Basic Information

Insect: Philonthus cognatus
Gene Symbol: -
Assembly: GCA_932526485.1
Location: CAKOBG010000308.1:216343-220771[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.6e-05 0.0074 19.0 3.2 2 23 197 218 196 218 0.98

2 11 2.7e-06 0.00057 22.5 1.2 1 23 224 246 224 246 0.99

3 11 0.00012 0.026 17.3 6.2 1 23 254 276 254 276 0.97

4 11 0.00068 0.14 14.9 1.5 1 23 282 304 282 304 0.98

5 11 0.014 2.9 10.8 0.2 1 23 316 338 316 338 0.96

6 11 2.3e-06 0.00048 22.7 3.1 1 23 344 366 344 366 0.96

7 11 2.4e-05 0.005 19.5 0.4 1 23 372 394 372 394 0.99

8 11 1.2e-06 0.00025 23.6 0.6 1 23 400 422 400 422 0.98

9 11 7.9e-05 0.016 17.9 1.5 2 23 429 450 428 450 0.97

10 11 1.9e-05 0.004 19.8 0.1 1 23 456 478 456 478 0.99

11 11 8.3e-08 1.7e-05 27.3 0.5 1 23 484 506 484 506 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.6e-05	0.0074	19.0	3.2	2	23	197	218	196	218	0.98
2	11	2.7e-06	0.00057	22.5	1.2	1	23	224	246	224	246	0.99
3	11	0.00012	0.026	17.3	6.2	1	23	254	276	254	276	0.97
4	11	0.00068	0.14	14.9	1.5	1	23	282	304	282	304	0.98
5	11	0.014	2.9	10.8	0.2	1	23	316	338	316	338	0.96
6	11	2.3e-06	0.00048	22.7	3.1	1	23	344	366	344	366	0.96
7	11	2.4e-05	0.005	19.5	0.4	1	23	372	394	372	394	0.99
8	11	1.2e-06	0.00025	23.6	0.6	1	23	400	422	400	422	0.98
9	11	7.9e-05	0.016	17.9	1.5	2	23	429	450	428	450	0.97
10	11	1.9e-05	0.004	19.8	0.1	1	23	456	478	456	478	0.99
11	11	8.3e-08	1.7e-05	27.3	0.5	1	23	484	506	484	506	0.98

Sequence Information

Coding Sequence: ATGGAAGTGAAAAGTGACCCGAACGCCTTCGATATCAGCAAAATATGCCGGGCCTGTCTGCTCGAGAAGGACGACATGCGGTCCGTCTTCCTGCCGGACGAATCCCTGGGCCTGGCGGTGGGACTAGCCGAAATTCTAATGGGTTTTACCAGTGTACAGATCGAAAACGGAGATGGCTTACCATCTCTACTCTGCATCCAGTGCGCCCATCAAGCCAGTCAATGTTTATCGTTCAAACAACTGTGCGAACAGTCCGACACGAACCTCCGCACATATTTAGGCAAACCTCTAATCCCGAAGCCCTGCAAACAGGAAGCTGAAAACCAACACAGCTCGAATTTAACGGCCCTCCTTTTAGACACCCTGGGTTTAACCGAGTCCTCGGAGGAGAGCGAAGAGGAGGACGACTACCGCGTCGCCGACATGGATTTGATCGACATGAAAAACCTGGACGCCACCGACGAGAAGTTAATCGCACAGCGACAACTCATAAAATCCTCCAAGACGCACAAAGGTAAATCGTCTAAGAAGAAGATTATAGCGAAAACCGGAAAGATCGGTTCGAAGAAAATCAAGCGGAACACTAatcagtgcaacgtttgcaagaagcagtttatcaatttaaaatcgtttcgaaagcatttgcgtacgcacatcgaagataggccgtacaagtgcaaattatgtccgcgcggcttcacggaggagaattatttaaacaaccacatgcgcacgcacataccagaagatcagaaaccgcacgagtgtaaaatatgtaaaaagaggtttattcacacgactttgctgaataagcacatgctcaaacattccggggaaaaaccgtttgtttgtaagatttgcaataaagggtgttacgcggagaacagcttgttgaagcacatgaagattcacgagaagaaggagggggatcctgggttgttgaagcatatctgtgattattgtaagagcgagtttccgaccgctgaggttttggcggtgcacattaagcagcacaccggggacaggccgtttttgtgtaacacttgcggcaagtgcttcccgcagaggtttaatttggagttgcacttgagaacacacacgggtgaaaggccgtttacttgtgaggtttgtcaaaacggctacgtgtctaaagcgagtctgaaaattcacatgagaacacacacgaacgagcggccttttgtctgtgatttctgcggtaaggcgttcagacaatccggagacttgactagccataaacgactgcacggcacagagaaacccATCGAATGTTCCGTGTGTCAAAAAAGATTTACAACTGTGATGAAATTAAAATACcatatgagaaaccacaccggcgagcgaccgtacgtttgtaatatctgcgggcgtggtttcaccgtgaatacgattctattgagacacatgcgggtgcattctggggaacgaccctacgtatgcgtcacttgcggcaaagcattttctcagtcgagtacgctcaatacacacatgAAGGTTCATACACcatcacctaaatatcaattagctgaacaacaacaacagcagcagcagcaacaacaacaacaacaacaacagcaccaacaatgcataccaaagtatcaccaacaaatccagcaaatgcaacCCGAACAATCACGCATAATGCAAAACGACACGACCCGCATGATCTCTAGTGACGGTTCGCGCATTATCACAGACAGCCGATTGATTAATGACAATGCGCACATGCTCAACGTTCAGGATAACGTCGGCACGTATAAAATCGAAACTAAATTCATACCCGACGCTCGACTGTTGGTTAACGTATCGGAACCTCCACCCTTAATCGCACTTAACGATAACAATAGGTTAATAACAAACGATAATAACAGGCTTATGAACGAAGGGCCACGAATTTTATCCGAAAAGTATTTGCCGAACTACGATCAGTACCATCGTGGACATATGTAA
Protein Sequence: MEVKSDPNAFDISKICRACLLEKDDMRSVFLPDESLGLAVGLAEILMGFTSVQIENGDGLPSLLCIQCAHQASQCLSFKQLCEQSDTNLRTYLGKPLIPKPCKQEAENQHSSNLTALLLDTLGLTESSEESEEEDDYRVADMDLIDMKNLDATDEKLIAQRQLIKSSKTHKGKSSKKKIIAKTGKIGSKKIKRNTNQCNVCKKQFINLKSFRKHLRTHIEDRPYKCKLCPRGFTEENYLNNHMRTHIPEDQKPHECKICKKRFIHTTLLNKHMLKHSGEKPFVCKICNKGCYAENSLLKHMKIHEKKEGDPGLLKHICDYCKSEFPTAEVLAVHIKQHTGDRPFLCNTCGKCFPQRFNLELHLRTHTGERPFTCEVCQNGYVSKASLKIHMRTHTNERPFVCDFCGKAFRQSGDLTSHKRLHGTEKPIECSVCQKRFTTVMKLKYHMRNHTGERPYVCNICGRGFTVNTILLRHMRVHSGERPYVCVTCGKAFSQSSTLNTHMKVHTPSPKYQLAEQQQQQQQQQQQQQQQHQQCIPKYHQQIQQMQPEQSRIMQNDTTRMISSDGSRIITDSRLINDNAHMLNVQDNVGTYKIETKFIPDARLLVNVSEPPPLIALNDNNRLITNDNNRLMNEGPRILSEKYLPNYDQYHRGHM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01096825;
90% Identity: -
80% Identity: -