATCAGGATAATGATGATGAAGAAACTCAAGGCGATAAACAAACGGAAGGAGGAAATTTCCAAAGAATTACTGTAGTGCCGGCTGGGGCTGATGGGAGTTCGAATGAGTTGAGTTATGTGCTTATTGTGCAGCAGCCTGATGACAAGGAAGGGGAACAGACAGACGGCGATCAAGATATGGCAGTCTATGATTTCGATGAGGCTGAGGAGGCGACGATGATAGACTCGGAAGCAGAGGACGACAAGTCCAAGATTGTCAAGATCTTCCCCAGGAAATCTCAGGTGGTAACACAAGCGCACATGTGCAACTATTGCAACTACACTAGCCCCAAGCGTTACCTGCTGTCGCGGCACATGAAGTCCCATTCAGAGGAGAGGCCCCACAAGTGCTCGGTCTGCGAGCGGGGATTCAAGACGCTCGCGTCGCTGCAGAACCACGTTAACACACACACTGGAACCAAGCCGCACCTGTGCAAGTATTGCGAGGCCGCTTTTACTACATCTGgtgaacttgttcgtcacgtgaggtacaagcacacgcatgagaagccgcacaagtgccatgaatgtgactacgccagtgtcgagctgtccaagctgaaacgccacatccggtgtcacacgggagagcgtccgtaccagtgcccccactgcacctatgccagccccgacacattcaaactaaagcggcacctgcggatccacacaggcgagaagccgtacgagtgtgatgtctgccaggccaggttcacacagtccaatagtctaaaggcgcacaaactcacccacaatgTGATTGACAAGCCTGTATTCCAATGTGAACTGTGCCCTACGACATGCGGCCGCAAAACCGACCTCCGCATCCACGTCCAAAAACTCCACACATCGGACAAACCGCTGAAGTGCAAACGGTGCGGGAAGCAATTCCCTGACCGCTACAGCTACAAGCTGCACAACAAGACCCATGAGGGTGAAAAGTGTTTCAAGTGCGACCTCTGTCCTTACGCCTCCATCTCAGCCCGTCACCTGGAATCCCACATGCTGATACACACCGACCAGAAACCGTATCAGTGTTCACAGTGCGATCAATCGTTCAGACAGAAACAGCTGCTGAAGAGGCACCAGAATCTGTACCACAACCCGGCTTACGTGCCGCCGCCGCCCAAAGAGAAGACGCACGAGTGTCCTGAGTGCGGCAGGGCGTTCCGGCACAAGGGGAACCTGATCAGGCACATGGCGATACACGATCCCGAGTCTTGTCTGGAGGAGAAGCAGTTGGCGCTAAAGTTGGGCAGGCAGAAGAAGATCCAGATGATTGACGGGCAACAGGTCGAAGTTATGCCCGGCATCGATTCCGAAGAAGAGGAGGAGGAGGACGAAGATGAGGACATGATGGCCGTTGAAGGTTCGGATGGGCAGCAGTACGTAGTTTTGGAGGTTATACAGTTGGCTGATGGGGAGGAGCAGACTATGGTTGTCGGTGGACAAGCGGAAATCTTGAATGAGAATATGCTGCAAGAACACGATTTAAATGACGAAGATGTTATTAAAGCATTAGAGTCGGCGAGGAGAATAGCGAAAGAAGAAGAGGAGGAAAAGAAAATATCGTCTACGCACGACATGGAAACGTGCTTCGGATTTGATGAGGAGGATGAAGAAGAAGACGAGATGCAGAAAGAATCCATTACATTGTTGGGAATGGACTGA
Protein Sequence: MAAQFTSSQIKLEGVEPSENVTEIQSYLEGFQKEIEGADGTIQTVTEIDGDGEAEEGTYFVDQAGHYYYQAKGDTQPVMTVMPGLNDDEQEQEFIINQDNDDEETQGDKQTEGGNFQRITVVPAGADGSSNELSYVLIVQQPDDKEGEQTDGDQDMAVYDFDEAEEATMIDSEAEDDKSKIVKIFPRKSQVVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHLCKYCEAAFTTSGELVRHVRYKHTHEKPHKCHECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDVCQARFTQSNSLKAHKLTHNVIDKPVFQCELCPTTCGRKTDLRIHVQKLHTSDKPLKCKRCGKQFPDRYSYKLHNKTHEGEKCFKCDLCPYASISARHLESHMLIHTDQKPYQCSQCDQSFRQKQLLKRHQNLYHNPAYVPPPPKEKTHECPECGRAFRHKGNLIRHMAIHDPESCLEEKQLALKLGRQKKIQMIDGQQVEVMPGIDSEEEEEEDEDEDMMAVEGSDGQQYVVLEVIQLADGEEQTMVVGGQAEILNENMLQEHDLNDEDVIKALESARRIAKEEEEEKKISSTHDMETCFGFDEEDEEEDEMQKESITLLGMD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00902440;
90% Identity: iTF_01096838; iTF_01186448;
80% Identity: -